Dik van Leenen

5.6k citations

45 papers · 4.1k indexed · 1 hit paper · h-index 29

Molecular Biology top 5%
Endocrine and Autonomic Systems top 0.5%
Physiology top 5%
Plant Science top 5%
Cellular and Molecular Neuroscience top 5%

Co-authors: Frank C. P. Holstege Marian J.A. Groot Koerkamp Patrick Kemmeren D. Bootsma Kumiko Kobayashi André P. M. Eker Akira Yasui Jan de Wit
Topics: Genomics and Chromatin Dynamics (7 papers)Gene expression and cancer classification (6 papers)Bioinformatics and Genomic Networks (6 papers)
Cited by: Aging Endocrine and Autonomic Systems Molecular Biology
Journals: Nature Nucleic Acids Research Nature Communications
Partner nations: Netherlands Germany Japan

In The Last Decade

Dik van Leenen

45 papers receiving 4.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms

1999 1.1k citations Gijsbertus T. J. van der Horst, Manja Muijtjens et al. Nature profile →

Peers

Countries citing papers authored by Dik van Leenen

Since Specialization

Citations

This map shows the geographic impact of Dik van Leenen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dik van Leenen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dik van Leenen more than expected).

Fields of papers citing papers by Dik van Leenen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dik van Leenen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dik van Leenen. The network helps show where Dik van Leenen may publish in the future.

Co-authorship network of co-authors of Dik van Leenen

This figure shows the co-authorship network connecting the top 25 collaborators of Dik van Leenen. A scholar is included among the top collaborators of Dik van Leenen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dik van Leenen. Dik van Leenen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression 2018 ·Cancer Research ·Marten Hornsveld,Lydia M.M. Smits,Maaike Meerlo,Miranda van Amersfoort,Marian J.A. Groot Koerkamp,Dik van Leenen,(unknown),Frank C. P. Holstege,Patrick W.B. Derksen,Boudewijn Burgering,Tobias B. Dansen	60
2	A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions 2015 ·BMC Biology ·Katrin Sameith,(unknown),Marian J.A. Groot Koerkamp,Dik van Leenen,Mariël Brok,Nathalie Brabers,Philip Lijnzaad,Sander R. van Hooff,Joris J. Benschop,Tineke L. Lenstra,Eva Apweiler,Sake van Wageningen,‎Berend Snel,Frank C. P. Holstege,Patrick Kemmeren	15
3	The Two Main Forms of Histiocytic Sarcoma in the Predisposed Flatcoated Retriever Dog Display Variation in Gene Expression 2014 ·PLoS ONE ·(unknown),Frank G. van Steenbeek,Louis C. Penning,Marian J.A. Groot Koerkamp,Dik van Leenen,(unknown),Guy C. M. Grinwis,Gerard R. Rutteman	7
4	Cell cycle population effects in perturbation studies 2014 ·Molecular Systems Biology ·Eoghan O’Duibhir,Philip Lijnzaad,Joris J. Benschop,Tineke L. Lenstra,Dik van Leenen,Marian J.A. Groot Koerkamp,Thanasis Margaritis,Mariël Brok,Patrick Kemmeren,Frank C. P. Holstege	84
5	Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60 2013 ·Nature Communications ·Yuan Gao,Arjen Koppen,Maryam Rakhshandehroo,(unknown),Stan F.J. van de Graaf,Jorg van Loosdregt,Olivier van Beekum,Nicole Hamers,Dik van Leenen,Celia R. Berkers,Ruud Berger,Frank C. P. Holstege,Paul J. Coffer,Arjan B. Brenkman,Huib Ovaa,Eric Kalkhoven	55
6	Gene Expression Profiling of Histiocytic Sarcomas in a Canine Model: The Predisposed Flatcoated Retriever Dog 2013 ·PLoS ONE ·(unknown),(unknown),Frank G. van Steenbeek,Monique E. van Wolferen,Marian J.A. Groot Koerkamp,Dik van Leenen,Guy C. M. Grinwis,Louis C. Penning,Erik A.C. Wiemer,Gerard R. Rutteman	23
7	Balancing of Histone H3K4 Methylation States by the Kdm5c/SMCX Histone Demethylase Modulates Promoter and Enhancer Function 2013 ·Cell Reports ·Nikolay S. Outchkourov,José M. Muiño,Kerstin Kaufmann,Wilfred F. J. van IJcken,Marian J.A. Groot Koerkamp,Dik van Leenen,Petra de Graaf,Frank C. P. Holstege,Frank Grosveld,H. T. Marc Timmers	102
8	Centromere Binding and a Conserved Role in Chromosome Stability for SUMO-Dependent Ubiquitin Ligases 2013 ·PLoS ONE ·Loes A. L. van de Pasch,(unknown),Wilco Nijenhuis,Nathalie Brabers,Dik van Leenen,Philip Lijnzaad,Markus Brown,(unknown),Yves Barral,Geert J.P.L. Kops,Frank C. P. Holstege	26
9	Aberrant Gene Expression in Dogs with Portosystemic Shunts 2013 ·PLoS ONE ·Frank G. van Steenbeek,(unknown),Guy C. M. Grinwis,Anne Kummeling,(unknown),Marian J.A. Groot Koerkamp,Dik van Leenen,Frank C. P. Holstege,Louis C. Penning,Jan Jaap Rothuizen,Peter A. J. Leegwater,Bart Spee	23
10	The Role of Ctk1 Kinase in Termination of Small Non-Coding RNAs 2013 ·PLoS ONE ·Tineke L. Lenstra,Agnieszka Tudek,Sandra Clauder‐Münster,Zhenyu Xu,Spyridon T. Pachis,Dik van Leenen,Patrick Kemmeren,Lars M. Steinmetz,Domenico Libri,Frank C. P. Holstege	16
11	The Specificity and Topology of Chromatin Interaction Pathways in Yeast 2011 ·Molecular Cell ·Tineke L. Lenstra,Joris J. Benschop,Tae Soo Kim,Julia M. Schulze‐Hentrich,Nathalie Brabers,Thanasis Margaritis,Loes A. L. van de Pasch,Sebastiaan van Heesch,Mariël Brok,Marian J.A. Groot Koerkamp,(unknown),Dik van Leenen,Katrin Sameith,Sander R. van Hooff,Philip Lijnzaad,Patrick Kemmeren,Thomas Hentrich,Michael S. Kobor,Stephen Buratowski,Frank C. P. Holstege	181
12	Early host responses to avian influenza A virus are prolonged and enhanced at transcriptional level depending on maturation of the immune system 2010 ·Molecular Immunology ·Sylvia S. Reemers,Dik van Leenen,Marian J.A. Groot Koerkamp,(unknown),(unknown),Willem van Eden,Lonneke Vervelde	55
13	Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity 2009 ·Nature Chemical Biology ·Tobias B. Dansen,Lydia M.M. Smits,(unknown),Peter L.J. de Keizer,Dik van Leenen,Marian J.A. Groot Koerkamp,(unknown),Amanda Meppelink,Arjan B. Brenkman,Junji Yodoi,Frank C. P. Holstege,Boudewijn Burgering	165
14	Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification 2008 ·Nucleic Acids Research ·Harm van Bakel,Folkert J. van Werven,Marijana Radonjić,Mariël Brok,Dik van Leenen,Frank C. P. Holstege,H. T. Marc Timmers	36
15	cDNA microarray profiles of canine mammary tumour cell lines reveal deregulated pathways pertaining to their phenotype 2008 ·Animal Genetics ·Nagesha Rao,Monique E. van Wolferen,(unknown),Dik van Leenen,Marian J.A. Groot Koerkamp,Frank C. P. Holstege,Jan A. Mol	27
16	Dissection of a metastatic gene expression signature into distinct components 2006 ·Genome biology ·Paul Roepman,(unknown),Dik van Leenen,Roel A. de Weger,J. Alain Kummer,Piet J. Slootweg,Frank C. P. Holstege	33
17	Mediator Expression Profiling Epistasis Reveals a Signal Transduction Pathway with Antagonistic Submodules and Highly Specific Downstream Targets 2005 ·Molecular Cell ·Jeroen van de Peppel,Nienke Kettelarij,Harm van Bakel,Thessa T. J. P. Kockelkorn,Dik van Leenen,Frank C. P. Holstege	177
18	Twenty-two novel mutations in the lysosomal ?-glucosidase gene (GAA) underscore the genotype-phenotype correlation in glycogen storage disease type II 2003 ·Human Mutation ·M M Hermans,Dik van Leenen,Marian A. Kroos,Clare Beesley,Ans T. van der Ploeg,Hitoshi Sakuraba,Ron A. Wevers,(unknown),Helen Michelakakis,Edwin P. Kirk,Janice M. Fletcher,N. U. Bosshard,Lina Basel‐Vanagaite,G. T. N. Besley,Arnold Reuser	113
19	Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythmsbreakdown → 1999 ·Nature ·Gijsbertus T. J. van der Horst,Manja Muijtjens,Kumiko Kobayashi,Riya Takano,Shin-ichiro Kanno,Masashi Takao,Jan de Wit,Anton Verkerk,André P. M. Eker,Dik van Leenen,Ruud M. Buijs,D. Bootsma,Jan H.J. Hoeijmakers,Akira Yasui	1101
20	Mutation Detection in Glycogen Storage Disease Type II by RT-PCR and Automated Sequencing 1997 ·Biochemical and Biophysical Research Communications ·M M Hermans,Dik van Leenen,Marian A. Kroos,Arnold Reuser	21

About Dik van Leenen

Dik van Leenen is a scholar working on Aging, Molecular Biology and Endocrine and Autonomic Systems, having authored 45 papers that have together received 4.1k indexed citations. Recurring topics across this work include Genomics and Chromatin Dynamics (7 papers), Gene expression and cancer classification (6 papers) and Bioinformatics and Genomic Networks (6 papers). The work is most often cited by research in Aging (281 citations), Endocrine and Autonomic Systems (962 citations) and Molecular Biology (2.2k citations). Dik van Leenen has collaborated with scholars based in Netherlands, Germany and Japan. Frequent co-authors include Frank C. P. Holstege, Marian J.A. Groot Koerkamp, Patrick Kemmeren, D. Bootsma, Kumiko Kobayashi, André P. M. Eker, Akira Yasui, Jan de Wit, Jan H.J. Hoeijmakers and Masashi Takao. Their work appears in journals such as Nature, Nucleic Acids Research and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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