Bruce A. Malcolm

4.3k total citations · 1 hit paper
52 papers, 2.8k citations indexed

About

Bruce A. Malcolm is a scholar working on Molecular Biology, Hepatology and Epidemiology. According to data from OpenAlex, Bruce A. Malcolm has authored 52 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 24 papers in Hepatology and 13 papers in Epidemiology. Recurrent topics in Bruce A. Malcolm's work include Hepatitis C virus research (21 papers), Monoclonal and Polyclonal Antibodies Research (11 papers) and Hepatitis B Virus Studies (10 papers). Bruce A. Malcolm is often cited by papers focused on Hepatitis C virus research (21 papers), Monoclonal and Polyclonal Antibodies Research (11 papers) and Hepatitis B Virus Studies (10 papers). Bruce A. Malcolm collaborates with scholars based in United States, Canada and Belgium. Bruce A. Malcolm's co-authors include Wenyan Wang, Michael N.G. James, Maia M. Chernaia, Jack F. Kirsch, Keith P. Wilson, Wenyan Wang, Marc Allaire, Brian W. Matthews, Brian M. Beyer and Steven Rosenberg and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Bruce A. Malcolm

51 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Two-Stage PCR Protocol Allowing Introduction of Multiple Mutations, Deletions and Insertions Using QuikChange ^TM Site-Directed Mutagenesis

1999 517 citations Bruce A. Malcolm et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Bruce A. Malcolm United States	26	1.5k	665	558	481	367	52	2.8k
Paul R. Caron United States	26	4.0k 2.6×	725 1.1×	431 0.8×	727 1.5×	179 0.5×	40	5.2k
Hannah Alexander United States	30	2.6k 1.7×	157 0.2×	446 0.8×	838 1.7×	474 1.3×	69	4.4k
Zhongguo Chen United States	19	811 0.5×	188 0.3×	401 0.7×	204 0.4×	113 0.3×	26	1.7k
Antonello Pessi Italy	40	2.5k 1.6×	856 1.3×	973 1.7×	1.0k 2.2×	96 0.3×	114	5.1k
Michael G. Cordingley Canada	33	1.5k 1.0×	325 0.5×	385 0.7×	1.0k 2.2×	169 0.5×	56	3.2k
Jean‐Pierre Lavergne France	23	945 0.6×	333 0.5×	187 0.3×	417 0.9×	101 0.3×	88	2.0k
Josephine C. Ferreon United States	24	1.6k 1.1×	628 0.9×	232 0.4×	605 1.3×	82 0.2×	47	2.9k
Roland Montserret France	27	834 0.5×	1.5k 2.2×	342 0.6×	1.2k 2.5×	214 0.6×	53	2.7k
Robert Esnouf United Kingdom	34	3.8k 2.5×	123 0.2×	2.0k 3.6×	636 1.3×	201 0.5×	76	6.7k
D W McCourt United States	28	1.2k 0.8×	1.1k 1.6×	537 1.0×	894 1.9×	147 0.4×	41	3.4k

Countries citing papers authored by Bruce A. Malcolm

Since Specialization

Citations

This map shows the geographic impact of Bruce A. Malcolm's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce A. Malcolm with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce A. Malcolm more than expected).

Fields of papers citing papers by Bruce A. Malcolm

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce A. Malcolm. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce A. Malcolm. The network helps show where Bruce A. Malcolm may publish in the future.

Co-authorship network of co-authors of Bruce A. Malcolm

This figure shows the co-authorship network connecting the top 25 collaborators of Bruce A. Malcolm. A scholar is included among the top collaborators of Bruce A. Malcolm based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bruce A. Malcolm. Bruce A. Malcolm is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Malcolm, Bruce A., et al.. (2018). PrEP-001 prophylactic effect against rhinovirus and influenza virus - RESULTS of 2 randomized trials. Antiviral Research. 153. 70–77. 5 indexed citations

Schneider, Eric L., Gary W. Ashley, Lieve Dillen, et al.. (2015). Half-life extension of the HIV-fusion inhibitor peptide TRI-1144 using a novel linker technology. European Journal of Pharmaceutics and Biopharmaceutics. 93. 254–259. 6 indexed citations

Bénureau, Yann, Lucile Warter, Bruce A. Malcolm, & Annette Martin. (2010). A comparative analysis of the substrate permissiveness of HCV and GBV-B NS3/4A proteases reveals genetic evidence for an interaction with NS4B protein during genome replication. Virology. 406(2). 228–240. 6 indexed citations

Tong, Xiao & Bruce A. Malcolm. (2005). Trans-complementation of HCV replication by non-structural protein 5A. Virus Research. 115(2). 122–130. 24 indexed citations

Yi, MinKyung, Xiao Tong, Angela Skelton, et al.. (2005). Mutations Conferring Resistance to SCH6, a Novel Hepatitis C Virus NS3/4A Protease Inhibitor. Journal of Biological Chemistry. 281(12). 8205–8215. 86 indexed citations

Lu, Zhuomei, Zhizhang Yin, Linda James, et al.. (2004). Development of a Fluorescence Polarization Bead-Based Coupled Assay to Target Different Activity/Conformation States of a Protein Kinase. SLAS DISCOVERY. 9(4). 309–321. 7 indexed citations

Zhou, S., Rong Liu, Bahige M. Baroudy, Bruce A. Malcolm, & Gregory R. Reyes. (2003). The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA. Virology. 310(2). 333–342. 141 indexed citations

Wang, Wenyan & Bruce A. Malcolm. (2002). Two-Stage Polymerase Chain Reaction Protocol Allowing Introduction of Multiple Mutations, Deletions, and Insertions, Using QuikChangeTM Site-Directed Mutagenesis. Humana Press eBooks. 182. 37–43. 122 indexed citations

Zhang, Rumin, Brian M. Beyer, James Durkin, et al.. (1999). A Continuous Spectrophotometric Assay for the Hepatitis C Virus Serine Protease. Analytical Biochemistry. 270(2). 268–275. 71 indexed citations

10.

Howe, A, Robert A. Chase, S. Shane Taremi, et al.. (1999). A novel recombinant single‐chain hepatitis C virus ns3‐ns4a protein with improved helicase activity. Protein Science. 8(6). 1332–1341. 44 indexed citations

11.

Taremi, S. Shane, Brian M. Beyer, M. Maher, et al.. (1998). Construction, expression, and characterization of a novel fully activated recombinant single‐chain hepatitis C virus protease. Protein Science. 7(10). 2143–2149. 100 indexed citations

12.

Dallaire, Paul, et al.. (1997). Construction of Transforming Growth Factor Alpha (TGF-aaa) Phage Library and Identification of High Binders of Epidermal Growth Factor Receptor (EGFR) by Phage Display. The Journal of Biochemistry. 122(4). 686–690. 8 indexed citations

13.

Vainshtein, Inna, Bruce A. Malcolm, Alexey Atrazhev, et al.. (1996). Peptide rescue of an N‐terminal truncation of the stoffel fragment of Taq DNA polymerase. Protein Science. 5(9). 1785–1792. 13 indexed citations

14.

Moyana, Terence, et al.. (1996). Identification of a decapeptide with the binding reactivity for tumor-associated TAG72 antigen from a phage displayed library. Proteins Structure Function and Bioinformatics. 24(3). 352–358. 9 indexed citations

15.

Malcolm, Bruce A.. (1995). The picornaviral 3C proteinases: Cysteine nucleophiles in serine proteinase folds. Protein Science. 4(8). 1439–1445. 52 indexed citations

16.

Masiarz, Frank R. & Bruce A. Malcolm. (1994). [16] Rapid determination of endoprotease specificity using peptide mixtures and Edman degradation analysis. Methods in enzymology on CD-ROM/Methods in enzymology. 241. 302–310. 5 indexed citations

17.

Allaire, Marc, Maia M. Chernaia, Bruce A. Malcolm, & Michael N.G. James. (1994). Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases. Nature. 369(6475). 72–76. 233 indexed citations

18.

Chernaia, Maia M., et al.. (1993). Hepatitis A Virus 3C Proteinase: Some Properties, Crystallization and Preliminary Crystallographic Characterization. Journal of Molecular Biology. 234(3). 890–893. 6 indexed citations

19.

Bouvier, Jacques, Pascal Schneider, & Bruce A. Malcolm. (1993). A Fluorescent Peptide Substrate for the Surface Metalloprotease of Leishmania. Experimental Parasitology. 76(2). 146–155. 9 indexed citations

20.

Jewell, David A., Wiesław Świętnicki, Ben M. Dunn, & Bruce A. Malcolm. (1992). Hepatitis A virus 3C proteinase substrate specificity. Biochemistry. 31(34). 7862–7869. 53 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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