Darrin P. Smith

4.2k citations

28 papers · 3.4k · 2 hit papers · h-index 21

Impact in

Developmental Neuroscience top 2%
- Neurogenesis and neuroplasticity mechanisms
Endocrinology, Diabetes and Metabolism top 2%
- Thyroid Cancer Diagnosis and Treatment

Papers in

Molecular Biology 17
- Wnt/β-catenin signaling in development and cancer 4
- RNA Research and Splicing 3
- Retinoids in leukemia and cellular processes 3
Genetics 9
- Estrogen and related hormone effects 3

Co-authors: Bruce A.J. Ponder (9 shared papers)Charis Eng (6 shared papers)M. J. Varas Lorenzo (4 shared papers)Alan Ashworth (2 shared papers)Afshan McCarthy (2 shared papers)Bruce A.J. Ponder (5 shared papers)Carol Houghton (3 shared papers)Kevin A. Green (1 shared paper)
Journals: Oncogene (7 papers)Nucleic Acids Research (3 papers)Nature (2 papers)Development Genes and Evolution (2 papers)Clinical Endocrinology (2 papers)
Partner nations: United Kingdom United States Australia

In The Last Decade

Darrin P. Smith

28 papers receiving 3.3k citations

Darrin P. Smith's Hit Papers

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GDNF signalling through the Ret receptor tyrosine kinase 1996 · 667 citations

Peers

Countries citing papers authored by Darrin P. Smith

Since Specialization

Citations

This map shows the geographic impact of Darrin P. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darrin P. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darrin P. Smith more than expected).

Fields of papers citing papers by Darrin P. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darrin P. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darrin P. Smith. The network helps show where Darrin P. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Darrin P. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Darrin P. Smith Line = papers co-authored together Darrin P. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 28 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Catalytic specificity of protein-tyrosine kinases is critical for selective signalling Nature ·Zhou Songyang, Kermit L. Carraway, Michael J. Eck, Stephen C. Harrison, Ricardo A. Feldman, Moosa Mohammadi, Joseph Schlessinger, Stevan R. Hubbard, Darrin P. Smith, Charis Eng, M. J. Varas Lorenzo, Bruce A.J. Ponder, Bruce J. Mayer, Lewis C. Cantley Hit paper breakdown →	1995	805
2	GDNF signalling through the Ret receptor tyrosine kinase Nature ·Pascale Durbec, Camelia V. Marcos-Gutierrez, Carol Kilkenny, Maria Grigoriou, Kirmo Wartiowaara, Petro Suvanto, Darrin P. Smith, Bruce A.J. Ponder, Frank Costantini, Märt Saarma, Hannu Sariola, Vassilis Pachnis Hit paper breakdown →	1996	667
3	Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction The EMBO Journal ·Kei Sakamoto, Afshan McCarthy, Darrin P. Smith, Kevin A. Green, D. Grahame Hardie, Alan Ashworth, Dario R. Alessi	2005	446
4	Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours Human Molecular Genetics ·Charis Eng, Darrin P. Smith, Lois M. Mulligan, Maria A. Nagal, Catherine S. Healey, Margaret A. Ponder, Emily Gardner, Georg F. W. Scheumann, CharIes E. Jackson, Alan Tunnacllffe, Bruce A.J. Ponder	1994	394
5	Germline mutation of RET codon 883 in two cases of de novo MEN 2B Oncogene ·Darrin P. Smith, Carol Houghton, Bruce A.J. Ponder	1997	134
6	Mutation of the RET protooncogene in sporadic medullary thyroid carcinoma Genes Chromosomes and Cancer ·Charis Eng, Lois M. Mulligan, Darrin P. Smith, Catherine S. Healey, Andrea Frilling, Friedhelm Raue, Hartmut P.H. Neumann, Roswitha Pfragner, A. Behmel, M. J. Varas Lorenzo, Timothy J. Stonehouse, Margaret A. Ponder, Bruce A.J. Ponder	1995	123
7	Low frequency of germline mutations in the RET proto‐oncogene in patients with apparently sporadic medullary thyroid carcinoma Clinical Endocrinology ·Charis Eng, Lois M. Mulligan, Darrin P. Smith, Catherine S. Healey, Andrea Frilling, Friedhelm Raue, Hartmut P.H. Neumann, Margaret A. Ponder, Bruce A.J. Ponder	1995	121
8	RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2 Oncogene ·M. J. Varas Lorenzo, Gerald Gish, Carol Houghton, Timothy J. Stonehouse, Tony Pawson, Bruce A.J. Ponder, Darrin P. Smith	1997	107
9	Regulation of the Wnt signalling component PAR1A by the Peutz–Jeghers syndrome kinase LKB1 Oncogene ·James Spicer, Sydonia Rayter, Neville Young, Richard Elliott, Alan Ashworth, Darrin P. Smith	2003	84
10	Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation Oncogene ·Italia Bongarzone, Elena Viganò, Luisella Alberti, Maria Grazia Borrello, Barbara Pasini, Angela Greco, Piera Mondellini, Darrin P. Smith, Bruce A.J. Ponder, Giovanni Romeo, Marco A. Pierotti	1998	56
11	MYC levels govern hematopoietic tumor type and latency in transgenic mice Blood ·Darrin P. Smith, Mary L. Bath, Donald Metcalf, Alan W. Harris, Suzanne Cory	2006	55
12	The Men II Syndromes and the Role of the ret Proto-oncogene Advances in cancer research ·Bruce A.J. Ponder, Darrin P. Smith	1996	51
13	A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiency Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Sean Sanders, Darrin P. Smith, Geraldine Thomas, E. D. Williams	1997	39
14	C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET Oncogene ·Lucinda F. Reynolds, Ken Jones, Douglas J. Winton, Aaron Cranston, Carol Houghton, Louise Howard, Bruce A.J. Ponder, Darrin P. Smith	2001	39
15	Expression of multiple endocrine neoplasia 2B RET in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behavior in vivo, and activates Jun kinase. PubMed ·Glenn M. Marshall, Anne E. Peaston, Jayne E. Hocker, Stewart A. Smith, Loen M. Hansford, Vivienne Tobias, Murray D. Norris, Michelle Haber, Darrin P. Smith, M. J. Varas Lorenzo, Bruce A.J. Ponder, John F. Hancock	1997	39
16	Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes and Hirschsprung disease Journal of Cell Science ·Darrin P. Smith, Charis Eng, Bruce A.J. Ponder	1994	35
17	T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haemopoietic expression of MYC Oncogene ·Darrin P. Smith, Mary L. Bath, Alan W. Harris, Suzanne Cory	2005	33
18	Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation The Journal of Pathology ·Afshan McCarthy, Christopher J. Lord, Kay Savage, Anita Grigoriadis, Darrin P. Smith, Britta Weigelt, Jorge S. Reis‐Filho, Alan Ashworth	2009	32
19	A novel nuclear receptor superfamily member inXenopusthat associates with RXR, and shares extensive sequence similarity to the mammalian vitamin D3 receptor Nucleic Acids Research ·Darrin P. Smith, Clive Mason, Elizabeth A. Jones, Robert Old	1994	26
20	Post-transcriptional silencing of RET occurs, but is not required, during raf-1 mediated differentiation of medullary thyroid carcinoma cells Oncogene ·Eleanor B. Carson-Walter, Darrin P. Smith, Bruce A.J. Ponder, Stephen B. Baylin, Barry D. Nelkin	1998	25

About Darrin P. Smith

Darrin P. Smith is a scholar working on Molecular Biology, Genetics, Oncology, Epidemiology and Endocrinology, Diabetes and Metabolism, having authored 28 papers that have together received 3.4k indexed citations. Recurring topics across this work include Neuroendocrine Tumor Research Advances (6 papers), Thyroid Cancer Diagnosis and Treatment (5 papers), Wnt/β-catenin signaling in development and cancer (4 papers), RNA Research and Splicing (3 papers), Retinoids in leukemia and cellular processes (3 papers), Cancer-related Molecular Pathways (3 papers), Congenital gastrointestinal and neural anomalies (3 papers) and Estrogen and related hormone effects (3 papers). The work is most often cited by research in Developmental Neuroscience (260 citations), Endocrinology, Diabetes and Metabolism (733 citations), Molecular Biology (2.1k citations), Cellular and Molecular Neuroscience (451 citations) and Oncology (633 citations). Darrin P. Smith has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Bruce A.J. Ponder, Charis Eng, M. J. Varas Lorenzo, Alan Ashworth, Afshan McCarthy, Bruce A.J. Ponder, Carol Houghton, Kevin A. Green, Dario R. Alessi and D. Grahame Hardie. Their work appears in journals such as Oncogene, Nucleic Acids Research, Nature, Development Genes and Evolution and Clinical Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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