Abdul Mutlib

3.4k citations

61 papers · 2.5k indexed · h-index 24

Impact in

Pharmacology top 0.2%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
- Cholinesterase and Neurodegenerative Diseases
Pharmaceutical Science top 2%

Papers in ⓘ

Pharmacology 21
- Pharmacogenetics and Drug Metabolism 19
- Drug-Induced Hepatotoxicity and Protection 7
Biochemistry 8

Co-authors: Robert Espina (14 shared papers)Amit S. Kalgutkar (3 shared papers)Joseph T. Strupczewski (2 shared papers)Christopher L. Shaffer (2 shared papers)Yasuhiro Nakai (1 shared paper)Jason Boer (1 shared paper)Deepak Dalvie (1 shared paper)Ernesto Callegari (1 shared paper)
Journals: Chemical Research in Toxicology (20 papers)Drug Metabolism and Disposition (12 papers)Journal of Pharmacology and Experimental Therapeutics (4 papers)Journal of Mass Spectrometry (2 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)
Partner nations: United States Canada Australia

In The Last Decade

Abdul Mutlib

61 papers receiving 2.4k citations

Peers

Countries citing papers authored by Abdul Mutlib

Since Specialization

Citations

This map shows the geographic impact of Abdul Mutlib's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Abdul Mutlib with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Abdul Mutlib more than expected).

Fields of papers citing papers by Abdul Mutlib

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Abdul Mutlib. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Abdul Mutlib. The network helps show where Abdul Mutlib may publish in the future.

Co-authors

The 25 scholars most cited alongside Abdul Mutlib, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Abdul Mutlib Line = papers co-authored together Abdul Mutlib links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 61 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Comprehensive Listing of Bioactivation Pathways of Organic Functional Groups Current Drug Metabolism ·Amit S. Kalgutkar, Iain Gardner, R. Scott Obach, Christopher L. Shaffer, Ernesto Callegari, Kirk R. Henne, Abdul Mutlib, Deepak Dalvie, Jae S. Lee, Yasuhiro Nakai, John P. O’Donnell, Jason Boer, Shawn Harriman	2005	435
2	Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine. Journal of Pharmacology and Experimental Therapeutics ·Gina M. Bores, Francis P. Huger, Wayne W. Petko, Abdul Mutlib, Fernando Camacho, Douglas K. Rush, David E. Selk, V Wolf, Raymond W. Kosley, Luther Davis, Hugo M. Vargas	1996	222
3	Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies Chemical Research in Toxicology ·Abdul Mutlib	2008	178
4	Identification and Characterization of Efavirenz Metabolites by Liquid Chromatography/Mass Spectrometry and High Field NMR: Species Differences in the Metabolism of Efavirenz Drug Metabolism and Disposition ·Abdul Mutlib, Hua Chen, Gregory A. Nemeth, Jay A. Markwalder, Steven P. Seitz, L.‐S. Gan, David D. Christ	1999	113
5	Metabolism of Capsaicin by Cytochrome P450 Produces Novel Dehydrogenated Metabolites and Decreases Cytotoxicity to Lung and Liver Cells Chemical Research in Toxicology ·Christopher A. Reilly, William J. Ehlhardt, David A. Jackson, Palaniappan Kulanthaivel, Abdul Mutlib, Robert Espina, David E. Moody, Dennis J. Crouch, Garold S. Yost	2003	107
6	Late sodium current block for drug‐induced long QT syndrome: Results from a prospective clinical trial Clinical Pharmacology & Therapeutics ·Lars Johannesen, José Vicente, Mason Jw, Cassandra Erato, Carlos Sanabria, Kristin Waite-Labott, M Hong, J Lin, Pan Guo, Abdul Mutlib, Jian Wang, WJ Crumb, Ksenia Blinova, Dulciana Chan, Jayna Stohlman, Jeff Florian, Martin Ugander, Norman Stockbridge, DG Strauss	2015	107
7	Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen−Induced Hepatotoxicity Chemical Research in Toxicology ·Abdul Mutlib, Theunis C. Goosen, Jonathan Bauman, J. Andrew Williams, Shaila Kulkarni, Seva E. Kostrubsky	2006	95
8	Inhibition of Hepatobiliary Transport as a Predictive Method for Clinical Hepatotoxicity of Nefazodone Toxicological Sciences ·Seva E. Kostrubsky, Stephen C. Strom, Amit S. Kalgutkar, Shaila Kulkarni, James Atherton, Rouchelle Mireles, Bo Feng, Raylene Kubik, Janean Hanson, Ellen Urda, Abdul Mutlib	2006	91
9	Nuclear Magnetic Resonance Spectroscopy as a Quantitative Tool To Determine the Concentrations of Biologically Produced Metabolites: Implications in Metabolites in Safety Testing Chemical Research in Toxicology ·Robert Espina, Linning Yu, Jianyao Wang, Zeen Tong, Sarvesh C. Vashishtha, Rasmy Talaat, JoAnn Scatina, Abdul Mutlib	2008	72
10	Application of hyphenated LC/NMR and LC/MS techniques in rapid identification of in vitro and in vivo metabolites of iloperidone. Drug Metabolism and Disposition ·Abdul Mutlib, Joseph T. Strupczewski, Susan M. Chesson	1995	68
11	The Species-Dependent Metabolism of Efavirenz Produces a Nephrotoxic Glutathione Conjugate in Rats Toxicology and Applied Pharmacology ·Abdul Mutlib, Ronald J. Gerson, Paul C. Meunier, Patrick J. Haley, Hao Chen, Lawrence S. Gan, Marc H. Davies, Brian Gemzik, David D. Christ, David F. Krahn, Jay A. Markwalder, Steven P. Seitz, Richard T. Robertson, Gerald T. Miwa	2000	62
12	Obtaining Exposures of Metabolites in Preclinical Species through Plasma Pooling and Quantitative NMR: Addressing Metabolites in Safety Testing (MIST) Guidance without Using Radiolabeled Compounds and Chemically Synthesized Metabolite Standards Chemical Research in Toxicology ·Karthick Vishwanathan, Kathlene Babalola, Jack Wang, Robert Espina, Linning Yu, Adedayo Adedoyin, Rasmy Talaat, Abdul Mutlib, JoAnn Scatina	2008	61
13	Application of stable isotope labeled glutathione and rapid scanning mass spectrometers in detecting and characterizing reactive metabolites Rapid Communications in Mass Spectrometry ·Abdul Mutlib, Wing Lam, Jim Atherton, Hao Chen, Paul Galatsis, Wayne T. Stolle	2005	56
14	Phenobarbital and Phenytoin Increased Acetaminophen Hepatotoxicity Due to Inhibition of UDP-Glucuronosyltransferases in Cultured Human Hepatocytes Toxicological Sciences ·Seva E. Kostrubsky, Jacqueline F. Sinclair, Stephen C. Strom, Sheryl G. Wood, Ellen Urda, Donna B. Stolz, Yuan H. Wen, Shaila Kulkarni, Abdul Mutlib	2005	54
15	Characterization of HKI-272 Covalent Binding to Human Serum Albumin Drug Metabolism and Disposition ·Jianyao Wang, Xiao Xian Li-Chan, Jim Atherton, Linhong Deng, Robert Espina, Linning Yu, Peter Horwatt, Steven M. Ross, Susan Lockhead, Syed Sayeed Ahmad, Appavu Chandrasekaran, Aram Oganesian, JoAnn Scatina, Abdul Mutlib, Rasmy Talaat	2010	51
16	Determination of Degradation Pathways and Kinetics of Acyl Glucuronides by NMR Spectroscopy Chemical Research in Toxicology ·Gregory S. Walker, James Atherton, Jonathan Bauman, Christopher Kohl, Wing Lam, Michael D. Reily, Zhen Lou, Abdul Mutlib	2007	44
17	A Rational Chemical Intervention Strategy To Circumvent Bioactivation Liabilities Associated with a Nonpeptidyl Thrombopoietin Receptor Agonist Containing a 2-Amino-4-arylthiazole Motif Chemical Research in Toxicology ·Amit S. Kalgutkar, James P. Driscoll, Sabrina X. Zhao, Gregory S. Walker, Richard M. Shepard, John R. Soglia, James Atherton, Linning Yu, Abdul Mutlib, Michael J. Munchhof, Lawrence A. Reiter, Christopher S. Jones, Johnathan L. Doty, Kristen A. Trevena, Christopher L. Shaffer, Sharon L. Ripp	2007	38
18	Determination of metoclopramide and two of its metabolites using a sensitive and selective gas chromatographic—mass spectrometric assay Journal of Chromatography B Biomedical Sciences and Applications ·K. Wayne Riggs, András Szeitz, Dan Rurak, Abdul Mutlib, Frank S. Abbott, James E. Axelson	1994	34
19	Picogram determination of iloperidone in human plasma by solid-phase extraction and by high-performance liquid chromatography—selected-ion monitoring electrospray mass spectrometry Journal of Chromatography B Biomedical Sciences and Applications ·Abdul Mutlib, Joseph T. Strupczewski	1995	34
20	Evaluation of absorption, distribution, metabolism, and excretion of [14C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors Investigational New Drugs ·Mingxiang Liao, Simon P. Watkins, Eileen Nash, Jeff Isaacson, Jeff Etter, Jeri Beltman, Rong Fan, Li Shen, Abdul Mutlib, Vendel Kemény, Zsuzsanna Pápai, Pascal van Tilburg, Jim Xiao	2019	29

About Abdul Mutlib

Abdul Mutlib is a scholar working on Pharmacology, Biochemistry, General Energy, Clinical Biochemistry and Toxicology, having authored 61 papers that have together received 2.5k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (19 papers), Drug Transport and Resistance Mechanisms (10 papers), Analytical Chemistry and Chromatography (8 papers), Metabolomics and Mass Spectrometry Studies (8 papers), Drug-Induced Hepatotoxicity and Protection (7 papers), HIV/AIDS drug development and treatment (7 papers), Metabolism and Genetic Disorders (6 papers) and Quinazolinone synthesis and applications (4 papers). The work is most often cited by research in Pharmacology (825 citations), Pharmaceutical Science (176 citations), Pharmacology (388 citations), Spectroscopy (335 citations) and Computational Theory and Mathematics (264 citations). Abdul Mutlib has collaborated with scholars based in United States, Canada and Australia. Frequent co-authors include Robert Espina, Amit S. Kalgutkar, Joseph T. Strupczewski, Christopher L. Shaffer, Yasuhiro Nakai, Jason Boer, Deepak Dalvie, Ernesto Callegari, Kirk R. Henne and Iain Gardner. Their work appears in journals such as Chemical Research in Toxicology, Drug Metabolism and Disposition, Journal of Pharmacology and Experimental Therapeutics, Journal of Mass Spectrometry and Bioorganic & Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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