Patrick A. Lewis

21.9k total citations · 2 hit papers
130 papers, 6.2k citations indexed

About

Patrick A. Lewis is a scholar working on Neurology, Molecular Biology and Physiology. According to data from OpenAlex, Patrick A. Lewis has authored 130 papers receiving a total of 6.2k indexed citations (citations by other indexed papers that have themselves been cited), including 61 papers in Neurology, 52 papers in Molecular Biology and 34 papers in Physiology. Recurrent topics in Patrick A. Lewis's work include Parkinson's Disease Mechanisms and Treatments (61 papers), Alzheimer's disease research and treatments (21 papers) and Cellular transport and secretion (16 papers). Patrick A. Lewis is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (61 papers), Alzheimer's disease research and treatments (21 papers) and Cellular transport and secretion (16 papers). Patrick A. Lewis collaborates with scholars based in United Kingdom, United States and Italy. Patrick A. Lewis's co-authors include John Hardy, Mark Cookson, Claudia Manzoni, Elisa Greggio, Alexandra Beilina, Nicholas Wood, Andrew J. Lees, Andrew Singleton, Rina Bandopadhyay and Shushant Jain and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Patrick A. Lewis

122 papers receiving 6.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

2006 591 citations Elisa Greggio, Rina Bandopadhyay et al. profile →
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences

2016 484 citations Claudia Manzoni, Jana Vandrovcová et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Patrick A. Lewis United Kingdom	39	3.4k	2.8k	1.8k	1.4k	964	130	6.2k
Robert Bowser United States	50	3.3k 1.0×	4.0k 1.4×	1.7k 0.9×	1.2k 0.8×	1.0k 1.0×	153	7.8k
Kurt J. De Vos United Kingdom	31	1.9k 0.6×	3.5k 1.2×	1.1k 0.6×	1.2k 0.8×	605 0.6×	45	6.0k
Bingwei Lu United States	48	2.5k 0.7×	4.9k 1.7×	1.7k 0.9×	2.1k 1.5×	694 0.7×	101	8.0k
Lih‐Shen Chin United States	40	1.7k 0.5×	4.0k 1.4×	1.2k 0.7×	2.1k 1.5×	628 0.7×	70	6.7k
Yuzuru Imai Japan	42	3.7k 1.1×	5.2k 1.8×	1.4k 0.8×	2.4k 1.7×	844 0.9×	102	8.9k
Woojin S. Kim Australia	38	1.5k 0.4×	1.9k 0.7×	1.8k 1.0×	712 0.5×	680 0.7×	121	4.7k
Thomas Brännström Sweden	41	2.6k 0.8×	2.1k 0.7×	810 0.4×	1.1k 0.8×	863 0.9×	107	5.6k
Paolo Paganetti Switzerland	37	923 0.3×	4.1k 1.5×	3.1k 1.7×	2.1k 1.5×	787 0.8×	90	7.1k
Fengli Guo United States	33	1.2k 0.3×	2.5k 0.9×	785 0.4×	874 0.6×	286 0.3×	78	4.9k
Duc M. Duong United States	52	902 0.3×	5.5k 1.9×	2.9k 1.6×	1.4k 1.0×	1.3k 1.3×	163	9.0k

Countries citing papers authored by Patrick A. Lewis

Since Specialization

Citations

This map shows the geographic impact of Patrick A. Lewis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick A. Lewis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick A. Lewis more than expected).

Fields of papers citing papers by Patrick A. Lewis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick A. Lewis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick A. Lewis. The network helps show where Patrick A. Lewis may publish in the future.

Co-authorship network of co-authors of Patrick A. Lewis

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick A. Lewis. A scholar is included among the top collaborators of Patrick A. Lewis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick A. Lewis. Patrick A. Lewis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Parfitt, Gustavo Morrone, et al.. (2025). GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis. Science Advances. 11(51). eadv1434–eadv1434. 1 indexed citations

O’Callaghan, Benjamin, et al.. (2024). Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system. Philosophical Transactions of the Royal Society B Biological Sciences. 379(1899). 20220517–20220517. 6 indexed citations

Ermiş, Beyza, et al.. (2023). On the Challenges of Using Black-Box APIs for Toxicity Evaluation in Research. 7595–7609. 10 indexed citations

Herbst, Susanne, et al.. (2023). Leucine-rich repeat kinase 2 at a glance. Journal of Cell Science. 136(17). 8 indexed citations

Lewis, Patrick A., et al.. (2023). Reasoning over Public and Private Data in Retrieval-Based Systems. Transactions of the Association for Computational Linguistics. 11. 902–921. 5 indexed citations

Ermiş, Beyza, et al.. (2023). Goodtriever: Adaptive Toxicity Mitigation with Retrieval-augmented Models. 5108–5125.

Kluss, Jillian H., Alexandra Beilina, Chad D. Williamson, et al.. (2022). Lysosomal positioning regulates Rab10 phosphorylation at LRRK2 ⁺ lysosomes. Proceedings of the National Academy of Sciences. 119(43). e2205492119–e2205492119. 29 indexed citations

Xiromerisiou, Georgia, Thomas Bourinaris, Henry Houlden, et al.. (2021). SORL1 mutation in a Greek family with Parkinson's disease and dementia. Annals of Clinical and Translational Neurology. 8(10). 1961–1969. 4 indexed citations

Härtlová, Anetta, Susanne Herbst, Julien Peltier, et al.. (2018). LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. The EMBO Journal. 37(12). 126 indexed citations

10.

Deutsch, Gail, et al.. (2016). Complete Unique Genome Sequence, Expression Profile, and Salivary Gland Tissue Tropism of the Herpesvirus 7 Homolog in Pigtailed Macaques. Journal of Virology. 90(15). 6657–6674. 12 indexed citations

11.

Manzoni, Claudia, Adamantios Mamais, Dorien A. Roosen, et al.. (2016). mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1. Scientific Reports. 6(1). 35106–35106. 70 indexed citations

12.

Paisán‐Ruíz, Coro, Patrick A. Lewis, & Andrew Singleton. (2013). LRRK2: Cause, Risk, and Mechanism. Journal of Parkinson s Disease. 3(2). 85–103. 110 indexed citations

13.

Patani, Rickie, Patrick A. Lewis, Daniah Trabzuni, et al.. (2012). Investigating the utility of human embryonic stem cell‐derived neurons to model ageing and neurodegenerative disease using whole‐genome gene expression and splicing analysis. Journal of Neurochemistry. 122(4). 738–751. 45 indexed citations

14.

Lewis, Patrick A.. (2012). Assaying the Kinase Activity of LRRK2 <em>in vitro</em>. Journal of Visualized Experiments. 3 indexed citations

15.

Li, Yongchao, Laura B. Dunn, Elisa Greggio, et al.. (2009). The R1441C mutation alters the folding properties of the ROC domain of LRRK2. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1792(12). 1194–1197. 36 indexed citations

16.

Lewis, Patrick A.. (2009). The function of ROCO proteins in health and disease. Biology of the Cell. 101(3). 183–191. 40 indexed citations

17.

Klinghoffer, Richard A., Brian S. Roberts, James Annis, et al.. (2008). An Optimized Lentivirus-Mediated RNAi Screen Reveals Kinase Modulators of Kinesin-5 Inhibitor Sensitivity. Assay and Drug Development Technologies. 6(1). 105–119. 8 indexed citations

18.

Robertson, D. S., et al.. (2007). Proceedings of the 2nd International Symposium on Languages in Biology and Medicine. CEUR Workshop Proceedings. 4 indexed citations

19.

Hoe, Hyang‐Sook, Matthew J. Cooper, Mark P. Burns, et al.. (2007). The Metalloprotease Inhibitor TIMP-3 Regulates Amyloid Precursor Protein and Apolipoprotein E Receptor Proteolysis. Journal of Neuroscience. 27(40). 10895–10905. 61 indexed citations

20.

Lewis, Patrick A., Siân C. Piper, Matthew Baker, et al.. (2001). Expression of BRI–amyloid β peptide fusion proteins: a novel method for specific high-level expression of amyloid β peptides. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1537(1). 58–62. 29 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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