Christopher Lowe

6.6k citations

45 papers · 2.0k indexed · h-index 20

Impact in

Immunology top 5%
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
Genetics top 5%
- Diabetes and associated disorders
- Genetic Associations and Epidemiology

Papers in ⓘ

Pharmaceutical Science 6
- Fluorine in Organic Chemistry 5
Organic Chemistry 18
- Radical Photochemical Reactions 4
- Chemical synthesis and alkaloids 4

Co-authors: Justin J. Rochford (3 shared papers)Stephen O’Rahilly (3 shared papers)John A. Todd (8 shared papers)John C. Vederas (6 shared papers)Neil Walker (4 shared papers)David Clayton (3 shared papers)Jason D. Cooper (3 shared papers)Jack E. Baldwin (5 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (8 papers)Organic & Biomolecular Chemistry (3 papers)Journal of Allergy and Clinical Immunology (2 papers)Journal of Cell Science (2 papers)Tetrahedron Letters (2 papers)
Partner nations: United Kingdom United States Canada

In The Last Decade

Christopher Lowe

42 papers receiving 1.9k citations

Peers

Countries citing papers authored by Christopher Lowe

Since Specialization

Citations

This map shows the geographic impact of Christopher Lowe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher Lowe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher Lowe more than expected).

Fields of papers citing papers by Christopher Lowe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher Lowe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher Lowe. The network helps show where Christopher Lowe may publish in the future.

Co-authors

The 25 scholars most cited alongside Christopher Lowe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher Lowe Line = papers co-authored together Christopher Lowe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 45 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes Nature Genetics ·Christopher Lowe, Jason D. Cooper, Todd M. Brusko, Neil Walker, Deborah J. Smyth, Rebecca Bailey, Kirsi Bourget, Vincent Plagnol, Sarah Field, Mark A. Atkinson, David Clayton, Linda S. Wicker, John A. Todd	2007	307
2	Adipogenesis at a glance Journal of Cell Science ·Christopher Lowe, Stephen O’Rahilly, Justin J. Rochford	2011	298
3	Localization of a Type 1 Diabetes Locus in the IL2RA/CD25 Region by Use of Tag Single-Nucleotide Polymorphisms The American Journal of Human Genetics ·Adrian Vella, Jason D. Cooper, Christopher Lowe, Neil Walker, Sarah Nutland, Barry Widmer, Richard W. Jones, Susan M. Ring, Wendy L. McArdle, Marcus Pembrey, David P. Strachan, David B. Dunger, C.J. Rebecca Twells, David Clayton, John A. Todd	2005	264
4	Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition Nature Communications ·Michael V. Gormally, Thomas S. Dexheimer, Giovanni Marsico, Deborah A. Sanders, Christopher Lowe, Dijana Matak‐Vinković, Sam Michael, Ajit Jadhav, Ganesha Rai, David J. Maloney, Anton Simeonov, Shankar Balasubramanian	2014	168
5	Association of the interleukin‐2 receptor alpha (IL‐2Rα)/CD25 gene region with Graves’ disease using a multilocus test and tag SNPs Clinical Endocrinology ·Stephan Brand, Christopher Lowe, J. M. Heward, Jayne A. Franklyn, Jason D. Cooper, John A. Todd, Stephen Gough	2007	127
6	NATURALLY OCCURRING β-LACTONES: OCCURRENCE, SYNTHESES AND PROPERTIES. A REVIEW Organic Preparations and Procedures International ·Christopher Lowe, John C. Vederas	1995	61
7	A γ-lactam analogue of penems possessing antibacterial activity Tetrahedron Letters ·Jack E. Baldwin, Christopher Lowe, Christopher J. Schofield, Eun Lee	1986	55
8	Peptide Aldehyde Inhibitors of Hepatitis A Virus 3C Proteinase Biochemistry ·Bruce A. Malcolm, Christopher Lowe, Shirley Shechosky, Ryan T. McKay, Chi Ching Yang, Vibhakar J. Shah, Reyna J. Simon, John C. Vederas, Daniel Smith	1995	52
9	Association of IL13 with total IgE: Evidence against an inverse association of atopy and diabetes Journal of Allergy and Clinical Immunology ·Lisa M. Maier, Joanna M. M. Howson, Neil Walker, Gavin P Spickett, Richard W. Jones, Susan M. Ring, Wendy L. McArdle, Christopher Lowe, Rebecca Bailey, Felicity Payne, John A. Todd, David P. Strachan	2006	52
10	Contrasting genetic association of IL2RAwith SLE and ANCA – associated vasculitis BMC Medical Genetics ·Edward J Carr, Menna R. Clatworthy, Christopher Lowe, John A. Todd, Andrew Wong, Timothy J. Vyse, Lavanya Kamesh, Richard A. Watts, Paul Lyons, Kenneth G. C. Smith	2009	47
11	A novel series of potent and selective IKK2 inhibitors Bioorganic & Medicinal Chemistry Letters ·Alistair H.A. Bingham, Richard Davenport, Lewis Gowers, Roland L. Knight, Christopher Lowe, David Owen, David M. Parry, William R. Pitt	2003	43
12	A γ-lactam analogue of the penems possessing antibacterial activity Tetrahedron ·Jack E. Baldwin, Richard T. Freeman, Christopher Lowe, Christopher J. Schofield, Eun Lee	1989	42
13	Synthesis, Stability, and Antimicrobial Activity of (+)-Obafluorin and Related .beta.-Lactone Antibiotics The Journal of Organic Chemistry ·Yi-Hu Pu, Christopher Lowe, Miloslav Sailer, John C. Vederas	1994	41
14	Cost-effective analysis of candidate genes using htSNPs: a staged approach Genes and Immunity ·Christopher Lowe, Jonathan D. Cooper, Juliet Chapman, Bryan J. Barratt, Rebecca C.J. Twells, E A Green, David A. Savage, Cristian Guja, C Ionescu-Tîrgovişte, Eva Tuomilehto‐Wolf, Jaakko Tuomilehto, John A. Todd, David Clayton	2004	40
15	Synthesis and structure–activity relationships of guanine analogues as phosphodiesterase 7 (PDE7) inhibitors Bioorganic & Medicinal Chemistry Letters ·Michael R. Barnes, Nicola Cooper, Richard Davenport, Hazel J. Dyke, Fiona P. Galleway, F Galvin, Lewis Gowers, Alan F. Haughan, Christopher Lowe, Johannes Meissner, John G Montana, Trevor Morgan, C.Louise Picken, Robert J. Watson	2001	39
16	Reactions of a glycidyl radical equivalent with 2-functionalised allyl stannanes Journal of the Chemical Society Chemical Communications ·Jack E. Baldwin, Robert M. Adlington, Christopher Lowe, Ian A. O’Neil, Gillian L. Sanders, Christopher J. Schofield, J. B. Sweeney	1988	39
17	In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone Bioorganic & Medicinal Chemistry ·Tina S. Morris, Sven Frormann, Shirley Shechosky, Christopher Lowe, Manjinder S. Lall, Verena Gauss‐Müller, Robert H. Purcell, Suzanne U. Emerson, John C. Vederas, Bruce A. Malcolm	1997	35
18	Preclinical and translational pharmacokinetics of a novel THIOMAB™ antibody-antibiotic conjugate againstStaphylococcus aureus mAbs ·Rong Deng, Xiaoju Zhou, Dongwei Li, Hao Cai, Siddharth Sukumaran, Montserrat Carrasco‐Triguero, Ola M. Saad, Denise Nazzal, Christopher Lowe, Saroja Ramanujan, Amrita V. Kamath	2019	28
19	Model studies related to the synthesis of fredericamycin A Journal of the Chemical Society Perkin Transactions 1 ·Derrick L. J. Clive, Ahmad Khodabocus, Peter G. Vernon, A. Ga�tan Angoh, Luc Bordeleau, Donald S. Middleton, Christopher Lowe, Dorit Kellner	1991	23
20	Aryl sulfonamides as selective PDE4 inhibitors Bioorganic & Medicinal Chemistry Letters ·John G. Montana, George M. Buckley, Nicola Cooper, Hazel J. Dyke, Lewis Gowers, Joanna P Gregory, Paul G. Hellewell, Hannah J. Kendall, Christopher Lowe, Robert Maxey, Jadwiga M. Miotla, Robert J. Naylor, Karen A. Runcie, B. R. Tuladhar, J.B.H. Warneck	1998	19

About Christopher Lowe

Christopher Lowe is a scholar working on Pharmaceutical Science, Organic Chemistry, Immunology, Cancer Research and Toxicology, having authored 45 papers that have together received 2.0k indexed citations. Recurring topics across this work include Diabetes and associated disorders (6 papers), Phosphodiesterase function and regulation (6 papers), Cytokine Signaling Pathways and Interactions (5 papers), Fluorine in Organic Chemistry (5 papers), Phenothiazines and Benzothiazines Synthesis and Activities (4 papers), Radical Photochemical Reactions (4 papers), NF-κB Signaling Pathways (4 papers) and Chemical synthesis and alkaloids (4 papers). The work is most often cited by research in Immunology (476 citations), Genetics (568 citations), Endocrinology, Diabetes and Metabolism (237 citations), Organic Chemistry (370 citations) and Molecular Biology (727 citations). Christopher Lowe has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Justin J. Rochford, Stephen O’Rahilly, John A. Todd, John C. Vederas, Neil Walker, David Clayton, Jason D. Cooper, Jack E. Baldwin, Christopher J. Schofield and Rebecca Bailey. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Organic & Biomolecular Chemistry, Journal of Allergy and Clinical Immunology, Journal of Cell Science and Tetrahedron Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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