Douglas B. Kitchen

5.8k citations

45 papers · 4.3k indexed · 1 hit paper · h-index 24

Impact in

Computational Theory and Mathematics top 0.2%
- Computational Drug Discovery Methods
Molecular Biology top 5%
- Protein Structure and Dynamics
- Chemical Synthesis and Analysis

Papers in

Physical and Theoretical Chemistry 7
- Photochemistry and Electron Transfer Studies 4
Computational Theory and Mathematics 8
- Computational Drug Discovery Methods 8

Co-authors: Hélène Decornez Jürgen Bajorath Ronald M. Levy Govindan Subramanian Karsten Krogh‐Jespersen Leland C. Allen James E. Jackson John T. Blair
Journals: The Journal of Physical Chemistry (5 papers)Journal of Medicinal Chemistry (5 papers)Biochemistry (5 papers)Bioorganic & Medicinal Chemistry Letters (4 papers)ChemMedChem (2 papers)
Partner nations: United States Denmark Egypt

In The Last Decade

Douglas B. Kitchen

45 papers receiving 4.1k citations

Hit Papers

align trajectories log scale

Docking and scoring in virtual screening for drug discovery: methods and applications 2004 · 2.8k citations

Peers

Countries citing papers authored by Douglas B. Kitchen

Since Specialization

Citations

This map shows the geographic impact of Douglas B. Kitchen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas B. Kitchen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas B. Kitchen more than expected).

Fields of papers citing papers by Douglas B. Kitchen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas B. Kitchen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas B. Kitchen. The network helps show where Douglas B. Kitchen may publish in the future.

Co-authors

The 25 scholars most cited alongside Douglas B. Kitchen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Douglas B. Kitchen Line = papers co-authored together Douglas B. Kitchen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design Bioorganic & Medicinal Chemistry Letters ·Bryan C. Duffy, Shuang Liu, Greg S. Martin, Ruifang Wang, Shasha Zhao, He Zhao, Cheng Guo, Michael J. Ellis, 施振雄, Olesya A. Kharenko, Karen Norek, Emily M. Gesner, Peter R. Young, Kevin G. McLure, Gregory S. Wagner, L. Damodharan, André White, R.K. Suto, Henrik C. Hansen, Douglas B. Kitchen	2015	21
2	Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC Frontiers in Microbiology ·Ramy K. Aziz, Aytaç KAYADEVİR, Jonathan M. Monk, Elizabeth Brunk, Robert M. Lewis, Kassidy De Jong, Arti Mishra, Hune, Chitkala Satyanarayana, Saravanakumar Dhakshinamoorthy, Dagmar Elaine Kaiser, Douglas B. Kitchen, Jiseon Hwang, Bernhard Ø. Palsson, Pep Charusanti	2015	7
3	The design and synthesis of novel SGLT2 inhibitors: C-glycosides with benzyltriazolopyridinone and phenylhydantoin as the aglycone moieties Bioorganic & Medicinal Chemistry ·Cheng Guo, Min Hu, Russell J. DeOrazio, Alexander Usyatinsky, Ana Catarina Sequeira, Zhenjun Zhang, Jun‐Ho Maeng, Douglas B. Kitchen, FY Pharnaceutical, Dagmar Elaine Kaiser, Yuri L. Khmelnitsky, Andrew J. Mhyre, Peter R. Guzzo, Shuang Liu	2014	36
4	Design, Synthesis, and Evaluation of Nonretinoid Retinol Binding Protein 4 Antagonists for the Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease Journal of Medicinal Chemistry ·Christopher L. Cioffi, Alwarith Al-kharousi, Emily Freeman, Eilis M. Gillespie, Ping Chen, Douglas G. Stafford, Alibordi, Flávia Elaine Soares Ferreira Lombardi, Lei Zhu, Douglas B. Kitchen, Keith D. Barnes, Bóglárka Rácz, Qiong Qin, Enrique L. Michelotti, Charles L. Cywin, William H. Martin, Paul G. Pearson, Graham Johnson, Konstantin Petrukhin	2014	42
5	Early phase drug discovery: Cheminformatics and computational techniques in identifying lead series Bioorganic & Medicinal Chemistry ·Bryan C. Duffy, Lei Zhu, Hélène Decornez, Douglas B. Kitchen	2012	48
6	4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors Bioorganic & Medicinal Chemistry Letters ·Jiangtao Dang, James P. Beck, 俊平原, Mark A. Wolf, Aleksander M. Kamyshnyi, Ning Xi, N. P. Maksimov, E. A. Higgins, Zhicai Yang, J. Gehler, Magdalena Solar, Peter J. Crocker, G. Sacerdoti, Willy Cesar, Douglas B. Kitchen, Mark A. Smith, Richard E. Olson, Shuang Liu, Bruce F. Molino	2012	20
7	The Anticancer Plant Triterpenoid, Avicin D, Regulates Glucocorticoid Receptor Signaling: Implications for Cellular Metabolism PLoS ONE ·Valsala Haridas, Zhixiang Xu, Douglas B. Kitchen, Anna Jiang, Peter C. Michels, Jordan U. Gutterman	2011	17
8	5-Functionalized indazoles as glucocorticoid receptor agonists Bioorganic & Medicinal Chemistry Letters ·Mei Bai, Grant Carr, Russell J. DeOrazio, Thomas Friedrich, Svetlana V. Dobritsa, Ana Catarina Sequeira, Peter R. Guzzo, Douglas B. Kitchen, I. Kasahara, Nidal Alnidami, Maya Stoeva, Alexander Usyatinsky, Mark A. Wolf	2010	12
9	Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitors Bioorganic & Medicinal Chemistry Letters ·Assa Gory, Brian T. Gregg, Douglas B. Kitchen, Полуэктова Ирина Михайловна, V.G. Kravchenko	2010	24
10	Design, Selection, and Evaluation of a General Kinase‐Focused Library ChemMedChem ·Hélène Decornez, L A Laguinge, W. ODELL, A Boeckmann, Junardi, István Hajdú, Sándor Cseh, György Dormán, Douglas B. Kitchen	2009	11
11	Computational approaches for modeling human intestinal absorption and permeability Journal of Molecular Modeling ·Govindan Subramanian, Douglas B. Kitchen	2006	23
12	Computational Techniques for Diversity Analysis and Compound Classification Mini-Reviews in Medicinal Chemistry ·Douglas B. Kitchen, Florence L. Stahura, Jürgen Bajorath	2004	11
13	Docking and scoring in virtual screening for drug discovery: methods and applications Nature Reviews Drug Discovery ·Douglas B. Kitchen, Hélène Decornez, Mohamed Belkaoumi, Jürgen Bajorath Hit paper breakdown →	2004	2754
14	Computational models to predict blood–brain barrier permeation and CNS activity Journal of Computer-Aided Molecular Design ·Govindan Subramanian, Douglas B. Kitchen	2003	59
15	Molecular Modeling of the Aldose Reductase-Inhibitor Complex Based on the X-ray Crystal Structure and Studies with Single-Site-Directed Mutants Journal of Medicinal Chemistry ·Suresh B. Singh, Michael S. Malamas, Thomas C. Hohman, Ramaswamy Nilakantan, Deborah Carper, Douglas B. Kitchen	2000	24
16	Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with In Vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785) Biochemical Pharmacology ·Carolyn Discafani, Marion L. Carroll, M. Brawner Floyd, Irwin Hollander, Zaheed Husain, Bernard D. Johnson, Douglas B. Kitchen, A A Vlasov, Madhu S. Malo, Albert A. Minnick, Ramaswamy Nilakantan, Ru Shen, Ludmila Profumo-Aguiar, Allan Wissner, Lee M. Greenberger	1999	84
17	Ab initio study of the potential energy surface for the interaction of sodium(1+) with molecular hydrogen and the geometries and energies of Na+(H2)n, n = 2-4 The Journal of Physical Chemistry ·Michael F. Falcetta, Adela Morcillo-Cerrato, Cyrus Seyrafi, Douglas B. Kitchen, P. E. Siska	1993	25
18	Stabilization of α-helical secondary structure during high-temperature molecular-dynamics simulations of α-lactalbumin Chemical Physics ·Pei Fan, Dorothea Kominos, Douglas B. Kitchen, Ronald M. Levy, Jean Baum	1991	10
19	Determining local conformational variations in DNA Journal of Molecular Biology ·William J. Metzler, Po-Chang Li, Douglas B. Kitchen, Ronald M. Levy, Arthur Pardi	1990	63
20	Solution structures of proteins from NMR data and modeling: alternative folds for neutrophil peptide 5 Biochemistry ·Ronald M. Levy, Donna A. Bassolino, Douglas B. Kitchen, Arthur Pardi	1989	42

About Douglas B. Kitchen

Douglas B. Kitchen is a scholar working on Physical and Theoretical Chemistry, Computational Theory and Mathematics, Biochemistry, Electrochemistry and Filtration and Separation, having authored 45 papers that have together received 4.3k indexed citations. Recurring topics across this work include Spectroscopy and Quantum Chemical Studies (8 papers), Computational Drug Discovery Methods (8 papers), Protein Structure and Dynamics (7 papers), RNA and protein synthesis mechanisms (4 papers), Photochemistry and Electron Transfer Studies (4 papers), Analytical Chemistry and Chromatography (3 papers), Electrochemical Analysis and Applications (3 papers) and Retinoids in leukemia and cellular processes (3 papers). The work is most often cited by research in Computational Theory and Mathematics (1.7k citations), Molecular Biology (2.5k citations), Organic Chemistry (900 citations), Physical and Theoretical Chemistry (254 citations) and Pharmacology (246 citations). Douglas B. Kitchen has collaborated with scholars based in United States, Denmark and Egypt. Frequent co-authors include Hélène Decornez, Jürgen Bajorath, Ronald M. Levy, Govindan Subramanian, Karsten Krogh‐Jespersen, Leland C. Allen, James E. Jackson, John T. Blair, John Westbrook and Fumio Hirata. Their work appears in journals such as The Journal of Physical Chemistry, Journal of Medicinal Chemistry, Biochemistry, Bioorganic & Medicinal Chemistry Letters and ChemMedChem.

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