David D. Christ

3.0k citations

49 papers · 1.9k indexed · h-index 25

Impact in

Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
Biological Psychiatry top 5%

Papers in

Pharmacology 16
- Pharmacogenetics and Drug Metabolism 15
Biological Psychiatry 2

Co-authors: J G Kenna L R Pohl Hiroaki Satoh Robert Newton Maryanne Covington Mingxin Qian Rui‐Qin Liu Hiroshi Satoh
Journals: Bioorganic & Medicinal Chemistry Letters (10 papers)Drug Metabolism and Disposition (9 papers)Journal of Medicinal Chemistry (5 papers)Journal of Pharmacology and Experimental Therapeutics (3 papers)Xenobiotica (2 papers)
Partner nations: United States Germany Switzerland

In The Last Decade

David D. Christ

49 papers receiving 1.9k citations

Peers

Countries citing papers authored by David D. Christ

Since Specialization

Citations

This map shows the geographic impact of David D. Christ's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David D. Christ with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David D. Christ more than expected).

Fields of papers citing papers by David D. Christ

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David D. Christ. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David D. Christ. The network helps show where David D. Christ may publish in the future.

Co-authors

The 25 scholars most cited alongside David D. Christ, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David D. Christ Line = papers co-authored together David D. Christ links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE): Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1′ substituents Bioorganic & Medicinal Chemistry Letters ·Zhonghui Lu, Gregory R. Ott, Rajan Anand, Rui‐Qin Liu, Maryanne Covington, Krishna Vaddi, Mingxin Qian, Robert Newton, David D. Christ, James M. Trzăskos, James J.‐W. Duan	2008	53
2	α,β-Cyclic-β-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE) Bioorganic & Medicinal Chemistry Letters ·Gregory R. Ott, Naoyuki Asakawa, Rui‐Qin Liu, Maryanne Covington, Mingxin Qian, Krishna Vaddi, Robert Newton, James M. Trzăskos, David D. Christ, Laurine G. Galya, Thomas Scholz, Will Marshall, James J.‐W. Duan	2008	13
3	A new 4-(2-methylquinolin-4-ylmethyl)phenyl P1′ group for the β-amino hydroxamic acid derived TACE inhibitors Bioorganic & Medicinal Chemistry Letters ·Xiaotao Chen, Ares Osborn, TANYU Hikmet, Chu‐Biao Xue, Rui‐Qin Liu, Maryanne Covington, Mingxin Qian, Krishna Vaddi, David D. Christ, Fandi Ahmad, Maria Ribadeneira, James M. Trzăskos, Robert Newton, Carl P. Decicco, James J.‐W. Duan	2007	13
4	Glucuronidation in the chimpanzee (*Pan troglodytes): Studies with acetaminophen, oestradiol and morphine Xenobiotica* ·Harvey Wong, (unknown), James E. Grace, Matthew Wright, (unknown), (unknown), Francisco Díaz-González, Scott Grossman, (unknown), (unknown), (unknown), S A Bai, David D. Christ, (unknown), (unknown), (unknown), (unknown)	2006	5
5	THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION Drug Metabolism and Disposition ·Harvey Wong, Scott Grossman, Stephen A. Bai, Sharon Diamond, Matthew Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram, David D. Christ	2004	21
6	Potent and selective aggrecanase inhibitors containing cyclic P1 substituents Bioorganic & Medicinal Chemistry Letters ·Robert J. Cherney, Ruowei Mo, Dayton T. Meyer, Li Wang, Wenqing Yao, Zelda R. Wasserman, Rui‐Qin Liu, Maryanne Covington, Micky D. Tortorella, Elizabeth C. Arner, Mingxin Qian, David D. Christ, James M. Trzăskos, Robert Newton, R. L. Magolda, Carl P. Decicco	2003	27
7	Potent P1′ biphenylmethyl substituted aggrecanase inhibitors Bioorganic & Medicinal Chemistry Letters ·Wenqing Yao, Michael C. Chao, Zelda R. Wasserman, Takayuki Dohke, Maryanne Covington, Robert Newton, David D. Christ, Ruth R. Wexler, Carl P. Decicco	2002	27
8	Interaction of Ritonavir on Tissue Distribution of a [14C]L-Valinamide, a Potent Human Immunodeficiency Virus-1 Protease Inhibitor, in Rats Using Quantitative Whole-Body Autoradiography Drug Metabolism and Disposition ·Eric Solon, Suresh K. Balani, Gang Luo, Tian J. Yang, Swomin Sabnam, Lifei Wang, I. Langevin, Sharon Diamond, David D. Christ, Liang‐Shang Gan, Frank W. Lee	2002	10
9	Liquid Chromatography/Mass Spectrometry and High-Field Nuclear Magnetic Resonance Characterization of Novel Mixed Diconjugates of the Non-nucleoside Human Immunodeficiency Virus-1 Reverse Transcriptase Inhibitor, Efavirenz Drug Metabolism and Disposition ·Abdul Mutlib, Asish Choudhary, Gregory A. Nemeth, Ada Riddlesbarger, David D. Christ	1999	29
10	In vitro and in vivo effects of the arylamine human immunodeficiency virus protease inhibitor 4R-(4alpha,5alpha,6beta, 7beta)-1-[(3-(1-imidazoylcarbamoyl)phenyl)methyl]-3-[(3-aminophenyl)m ethyl]hexahydro-5,6-dihydroxy-4,7-bis(phenylmethyl)-2H-1, 3-diazepin-2-one (SD894) on rat hepatic cytochrome P450 2B and 3A. PubMed ·Mary F. Grubb, Vidushi Vatsa, David D. Christ	1997	3
11	Pharmacokinetic-Pharmacodynamic Relations of Losartan and EXP3174 in a Porcine Animal Model Journal of Cardiovascular Pharmacology ·B. E. Smith, Kianna Marie Middleton, Peter W. Hellyer, David D. Christ, Stephen A. Bai	1997	11
12	Nonpeptide Angiotensin II Receptor Antagonist: Pharmacokinetics and Pharmacodynamics in Rats of EXP3174, an Active Metabolite of Losartan Pharmacology ·Pancras C. Wong, David D. Christ, Nancy Wong, Gilbert N. Lam	1996	10
13	Human Plasma Protein Binding of the Angiotensin II Receptor Antagonist Losartan Potassium (DuP 753/MK 954) and Its Pharmacologically Active Metabolite EXP3174 The Journal of Clinical Pharmacology ·David D. Christ	1995	47
14	The pharmacokinetics and pharmacodynamics of the angiotensin II receptor antagonist losartan potassium (DuP 753/MK 954) in the dog. Journal of Pharmacology and Experimental Therapeutics ·David D. Christ, P C Wong, Y. Nancy Wong, Абдиев К. Ж., Check Y. Quon, Gilbert N. Lam	1994	44
15	Induction of cytochromes P-450 2B and 3A in mice following the dietary administration of the novel cognitive enhancer linopirdine. Drug Metabolism and Disposition ·Vidushi Vatsa, Marcelo Devenutte Ávila, James P. O’Neil, Gilbert N. Lam, David D. Christ	1994	4
16	Enhancement of losartan (DuP 753)-induced angiotensin II receptor antagonism by PD123177 in rats European Journal of Pharmacology ·Parnduangjai Suwanyotee, David D. Christ, Pieter B.M.W.M. Timmermans	1992	17
17	Pharmacokinetics and metabolism of the pharmacologically active 4'-hydroxylated metabolite of propranolol in the dog. Drug Metabolism and Disposition ·David D. Christ, U. Kristina Walle, John E. Oatis, Thomas Walle	1990	5
18	Neoantigens Associated with Halothane Hepatitis Drug Metabolism Reviews ·Lance R. Pohl, J G Kenna, Hiroko Satoh, David D. Christ, Jackie L. Martin	1989	79
19	The Immunologic and Metabolic Basis of Drug Hypersensitivities The Annual Review of Pharmacology and Toxicology ·L R Pohl, Hiroshi Satoh, David D. Christ, J G Kenna	1988	143
20	Stereoselective sulfate conjugation of 4-hydroxypropranolol in vitro by different species. Drug Metabolism and Disposition ·David D. Christ, Thomas Walle	1985	10

About David D. Christ

David D. Christ is a scholar working on Pharmacology, Biological Psychiatry, Developmental Neuroscience, Behavioral Neuroscience and Oncology, having authored 49 papers that have together received 1.9k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (15 papers), Drug Transport and Resistance Mechanisms (9 papers), Receptor Mechanisms and Signaling (7 papers), HIV/AIDS drug development and treatment (6 papers), Chemical Synthesis and Analysis (6 papers), Computational Drug Discovery Methods (5 papers), Cytokine Signaling Pathways and Interactions (4 papers) and Analytical Chemistry and Chromatography (3 papers). The work is most often cited by research in Pharmacology (472 citations), Biological Psychiatry (76 citations), Behavioral Neuroscience (108 citations), Anesthesiology and Pain Medicine (115 citations) and Developmental Neuroscience (83 citations). David D. Christ has collaborated with scholars based in United States, Germany and Switzerland. Frequent co-authors include J G Kenna, L R Pohl, Hiroaki Satoh, Robert Newton, Maryanne Covington, Mingxin Qian, Rui‐Qin Liu, Hiroshi Satoh, Carl P. Decicco and Lance R. Pohl. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Drug Metabolism and Disposition, Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and Xenobiotica.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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