Murray J. B. Brown

4.0k citations

41 papers · 3.2k indexed · 1 hit paper · h-index 28

Co-authors: Alastair D. Reith James Staunton Jesús Cortés Peter F. Leadlay Paul S. Carter Ainsley A. Culbert David G. Smith Gheorghe‐Doru Roiban
Topics: Enzyme Catalysis and Immobilization (8 papers)RNA and protein synthesis mechanisms (7 papers)Microbial Natural Products and Biosynthesis (5 papers)
Cited by: Pharmacology Molecular Biology Organic Chemistry
Journals: Nature Science Journal of Biological Chemistry
Partner nations: United Kingdom United States Ireland

In The Last Decade

Murray J. B. Brown

40 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

2000 771 citations Matthew P. Coghlan, Ainsley A. Culbert et al. Chemistry & Biology profile →

Peers

Countries citing papers authored by Murray J. B. Brown

Since Specialization

Citations

This map shows the geographic impact of Murray J. B. Brown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Murray J. B. Brown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Murray J. B. Brown more than expected).

Fields of papers citing papers by Murray J. B. Brown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Murray J. B. Brown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Murray J. B. Brown. The network helps show where Murray J. B. Brown may publish in the future.

Co-authorship network of co-authors of Murray J. B. Brown

This figure shows the co-authorship network connecting the top 25 collaborators of Murray J. B. Brown. A scholar is included among the top collaborators of Murray J. B. Brown based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Murray J. B. Brown. Murray J. B. Brown is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Engineered Biocatalyst for Enantioselective Hydrazone Reduction 2025 ·Angewandte Chemie International Edition ·(unknown),Fei Zhao,(unknown),J. Domenech,(unknown),Murray J. B. Brown,Gideon Grogan,(unknown),Nicholas J. Turner,Anthony P. Green	0
2	Engineered Biocatalysts for Enantioselective Reductive Aminations of Cyclic Secondary Amines 2023 ·ChemCatChem ·Ashleigh J. Burke,Thomas M. Lister,James R. Marshall,Murray J. B. Brown,Richard Lloyd,Anthony P. Green,Nicholas J. Turner	10
3	Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK 2022 ·Journal of Biological Chemistry ·(unknown),(unknown),(unknown),Courtney M. Schroeder,Trevor D. Littlewood,(unknown),(unknown),Murray J. B. Brown,Claire Crafter,Helen R. Mott,Darerca Owen	6
4	Biocatalysis: A Pharma Perspective 2019 ·Advanced Synthesis & Catalysis ·Joseph P. Adams,Murray J. B. Brown,Alba Díaz‐Rodríguez,Richard C. Lloyd,Gheorghe‐Doru Roiban	169
5	1-Aryl-3,4-dihydroisoquinoline inhibitors of JNK3 2009 ·Bioorganic & Medicinal Chemistry Letters ·J.A. Christopher,Francis Atkinson,B.D. Bax,Murray J. B. Brown,(unknown),Tsu Tshen Chuang,Emma J. Jones,J. Mosley,(unknown)	29
6	The identification of potent and selective imidazole-based inhibitors of B-Raf kinase 2005 ·Bioorganic & Medicinal Chemistry Letters ·Andrew K. Takle,Murray J. B. Brown,Susannah Davies,David K. Dean,(unknown),Alessandra Gaiba,(unknown),Frank D. King,Peter J. Lovell,A. Naylor,Alastair D. Reith,Jon G.A. Steadman,David M. Wilson	170
7	The Structure of MSK1 Reveals a Novel Autoinhibitory Conformation for a Dual Kinase Protein 2004 ·Structure ·Kathrine J. Smith,Paul S. Carter,Angela Bridges,(unknown),Ceri Lewis,Gary Pettman,Andrew Clarke,Murray J. B. Brown,(unknown),Marc G. Wilkinson,B.D. Bax,Alastair D. Reith	41
8	Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors 2003 ·European Journal of Medicinal Chemistry ·Gordon Bruton,Anthony Huxley,Peter J. O’Hanlon,Barry S. Orlek,Drake S. Eggleston,John Eric Humphries,Simon A. Readshaw,Andrew B. West,Stephen Ashman,Murray J. B. Brown,Keith M. Moore,Andrew J. Pope,Karen O’Dwyer,Wenxin Wang	47
9	The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2 2003 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Jackie C. Bloomer,Murray J. B. Brown,Hung‐Yuan Cheng,Beverley Hammond,Deirdre M. B. Hickey,Robert J. Ife,Colin A. Leach,Vahn A. Lewis,Colin H. Macphee,Kevin J. Milliner,Kitty Moores,Ivan L. Pinto,Stephen A. Smith,Ian Stansfield,Steven J. Stanway,Maxine Taylor,Colin J. Theobald	100
10	Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-Positive antibacterial activity 2003 ·Bioorganic & Medicinal Chemistry Letters ·Richard L. Jarvest,John M. Berge,Murray J. B. Brown,Pamela Brown,(unknown),Andrew K. Forrest,C. S. V. HOUGE‐FRYDRYCH,Peter J. O’Hanlon,(unknown),Stephen Rittenhouse,Robert J. Sheppard	32
11	The Structure of Phosphorylated GSK-3β Complexed with a Peptide, FRATtide, that Inhibits β-Catenin Phosphorylation 2001 ·Structure ·B.D. Bax,Paul S. Carter,Ceri Lewis,(unknown),Angela Bridges,Robert D. Tanner,Gary Pettman,(unknown),Ainsley A. Culbert,Murray J. B. Brown,David G. Smith,Alastair D. Reith	172
12	Simple Absorbance-Based Assays for Ultra-High Throughput Screening 2001 ·SLAS DISCOVERY ·(unknown),Murray J. B. Brown,Andrew J. Pope	25
13	Real Experiences of uHTS: A Prototypic 1536-Well Fluorescence Anisotropy-Based uHTS Screen and Application of Well-Level Quality Control Procedures 2001 ·SLAS DISCOVERY ·Sandra Turconi,(unknown),Stephen Ashman,(unknown),David L. Earnshaw,Ryan P. Bingham,Ulrich Haupts,Murray J. B. Brown,Andrew J. Pope	39
14	GSK‐3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and β‐catenin stabilisation without elevation of glycogen synthase activity 2001 ·FEBS Letters ·Ainsley A. Culbert,Murray J. B. Brown,Sheelagh Frame,Thilo Hagen,Darren A.E. Cross,B.D. Bax,Alastair D. Reith	80
15	Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcriptionbreakdown → 2000 ·Chemistry & Biology ·Matthew P. Coghlan,Ainsley A. Culbert,Darren A.E. Cross,Stacey L. Corcoran,John Yates,Neil Pearce,Oliver Rausch,Gregory Murphy,Paul S. Carter,(unknown),David Mills,Murray J. B. Brown,David Haigh,Robert W. Ward,David G. Smith,Kenneth Murray,Alastair D. Reith,Julie C. Holder	771
16	Characterization of Isoleucyl-tRNA Synthetase from Staphylococcus aureus 1998 ·Journal of Biological Chemistry ·Andrew J. Pope,Keith J. M. Moore,Mary McVey,Lucy Mensah,Neil Benson,(unknown),N. J. P. BROOM,Murray J. B. Brown,Peter J. O’Hanlon	49
17	Characterization of Isoleucyl-tRNA Synthetase from Staphylococcus aureus 1998 ·Journal of Biological Chemistry ·Andrew J. Pope,Jacques Lapointe,Lucy Mensah,Neil Benson,Murray J. B. Brown,Keith J. M. Moore	41
18	A hybrid modular polyketide synthase obtained by domain swapping 1996 ·Chemistry & Biology ·Markiyan Oliynyk,Murray J. B. Brown,Jesús Cortés,James Staunton,Peter F. Leadlay	145
19	Polyketide synthesis in vitro on a modular polyketide synthase 1995 ·Chemistry & Biology ·(unknown),Jesús Cortés,Murray J. B. Brown,(unknown),James Staunton,Peter F. Leadlay	69
20	Repositioning of a Domain in a Modular Polyketide Synthase to Promote Specific Chain Cleavage 1995 ·Science ·Jesús Cortés,(unknown),Gareth A. Roberts,Murray J. B. Brown,James Staunton,Peter F. Leadlay	211

About Murray J. B. Brown

Murray J. B. Brown is a scholar working on Molecular Biology, Biophysics and Pharmaceutical Science, having authored 41 papers that have together received 3.2k indexed citations. Recurring topics across this work include Enzyme Catalysis and Immobilization (8 papers), RNA and protein synthesis mechanisms (7 papers) and Microbial Natural Products and Biosynthesis (5 papers). The work is most often cited by research in Pharmacology (585 citations), Molecular Biology (2.2k citations) and Organic Chemistry (879 citations). Murray J. B. Brown has collaborated with scholars based in United Kingdom, United States and Ireland. Frequent co-authors include Alastair D. Reith, James Staunton, Jesús Cortés, Peter F. Leadlay, Paul S. Carter, Ainsley A. Culbert, David G. Smith, Gheorghe‐Doru Roiban, Darren A.E. Cross and Richard C. Lloyd. Their work appears in journals such as Nature, Science and Journal of Biological Chemistry.

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