Carolyn Discafani

4.1k citations

30 papers · 3.0k indexed · 1 hit paper · h-index 23

Molecular Biology top 5%
Oncology top 2%
Organic Chemistry top 2%
Pulmonary and Respiratory Medicine top 5%
Radiology, Nuclear Medicine and Imaging top 5%

Co-authors: Allan Wissner Philip Frost Bernard D. Johnson Ramaswamy Nilakantan Ru Shen Hwei‐Ru Tsou Marvin F. Reich Sridhar K. Rabindran
Topics: HER2/EGFR in Cancer Research (6 papers)Cancer-related Molecular Pathways (6 papers)Quinazolinone synthesis and applications (5 papers)
Cited by: Oncology Organic Chemistry Genetics
Journals: Journal of the American Chemical Society Nature Medicine Cancer Research
Partner nations: United States Canada

In The Last Decade

Carolyn Discafani

30 papers receiving 2.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Antitumor Activity of HKI-272, an Orally Active, Irreversible Inhibitor of the HER-2 Tyrosine Kinase

2004 503 citations Sridhar K. Rabindran, Carolyn Discafani et al. Cancer Research profile →

Peers

Countries citing papers authored by Carolyn Discafani

Since Specialization

Citations

This map shows the geographic impact of Carolyn Discafani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carolyn Discafani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carolyn Discafani more than expected).

Fields of papers citing papers by Carolyn Discafani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carolyn Discafani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carolyn Discafani. The network helps show where Carolyn Discafani may publish in the future.

Co-authorship network of co-authors of Carolyn Discafani

This figure shows the co-authorship network connecting the top 25 collaborators of Carolyn Discafani. A scholar is included among the top collaborators of Carolyn Discafani based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carolyn Discafani. Carolyn Discafani is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	TTI-237: A Novel Microtubule-Active Compound with In vivo Antitumor Activity 2008 ·Cancer Research ·Carl F. Beyer,Nan Zhang,Richard Hernandez,(unknown),Judy Lucas,Thai Nguyen,Carolyn Discafani,Semiramis Ayral‐Kaloustian,James J. Gibbons	72
2	Synthesis and SAR of 6-chloro-4-fluoroalkylamino-2-heteroaryl-5-(substituted)phenylpyrimidines as anti-cancer agents 2008 ·Bioorganic & Medicinal Chemistry ·Nan Zhang,Semiramis Ayral‐Kaloustian,Thai Nguyen,Richard Hernandez,Judy Lucas,Carolyn Discafani,Carl F. Beyer	25
3	Synthesis, SAR study and biological evaluation of novel pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as anti-proliferative agents 2008 ·Bioorganic & Medicinal Chemistry ·Yanong D. Wang,(unknown),Biqi Wu,S.A. Johnson,Dennis Powell,Miriam Miranda,John P. McGinnis,Carolyn Discafani,Sridhar K. Rabindran,Wendy H.Y. Cheng,Girija Krishnamurthy	34
4	Preclinical Pharmacologic Evaluation of MST-997, an Orally Active Taxane with Superior In vitro and In vivo Efficacy in Paclitaxel- and Docetaxel-Resistant Tumor Models 2006 ·Clinical Cancer Research ·Deepak Sampath,Lee M. Greenberger,Carl F. Beyer,Malathi Hari,Hao Liu,Michelle Baxter,Sharon Yang,(unknown),Carolyn Discafani	18
5	Tumoricidal effect of calicheamicin immuno-conjugates using a passive targeting strategy 2006 ·International Journal of Oncology ·Erwin R. Boghaert,Kiran Khandke,Latha Sridharan,Douglas Armellino,Maureen Dougher,John F. DiJoseph,Arthur Kunz,Philip Hamann,Ashwin Sridharan,S. E. Jones,Carolyn Discafani,Nitin K. Damle	35
6	Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity 2005 ·Journal of Medicinal Chemistry ·Hwei‐Ru Tsou,(unknown),William Hallett,Marvin F. Reich,M. Brawner Floyd,Bernard D. Johnson,Ronald S. Michalak,Ramaswamy Nilakantan,Carolyn Discafani,Jonathan Golas,Sridhar K. Rabindran,Ru Shen,Xiaoqing Shi,Yu‐Fen Wang,Janis Upeslacis,Allan Wissner	246
7	Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells 2005 ·Bioorganic & Medicinal Chemistry Letters ·Lee D. Jennings,Scott L. Kincaid,Yanong D. Wang,Girija Krishnamurthy,Carl F. Beyer,John P. McGinnis,Miriam Miranda,Carolyn Discafani,Sridhar K. Rabindran	70
8	SKI-606, a Src/Abl Inhibitor withIn vivoActivity in Colon Tumor Xenograft Models 2005 ·Cancer Research ·Jennifer M. Golas,Judy Lucas,(unknown),Jonathan Golas,Carolyn Discafani,Latha Sridharan,Erwin R. Boghaert,Kim Arndt,Fei Ye,Diane H. Boschelli,Fangbiao Li,Craig Titsch,Christine Huselton,Indrasish Ray Chaudhuri,Frank Boschelli	115
9	Tubulin inhibitors. Synthesis and biological activity of HTI-286 analogs with B-segment heterosubstituents 2004 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Daniel W. Smith,Arie Zask,Frank Loganzo,Carolyn Discafani,Carl F. Beyer,Lee M. Greenberger,Semiramis Ayral‐Kaloustian	5
10	Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment 2004 ·Bioorganic & Medicinal Chemistry Letters ·Ayako Yamashita,(unknown),Joshua A. Kaplan,(unknown),Frank Loganzo,Richard Hernandez,Carl F. Beyer,Tami Annable,Sylvia Musto,Carolyn Discafani,Arie Zask,Semiramis Ayral‐Kaloustian	16
11	Synthesis and evaluation of 4-Anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade 2003 ·Bioorganic & Medicinal Chemistry Letters ·Dan Berger,Minu Dutia,Dennis Powell,Biqi Wu,Allan Wissner,Diane H. Boschelli,M. Brawner Floyd,Nan Zhang,(unknown),Jeremy I. Levin,Xuemei Du,Donald Wojciechowicz,Carolyn Discafani,Constance Kohler,Steven C. Kim,Larry Feldberg,Karen Collins,Robert Mallon	25
12	Synthesis and Structure−Activity Relationships of 6,7-Disubstituted 4-Anilinoquinoline-3-carbonitriles. The Design of an Orally Active, Irreversible Inhibitor of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor (EGFR) and the Human Epidermal Growth Factor Receptor-2 (HER-2) 2002 ·Journal of Medicinal Chemistry ·Allan Wissner,(unknown),Marvin F. Reich,M. Brawner Floyd,Bernard D. Johnson,Nellie Mamuya,Edward Rosfjord,Carolyn Discafani,Rachel E. Davis,Xiaoqing Shi,Sridhar K. Rabindran,(unknown),Fei Ye,William Hallett,Ramaswamy Nilakantan,Ru Shen,Yu‐Fen Wang,Lee M. Greenberger,Hwei‐Ru Tsou	212
13	mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer. 2001 ·Endocrine Related Cancer ·Ker Yu,Lourdes Toral‐Barza,Carolyn Discafani,(unknown),Jerauld S. Skotnicki,Philip Frost,J J Gibbons	354
14	Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors of Src Kinase Activity 2001 ·Journal of Medicinal Chemistry ·Diane H. Boschelli,Fei Ye,Yanong D. Wang,Minu Dutia,Steve Johnson,Biqi Wu,Karen Miller,Dennis Powell,(unknown),Mairead Young,Mark Tischler,Kim Arndt,Carolyn Discafani,(unknown),Jay Gibbons,(unknown),Judy Lucas,Jennifer M. Weber,Frank Boschelli	179
15	6-Substituted-4-(3-bromophenylamino)quinazolines as Putative Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor (HER-2) Tyrosine Kinases with Enhanced Antitumor Activity 2001 ·Journal of Medicinal Chemistry ·Hwei‐Ru Tsou,Nellie Mamuya,Bernard D. Johnson,Marvin F. Reich,(unknown),Fei Ye,Ramaswamy Nilakantan,Ru Shen,Carolyn Discafani,(unknown),Rachel E. Davis,Frank E. Koehn,Lee M. Greenberger,Yufen Wang,Allan Wissner	227
16	Combinatorial chemoprevention of intestinal neoplasia 2000 ·Nature Medicine ·C Torrance,Peta E. Jackson,Elizabeth A. Montgomery,Kenneth W. Kinzler,Bert Vogelstein,Allan Wissner,Maria Nunes,Philip Frost,Carolyn Discafani	396
17	Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with In Vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785) 1999 ·Biochemical Pharmacology ·Carolyn Discafani,Marion L. Carroll,M. Brawner Floyd,Irwin Hollander,Zaheed Husain,Bernard D. Johnson,Douglas B. Kitchen,(unknown),Madhu S. Malo,Albert A. Minnick,Ramaswamy Nilakantan,Ru Shen,(unknown),Allan Wissner,Lee M. Greenberger	84
18	Functional State of Primary and Secondary Corpora Lutea in Pregnant Mares 1995 ·Biology of Reproduction ·Carolyn Discafani,E.L. Squires,G. D. Niswender	1
19	A quantitative in vivo mouse model used to assay inhibitors of tumor-induced angiogenesis. 1991 ·PubMed ·(unknown),Carolyn Discafani,(unknown),(unknown),Olga Z. Sarre,(unknown),(unknown),M L Plunkett	22
20	Secretory Breast Carcinoma in a Man 1988 ·The American Journal of Surgical Pathology ·Joel A. Roth,Carolyn Discafani,(unknown)	27

About Carolyn Discafani

Carolyn Discafani is a scholar working on Oncology, Equine and Genetics, having authored 30 papers that have together received 3.0k indexed citations. Recurring topics across this work include HER2/EGFR in Cancer Research (6 papers), Cancer-related Molecular Pathways (6 papers) and Quinazolinone synthesis and applications (5 papers). The work is most often cited by research in Oncology (1.4k citations), Organic Chemistry (872 citations) and Genetics (276 citations). Carolyn Discafani has collaborated with scholars based in United States and Canada. Frequent co-authors include Allan Wissner, Philip Frost, Bernard D. Johnson, Ramaswamy Nilakantan, Ru Shen, Hwei‐Ru Tsou, Marvin F. Reich, Sridhar K. Rabindran, M. Brawner Floyd and Yu‐Fen Wang. Their work appears in journals such as Journal of the American Chemical Society, Nature Medicine and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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