Charis Eng

74.4k total citations · 16 hit papers
647 papers, 44.8k citations indexed

About

Charis Eng is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Charis Eng has authored 647 papers receiving a total of 44.8k indexed citations (citations by other indexed papers that have themselves been cited), including 376 papers in Molecular Biology, 124 papers in Oncology and 124 papers in Genetics. Recurrent topics in Charis Eng's work include PI3K/AKT/mTOR signaling in cancer (217 papers), Genetic factors in colorectal cancer (65 papers) and BRCA gene mutations in cancer (62 papers). Charis Eng is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (217 papers), Genetic factors in colorectal cancer (65 papers) and BRCA gene mutations in cancer (62 papers). Charis Eng collaborates with scholars based in United States, United Kingdom and Germany. Charis Eng's co-authors include Lois M. Mulligan, Kristin Waite, Jessica L. Mester, Patricia L. M. Dahia, Deborah J. Marsh, Hartmut P.H. Neumann, Mohammed S. Orloff, Joanne Ngeow, Catherine S. Healey and Ramon Parsons and has published in prestigious journals such as Nature, New England Journal of Medicine and Cell.

In The Last Decade

Charis Eng

625 papers receiving 43.8k citations

Hit Papers

Germline mutations of the PTEN gene in Cowden disease, an... 1993 2026 2004 2015 1997 1993 2009 2001 1995 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
    1997 1.5k citations Patricia L. M. Dahia, Charis Eng et al. profile →
  2. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
    1993 1.4k citations Charis Eng et al. profile →
  3. Medullary Thyroid Cancer: Management Guidelines of the American Thyroid Association
    2009 853 citations Charis Eng et al. profile →
  4. Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma
    2001 840 citations Patricia L. M. Dahia, Charis Eng et al. profile →
  5. Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
    1995 805 citations Charis Eng et al. profile →
  6. The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis
    1996 778 citations Charis Eng profile →
  7. Essential Role for Nuclear PTEN in Maintaining Chromosomal Integrity
    2007 768 citations Charis Eng et al. profile →
  8. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
    1997 657 citations Charis Eng et al. Proceedings of the National Academy of Sciences profile →
  9. Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
    2005 592 citations Charis Eng et al. Journal of Medical Genetics profile →
  10. Lifetime Cancer Risks in Individuals with GermlinePTENMutations
    2012 586 citations Jessica L. Mester, Mohammed S. Orloff et al. Clinical Cancer Research profile →
  11. PTEN: One Gene, Many Syndromes
    2003 583 citations Charis Eng profile →
  12. The Relationship Between Specific RET Proto-oncogene Mutations and Disease Phenotype in Multiple Endocrine Neoplasia Type 2
    1996 544 citations Charis Eng profile →
  13. Pheochromocytoma and Paraganglioma
    2019 367 citations Charis Eng et al. profile →
  14. Target identification among known drugs by deep learning from heterogeneous networks
    2020 257 citations Yadi Zhou, Charis Eng et al. profile →
  15. Human breast microbiome correlates with prognostic features and immunological signatures in breast cancer
    2021 199 citations Charis Eng et al. profile →
  16. Functional and Taxonomic Dysbiosis of the Gut, Urine, and Semen Microbiomes in Male Infertility
    2021 125 citations Charis Eng et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Charis Eng United States 106 24.0k 9.8k 8.4k 8.3k 7.8k 647 44.8k
Michaël Pollak Canada 103 26.6k 1.1× 15.9k 1.6× 15.3k 1.8× 11.6k 1.4× 4.0k 0.5× 599 46.8k
Hironobu Sasano Japan 87 11.1k 0.5× 8.2k 0.8× 9.4k 1.1× 6.1k 0.7× 7.3k 0.9× 1.2k 36.3k
Stephen B. Baylin United States 131 60.4k 2.5× 16.0k 1.6× 2.2k 0.3× 13.8k 1.7× 5.1k 0.7× 444 77.0k
Kenneth Walsh United States 113 28.3k 1.2× 4.3k 0.4× 2.7k 0.3× 5.3k 0.6× 7.2k 0.9× 462 54.0k
Ronald A. DePinho United States 149 56.0k 2.3× 23.0k 2.4× 2.2k 0.3× 13.7k 1.6× 6.6k 0.9× 417 86.1k
Albert de la Chapelle Finland 103 18.9k 0.8× 12.3k 1.3× 2.2k 0.3× 10.5k 1.3× 3.3k 0.4× 546 43.1k
Eamonn R. Maher United Kingdom 94 19.4k 0.8× 4.0k 0.4× 1.7k 0.2× 11.8k 1.4× 3.9k 0.5× 423 32.5k
David E. Housman United States 104 32.2k 1.3× 9.8k 1.0× 2.1k 0.3× 3.8k 0.5× 3.0k 0.4× 329 47.8k
John Blenis United States 101 39.2k 1.6× 8.2k 0.8× 1.4k 0.2× 5.6k 0.7× 2.9k 0.4× 222 51.9k
Hiroyuki Aburatani Japan 98 24.4k 1.0× 8.4k 0.9× 1.1k 0.1× 7.6k 0.9× 3.6k 0.5× 531 38.1k

Countries citing papers authored by Charis Eng

Since Specialization
Citations

This map shows the geographic impact of Charis Eng's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charis Eng with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charis Eng more than expected).

Fields of papers citing papers by Charis Eng

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charis Eng. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charis Eng. The network helps show where Charis Eng may publish in the future.

Co-authorship network of co-authors of Charis Eng

This figure shows the co-authorship network connecting the top 25 collaborators of Charis Eng. A scholar is included among the top collaborators of Charis Eng based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Charis Eng. Charis Eng is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Johnson, Ken B., N. Lynn Henry, Mei Wei, et al.. (2023). Genetic variations that influence paclitaxel pharmacokinetics and intracellular effects that may contribute to chemotherapy-induced neuropathy: A narrative review. SHILAP Revista de lepidopterología. 4. 1139883–1139883. 4 indexed citations
2.
Hou, Yuan, Yadi Zhou, Lara Jehi, et al.. (2022). Aging‐related cell type‐specific pathophysiologic immune responses that exacerbate disease severity in aged COVID‐19 patients. Aging Cell. 21(2). e13544–e13544. 10 indexed citations
3.
Johnson, Ken B., Bihua Bie, Jennifer Hockings, et al.. (2022). A Multimodal Approach to Discover Biomarkers for Taxane-Induced Peripheral Neuropathy (TIPN): A Study Protocol. Technology in Cancer Research & Treatment. 21. 2213869057–2213869057. 7 indexed citations
4.
Jaini, Ritika, et al.. (2020). Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation. Molecular Autism. 11(1). 43–43. 10 indexed citations
5.
Mutter, George L., Nicolas M. Monte, Donna Neuberg, Alex Ferenczy, & Charis Eng. (2014). Emergence, Involution, and Progression to Carcinoma of Mutant Clones in Normal Endometrial Tissues. Cancer Research. 74(10). 2796–2802. 38 indexed citations
6.
Schmidt, Laura S., Jessica L. Mester, Samuel Peña‐Llopis, et al.. (2013). A Novel Germline Mutation in BAP1 Predisposes to Familial Clear-Cell Renal Cell Carcinoma. Molecular Cancer Research. 11(9). 1061–1071. 113 indexed citations
7.
Wang, Yu, Qi Yu, Xin He, et al.. (2013). Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation. Molecular Cancer Therapeutics. 13(2). 517–527. 26 indexed citations
8.
He, Xin, et al.. (2013). Cowden Syndrome-Related Mutations in PTEN Associate with Enhanced Proteasome Activity. Cancer Research. 73(10). 3029–3040. 20 indexed citations
9.
Ashida, Shingo, Mohammed S. Orloff, Gürkan Bebek, et al.. (2012). Integrated Analysis Reveals Critical Genomic Regions in Prostate Tumor Microenvironment Associated with Clinicopathologic Phenotypes. Clinical Cancer Research. 18(6). 1578–1587. 34 indexed citations
10.
11.
Wang, Hui, Shan K. Naidu, Ravi Rajmohan, et al.. (2010). Allele-specific tumor spectrum in Pten knockin mice. Proceedings of the National Academy of Sciences. 107(11). 5142–5147. 54 indexed citations
12.
Bennett, Kristi L., Todd Romigh, & Charis Eng. (2009). Disruption of Transforming Growth Factor-β Signaling by Five Frequently Methylated Genes Leads to Head and Neck Squamous Cell Carcinoma Pathogenesis. Cancer Research. 69(24). 9301–9305. 26 indexed citations
13.
Crouser, Elliott D., Daniel A. Culver, Kenneth S. Knox, et al.. (2009). Gene Expression Profiling Identifies MMP-12 and ADAMDEC1 as Potential Pathogenic Mediators of Pulmonary Sarcoidosis. American Journal of Respiratory and Critical Care Medicine. 179(10). 929–938. 113 indexed citations
14.
Trimboli, Anthony J., Koichi Fukino, Alain de Bruin, et al.. (2008). Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer. Cancer Research. 68(3). 937–945. 275 indexed citations
15.
Bennett, Kristi L., Björn Hackanson, Laura T. Smith, et al.. (2007). Tumor Suppressor Activity of CCAAT/Enhancer Binding Protein α Is Epigenetically Down-regulated in Head and Neck Squamous Cell Carcinoma. Cancer Research. 67(10). 4657–4664. 74 indexed citations
16.
Eng, Charis. (2007). Robert J Gorlin, DDS, MS (1923–2006): a geneticist for all seasons. Journal of Medical Genetics. 44(7). 478–479. 1 indexed citations
17.
Yan, Pearlly S., Chinnambally Venkataramu, Ashraf E.K. Ibrahim, et al.. (2006). Mapping Geographic Zones of Cancer Risk with Epigenetic Biomarkers in Normal Breast Tissue. Clinical Cancer Research. 12(22). 6626–6636. 153 indexed citations
18.
Weber, Frank, Rosemary E. Teresi, Christoph E. Broelsch, Andrea Frilling, & Charis Eng. (2006). A Limited Set of Human MicroRNA Is Deregulated in Follicular Thyroid Carcinoma. The Journal of Clinical Endocrinology & Metabolism. 91(9). 3584–3591. 237 indexed citations
19.
Fukino, Koichi, Lei Shen, Satoshi Matsumoto, et al.. (2004). Combined Total Genome Loss of Heterozygosity Scan of Breast Cancer Stroma and Epithelium Reveals Multiplicity of Stromal Targets. Cancer Research. 64(20). 7231–7236. 111 indexed citations
20.
Zhou, Xiao-Ping, Heather Hampel, Jennifer Roggenbuck, et al.. (2002). A 39-bp Deletion Polymorphism in PTEN in African American Individuals. Journal of Molecular Diagnostics. 4(2). 114–117. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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