Simon A. Hawley

25.6k citations

59 papers · 20.9k indexed · 15 hit papers · h-index 47

Impact in

Physiology top 0.1%
- Adipose Tissue and Metabolism
Aging top 0.5%

Papers in

Physiology 6
- Adipose Tissue and Metabolism 9
- Calcium signaling and nucleotide metabolism 6
Molecular Biology 56
- Metabolism, Diabetes, and Cancer 52
- PI3K/AKT/mTOR signaling in cancer 8
- Protein Kinase Regulation and GTPase Signaling 6

Co-authors: D. Grahame Hardie Fiona A. Ross Julia M. Corton John G. Gillespie Kirsty J. Mustard John W. Scott David Carling Dario R. Alessi
Journals: Biochemical Journal (8 papers)European Journal of Biochemistry (7 papers)Journal of Biological Chemistry (5 papers)Cell Metabolism (4 papers)Diabetes (4 papers)
Partner nations: United Kingdom United States France

In The Last Decade

Simon A. Hawley

58 papers receiving 20.6k citations

Hit Papers

15 papers align trajectories log scale

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK 2017 · 508 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2017 Nature
2016 Diabetes
2012 Nature Reviews Molecular Cell Biology
2012 Science
2010 Cell Metabolism
2006 The Journal of Physiology
2005 Cell Metabolism
2004 Journal of Clinical Investigation
2004 The EMBO Journal
2003 Journal of Biology
2002 Diabetes
2001 BioEssays
1996 Journal of Biological Chemistry
1995 European Journal of Biochemistry
1995 European Journal of Biochemistry

Peers

Countries citing papers authored by Simon A. Hawley

Since Specialization

Citations

This map shows the geographic impact of Simon A. Hawley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon A. Hawley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon A. Hawley more than expected).

Fields of papers citing papers by Simon A. Hawley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon A. Hawley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon A. Hawley. The network helps show where Simon A. Hawley may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon A. Hawley, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon A. Hawley Line = papers co-authored together Simon A. Hawley links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand Biochemical Journal ·Simon A. Hawley, Fiona M. Russell, D. Grahame Hardie	2024	6
2	BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation International Journal of Molecular Sciences ·Simon A. Hawley, Fiona M. Russell, Fiona A. Ross, D. Grahame Hardie	2023	11
3	Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers Biochemical Journal ·Fiona A. Ross, Simon A. Hawley, Fiona M. Russell, Nicola Goodman, D. Grahame Hardie	2023	4
4	Intact Cell Assays to Monitor AMPK and Determine the Contribution of the AMP-Binding or ADaM Sites to Activation Methods in molecular biology ·Simon A. Hawley, Fiona A. Fyffe, Fiona M. Russell, Graeme J. Gowans, D. Grahame Hardie	2018	8
5	Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK Methods in molecular biology ·Fiona A. Fyffe, Simon A. Hawley, Alexander Gray, D. Grahame Hardie	2018	10
6	Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib Cell chemical biology ·Fiona A. Ross, Simon A. Hawley, Francesca R. Auciello, Graeme J. Gowans, Abdelmadjid Atrih, Douglas J. Lamont, D. Grahame Hardie	2017	49
7	Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK Chemistry & Biology ·Roger W. Hunter, Marc Foretz, Laurent Bultot, Morgan D. Fullerton, Mária Deák, Fiona A. Ross, Simon A. Hawley, Natalia Shpiro, Benoı̂t Viollet, Denís Barron, Bruce E. Kemp, Gregory R. Steinberg, D. Grahame Hardie, Kei Sakamoto	2014	105
8	The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase Science ·Simon A. Hawley, Morgan D. Fullerton, Fiona A. Ross, Jonathan D. Schertzer, Cyrille Chevtzoff, Katherine J. Walker, Mark Peggie, Darya Zibrova, Kevin A. Green, Kirsty J. Mustard, Bruce E. Kemp, Kei Sakamoto, Gregory R. Steinberg, D. Grahame Hardie Hit paper breakdown →	2012	590
9	AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern Chemistry & Biology ·D. Grahame Hardie, Fiona A. Ross, Simon A. Hawley	2012	312
10	Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation Cell Metabolism ·Simon A. Hawley, Fiona A. Ross, Cyrille Chevtzoff, Kevin A. Green, A. Mark Evans, Sarah Fogarty, Mhairi C. Towler, Laura E. Brown, Oluseye A. Ogunbayo, D. Grahame Hardie Hit paper breakdown →	2010	634
11	SnRK1 (SNF1‐related kinase 1) has a central role in sugar and ABA signalling in Arabidopsis thaliana The Plant Journal ·Mathieu Jossier, Jean‐Pierre Bouly, Patrice Meimoun, Alaleh Arjmand, Philippe Lessard, Simon A. Hawley, D. Grahame Hardie, Martine Thomas	2009	269
12	Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice British Journal of Pharmacology ·Mark Mooney, Sarah Fogarty, Claire L. Stevenson, Alison Gallagher, P Palit, Simon A. Hawley, D. Grahame Hardie, Geoffrey D. Coxon, R. D. WAIGH, Rothwelle J. Tate, Alan L. Harvey, B L Furman	2008	57
13	Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase Journal of Biological Chemistry ·Olga Göransson, Andrew McBride, Simon A. Hawley, Fiona A. Ross, Natalia Shpiro, Marc Foretz, Benoı̂t Viollet, D. Grahame Hardie, Kei Sakamoto	2007	353
14	AMP‐activated protein kinase – development of the energy sensor concept The Journal of Physiology ·D. Grahame Hardie, Simon A. Hawley, John W. Scott Hit paper breakdown →	2006	655
15	AMP‐activated protein kinase: the energy charge hypothesis revisited BioEssays ·D. Grahame Hardie, Simon A. Hawley Hit paper breakdown →	2001	642
16	Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio Current Biology ·Wayne A. Wilson, Simon A. Hawley, D. Grahame Hardie	1996	315
17	5′-AMP Activates the AMP-activated Protein Kinase Cascade, and Ca2+/Calmodulin Activates the Calmodulin-dependent Protein Kinase I Cascade, via Three Independent Mechanisms Journal of Biological Chemistry ·Simon A. Hawley, Michele A. Selbert, Elaine G. Goldstein, Arthur Edelman, David Carling, D. Grahame Hardie	1995	362
18	5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells? European Journal of Biochemistry ·Julia M. Corton, John G. Gillespie, Simon A. Hawley, D. Grahame Hardie Hit paper breakdown →	1995	1050
19	Purification of the AMP‐activated protein kinase on ATP‐γ‐Sepharose and analysis of its subunit structure European Journal of Biochemistry ·Stephen Davies, Simon A. Hawley, Angela Woods, David Carling, Timothy Haystead, D. Grahame Hardie	1994	133
20	Activation of rat liver AMP‐activated protein kinase by kinase kinase in a purified, reconstituted system European Journal of Biochemistry ·John Weekes, Simon A. Hawley, Julia M. Corton, David Shugar, D. Grahame Hardie	1994	67

About Simon A. Hawley

Simon A. Hawley is a scholar working on Physiology, Molecular Biology, Surgery, Cell Biology and Physiology, having authored 59 papers that have together received 20.9k indexed citations. Recurring topics across this work include Metabolism, Diabetes, and Cancer (52 papers), Pancreatic function and diabetes (30 papers), Adipose Tissue and Metabolism (9 papers), PI3K/AKT/mTOR signaling in cancer (8 papers), Plant nutrient uptake and metabolism (6 papers), Calcium signaling and nucleotide metabolism (6 papers), Protein Kinase Regulation and GTPase Signaling (6 papers) and Autophagy in Disease and Therapy (6 papers). The work is most often cited by research in Physiology (1.3k citations), Aging (412 citations), Molecular Biology (16.1k citations), Geriatrics and Gerontology (834 citations) and Endocrinology, Diabetes and Metabolism (2.8k citations). Simon A. Hawley has collaborated with scholars based in United Kingdom, United States and France. Frequent co-authors include D. Grahame Hardie, Fiona A. Ross, Julia M. Corton, John G. Gillespie, Kirsty J. Mustard, John W. Scott, David Carling, Dario R. Alessi, Lina Udd and Jérôme Boudeau. Their work appears in journals such as Biochemical Journal, European Journal of Biochemistry, Journal of Biological Chemistry, Cell Metabolism and Diabetes.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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