John F. Hancock

27.4k total citations · 7 hit papers
210 papers, 21.6k citations indexed

About

John F. Hancock is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, John F. Hancock has authored 210 papers receiving a total of 21.6k indexed citations (citations by other indexed papers that have themselves been cited), including 181 papers in Molecular Biology, 100 papers in Cell Biology and 30 papers in Physiology. Recurrent topics in John F. Hancock's work include Protein Kinase Regulation and GTPase Signaling (93 papers), Cellular transport and secretion (51 papers) and Lipid Membrane Structure and Behavior (37 papers). John F. Hancock is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (93 papers), Cellular transport and secretion (51 papers) and Lipid Membrane Structure and Behavior (37 papers). John F. Hancock collaborates with scholars based in United States, Australia and United Kingdom. John F. Hancock's co-authors include Robert G. Parton, Ian A. Prior, Anthony I. Magee, Hugh Paterson, Christopher J. Marshall, Yong Zhou, Karen A. Cadwallader, Sarah J. Plowman, Christopher J. Marshall and Alemayehu A. Gorfe and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

John F. Hancock

208 papers receiving 21.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 1.6k citations John F. Hancock et al. profile →
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1990 888 citations John F. Hancock et al. profile →
Activation of Raf as a Result of Recruitment to the Plasma Membrane

1994 837 citations John F. Hancock et al. profile →
Ras proteins: different signals from different locations

2003 697 citations John F. Hancock profile →
Lipid rafts: contentious only from simplistic standpoints

2006 671 citations John F. Hancock profile →
Direct visualization of Ras proteins in spatially distinct cell surface microdomains

2003 603 citations Robert G. Parton, John F. Hancock et al. The Journal of Cell Biology profile →
PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function

2008 570 citations Michelle M. Hill, Michele Bastiani et al. profile →

Peers

Countries citing papers authored by John F. Hancock

Since Specialization

Citations

This map shows the geographic impact of John F. Hancock's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John F. Hancock with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John F. Hancock more than expected).

Fields of papers citing papers by John F. Hancock

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John F. Hancock. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John F. Hancock. The network helps show where John F. Hancock may publish in the future.

Co-authorship network of co-authors of John F. Hancock

This figure shows the co-authorship network connecting the top 25 collaborators of John F. Hancock. A scholar is included among the top collaborators of John F. Hancock based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John F. Hancock. John F. Hancock is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids 2024 ·The Journal of Cell Biology ·(unknown), Ali Naji, Ransome van der Hoeven, (unknown), Yong Zhou, Gerald Hammond, John F. Hancock, Kwang‐Jin Cho	1
2	RAS nanoclusters are cell surface transducers that convert extracellular stimuli to intracellular signalling 2023 ·FEBS Letters ·Yong Zhou, John F. Hancock	11
3	Direct Modulators of K-Ras–Membrane Interactions 2023 ·ACS Chemical Biology ·Johannes Morstein, (unknown), Que N. Van, César A. López, (unknown), Marco Tonelli, Liang Hong, De Chen, Yong Zhou, John F. Hancock, Andrew G. Stephen, Thomas J. Turbyville, Kevan M. Shokat	14
4	Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors 2021 ·European Journal of Medicinal Chemistry ·Pingyuan Wang, Dharini van der Hoeven, Na Ye, Haiying Chen, Zhiqing Liu, Xiaoping Ma, Dina Montufar‐Solis, (unknown), Kwang‐Jin Cho, (unknown), Wei Chen, Ransome van der Hoeven, Jeffrey A. Frost, John F. Hancock, Jia Zhou	8
5	Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae 2020 ·The Journal of Cell Biology ·Yong Zhou, Nicholas Ariotti, James Rae, Liang Hong, Vikas A. Tillu, (unknown), Michele Bastiani, Adekunle T. Bademosi, Brett M. Collins, Frédéric A. Meunier, John F. Hancock, Robert G. Parton	43
6	Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function 2019 ·Journal of Cell Science ·(unknown), Kwang‐Jin Cho, Walaa E. Kattan, (unknown), Yong Zhou, (unknown), Robert J. Capon, John F. Hancock	17
7	Targeting plasma membrane phosphatidylserine content to inhibit oncogenic KRAS function 2019 ·Life Science Alliance ·Walaa E. Kattan, Wei Chen, Xiaoping Ma, (unknown), Dharini van der Hoeven, Ransome van der Hoeven, John F. Hancock	30
8	Deciphering lipid codes: K‐Ras as a paradigm 2017 ·Traffic ·Yong Zhou, John F. Hancock	44
9	Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer 2017 ·Molecular Cancer Research ·Lisa Maria Mustachio, Yun Lu, Laura J. Tafe, Vincent A. Memoli, Jaime Rodriguez‐Canales, Barbara Mino, Pamela Villalobos, Ignacio I. Wistuba, Hiroyuki Katayama, Samir Hanash, Jason Roszik, Masanori Kawakami, Kwang-Jin Cho, John F. Hancock, (unknown), Shanhu Hu, Xi Liu, Sarah J. Freemantle, Ethan Dmitrovsky	34
10	Spatiotemporal Analysis of K-Ras Plasma Membrane Interactions Reveals Multiple High Order Homo-oligomeric Complexes 2017 ·Journal of the American Chemical Society ·(unknown), Abdallah Sayyed–Ahmad, Priyanka Prakash, Kwang‐Jin Cho, M. Neal Waxham, John F. Hancock, Alemayehu A. Gorfe	63
11	Sphingomyelin Metabolism Is a Regulator of K-Ras Function 2017 ·Molecular and Cellular Biology ·Dharini van der Hoeven, Kwang‐Jin Cho, Yong Zhou, Xiaoping Ma, Wei Chen, Ali Naji, Dina Montufar‐Solis, Yan Zuo, (unknown), Kandice R. Levental, Jeffrey A. Frost, Ransome van der Hoeven, John F. Hancock	39
12	VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking 2016 ·The Journal of Cell Biology ·Mo Zhou, Heidi H. Wiener, Wenjuan Su, Yong Zhou, Caroline Liot, Ian M. Ahearn, John F. Hancock, Mark R. Philips	43
13	Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling 2014 ·The Journal of Cell Biology ·Nicholas Ariotti, Manuel A. Fernández‐Rojo, Yong Zhou, Michelle M. Hill, Travis L. Rodkey, Kerry L. Inder, Lukas B. Tanner, Markus R. Wenk, John F. Hancock, Robert G. Parton	98
14	Another Surprise from Metformin: Novel Mechanism of Action via K-Ras Influences Endometrial Cancer Response to Therapy 2013 ·Molecular Cancer Therapeutics ·David A. Iglesias, Melinda S. Yates, Dharini van der Hoeven, Travis L. Rodkey, Qian Zhang, Ngai Na Co, Jennifer K. Burzawa, Sravanthi Chigurupati, Joseph Celestino, Jessica L. Bowser, Russell R. Broaddus, John F. Hancock, Rosemarie Schmandt, Karen H. Lu	64
15	The Effects of Transmembrane Sequence and Dimerization on Cleavage of the p75 Neurotrophin Receptor by γ-Secretase 2012 ·Journal of Biological Chemistry ·Alex M. Sykes, (unknown), Daniel Abankwa, Justine M. Hill, Sune Skeldal, Dusan Matusica, (unknown), John F. Hancock, Elizabeth J. Coulson	36
16	Localized Diacylglycerol-dependent Stimulation of Ras and Rap1 during Phagocytosis 2009 ·Journal of Biological Chemistry ·Roberto J. Botelho, Rene E. Harrison, James C. Stone, John F. Hancock, Mark R. Philips, Jenny Jongstra‐Bilen, David Y. Mason, Jonathan Plumb, Michael R. Gold, Sergio Grinstein	30
17	Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles 2005 ·The Journal of Cell Biology ·Matthew Kirkham, Akikazu Fujita, Rahul Chadda, Susan J. Nixon, Teymuras V. Kurzchalia, Deepak Sharma, Richard E. Pagano, John F. Hancock, Satyajit Mayor, Robert G. Parton	341
18	14-3-3 Facilitates Ras-Dependent Raf-1 Activation In Vitro and In Vivo 1998 ·Molecular and Cellular Biology ·Sandrine Roy, R. A. McPherson, Ann Apolloni, Jun Yan, Annette Lane, Jodi Clyde-Smith, John F. Hancock	118
19	[7] Reticulocyte lysate assay for in Vitro translation and posttranslational modification of Ras proteins 1995 ·Methods in enzymology on CD-ROM/Methods in enzymology ·John F. Hancock	21
20	GEO volume 91 issue 3 Cover and Front matter 1954 ·Geological Magazine ·O. M. B. Bulman, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), John F. Hancock, (unknown), Stephen F. Austin, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown)	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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