Steven C. Ley

9.7k total citations · 2 hit papers
83 papers, 8.1k citations indexed

About

Steven C. Ley is a scholar working on Immunology, Molecular Biology and Cancer Research. According to data from OpenAlex, Steven C. Ley has authored 83 papers receiving a total of 8.1k indexed citations (citations by other indexed papers that have themselves been cited), including 58 papers in Immunology, 34 papers in Molecular Biology and 33 papers in Cancer Research. Recurrent topics in Steven C. Ley's work include NF-κB Signaling Pathways (31 papers), Immune Response and Inflammation (25 papers) and T-cell and B-cell Immunology (17 papers). Steven C. Ley is often cited by papers focused on NF-κB Signaling Pathways (31 papers), Immune Response and Inflammation (25 papers) and T-cell and B-cell Immunology (17 papers). Steven C. Ley collaborates with scholars based in United Kingdom, United States and Tanzania. Steven C. Ley's co-authors include J. Simon C. Arthur, Anthony I. Magee, Peter W. Janes, Panagiotis S. Kabouridis, Julia Janzen, Shao‐Cong Sun, Michaël J. Crumpton, Monica Belich, Thorsten Gantke and Srividya Sriskantharajah and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Steven C. Ley

82 papers receiving 7.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mitogen-activated protein kinases in innate immunity

2013 1.4k citations Steven C. Ley et al. profile →
Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

1999 705 citations Peter W. Janes, Steven C. Ley et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Steven C. Ley United Kingdom	45	4.0k	3.9k	1.8k	1.4k	720	83	8.1k
Gottfried Baier Austria	49	3.4k 0.9×	4.2k 1.1×	1.1k 0.6×	1.7k 1.2×	521 0.7×	163	7.9k
Barbara A. Osborne United States	50	3.1k 0.8×	5.4k 1.4×	1.3k 0.7×	2.1k 1.5×	382 0.5×	161	9.7k
S.G. Hymowitz United States	40	3.0k 0.8×	4.7k 1.2×	1.1k 0.6×	1.6k 1.1×	471 0.7×	50	7.6k
Norman N. Iscove Canada	43	3.1k 0.8×	4.5k 1.1×	1.1k 0.6×	1.7k 1.2×	638 0.9×	76	9.1k
Thomas J. Gonda Australia	46	2.5k 0.6×	5.4k 1.4×	1.1k 0.6×	3.0k 2.1×	599 0.8×	125	9.2k
Edgar Serfling Germany	50	4.8k 1.2×	4.8k 1.2×	1.6k 0.9×	1.8k 1.3×	328 0.5×	143	9.5k
Marc Schmidt‐Supprian Germany	44	4.1k 1.0×	3.8k 1.0×	3.2k 1.7×	1.3k 0.9×	351 0.5×	85	8.4k
Jean-Luc Bodmer Switzerland	23	4.3k 1.1×	6.0k 1.5×	2.0k 1.1×	1.5k 1.1×	439 0.6×	31	8.7k
Gwyn T. Williams United Kingdom	41	3.0k 0.8×	6.0k 1.5×	2.7k 1.5×	1.8k 1.3×	339 0.5×	121	10.1k
Ralph C. Budd United States	43	4.1k 1.0×	3.0k 0.8×	734 0.4×	975 0.7×	367 0.5×	116	6.9k

Countries citing papers authored by Steven C. Ley

Since Specialization

Citations

This map shows the geographic impact of Steven C. Ley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven C. Ley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven C. Ley more than expected).

Fields of papers citing papers by Steven C. Ley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven C. Ley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven C. Ley. The network helps show where Steven C. Ley may publish in the future.

Co-authorship network of co-authors of Steven C. Ley

This figure shows the co-authorship network connecting the top 25 collaborators of Steven C. Ley. A scholar is included among the top collaborators of Steven C. Ley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven C. Ley. Steven C. Ley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wan, Li, Steven C. Ley, Sonia Vanina Forcales, et al.. (2024). Bioinformatic analysis of molecular characteristics and oncogenic features of CARD14 in human cancer. Scientific Reports. 14(1). 22972–22972. 1 indexed citations

Pattison, Michael J., Ana Marı́a Risco, Nahum Sonenberg, et al.. (2023). p38γ and p38δ modulate innate immune response by regulating MEF2D activation. eLife. 12. 3 indexed citations

Härtlová, Anetta, Teresa L. M. Thurston, Helen R. Flynn, et al.. (2021). TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria. The EMBO Journal. 40(10). e106188–e106188. 17 indexed citations

Bourbouli, Mara, et al.. (2021). Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis. Cell Reports. 35(8). 109168–109168. 13 indexed citations

Cano, Florencia, et al.. (2018). A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation. The Journal of Experimental Medicine. 215(11). 2737–2747. 18 indexed citations

Kannan, Yashaswini, Jimena Perez-Lloret, Yanda Li, et al.. (2016). TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology. PLoS Pathogens. 12(8). e1005783–e1005783. 19 indexed citations

McNab, Finlay W., Ricardo Rajsbaum, Evangelos Stavropoulos, et al.. (2013). TPL-2–ERK1/2 Signaling Promotes Host Resistance against Intracellular Bacterial Infection by Negative Regulation of Type I IFN Production. The Journal of Immunology. 191(4). 1732–1743. 74 indexed citations

Bi, Yujing, Naiyan Zeng, Estelle Chanudet, et al.. (2011). A20 inactivation in ocular adnexal MALT lymphoma. Haematologica. 97(6). 926–930. 37 indexed citations

Verstrepen, Lynn, Kelly Verhelst, Geert Loo, et al.. (2010). Expression, biological activities and mechanisms of action of A20 (TNFAIP3). Biochemical Pharmacology. 80(12). 2009–2020. 171 indexed citations

10.

Sriskantharajah, Srividya, Monica Belich, Stamatia Papoutsopoulou, et al.. (2008). Proteolysis of NF-κB1 p105 is essential for T cell antigen receptor–induced proliferation. Nature Immunology. 10(1). 38–47. 60 indexed citations

11.

Saraiva, Margarida, Jillian R. Christensen, Alla V. Tsytsykova, et al.. (2005). Identification of a Macrophage-Specific Chromatin Signature in the IL-10 Locus. The Journal of Immunology. 175(2). 1041–1046. 107 indexed citations

12.

Atkinson, Peter G.P., et al.. (2003). Latent Membrane Protein 1 of Epstein-Barr Virus Stimulates Processing of NF-κB2 p100 to p52. Journal of Biological Chemistry. 278(51). 51134–51142. 64 indexed citations

13.

Beinke, Sören, Monica Belich, & Steven C. Ley. (2002). The Death Domain of NF-κB1 p105 Is Essential for Signal-induced p105 Proteolysis. Journal of Biological Chemistry. 277(27). 24162–24168. 35 indexed citations

14.

Janes, Peter W., Steven C. Ley, Anthony I. Magee, & Panagiotis S. Kabouridis. (2000). The role of lipid rafts in T cell antigen receptor (TCR) signalling. Seminars in Immunology. 12(1). 23–34. 376 indexed citations

15.

Kabouridis, Panagiotis S., et al.. (2000). Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes. European Journal of Immunology. 30(3). 954–963. 303 indexed citations

16.

Belich, Monica, Armando Salmerón, Leland H. Johnston, & Steven C. Ley. (1999). TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105. Nature. 397(6717). 363–368. 187 indexed citations

17.

Ley, Steven C., Winston Verbi, Darryl Pappin, et al.. (1994). Tyrosine phosphorylation of α tubulin in human T lymphocytes. European Journal of Immunology. 24(1). 99–106. 49 indexed citations

18.

Boyer, Claude, Steven C. Ley, Adelina A. Davies, & Michaël J. Crumpton. (1993). Comparative analysis of phosphotyrosyl polypeptides in normal and leukemic human T lymphocytes activated via CD3 or CD2. Molecular Immunology. 30(10). 903–910. 2 indexed citations

19.

Blumberg, Richard S., et al.. (1991). Genetic reconstitution of the T cell receptor (TcR) α/β heterodimer restores the association of CD3 ζ₂ with the TcR/CD3 complex. European Journal of Immunology. 21(2). 473–481. 10 indexed citations

20.

Ley, Steven C., Adelina A. Davies, Brian Druker, & Michaël J. Crumpton. (1991). The T cell receptor/CD3 complex and CD2 stimulate the tyrosine phosphorylation of indistinguishable patterns of polypeptides in the human T leukemic cell line Jurkat. European Journal of Immunology. 21(9). 2203–2209. 64 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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