Colin H. Macphee

8.8k citations

90 papers · 7.1k · 2 hit papers · h-index 41

Impact in

Cancer Research top 1%
- Protease and Inhibitor Mechanisms
Immunology top 2%

Papers in

Surgery 34
- Lipoproteins and Cardiovascular Health 24
Molecular Biology 34
- Protein Kinase Regulation and GTPase Signaling 14
- Peroxisome Proliferator-Activated Receptors 9

Co-authors: Andrew Zalewski (8 shared papers)Lisa Patel (6 shared papers)Stephen A. Smith (12 shared papers)C. Peter Downes (7 shared papers)Keith E. Suckling (11 shared papers)Paul R. Murdock (1 shared paper)Joanna D. Holbrook (1 shared paper)Christopher Plumpton (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Atherosclerosis (7 papers)Arteriosclerosis Thrombosis and Vascular Biology (6 papers)Journal of Biological Chemistry (5 papers)Biochemical Journal (5 papers)
Partner nations: United States United Kingdom China

In The Last Decade

Colin H. Macphee

89 papers receiving 6.9k citations

Colin H. Macphee's Hit Papers

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Resistin is expressed in human macrophages and directly regulated by PPARγ activators 2003 · 781 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2003 Biochemical and Biophysical Research Communications
2000 New England Journal of Medicine

Peers

Countries citing papers authored by Colin H. Macphee

Since Specialization

Citations

This map shows the geographic impact of Colin H. Macphee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Colin H. Macphee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Colin H. Macphee more than expected).

Fields of papers citing papers by Colin H. Macphee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Colin H. Macphee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Colin H. Macphee. The network helps show where Colin H. Macphee may publish in the future.

Co-authors

The 25 scholars most cited alongside Colin H. Macphee, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Colin H. Macphee Line = papers co-authored together Colin H. Macphee links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 90 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Resistin is expressed in human macrophages and directly regulated by PPARγ activators Biochemical and Biophysical Research Communications ·Lisa Patel, Amy C Buckels, Ian J. Kinghorn, Paul R. Murdock, Joanna D. Holbrook, Christopher Plumpton, Colin H. Macphee, Stephen A. Smith Hit paper breakdown →	2003	781
2	Lipoprotein-Associated Phospholipase A₂as an Independent Predictor of Coronary Heart Disease New England Journal of Medicine ·Chris J. Packard, D S O’Reilly, Muriel Caslake, Alex D. McMahon, Ian Ford, Josephine Cooney, Colin H. Macphee, Keith E. Suckling, Medisettivamsi Naga Sai Krishna, Francis E. Wilkinson, Ann Rumley, Gillian Docherty, John D. Burczak, Gordon Lowe Hit paper breakdown →	2000	671
3	Role of Lipoprotein-Associated Phospholipase A ₂ in Atherosclerosis Arteriosclerosis Thrombosis and Vascular Biology ·Andrew Zalewski, Colin H. Macphee	2005	367
4	Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN Current Biology ·Lisa Patel, Ian Pass, Phil Coxon, C. Peter Downes, Stephen A. Smith, Colin H. Macphee	2001	312
5	Pharmacological Activation of Liver X Receptors Promotes Reverse Cholesterol Transport In Vivo Circulation ·Snehal Naik, Xun Wang, Da Silva, Michael Jaye, Colin H. Macphee, Muredach P. Reilly, Jeffrey T. Billheimer, George H. Rothblat, Daniel J. Rader	2005	301
6	Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor Biochemical Journal ·Colin H. Macphee, Kitty Moores, Helen Boyd, Dash Dhanak, Robert J. Ife, Colin A. Leach, David S. Leake, Kevin J. Milliner, Rebecca A. Patterson, Keith E. Suckling, David G. Tew, Deirdre M. B. Hickey	1999	296
7	Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development Nature Medicine ·Robert L. Wilensky, Yi Shi, Emile R. Mohler, Damir Hamamdzic, Mark Burgert, Jun Li, Anthony D. Postle, Robert S. Fenning, James G. Bollinger, Bryan E. Hoffman, Daniel J. Pelchovitz, Jisheng Yang, Rosanna C. Mirabile, Christine L. Webb, LeFeng Zhang, Ping Zhang, Michael H. Gelb, Max Walker, Andrew Zalewski, Colin H. Macphee	2008	294
8	Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease Atherosclerosis ·Muriel Caslake, Chris J. Packard, Keith E. Suckling, Stephen D. Holmes, Paul Chamberlain, Colin H. Macphee	2000	233
9	The Peroxisome Proliferator-activated Receptor δ Promotes Lipid Accumulation in Human Macrophages Journal of Biological Chemistry ·Helen Vosper, Lisa Patel, Tracey L. Graham, Guennadi A. Khoudoli, Alexander J. Hill, Colin H. Macphee, Ivan L. Pinto, Stephen A. Smith, Keith E. Suckling, C. Roland Wolf, (unknown)	2001	231
10	myo‐Inositol metabolites as cellular signals European Journal of Biochemistry ·C. Peter Downes, Colin H. Macphee	1990	203
11	Lipoprotein-Associated Phospholipase A ₂ , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions Arteriosclerosis Thrombosis and Vascular Biology ·Tomi Häkkinen, Jukka Luoma, Mikko Hiltunen, Colin H. Macphee, Kevin J. Milliner, Lisa Patel, Simon Q.J. Rice, David G. Tew, Kari Karkola, Seppo Ylä‐Herttuala	1999	203
12	Purification, Properties, Sequencing, and Cloning of a Lipoprotein-Associated, Serine-Dependent Phospholipase Involved in the Oxidative Modification of Low-Density Lipoproteins Arteriosclerosis Thrombosis and Vascular Biology ·David G. Tew, Christopher Southan, Simon Q.J. Rice, G. M. Lawrence, Haodong Li, Helen Boyd, Kitty Moores, Israel Gloger, Colin H. Macphee	1996	140
13	Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils Journal of Leukocyte Biology ·John R. White, Christina S. Imburgia, Edward Dul, Edward R. Appelbaum, Kevin O’Donnell, Daniel J. O’Shannessy, Mary Brawner, Jim Fornwald, John E. Adamou, Nabil A. Elshourbagy, Kate M. Kaiser, James J. Foley, Dulcie B. Schmidt, Kyung Johanson, Colin H. Macphee, Kitty Moores, Dean E. McNulty, Gilbert Scott, Robert P. Schleimer, Henry M. Sarau	1997	135
14	Phosphorylation results in activation of a cAMP phosphodiesterase in human platelets. Journal of Biological Chemistry ·Colin H. Macphee, David H. Reifsnyder, Thomas A. Moore, Kenneth M. Lerea, Joseph A. Beavo	1988	118
15	Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses Atherosclerosis ·Yi Shi, Ping Zhang, Lifeng Zhang, Hashim Osman, Emile R. Mohler, Colin H. Macphee, Andrew Zalewski, Anthony D. Postle, Robert L. Wilensky	2006	117
16	Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells Molecular and Cellular Biochemistry ·Nambi Aiyar, Jyoti Disa, Zhaohui Ao, Haisong Ju, Sandhya S. Nerurkar, Robert N. Willette, Colin H. Macphee, Douglas G. Johns, Stephen A. Douglas	2006	116
17	Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib Journal of Alzheimer s Disease ·Nimish K. Acharya, Eli C. Levin, Peter Clifford, Min Han, Ryan Tourtellotte, Dean Chamberlain, Michael Pollaro, Nicholas J. Coretti, Mary C. Kosciuk, Eric P. Nagele, Cassandra DeMarshall, Theresa A. Freeman, Yi Shi, Chenbing Guan, Colin H. Macphee, Robert L. Wilensky, Robert G. Nagele	2013	111
18	The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2 Bioorganic & Medicinal Chemistry Letters ·Josie A. Blackie, Jackie C. Bloomer, Murray J. B. Brown, Hung‐Yuan Cheng, Beverley Hammond, Deirdre M. B. Hickey, Robert J. Ife, Colin A. Leach, Vahn A. Lewis, Colin H. Macphee, Kevin J. Milliner, Kitty Moores, Ivan L. Pinto, Stephen A. Smith, Ian Stansfield, Steven J. Stanway, Maxine Taylor, Colin J. Theobald	2003	100
19	Regulation of D‐3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens European Journal of Immunology ·Stephen G. Ward, Steven C. Ley, Colin H. Macphee, Doreen A. Cantrell	1992	98
20	Lipoprotein-associated phospholipase A2 and atherosclerosis Current Opinion in Lipidology ·Robert L. Wilensky, Colin H. Macphee	2009	96

About Colin H. Macphee

Colin H. Macphee is a scholar working on Surgery, Molecular Biology, Immunology, Cancer Research and Oncology, having authored 90 papers that have together received 7.1k indexed citations. Recurring topics across this work include Lipoproteins and Cardiovascular Health (24 papers), Protein Kinase Regulation and GTPase Signaling (14 papers), Adipokines, Inflammation, and Metabolic Diseases (13 papers), Protease and Inhibitor Mechanisms (13 papers), Cell Adhesion Molecules Research (9 papers), Peroxisome Proliferator-Activated Receptors (9 papers), Antioxidant Activity and Oxidative Stress (9 papers) and Chemokine receptors and signaling (8 papers). The work is most often cited by research in Cancer Research (1.4k citations), Immunology (1.2k citations), Endocrinology, Diabetes and Metabolism (944 citations), Biochemistry (334 citations) and Surgery (2.5k citations). Colin H. Macphee has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Andrew Zalewski, Lisa Patel, Stephen A. Smith, C. Peter Downes, Keith E. Suckling, Paul R. Murdock, Joanna D. Holbrook, Christopher Plumpton, Muriel Caslake and Robert L. Wilensky. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Atherosclerosis, Arteriosclerosis Thrombosis and Vascular Biology, Journal of Biological Chemistry and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Colin H. Macphee

Colin H. Macphee's Hit Papers

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Fields of papers citing papers by Colin H. Macphee

All Works

About Colin H. Macphee

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