Sarah C. Sim

3.0k total citations · 1 hit paper
24 papers, 2.1k citations indexed

About

Sarah C. Sim is a scholar working on Pharmacology, Oncology and Pharmacology. According to data from OpenAlex, Sarah C. Sim has authored 24 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Pharmacology, 12 papers in Oncology and 6 papers in Pharmacology. Recurrent topics in Sarah C. Sim's work include Pharmacogenetics and Drug Metabolism (21 papers), Drug Transport and Resistance Mechanisms (9 papers) and Computational Drug Discovery Methods (4 papers). Sarah C. Sim is often cited by papers focused on Pharmacogenetics and Drug Metabolism (21 papers), Drug Transport and Resistance Mechanisms (9 papers) and Computational Drug Discovery Methods (4 papers). Sarah C. Sim collaborates with scholars based in Sweden, United States and Spain. Sarah C. Sim's co-authors include Magnus Ingelman‐Sundberg, Cristina Rodríguez‐Antona, Alvin Gomez, Marina Kacevska, Alan R. Boobis, Robert J. Edwards, Maria Karlgren, Rasmus S. Pedersen, Russ B. Altman and R. Michael Baldwin and has published in prestigious journals such as Biochemical and Biophysical Research Communications, Trends in Pharmacological Sciences and Pharmacology & Therapeutics.

In The Last Decade

Sarah C. Sim

24 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects

2007 859 citations Magnus Ingelman‐Sundberg, Sarah C. Sim et al. Pharmacology & Therapeutics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sarah C. Sim Sweden	20	1.4k	639	496	330	294	24	2.1k
Mats Hidestrand United States	26	876 0.6×	439 0.7×	549 1.1×	183 0.6×	229 0.8×	40	1.8k
Pedro Dorado Spain	26	1.3k 0.9×	464 0.7×	255 0.5×	340 1.0×	335 1.1×	83	1.9k
S. Ball United States	21	1.5k 1.1×	745 1.2×	599 1.2×	295 0.9×	256 0.9×	28	2.3k
Hong‐Guang Xie United States	22	863 0.6×	395 0.6×	626 1.3×	501 1.5×	249 0.8×	40	2.3k
Lydiane Pichard France	18	1.3k 1.0×	808 1.3×	450 0.9×	191 0.6×	323 1.1×	33	2.2k
Su Duan United States	26	1.6k 1.1×	761 1.2×	534 1.1×	458 1.4×	531 1.8×	43	2.9k
Jan van der Weide Netherlands	27	1.6k 1.1×	616 1.0×	553 1.1×	415 1.3×	721 2.5×	47	2.8k
Alvin Gomez Sweden	15	783 0.6×	489 0.8×	660 1.3×	195 0.6×	158 0.5×	18	1.7k
Mikael Oscarson Sweden	29	2.3k 1.6×	977 1.5×	1.3k 2.6×	277 0.8×	369 1.3×	47	3.5k
Thomas Kronbach Switzerland	25	1.6k 1.2×	929 1.5×	677 1.4×	379 1.1×	421 1.4×	37	2.6k

Countries citing papers authored by Sarah C. Sim

Since Specialization

Citations

This map shows the geographic impact of Sarah C. Sim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sarah C. Sim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sarah C. Sim more than expected).

Fields of papers citing papers by Sarah C. Sim

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sarah C. Sim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sarah C. Sim. The network helps show where Sarah C. Sim may publish in the future.

Co-authorship network of co-authors of Sarah C. Sim

This figure shows the co-authorship network connecting the top 25 collaborators of Sarah C. Sim. A scholar is included among the top collaborators of Sarah C. Sim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sarah C. Sim. Sarah C. Sim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sim, Sarah C., et al.. (2018). Pharmacogenetic Impact of Docetaxel on Neoadjuvant Treatment of Breast Cancer Patients. Pharmacogenomics. 19(16). 1259–1268. 15 indexed citations

Jukić, Marin M., Nils Opel, Tania Carrillo‐Roa, et al.. (2016). Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment. Molecular Psychiatry. 22(8). 1155–1163. 39 indexed citations

Chaudhry, Amarjit S., Bhagwat Prasad, Yoshiyuki Shirasaka, et al.. (2015). The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles. Drug Metabolism and Disposition. 43(8). 1226–1235. 25 indexed citations

Sim, Sarah C., et al.. (2013). Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene. Molecular Psychiatry. 19(6). 733–741. 46 indexed citations

Sim, Sarah C. & Magnus Ingelman‐Sundberg. (2013). Update on Allele Nomenclature for Human Cytochromes P450 and the Human Cytochrome P450 Allele (CYP-Allele) Nomenclature Database. Methods in molecular biology. 987. 251–259. 91 indexed citations

Peyrot, Wouter J., Christel M. Middeldorp, Rick Jansen, et al.. (2012). Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample. Journal of Affective Disorders. 146(1). 91–99. 23 indexed citations

Sim, Sarah C., Marina Kacevska, & Magnus Ingelman‐Sundberg. (2012). Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects. The Pharmacogenomics Journal. 13(1). 1–11. 183 indexed citations

Sim, Sarah C., Russ B. Altman, & Magnus Ingelman‐Sundberg. (2011). Databases in the area of pharmacogenetics. Human Mutation. 32(5). 526–531. 37 indexed citations

Ingelman‐Sundberg, Magnus & Sarah C. Sim. (2010). Intronic polymorphisms of cytochromes P450. Human Genomics. 4(6). 402–402. 20 indexed citations

10.

Sim, Sarah C. & Magnus Ingelman‐Sundberg. (2010). Pharmacogenomic biomarkers: new tools in current and future drug therapy. Trends in Pharmacological Sciences. 32(2). 72–81. 65 indexed citations

11.

Ingelman‐Sundberg, Magnus & Sarah C. Sim. (2010). Pharmacogenetic biomarkers as tools for improved drug therapy; emphasis on the cytochrome P450 system. Biochemical and Biophysical Research Communications. 396(1). 90–94. 44 indexed citations

12.

Sim, Sarah C., et al.. (2010). Association between CYP2C19 polymorphism and depressive symptoms. American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 153B(6). 1160–1166. 50 indexed citations

13.

Sim, Sarah C. & Magnus Ingelman‐Sundberg. (2010). The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects. Human Genomics. 4(4). 278–278. 156 indexed citations

14.

Pedersen, Rasmus S., Charlotte Brasch‐Andersen, Sarah C. Sim, et al.. (2010). Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations. European Journal of Clinical Pharmacology. 66(12). 1199–1205. 75 indexed citations

15.

Rodríguez‐Antona, Cristina, Alvin Gomez, Maria Karlgren, Sarah C. Sim, & Magnus Ingelman‐Sundberg. (2009). Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment. Human Genetics. 127(1). 1–17. 89 indexed citations

16.

Baldwin, R. Michael, Masahiro Hiratsuka, Sarah C. Sim, et al.. (2008). Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression. Drug Metabolism and Disposition. 36(5). 955–962. 39 indexed citations

17.

Rosenborg, Staffan, Jessica Mwinyi, Maria Andersson, et al.. (2008). Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects. European Journal of Clinical Pharmacology. 64(12). 1175–1179. 53 indexed citations

18.

Ingelman‐Sundberg, Magnus, Sarah C. Sim, Alvin Gomez, & Cristina Rodríguez‐Antona. (2007). Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacology & Therapeutics. 116(3). 496–526. 859 indexed citations breakdown →

19.

Sim, Sarah C. & Magnus Ingelman‐Sundberg. (2006). The Human Cytochrome P450 Allele Nomenclature Committee Web Site: <i>Submission Criteria, Procedures, and Objectives</i>. Humana Press eBooks. 320. 183–192. 51 indexed citations

20.

Sim, Sarah C., Robert J. Edwards, Alan R. Boobis, & Magnus Ingelman‐Sundberg. (2005). CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele. Pharmacogenetics and Genomics. 15(9). 625–631. 84 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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