David S. Leake

8.2k citations

165 papers · 6.8k indexed · 2 hit papers · h-index 40

Impact in

Biochemistry top 0.05%
- Antioxidant Activity and Oxidative Stress
- Phytochemicals and Antioxidant Activities
Nutrition and Dietetics top 0.5%
- Vitamin C and Antioxidants Research

Papers in

Biochemistry 56
- Antioxidant Activity and Oxidative Stress 56
Oral Surgery 21
- Dental Implant Techniques and Outcomes 18

Co-authors: Urs P. Steinbrecher Daniel Steinberg Srinivasan Parthasarathy Joseph L. Witztum Sara M. Rankin J.R.S. Hoult Rebecca A. Patterson Giovanni E. Mann
Journals: Atherosclerosis (18 papers)FEBS Letters (13 papers)Biochemical Society Transactions (10 papers)Free Radical Research (7 papers)Biochemical Journal (7 papers)
Partner nations: United Kingdom United States Italy

In The Last Decade

David S. Leake

160 papers receiving 6.5k citations

Hit Papers

align trajectories log scale

Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages 1990 · 516 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1990 Biochemical Pharmacology
1984 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by David S. Leake

Since Specialization

Citations

This map shows the geographic impact of David S. Leake's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David S. Leake with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David S. Leake more than expected).

Fields of papers citing papers by David S. Leake

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David S. Leake. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David S. Leake. The network helps show where David S. Leake may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David S. Leake, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David S. Leake Line = papers co-authored together David S. Leake links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A moderate reduction in extracellular pH protects macrophages against apoptosis induced by oxidized low density lipoprotein Journal of Lipid Research ·Andrew B. Gerry, David S. Leake	2008	6
2	Aqueous peroxyl radical exposure to THP-1 cells causes glutathione loss followed by protein oxidation and cell death without increased caspase-3 activity Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Jung Min Boo, Andrew B. Gerry, Erin L. Brown, Annisa Firaudhatil Jannah, David S. Leake, Steven P. Gieseg	2007	15
3	A novel method for production of lipid hydroperoxide- or oxysterol-rich low-density lipoprotein Atherosclerosis ·Andrew B. Gerry, Leanne Satchell, David S. Leake	2007	29
4	Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation Atherosclerosis ·郭凌晨, Andrew B. Gerry, W. Putt, Jane L. Roberts, Richard B. Weinberg, Steve E. Humphries, David S. Leake, Philippa J. Talmud	2006	42
5	Saturated fat-induced changes in Sf 60–400 particle composition reduces uptake of LDL by HepG2 cells Journal of Lipid Research ·Kim G. Jackson, Vatsala Maitin, David S. Leake, Parveen Yaqoob, Christine M. Williams	2005	37
6	Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid Journal of Lipid Research ·Rebecca A. Patterson, Elizabeth Horsley, David S. Leake	2003	111
7	Mechanisms by which cysteine can inhibit or promote the oxidation of low density lipoprotein by copper Atherosclerosis ·Rebecca A. Patterson, David Lamb, David S. Leake	2003	28
8	Quantitative immunohistochemical detection of oxidized low density lipoprotein in the rabbit arterial wall Experimental and Molecular Pathology ·Gislane Domingues, David S. Leake, Peter D. Weinberg	1999	4
9	Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions? Atherosclerosis ·David S. Leake	1997	100
10	Transition metal ions within human atherosclerotic lesions can catalyse the oxidation of low density lipoprotein by macrophages FEBS Letters ·David Lamb, Malcolm J. Mitchinson, David S. Leake	1995	71
11	Induction of the antioxidant stress proteins heme oxygenase‐1 and MSP23 by stress agents and oxidised LDL in cultured vascular smooth muscle cells FEBS Letters ·Richard Siow, Tetsuro Ishii, Hideyo Sato, Shigeru Taketani, David S. Leake, J H Sweiry, Jeremy D. Pearson, Shiro Bannai, Giovanni E. Mann	1995	75
12	The effects of free radical scavengers on the oxidation of low-density lipoproteins by macrophages Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism ·Gary M. Wilkins, David S. Leake	1994	8
13	Iron released from transferrin at acidic pH can catalyse the oxidation of low density lipoprotein FEBS Letters ·David Lamb, David S. Leake	1994	52
14	Oxidation of low density lipoprotein by bovine and porcine aortic endothelial cells and porcine endocardial cells in culture Atherosclerosis ·木村勝三郎, Jerry A. Smith, Gary M. Wilkins, David S. Leake	1993	21
15	The interaction between ruptured erythrocytes and low‐density lipoproteins FEBS Letters ·George Paganga, Catherine Rice‐Evans, Catallo Wj, David S. Leake	1992	57
16	The effect of EDTA on the oxidation of low density lipoprotein Atherosclerosis ·D Lamb, David S. Leake	1992	43
17	The Role of Oxidative Modification and Antioxidants in LDL Metabolism and Atherosclerosis Advances in experimental medicine and biology ·Wendy Jessup, Roger T. Dean, Boaz Weiz, Sara M. Rankin, David S. Leake	1990	29
18	Bone Grafting for Cranial Reconstruction Journal of Craniofacial Surgery ·David S. Leake, Mutaz B. Habal, Ronald F. Young, Frank M. Anderson	1990	1
19	The effects of acetylated low‐density lipoproteins on fluid‐phase pinocytosis by macrophages European Journal of Biochemistry ·T. Asha Vijay, David S. Leake	1989	2
20	Parotid gland sialograms in cystic fibrosis The Journal of Pediatrics ·David S. Leake, Kon‐Taik Khaw, Harry Shwachman	1970	1

About David S. Leake

David S. Leake is a scholar working on Biochemistry, Oral Surgery, Surgery, Nutrition and Dietetics and Anatomy, having authored 165 papers that have together received 6.8k indexed citations. Recurring topics across this work include Antioxidant Activity and Oxidative Stress (56 papers), Atherosclerosis and Cardiovascular Diseases (28 papers), Dental Implant Techniques and Outcomes (18 papers), Cholesterol and Lipid Metabolism (16 papers), Lipoproteins and Cardiovascular Health (15 papers), Facial Trauma and Fracture Management (15 papers), Vitamin C and Antioxidants Research (11 papers) and Bone Tissue Engineering Materials (10 papers). The work is most often cited by research in Biochemistry (2.5k citations), Nutrition and Dietetics (1.4k citations), Immunology (1.2k citations), Biochemistry (386 citations) and Clinical Biochemistry (303 citations). David S. Leake has collaborated with scholars based in United Kingdom, United States and Italy. Frequent co-authors include Urs P. Steinbrecher, Daniel Steinberg, Srinivasan Parthasarathy, Joseph L. Witztum, Sara M. Rankin, J.R.S. Hoult, Rebecca A. Patterson, Giovanni E. Mann, David Lamb and Gary M. Wilkins. Their work appears in journals such as Atherosclerosis, FEBS Letters, Biochemical Society Transactions, Free Radical Research and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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