Joseph A. DiDonato

34.4k total citations · 13 hit papers
113 papers, 22.7k citations indexed

About

Joseph A. DiDonato is a scholar working on Molecular Biology, Cancer Research and Immunology. According to data from OpenAlex, Joseph A. DiDonato has authored 113 papers receiving a total of 22.7k indexed citations (citations by other indexed papers that have themselves been cited), including 62 papers in Molecular Biology, 36 papers in Cancer Research and 32 papers in Immunology. Recurrent topics in Joseph A. DiDonato's work include NF-κB Signaling Pathways (27 papers), Gut microbiota and health (25 papers) and Diet and metabolism studies (19 papers). Joseph A. DiDonato is often cited by papers focused on NF-κB Signaling Pathways (27 papers), Gut microbiota and health (25 papers) and Diet and metabolism studies (19 papers). Joseph A. DiDonato collaborates with scholars based in United States, United Kingdom and Germany. Joseph A. DiDonato's co-authors include Michael Karin, Frank Mercurio, Stanley L. Hazen, Caridad Rosette, Zeneng Wang, W.H. Wilson Tang, Aldons J. Lusis, Yuping Wu, Xiaoming Fu and Nathalie Auphan‐Anezin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Joseph A. DiDonato

112 papers receiving 22.3k citations

Hit Papers

Gut flora metabolism of phosphatidylch... 1993 2026 2004 2015 2011 1995 1997 2016 2012 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
    2011 4.1k citations Zeneng Wang, Bruce S. Levison et al. Nature profile →
  2. Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
    1995 2.0k citations Joseph A. DiDonato, Caridad Rosette et al. profile →
  3. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    1997 1.9k citations Joseph A. DiDonato, Makio Hayakawa et al. Nature profile →
  4. Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk
    2016 1.4k citations Jennifer A. Buffa, Zeneng Wang et al. profile →
  5. NF‐κB and the link between inflammation and cancer
    2012 1.3k citations Joseph A. DiDonato, Frank Mercurio et al. profile →
  6. Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis
    2015 996 citations Zeneng Wang, Jennifer A. Buffa et al. profile →
  7. Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†
    1996 651 citations Joseph A. DiDonato, Frank Mercurio et al. Molecular and Cellular Biology profile →
  8. An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models
    2008 577 citations Thomas C. Tallant, Joseph A. DiDonato et al. profile →
  9. Protein carbamylation links inflammation, smoking, uremia and atherogenesis
    2007 544 citations Zeneng Wang, Joseph A. DiDonato et al. Nature Medicine profile →
  10. NF-kappa B activation by ultraviolet light not dependent on a nuclear signal
    1993 544 citations Caridad Rosette, Joseph A. DiDonato et al. profile →
  11. A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors
    2020 489 citations Ina Nemet, Prasenjit Prasad Saha et al. profile →
  12. γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L-Carnitine to TMAO
    2014 424 citations Bruce S. Levison, Jennifer A. Buffa et al. profile →
  13. A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
    2024 59 citations Marc Ferrell, Zeneng Wang et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Joseph A. DiDonato United States 56 12.2k 5.7k 5.2k 5.0k 2.4k 113 22.7k
Roy L. Silverstein United States 79 11.7k 1.0× 7.8k 1.4× 3.6k 0.7× 2.9k 0.6× 2.2k 0.9× 209 24.0k
Charles J. Lowenstein United States 67 8.9k 0.7× 4.7k 0.8× 4.5k 0.9× 8.0k 1.6× 1.8k 0.8× 164 24.9k
Robert E. Gerszten United States 71 11.7k 1.0× 2.5k 0.4× 3.4k 0.7× 4.9k 1.0× 2.0k 0.8× 237 22.9k
Guy A. Zimmerman United States 98 10.5k 0.9× 8.6k 1.5× 3.4k 0.6× 3.0k 0.6× 2.5k 1.0× 262 32.6k
Clary B. Clish United States 91 23.3k 1.9× 4.0k 0.7× 8.7k 1.7× 8.6k 1.7× 2.9k 1.2× 384 40.1k
Thomas M. McIntyre United States 89 10.1k 0.8× 5.8k 1.0× 2.7k 0.5× 3.2k 0.6× 1.9k 0.8× 240 26.2k
Ian M. Adcock United Kingdom 100 11.6k 0.9× 8.6k 1.5× 3.9k 0.7× 13.1k 2.6× 3.2k 1.3× 645 36.4k
Klaus Schulze‐Osthoff Germany 95 17.8k 1.5× 7.3k 1.3× 4.3k 0.8× 2.4k 0.5× 4.6k 1.9× 311 29.8k
Makoto Suematsu Japan 77 10.6k 0.9× 3.0k 0.5× 2.2k 0.4× 3.3k 0.6× 1.4k 0.6× 474 22.6k
Jerrold M. Ward United States 88 14.3k 1.2× 5.5k 1.0× 5.6k 1.1× 2.8k 0.6× 7.3k 3.0× 455 34.9k

Countries citing papers authored by Joseph A. DiDonato

Since Specialization
Citations

This map shows the geographic impact of Joseph A. DiDonato's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph A. DiDonato with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph A. DiDonato more than expected).

Fields of papers citing papers by Joseph A. DiDonato

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph A. DiDonato. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph A. DiDonato. The network helps show where Joseph A. DiDonato may publish in the future.

Co-authorship network of co-authors of Joseph A. DiDonato

This figure shows the co-authorship network connecting the top 25 collaborators of Joseph A. DiDonato. A scholar is included among the top collaborators of Joseph A. DiDonato based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joseph A. DiDonato. Joseph A. DiDonato is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Tang, W.H. Wilson, Xinmin S. Li, Marcia C. de Oliveira Otto, et al.. (2024). The Gut Microbial Metabolite Trimethylamine N-oxide, Incident CKD, and Kidney Function Decline. Journal of the American Society of Nephrology. 35(6). 749–760. 21 indexed citations
2.
Ferrell, Marc, Zeneng Wang, James T. Anderson, et al.. (2024). A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Nature Medicine. 30(2). 424–434. 59 indexed citations breakdown →
3.
Saha, Prasenjit Prasad, Valentin Gogonea, Wendy E. Sweet, et al.. (2024). Gut microbe-generated phenylacetylglutamine is an endogenous allosteric modulator of β2-adrenergic receptors. Nature Communications. 15(1). 6696–6696. 13 indexed citations
4.
Tang, W.H. Wilson, Rozenn N. Lemaître, Paul N. Jensen, et al.. (2024). Trimethylamine N -Oxide and Related Gut Microbe-Derived Metabolites and Incident Heart Failure Development in Community-Based Populations. Circulation Heart Failure. 17(8). e011569–e011569. 13 indexed citations
5.
Wang, Zeneng, Yujin Lee, Heidi Lai, et al.. (2022). Dietary Meat, Trimethylamine N-Oxide-Related Metabolites, and Incident Cardiovascular Disease Among Older Adults: The Cardiovascular Health Study. Arteriosclerosis Thrombosis and Vascular Biology. 42(9). e273–e288. 47 indexed citations
6.
Heianza, Yoriko, Wenjie Ma, Joseph A. DiDonato, et al.. (2021). Ten-year changes in plasma L-carnitine levels and risk of coronary heart disease. European Journal of Nutrition. 61(3). 1353–1362. 7 indexed citations
7.
Witkowski, Marco, Mario Witkowski, Julian Friebel, et al.. (2021). Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis. Cardiovascular Research. 118(10). 2367–2384. 72 indexed citations
8.
Lee, Yujin, Ina Nemet, Zeneng Wang, et al.. (2021). Longitudinal Plasma Measures of Trimethylamine N‐Oxide and Risk of Atherosclerotic Cardiovascular Disease Events in Community‐Based Older Adults. Journal of the American Heart Association. 10(17). e020646–e020646. 71 indexed citations
9.
Gogonea, Valentin, Judith Peters, Gary S. Gerstenecker, et al.. (2020). Protein Backbone and Average Particle Dynamics in Reconstituted Discoidal and Spherical HDL Probed by Hydrogen Deuterium Exchange and Elastic Incoherent Neutron Scattering. Biomolecules. 10(1). 121–121. 2 indexed citations
10.
Zamanian-Daryoush, Maryam, Valentin Gogonea, Anthony J. DiDonato, et al.. (2020). Site-specific 5-hydroxytryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high-density lipoprotein biogenesis. Journal of Biological Chemistry. 295(15). 4836–4848. 16 indexed citations
11.
Heianza, Yoriko, Dianjianyi Sun, Xiang Li, et al.. (2018). Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial. Gut. 68(2). 263–270. 144 indexed citations
12.
Iqbal, Asif, Tessa J. Barrett, Lewis Taylor, et al.. (2016). Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo. eLife. 5. 56 indexed citations
13.
Wu, Zhiping, Valentin Gogonea, Xavier Lee, et al.. (2011). The Low Resolution Structure of ApoA1 in Spherical High Density Lipoprotein Revealed by Small Angle Neutron Scattering. Journal of Biological Chemistry. 286(14). 12495–12508. 44 indexed citations
14.
Heresi, Gustavo A., Metin Aytekin, Jennie Newman, Joseph A. DiDonato, & Raed A. Dweik. (2010). Plasma Levels of High-Density Lipoprotein Cholesterol and Outcomes in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. 182(5). 661–668. 93 indexed citations
15.
DiDonato, Joseph A.. (2000). Assaying for IκB Kinase Activity. Methods in enzymology on CD-ROM/Methods in enzymology. 322. 393–400. 19 indexed citations
16.
Jobin, Christian, Asit Panja, Claus Hellerbrand, et al.. (1998). Inhibition of Proinflammatory Molecule Production by Adenovirus-Mediated Expression of a Nuclear Factor κB Super-Repressor in Human Intestinal Epithelial Cells. The Journal of Immunology. 160(1). 410–418. 158 indexed citations
17.
DiDonato, Joseph A., Makio Hayakawa, David M. Rothwarf, Ebrahim Zandi, & Michael Karin. (1997). A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature. 388(6642). 548–554. 1880 indexed citations breakdown →
18.
DiDonato, Joseph A., Fahri Saatcioglu, & Michael Karin. (1996). Molecular Mechanisms of Immunosuppression and Anti-Inflammatory Activities by Glucocorticoids. American Journal of Respiratory and Critical Care Medicine. 154(2_Part_2). S11–S15. 51 indexed citations
19.
DiDonato, Joseph A., Frank Mercurio, & Michael Karin. (1995). Phosphorylation of IκBα Precedes but Is Not Sufficient for Its Dissociation from NF-κB. Molecular and Cellular Biology. 15(3). 1302–1311. 310 indexed citations
20.
Mercurio, Frank, Joseph A. DiDonato, Caridad Rosette, & Michael Karin. (1992). Molecular Cloning and Characterization of a Novel Rel/NF-χB Family Member Displaying Structural and Functional Homology to NF-χB p50/p105. DNA and Cell Biology. 11(7). 523–537. 91 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Roy L. Silverstein Breakdown of academic impact, for papers by Charles J. Lowenstein Breakdown of academic impact, for papers by Robert E. Gerszten Breakdown of academic impact, for papers by Guy A. Zimmerman Breakdown of academic impact, for papers by Clary B. Clish Breakdown of academic impact, for papers by Thomas M. McIntyre Breakdown of academic impact, for papers by Ian M. Adcock Breakdown of academic impact, for papers by Klaus Schulze‐Osthoff Breakdown of academic impact, for papers by Makoto Suematsu Breakdown of academic impact, for papers by Jerrold M. Ward
Rankless by CCL
2026