Michael P. Murphy

81.8k total citations · 18 hit papers
535 papers, 56.2k citations indexed

About

Michael P. Murphy is a scholar working on Molecular Biology, Physiology and Pathology and Forensic Medicine. According to data from OpenAlex, Michael P. Murphy has authored 535 papers receiving a total of 56.2k indexed citations (citations by other indexed papers that have themselves been cited), including 349 papers in Molecular Biology, 115 papers in Physiology and 56 papers in Pathology and Forensic Medicine. Recurrent topics in Michael P. Murphy's work include Mitochondrial Function and Pathology (240 papers), ATP Synthase and ATPases Research (74 papers) and Redox biology and oxidative stress (51 papers). Michael P. Murphy is often cited by papers focused on Mitochondrial Function and Pathology (240 papers), ATP Synthase and ATPases Research (74 papers) and Redox biology and oxidative stress (51 papers). Michael P. Murphy collaborates with scholars based in United Kingdom, United States and New Zealand. Michael P. Murphy's co-authors include Robin A.J. Smith, Andrew M. James, Helena M. Cochemé, Richard C. Hartley, Carolyn M. Porteous, Angela Logan, Martin D. Brand, Luke O'neill, Edward T. Chouchani and Tracy A. Prime and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Michael P. Murphy

525 papers receiving 55.4k citations

Hit Papers

How mitochondria produce ... 2001 2026 2009 2017 2008 2016 2001 2022 2006 2.0k 4.0k 6.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. How mitochondria produce reactive oxygen species
    2008 6.2k citations Michael P. Murphy profile →
  2. Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
    2016 1.6k citations Angela Logan, Michael P. Murphy et al. profile →
  3. A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
    2001 1.1k citations Michael P. Murphy et al. profile →
  4. Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
    2022 1.1k citations Michael P. Murphy et al. profile →
  5. Targeting Antioxidants to Mitochondria by Conjugation to Lipophilic Cations
    2006 966 citations Michael P. Murphy, Robin A.J. Smith profile →
  6. Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells
    2001 903 citations Robin A.J. Smith, Michael P. Murphy et al. profile →
  7. Redox Homeostasis and Mitochondrial Dynamics
    2015 670 citations Michael P. Murphy et al. profile →
  8. Selective fluorescent imaging of superoxide in vivo using ethidium-based probes
    2006 645 citations Michael P. Murphy et al. Proceedings of the National Academy of Sciences profile →
  9. Unraveling the Biological Roles of Reactive Oxygen Species
    2011 633 citations Michael P. Murphy, Linda Partridge et al. profile →
  10. Delivery of bioactive molecules to mitochondria in vivo
    2003 605 citations Robin A.J. Smith, Michael P. Murphy et al. Proceedings of the National Academy of Sciences profile →
  11. Mitochondria as a therapeutic target for common pathologies
    2018 603 citations Michael P. Murphy, Richard C. Hartley profile →
  12. A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury
    2016 560 citations Edward T. Chouchani, Victoria R. Pell et al. profile →
  13. Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
    2013 506 citations Edward T. Chouchani, Carmen Methner et al. profile →
  14. Targeting an antioxidant to mitochondria decreases cardiac ischemia‐reperfusion injury
    2005 505 citations Andrew M. James, Robin A.J. Smith et al. profile →
  15. Accumulation of succinate controls activation of adipose tissue thermogenesis
    2018 376 citations Michael P. Murphy, Edward T. Chouchani et al. profile →
  16. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults
    2018 331 citations Michael P. Murphy et al. Hypertension profile →
  17. A break in mitochondrial endosymbiosis as a basis for inflammatory diseases
    2024 76 citations Michael P. Murphy et al. profile →
  18. Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation
    2025 22 citations Hiran A. Prag, Anja V. Gruszczyk et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Michael P. Murphy 33.6k 12.0k 5.1k 4.6k 4.2k 535 56.2k
Dean P. Jones 26.9k 0.8× 7.5k 0.6× 4.1k 0.8× 3.5k 0.8× 7.1k 1.7× 742 54.8k
Helmut Sies 30.1k 0.9× 10.6k 0.9× 3.6k 0.7× 4.2k 0.9× 8.4k 2.0× 657 81.4k
Toren Finkel 30.3k 0.9× 11.4k 1.0× 7.8k 1.5× 6.5k 1.4× 2.4k 0.6× 211 55.4k
Florian Läng 36.0k 1.1× 21.3k 1.8× 2.8k 0.5× 5.2k 1.1× 2.9k 0.7× 1.4k 68.2k
Victor Darley‐Usmar 15.2k 0.5× 10.0k 0.8× 3.2k 0.6× 3.5k 0.8× 4.5k 1.1× 373 33.2k
Sten Orrenius 28.6k 0.8× 4.8k 0.4× 3.5k 0.7× 5.1k 1.1× 4.2k 1.0× 455 51.5k
Walter Wahli 28.5k 0.8× 11.9k 1.0× 6.2k 1.2× 3.2k 0.7× 3.8k 0.9× 325 42.0k
Aldons J. Lusis 30.8k 0.9× 12.1k 1.0× 6.8k 1.3× 10.5k 2.3× 4.2k 1.0× 617 63.9k
Marjorie B. Lees 23.2k 0.7× 10.0k 0.8× 4.9k 1.0× 6.1k 1.3× 7.4k 1.8× 110 65.3k
Csaba Szabó 16.1k 0.5× 11.5k 1.0× 3.8k 0.8× 6.9k 1.5× 13.5k 3.2× 682 51.1k

Countries citing papers authored by Michael P. Murphy

Since Specialization
Citations

This map shows the geographic impact of Michael P. Murphy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael P. Murphy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael P. Murphy more than expected).

Fields of papers citing papers by Michael P. Murphy

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael P. Murphy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael P. Murphy. The network helps show where Michael P. Murphy may publish in the future.

Co-authorship network of co-authors of Michael P. Murphy

This figure shows the co-authorship network connecting the top 25 collaborators of Michael P. Murphy. A scholar is included among the top collaborators of Michael P. Murphy based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael P. Murphy. Michael P. Murphy is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lee, Jordan, Hiran A. Prag, Jiro Abe, et al.. (2025). Local arterial administration of acidified malonate as an adjunct therapy to mechanical thrombectomy in ischemic stroke. Cardiovascular Research. 121(9). 1407–1418. 2 indexed citations
2.
Lennicke, Claudia, Sebastian Grönke, Katja E. Menger, et al.. (2025). Enhancing autophagy by redox regulation extends lifespan in Drosophila. Nature Communications. 16(1). 5379–5379. 2 indexed citations
3.
James, Andrew M., Denis Lacabanne, Martin King, et al.. (2025). TRAM-LAG1-CLN8 family proteins are acyltransferases regulating phospholipid composition. Science Advances. 11(8). eadr3723–eadr3723. 5 indexed citations
4.
Camm, Emily J., Anna Maria Nuzzo, Ana‐Mishel Spiroski, et al.. (2024). In vivo mitochondria‐targeted protection against uterine artery vascular dysfunction and remodelling in rodent hypoxic pregnancy. The Journal of Physiology. 602(6). 1211–1225. 9 indexed citations
5.
Roca, Francisco J., Laura Whitworth, Hiran A. Prag, Michael P. Murphy, & Lalita Ramakrishnan. (2022). Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport. Science. 376(6600). eabh2841–eabh2841. 106 indexed citations
6.
Nuevo‐Tapioles, Cristina, Fulvio Santacatterina, Cristina Núñez de Arenas, et al.. (2021). Effective therapeutic strategies in a preclinical mouse model of Charcot–Marie–Tooth disease. Human Molecular Genetics. 30(24). 2441–2455. 5 indexed citations
7.
Beach, Timothy E., Hiran A. Prag, Angela Logan, et al.. (2020). Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury. Redox Biology. 36. 101640–101640. 51 indexed citations
8.
Jing, Chenzhi, Tomas Castro‐Dopico, Nathan Richoz, et al.. (2020). Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis. Proceedings of the National Academy of Sciences. 117(26). 15160–15171. 153 indexed citations
9.
Greenway, Ryan, Anthony P. Brown, Lenin Arias‐Rodríguez, et al.. (2020). Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments. Proceedings of the National Academy of Sciences. 117(28). 16424–16430. 49 indexed citations
10.
Prag, Hiran A., Duvaraka Kula‐Alwar, John F. Mulvey, et al.. (2020). Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo. Cardiovascular Drugs and Therapy. 36(1). 1–13. 37 indexed citations
11.
Humpton, Timothy J., Gina M. DeNicola, Dan Lü, et al.. (2019). Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer. Cancer Discovery. 9(9). 1268–1287. 139 indexed citations
12.
Criado‐García, Olga, et al.. (2019). Immunological Synapse Formation Induces Mitochondrial Clustering and Mitophagy in Dendritic Cells. The Journal of Immunology. 202(6). 1715–1723. 11 indexed citations
13.
Nuzzo, Anna Maria, Emily J. Camm, Amanda N. Sferruzzi‐Perri, et al.. (2018). Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model. American Journal Of Pathology. 188(12). 2704–2716. 78 indexed citations
14.
Frankenreiter, Sandra, Piotr Bednarczyk, Nadja I. Bork, et al.. (2017). cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels. Circulation. 136(24). 2337–2355. 125 indexed citations
15.
Santini, Emanuela, et al.. (2015). Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice. Journal of Neuroscience. 35(49). 16213–16220. 54 indexed citations
16.
Methner, Carmen, Edward T. Chouchani, Guido Buonincontri, et al.. (2014). Mitochondria Selective S -Nitrosation by Mitochondria-Targeted S -Nitrosothiol Protects Against Post-Infarct Heart Failure in Mouse Hearts. European Journal of Heart Failure. 16(7). 712–717. 44 indexed citations
17.
18.
Sharma, Ashish K., Guanyi Lu, Andrea Jester, et al.. (2012). Experimental Abdominal Aortic Aneurysm Formation Is Mediated by IL-17 and Attenuated by Mesenchymal Stem Cell Treatment. Circulation. 126(11_suppl_1). S38–45. 131 indexed citations
19.
Lin, Mei‐Hui, Lili Tian, Michael P. Murphy, et al.. (2010). Aflibercept Exerts Antivascular Effects and Enhances Levels of Anthracycline Chemotherapy In vivo in Human Acute Myeloid Leukemia Models. Molecular Cancer Therapeutics. 9(10). 2737–2751. 18 indexed citations
20.
Graham, Delyth, Ngan Huynh, Carlene A. Hamilton, et al.. (2009). Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy. Hypertension. 54(2). 322–328. 310 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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