Fred E. Cohen

33.2k total citations · 14 hit papers
181 papers, 26.2k citations indexed

About

Fred E. Cohen is a scholar working on Molecular Biology, Neurology and Nutrition and Dietetics. According to data from OpenAlex, Fred E. Cohen has authored 181 papers receiving a total of 26.2k indexed citations (citations by other indexed papers that have themselves been cited), including 159 papers in Molecular Biology, 41 papers in Neurology and 38 papers in Nutrition and Dietetics. Recurrent topics in Fred E. Cohen's work include Prion Diseases and Protein Misfolding (82 papers), Protein Structure and Dynamics (43 papers) and Neurological diseases and metabolism (41 papers). Fred E. Cohen is often cited by papers focused on Prion Diseases and Protein Misfolding (82 papers), Protein Structure and Dynamics (43 papers) and Neurological diseases and metabolism (41 papers). Fred E. Cohen collaborates with scholars based in United States, United Kingdom and Germany. Fred E. Cohen's co-authors include Stanley B. Prusiner, Stephen J. DeArmond, Roland L. Dunbrack, Darlene Groth, Holger Wille, Giuseppe Legname, Ingrid Mehlhorn, Olivier Lichtarge, Jiri Safar and Henry R. Bourne and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Fred E. Cohen

180 papers receiving 25.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

1993 1.8k citations Ana Serban, Darlene Groth et al. Proceedings of the National Academy of Sciences profile →
Eight prion strains have PrPSc molecules with different conformations

1998 1.0k citations Jiri Safar, Holger Wille et al. profile →
An Evolutionary Trace Method Defines Binding Surfaces Common to Protein Families

1996 977 citations Olivier Lichtarge, Fred E. Cohen et al. Journal of Molecular Biology profile →
Synthetic Mammalian Prions

2004 807 citations Giuseppe Legname, Ilia V. Baskakov et al. Science profile →
Prion Protein Biology

1998 752 citations Stanley B. Prusiner, Stephen J. DeArmond et al. Cell profile →
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

1995 663 citations Michael Scott, Marilyn Torchia et al. Cell profile →
Therapeutic approaches to protein-misfolding diseases

2003 652 citations Fred E. Cohen et al. profile →
Bayesian statistical analysis of protein side‐chain rotamer preferences

1997 640 citations Roland L. Dunbrack, Fred E. Cohen profile →
Improvements in protein secondary structure prediction by an enhanced neural network

1990 587 citations Fred E. Cohen et al. Journal of Molecular Biology profile →
Structure of the recombinant full-length hamster prion protein PrP(29–231): The N terminus is highly flexible

1997 568 citations Fred E. Cohen, Stanley B. Prusiner et al. Proceedings of the National Academy of Sciences profile →
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

1997 426 citations Kiyotoshi Kaneko, Michael Scott et al. Proceedings of the National Academy of Sciences profile →
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

1997 382 citations Kiyotoshi Kaneko, Darlene Groth et al. Proceedings of the National Academy of Sciences profile →
Structural Clues to Prion Replication

1994 364 citations Fred E. Cohen, Keh‐Ming Pan et al. Science profile →
A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform 1 1Edited by M. Yaniv

1997 298 citations David Peretz, Fred E. Cohen et al. Journal of Molecular Biology profile →

Peers

Countries citing papers authored by Fred E. Cohen

Since Specialization

Citations

This map shows the geographic impact of Fred E. Cohen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fred E. Cohen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fred E. Cohen more than expected).

Fields of papers citing papers by Fred E. Cohen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fred E. Cohen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fred E. Cohen. The network helps show where Fred E. Cohen may publish in the future.

Co-authorship network of co-authors of Fred E. Cohen

This figure shows the co-authorship network connecting the top 25 collaborators of Fred E. Cohen. A scholar is included among the top collaborators of Fred E. Cohen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Fred E. Cohen. Fred E. Cohen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	X-Ray Fiber Diffraction Reveals Major Structural Differences Between Brain-Derived Prions and Recombinant Prion Protein Amyloid 2010 ·Biophysical Journal ·Holger Wille, Wen Bian, Michele McDonald, Amy Kendall, David W. Colby, (unknown), Julian Ollesch, (unknown), Fred E. Cohen, Stanley B. Prusiner, Gerald Stubbs	3
2	Synthetic Mammalian Prions breakdown → 2004 ·Science ·Giuseppe Legname, Ilia V. Baskakov, Hoang-Oanh B. Nguyen, Detlev Riesner, Fred E. Cohen, Stephen J. DeArmond, Stanley B. Prusiner	807
3	5 Structural Studies of Prion Proteins 2004 ·Cold Spring Harbor Monograph Archive ·Cédric Govaerts, Holger Wille, (unknown), Stanley B. Prusiner, Fred E. Cohen	9
4	18 Therapeutic Approaches to Prion Diseases 2004 ·Cold Spring Harbor Monograph Archive ·Stanley B. Prusiner, Barnaby C. H. May, Fred E. Cohen	2
5	Structural studies of the scrapie prion protein by electron crystallography 2002 ·Proceedings of the National Academy of Sciences ·Holger Wille, (unknown), Vincent Guénebaut, Surachai Supattapone, Ana Serban, Fred E. Cohen, David A. Agard, Stanley B. Prusiner	324
6	Pathway Complexity of Prion Protein Assembly into Amyloid 2002 ·Journal of Biological Chemistry ·Ilia V. Baskakov, Giuseppe Legname, Michael A. Baldwin, Stanley B. Prusiner, Fred E. Cohen	363
7	Peter A. Kollman (1944–2001) 2001 ·Structure ·Fred E. Cohen	1
8	A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice 2000 ·Journal of Molecular Biology ·Kiyotoshi Kaneko, Haydn L. Ball, Holger Wille, Hong Zhang, Darlene Groth, Marilyn Torchia, Patrick Tremblay, Jiri Safar, Stanley B. Prusiner, Stephen J. DeArmond, Michael A. Baldwin, Fred E. Cohen	114
9	10 Cell Biology of Prions 1999 ·Cold Spring Harbor Monograph Archive ·Stanley B. Prusiner, Peter J. Peters, Kiyotoshi Kaneko, Albert Taraboulos, Vishwanath R. Lingappa, Fred E. Cohen, Stephen J. DeArmond	17
10	Prion Protein of 106 Residues Creates an Artificial Transmission Barrier for Prion Replication in Transgenic Mice 1999 ·Cell ·Surachai Supattapone, Patrick J. Bosque, Tamaki Muramoto, Holger Wille, Claus Aagaard, David Peretz, (unknown), (unknown), Marilyn Torchia, Jiri Safar, Fred E. Cohen, Stephen J. DeArmond, Stanley B. Prusiner, Michael Scott	173
11	Evolutionary, Mechanistic, and Predictive Analyses of the Hydroxymethyldihydropterin Pyrophosphokinase Family of Proteins 1999 ·Biochemical and Biophysical Research Communications ·Dietlind L. Gerloff, Gina Cannarozzi, Marcin P. Joachimiak, Fred E. Cohen, (unknown), Steven A. Benner	3
12	Meeting review: the Second Meeting on the Critical Assessment of Techniques for Protein Structure Prediction (CASP2), Asilomar, California, December 13–16, 1996 1997 ·PubMed ·Roland L. Dunbrack, Dietlind L. Gerloff, Michael J. Bower, Xiaowu Chen, Olivier Lichtarge, Fred E. Cohen	44
13	Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool 1997 ·Journal of Molecular Biology ·Michael J. Bower, Fred E. Cohen, Roland L. Dunbrack	461
14	Folding & Design: introduction to a new journal 1996 ·PubMed ·Alan R. Fersht, Fred E. Cohen	0
15	Multiple Sequence Information for Threading Algorithms 1996 ·Journal of Molecular Biology ·(unknown), Fred E. Cohen	34
16	A Surface of Minimum Area Metric for the Structural Comparison of Proteins 1996 ·Journal of Molecular Biology ·(unknown), Fred E. Cohen	55
17	In Vitro Antimalarial Activity of Chalcones and Their Derivatives 1995 ·Journal of Medicinal Chemistry ·Rongshi Li, George L. Kenyon, Fred E. Cohen, Xiaowu Chen, Baoqing Gong, José N. Domínguez, Eugene A. Davidson, Gary P. Kurzban, Robert E. Miller, Edwin O. Nuzum, Philip J. Rosenthal, James H. McKerrow	333
18	Protein conformational landscapes: Energy minimization and clustering of a long molecular dynamics trajectory 1995 ·Proteins Structure Function and Bioinformatics ·(unknown), Fred E. Cohen	81
19	Structural Clues to Prion Replication breakdown → 1994 ·Science ·Fred E. Cohen, Keh‐Ming Pan, Ziwei Huang, Michael A. Baldwin, Robert J. Fletterick, Stanley B. Prusiner	364
20	Arresting tissue invasion of a parasite by protease inhibitors chosen with the aid of computer modeling 1991 ·Biochemistry ·Fred E. Cohen, Lydia M. Gregoret, Payman Amiri, Ken Aldape, (unknown), James H. McKerrow	52

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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