Jay S. Desgrosellier

6.1k total citations · 2 hit papers
30 papers, 4.9k citations indexed

About

Jay S. Desgrosellier is a scholar working on Molecular Biology, Oncology and Immunology and Allergy. According to data from OpenAlex, Jay S. Desgrosellier has authored 30 papers receiving a total of 4.9k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 14 papers in Oncology and 12 papers in Immunology and Allergy. Recurrent topics in Jay S. Desgrosellier's work include Cell Adhesion Molecules Research (12 papers), Cancer Cells and Metastasis (9 papers) and TGF-β signaling in diseases (4 papers). Jay S. Desgrosellier is often cited by papers focused on Cell Adhesion Molecules Research (12 papers), Cancer Cells and Metastasis (9 papers) and TGF-β signaling in diseases (4 papers). Jay S. Desgrosellier collaborates with scholars based in United States and China. Jay S. Desgrosellier's co-authors include David A. Cheresh, Laetitia Seguin, Sara M. Weis, Joey V. Barnett, Jacqueline Lesperance, Sanford J. Shattil, Miller Huang, Steven Lau, David J. Shields and Shumei Kato and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Jay S. Desgrosellier

29 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Integrins in cancer: biological implications and therapeutic opportunities

2009 2.9k citations Jay S. Desgrosellier, David A. Cheresh Nature reviews. Cancer profile →
Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance

2015 538 citations Laetitia Seguin, Jay S. Desgrosellier et al. Trends in Cell Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jay S. Desgrosellier United States	19	2.7k	1.7k	1.6k	789	770	30	4.9k
Dwayne G. Stupack United States	46	4.4k 1.6×	2.3k 1.3×	1.5k 0.9×	1.5k 1.9×	1.2k 1.6×	109	7.3k
Brunhilde Felding‐Habermann United States	28	2.4k 0.9×	1.0k 0.6×	2.0k 1.2×	598 0.8×	1.1k 1.4×	43	5.4k
Ute Reuning Germany	34	1.8k 0.7×	1.3k 0.8×	1.2k 0.7×	396 0.5×	1.5k 2.0×	83	4.3k
Nils Cordes Germany	40	2.2k 0.8×	1.3k 0.8×	1.9k 1.2×	1.1k 1.4×	815 1.1×	132	4.5k
Flavio Curnis Italy	34	2.1k 0.8×	683 0.4×	1.5k 0.9×	308 0.4×	425 0.6×	79	3.9k
Satyajit K. Mitra United States	8	2.4k 0.9×	2.3k 1.3×	863 0.5×	2.0k 2.5×	701 0.9×	12	4.8k
Margareta M. Mueller Germany	31	1.8k 0.7×	418 0.2×	1.7k 1.1×	437 0.6×	1.0k 1.3×	48	4.6k
Achim Krüger Germany	45	2.6k 1.0×	631 0.4×	2.1k 1.3×	328 0.4×	2.2k 2.9×	111	5.8k
Frédéric Saltel France	34	2.1k 0.8×	937 0.5×	1.0k 0.7×	1.5k 1.9×	480 0.6×	73	4.4k
Jasti S. Rao United States	54	4.4k 1.6×	1.2k 0.7×	2.4k 1.5×	743 0.9×	3.8k 4.9×	169	8.3k

Countries citing papers authored by Jay S. Desgrosellier

Since Specialization

Citations

This map shows the geographic impact of Jay S. Desgrosellier's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jay S. Desgrosellier with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jay S. Desgrosellier more than expected).

Fields of papers citing papers by Jay S. Desgrosellier

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jay S. Desgrosellier. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jay S. Desgrosellier. The network helps show where Jay S. Desgrosellier may publish in the future.

Co-authorship network of co-authors of Jay S. Desgrosellier

This figure shows the co-authorship network connecting the top 25 collaborators of Jay S. Desgrosellier. A scholar is included among the top collaborators of Jay S. Desgrosellier based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jay S. Desgrosellier. Jay S. Desgrosellier is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Klemke, Richard, et al.. (2025). A dataset of chronic nicotine-induced genes in breast cancer cells. Data in Brief. 60. 111573–111573. 1 indexed citations

Klemke, Richard, et al.. (2025). S100A8/A9 innate immune signaling as a distinct mechanism driving progression of smoking-related breast cancers. Oncogene. 44(15). 1051–1062. 2 indexed citations

Desgrosellier, Jay S., et al.. (2024). Chromosomal instability as an architect of the cancer stemness landscape. Frontiers in Cell and Developmental Biology. 12. 1450614–1450614. 1 indexed citations

Sun, Qi, et al.. (2022). Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1. npj Breast Cancer. 8(1). 5–5. 13 indexed citations

Sun, Qi, Yu‐Fen Wang, & Jay S. Desgrosellier. (2019). Combined Bcl-2/Src inhibition synergize to deplete stem-like breast cancer cells. Cancer Letters. 457. 40–46. 20 indexed citations

Seguin, Laetitia, Maria F. Camargo, Hiromi I. Wettersten, et al.. (2017). Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers. Cancer Discovery. 7(12). 1464–1479. 84 indexed citations

Seguin, Laetitia, Jay S. Desgrosellier, Sara M. Weis, & David A. Cheresh. (2015). Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends in Cell Biology. 25(4). 234–240. 538 indexed citations breakdown →

Seguin, Laetitia, Shumei Kato, Aleksandra Franovic, et al.. (2014). Abstract 1916: β3 integrin/KRAS/RalB complex drives tumor stemness and resistance to EGFR inhibition. Cancer Research. 74(19_Supplement). 1916–1916. 10 indexed citations

Seguin, Laetitia, Shumei Kato, Aleksandra Franovic, et al.. (2014). An integrin β3–KRAS–RalB complex drives tumour stemness and resistance to EGFR inhibition. Nature Cell Biology. 16(5). 457–468. 298 indexed citations

10.

Desgrosellier, Jay S., Jacqueline Lesperance, Laetitia Seguin, et al.. (2014). Integrin αvβ3 Drives Slug Activation and Stemness in the Pregnant and Neoplastic Mammary Gland. Developmental Cell. 30(3). 295–308. 78 indexed citations

11.

Huang, Miller, Sudarshan Anand, Jay S. Desgrosellier, et al.. (2011). EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene. 31(22). 2783–2793. 57 indexed citations

12.

Shields, David J., Jay S. Desgrosellier, Ainhoa Mielgo, et al.. (2011). Oncogenic Ras/Src cooperativity in pancreatic neoplasia. Oncogene. 30(18). 2123–2134. 58 indexed citations

13.

Shields, David J., Sherry Niessen, Eric A. Murphy, et al.. (2009). RBBP9: A tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proceedings of the National Academy of Sciences. 107(5). 2189–2194. 52 indexed citations

14.

Desgrosellier, Jay S. & David A. Cheresh. (2009). Integrins in cancer: biological implications and therapeutic opportunities. Nature reviews. Cancer. 10(1). 9–22. 2908 indexed citations breakdown →

15.

Desgrosellier, Jay S., Leo A. Barnes, David J. Shields, et al.. (2009). An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nature Medicine. 15(10). 1163–1169. 235 indexed citations

16.

Desgrosellier, Jay S., Nathan A. Mundell, Maureen A. McDonnell, Harold L. Moses, & Joey V. Barnett. (2005). Activin receptor-like kinase 2 and Smad6 regulate epithelial–mesenchymal transformation during cardiac valve formation. Developmental Biology. 280(1). 201–210. 68 indexed citations

17.

Barnett, Joey V. & Jay S. Desgrosellier. (2003). Early events in valvulogenesis: A signaling perspective. Birth Defects Research Part C Embryo Today Reviews. 69(1). 58–72. 73 indexed citations

18.

Desgrosellier, Jay S., et al.. (2002). Transforming Growth Factor β (TGFβ) Signaling via Differential Activation of Activin Receptor-like Kinases 2 and 5 during Cardiac Development. Journal of Biological Chemistry. 277(51). 50183–50189. 14 indexed citations

19.

Russo, James E., et al.. (2002). 4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal. BMC Pharmacology. 2(1). 4–4. 18 indexed citations

20.

Ayala, Julio E., Ryan S. Streeper, Jay S. Desgrosellier, et al.. (1999). Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence.. Diabetes. 48(9). 1885–1889. 101 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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