Daniel Kirchhofer

8.5k total citations · 2 hit papers
116 papers, 6.4k citations indexed

About

Daniel Kirchhofer is a scholar working on Hematology, Molecular Biology and Genetics. According to data from OpenAlex, Daniel Kirchhofer has authored 116 papers receiving a total of 6.4k indexed citations (citations by other indexed papers that have themselves been cited), including 46 papers in Hematology, 42 papers in Molecular Biology and 19 papers in Genetics. Recurrent topics in Daniel Kirchhofer's work include Blood Coagulation and Thrombosis Mechanisms (38 papers), Liver physiology and pathology (17 papers) and Hemophilia Treatment and Research (17 papers). Daniel Kirchhofer is often cited by papers focused on Blood Coagulation and Thrombosis Mechanisms (38 papers), Liver physiology and pathology (17 papers) and Hemophilia Treatment and Research (17 papers). Daniel Kirchhofer collaborates with scholars based in United States, Switzerland and France. Daniel Kirchhofer's co-authors include Charles Eigenbrot, Yale Nemerson, Paul Moran, Michael D. Pierschbacher, Nigel Mackman, Robert A. Lazarus, David W. Banner, Rajkumar Ganesan, Michael T. Lipari and A. D’Arcy and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Daniel Kirchhofer

113 papers receiving 6.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

1996 607 citations David W. Banner, A. D’Arcy et al. profile →
Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis

2019 308 citations Congqing Wu, Wei Lu et al. Immunity profile →

Peers

Countries citing papers authored by Daniel Kirchhofer

Since Specialization

Citations

This map shows the geographic impact of Daniel Kirchhofer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daniel Kirchhofer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daniel Kirchhofer more than expected).

Fields of papers citing papers by Daniel Kirchhofer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniel Kirchhofer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniel Kirchhofer. The network helps show where Daniel Kirchhofer may publish in the future.

Co-authorship network of co-authors of Daniel Kirchhofer

This figure shows the co-authorship network connecting the top 25 collaborators of Daniel Kirchhofer. A scholar is included among the top collaborators of Daniel Kirchhofer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Daniel Kirchhofer. Daniel Kirchhofer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pyroptosis of pulmonary fibroblasts and macrophages through NLRC4 inflammasome leads to acute respiratory failure 2025 ·Cell Reports ·Yan Zhang, Guoying Zhang, (unknown), Ankit Pandeya, (unknown), Samuel Santos Valença, Ling Yang, Jiaqian Qi, (unknown), Congqing Wu, Daniel Kirchhofer, Toshihiko Shiroishi, Fadi T. Khasawneh, Min Tao, Feng Shao, Christopher M. Waters, Yinan Wei, (unknown)	7
2	Hepsin promotes breast tumor growth signaling via the TGFβ‐EGFR axis 2023 ·Molecular Oncology ·(unknown), Pauliina Munne, (unknown), (unknown), Ilida Suleymanova, (unknown), Daniel Kirchhofer, James W. Janetka, (unknown), (unknown), Jeroen Pouwels, Topi A. Tervonen, Juha Klefström	6
3	Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis 2021 ·Cardiovascular Research ·Marco Witkowski, Mario Witkowski, Julian Friebel, Jennifer A. Buffa, Xinmin S. Li, Zeneng Wang, Naseer Sangwan, Lin Li, Joseph A. DiDonato, Caroline Tizian, Arash Haghikia, Daniel Kirchhofer, François Mach, Lorenz Räber, Christian M. Matter, W.H. Wilson Tang, Ulf Landmesser, Thomas F. Lüscher, Ursula Rauch, Stanley L. Hazen	72
4	Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy 2020 ·Proceedings of the National Academy of Sciences ·Irene Tom, Victoria C. Pham, Kenneth J. Katschke, Wěi Li, Wei‐Ching Liang, Johnny Gutierrez, (unknown), Isabel Figueroa, Shadi Toghi Eshghi, Chingwei V. Lee, Jitendra Kanodia, Scott J. Snipas, Guy S. Salvesen, Phillip Lai, Lee Honigberg, Menno van Lookeren Campagne, Daniel Kirchhofer, Amos Baruch, Jennie R. Lill	40
5	Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge 2020 ·Nature Communications ·Henry R. Maun, Rajesh Vij, Benjamin T. Walters, (unknown), Janet Jackman, Ping Wu, Alberto Estevez, Xiaocheng Chen, Yvonne Franke, Michael T. Lipari, Mark S. Dennis, Daniel Kirchhofer, Claudio Ciferri, Kelly M. Loyet, Tangsheng Yi, Charles Eigenbrot, Robert A. Lazarus, James T. Koerber	38
6	An ancient mechanism of arginine-specific substrate cleavage: What's ‘up’ with NSP4? 2019 ·Biochimie ·Andrew P. AhYoung, (unknown), Stefan Gerhardy, Menno van Lookeren Campagne, Daniel Kirchhofer	10
7	Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis breakdown → 2019 ·Immunity ·Congqing Wu, Wei Lu, Yan Zhang, Guoying Zhang, Xuyan Shi, Yohei Hisada, Steven P. Grover, Xinyi Zhang, Lan Li, Binggang Xiang, Jumei Shi, Xiang‐An Li, Alan Daugherty, Susan S. Smyth, Daniel Kirchhofer, Toshihiko Shiroishi, Feng Shao, Nigel Mackman, Yinan Wei, Zhenyu Li	308
8	Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes 2018 ·Nature Communications ·David S. Hewings, Johanna Heideker, P. Taylur, Andrew P. AhYoung, Farid El Oualid, (unknown), (unknown), Daniel Kirchhofer, Bradley Brasher, Thomas H. Pillow, Nataliya Popovych, Till Maurer, Carsten Schwerdtfeger, William F. Forrest, Kebing Yu, John A. Flygare, Matthew Bogyo, Ingrid E. Wertz	71
9	Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid–induced monocyte trafficking 2017 ·Journal of Biological Chemistry ·Sivareddy Kotla, Nikhlesh K. Singh, Daniel Kirchhofer, Gadiparthi N. Rao	3
10	The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody 2015 ·Biochemical Journal ·Claudio Ciferri, Michael T. Lipari, Wei‐Ching Liang, Alberto Estevez, Julie Q. Hang, Scott Stawicki, Yan Wu, Paul Moran, Michael Elliott, Charles Eigenbrot, Kenneth J. Katschke, Menno van Lookeren Campagne, Daniel Kirchhofer	16
11	Procoagulant and proinflammatory effects of red blood cells on lipopolysaccharide‐stimulated monocytes 2015 ·Journal of Thrombosis and Haemostasis ·Bjarne Østerud, Dusten Unruh, Jan Ole Olsen, Daniel Kirchhofer, A. Phillip Owens, Vladimir Y. Bogdanov	11
12	PAR-1 contributes to the innate immune response during viral infection 2013 ·Journal of Clinical Investigation ·Silvio Antoniak, A. Phillip Owens, (unknown), Julie Williams, (unknown), Alice Weithäuser, Patricia A. Sheridan, (unknown), James P. Luyendyk, Denise Esserman, JoAnn Trejo, Daniel Kirchhofer, Burns C. Blaxall, Rafał Pawliński, Melinda A. Beck, Ursula Rauch, Nigel Mackman	110
13	Mutational Tail Loss Is an Evolutionary Mechanism for Liberating Marapsins and Other Type I Serine Proteases from Transmembrane Anchors 2013 ·Journal of Biological Chemistry ·(unknown), Neil N. Trivedi, Wilfred W. Raymond, Rajkumar Ganesan, Daniel Kirchhofer, George M. Verghese, Charles S. Craik, Eric L. Schneider, (unknown), George H. Caughey	5
14	Proteolytic Activation of Pro-Macrophage-Stimulating Protein by Hepsin 2011 ·Molecular Cancer Research ·Rajkumar Ganesan, Ganesh Kolumam, Seh‐Ching Lin, Ming-Hong Xie, Lydia Santell, Thomas D. Wu, Robert A. Lazarus, Amitabha Chaudhuri, Daniel Kirchhofer	55
15	Hepatocyte growth factor activator (HGFA): molecular structure and interactions with HGFA inhibitor‐1 (HAI‐1) 2010 ·FEBS Journal ·Charles Eigenbrot, Rajkumar Ganesan, Daniel Kirchhofer	19
16	Pegylated Kunitz Domain Inhibitor Suppresses Hepsin-Mediated Invasive Tumor Growth and Metastasis 2009 ·Cancer Research ·Wěi Li, Bu-Er Wang, Paul Moran, Terry Lipari, Rajkumar Ganesan, Racquel Corpuz, Mary J. C. Ludlam, Alvin Gogineni, Hartmut Koeppen, Stuart Bunting, Wei‐Qiang Gao, Daniel Kirchhofer	44
17	Hepsin overexpression promotes tumor growth in an orthotopic prostate cancer model 2007 ·Cancer Research ·Wěi Li, Bu-Er Wang, Wei‐Qiang Gao, Alvin Gogineni, Mary J. Cole, Leo Deguzman, Stuart Bunting, Daniel Kirchhofer	1
18	Tissue Expression, Protease Specificity, and Kunitz Domain Functions of Hepatocyte Growth Factor Activator Inhibitor-1B (HAI-1B), a New Splice Variant of HAI-1 2003 ·Journal of Biological Chemistry ·Daniel Kirchhofer, Mark Peek, Wei Li, Jennifer L. Stamos, Charles Eigenbrot, Saloumeh Kadkhodayan, J. Michael Elliott, Racquel Corpuz, Robert A. Lazarus, Paul Moran	88
19	Activation of blood coagulation factor VIIa with cleaved tissue factor extracellular domain and crystallization of the active complex 1995 ·Proteins Structure Function and Bioinformatics ·Daniel Kirchhofer, Arabinda Guha, Yale Nemerson, William H. Konigsberg, Francis Vilbois, (unknown), David W. Banner, A. D’Arcy	20
20	Endothelial cells stimulated with tumor necrosis factor-alpha express varying amounts of tissue factor resulting in inhomogenous fibrin deposition in a native blood flow system. Effects of thrombin inhibitors. 1994 ·Journal of Clinical Investigation ·Daniel Kirchhofer, T. Tschopp, Paul Hadváry, HR Baumgartner	120

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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