Christoph Sachse

4.4k total citations · 2 hit papers
32 papers, 3.3k citations indexed

About

Christoph Sachse is a scholar working on Molecular Biology, Pharmacology and Oncology. According to data from OpenAlex, Christoph Sachse has authored 32 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 12 papers in Pharmacology and 7 papers in Oncology. Recurrent topics in Christoph Sachse's work include Pharmacogenetics and Drug Metabolism (12 papers), Glutathione Transferases and Polymorphisms (6 papers) and Schizophrenia research and treatment (4 papers). Christoph Sachse is often cited by papers focused on Pharmacogenetics and Drug Metabolism (12 papers), Glutathione Transferases and Polymorphisms (6 papers) and Schizophrenia research and treatment (4 papers). Christoph Sachse collaborates with scholars based in Germany, United States and United Kingdom. Christoph Sachse's co-authors include Ivar Roots, Jürgen Brockmöller, Steffen Bauer, Muthiah Manoharan, Jürgen Soutschek, Ravi Braich, Neelanjan Mukherjee, Eva Gottwein, William H. Majoros and Jen‐Tsan Chi and has published in prestigious journals such as Nature, SHILAP Revista de lepidopterología and Oncogene.

In The Last Decade

Christoph Sachse

30 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

1997 803 citations Christoph Sachse, Jürgen Brockmöller et al. PubMed profile →
Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

1999 579 citations Christoph Sachse, Jürgen Brockmöller et al. British Journal of Clinical Pharmacology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Christoph Sachse Germany	22	1.4k	1.1k	861	586	438	32	3.3k
Rebecca Blanchard United States	19	756 0.5×	677 0.6×	721 0.8×	169 0.3×	231 0.5×	46	2.0k
Gregory D. Jenkins United States	37	356 0.2×	1.9k 1.6×	802 0.9×	543 0.9×	240 0.5×	127	4.6k
Cynthia Ju United States	36	1.6k 1.1×	1.4k 1.2×	631 0.7×	487 0.8×	400 0.9×	80	5.8k
Vita Dolžan Slovenia	33	446 0.3×	1.3k 1.1×	362 0.4×	268 0.5×	168 0.4×	210	3.7k
Mladen V. Tzvetkov Germany	31	740 0.5×	781 0.7×	1.1k 1.3×	96 0.2×	472 1.1×	122	3.3k
Jan Hendrickx Belgium	29	607 0.4×	1.1k 0.9×	428 0.5×	91 0.2×	281 0.6×	79	3.0k
Masuhiro Nishimura Japan	28	879 0.6×	1.0k 0.9×	996 1.2×	209 0.4×	140 0.3×	92	3.4k
Henriette E. Meyer zu Schwabedissen Switzerland	34	568 0.4×	732 0.6×	1.7k 2.0×	166 0.3×	257 0.6×	148	3.7k
Lauri Kangas Finland	31	250 0.2×	919 0.8×	657 0.8×	395 0.7×	265 0.6×	162	3.3k
Francisco Abad‐Santos Spain	31	845 0.6×	527 0.5×	466 0.5×	59 0.1×	390 0.9×	220	3.3k

Countries citing papers authored by Christoph Sachse

Since Specialization

Citations

This map shows the geographic impact of Christoph Sachse's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christoph Sachse with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christoph Sachse more than expected).

Fields of papers citing papers by Christoph Sachse

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christoph Sachse. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christoph Sachse. The network helps show where Christoph Sachse may publish in the future.

Co-authorship network of co-authors of Christoph Sachse

This figure shows the co-authorship network connecting the top 25 collaborators of Christoph Sachse. A scholar is included among the top collaborators of Christoph Sachse based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christoph Sachse. Christoph Sachse is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sachse, Christoph, Susen Burock, Ulrich Keilholz, et al.. (2022). Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis. Oncogene. 41(39). 4446–4458. 18 indexed citations

Erdmann, Gerrit, Denise Treue, Philipp Jurmeister, et al.. (2020). Multiclass cancer classification in fresh frozen and formalin-fixed paraffin-embedded tissue by DigiWest multiplex protein analysis. Laboratory Investigation. 100(10). 1288–1299. 3 indexed citations

Schumacher, Dirk, Geoffroy Andrieux, Karsten Boehnke, et al.. (2019). Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures. PLoS Genetics. 15(3). e1008076–e1008076. 59 indexed citations

Sachse, Christoph, et al.. (2019). Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming. Journal of Molecular Medicine. 97(6). 761–775. 31 indexed citations

Sehm, Tina, et al.. (2009). 19-P002 miR-196 is an essential early-stage regulator of tail regeneration, upstream of key spinal cord patterning events. Mechanisms of Development. 126. S291–S291. 1 indexed citations

Sehm, Tina, et al.. (2009). miR-196 is an essential early-stage regulator of tail regeneration, upstream of key spinal cord patterning events. Developmental Biology. 334(2). 468–480. 75 indexed citations

Puri, Nitin, Xin Wang, Lilia M. Beauchamp, et al.. (2008). LNA(R) incorporated siRNAs exhibit lower off-target effects compared to 2'-OMethoxy in Cell Phenotypic Assays and Microarray Analysis. Nucleic Acids Symposium Series. 52(1). 25–26. 21 indexed citations

Gottwein, Eva, Neelanjan Mukherjee, Christoph Sachse, et al.. (2007). A viral microRNA functions as an orthologue of cellular miR-155. Nature. 450(7172). 1096–1099. 464 indexed citations

Sachse, Christoph, Eberhard Krausz, Michael Hannus, et al.. (2005). High-Throughput RNA Interference Strategies for Target Discovery and Validation by Using Synthetic Short Interfering RNAs: Functional Genomics Investigations of Biological Pathways. Methods in enzymology on CD-ROM/Methods in enzymology. 392. 242–277. 32 indexed citations

10.

Sachse, Christoph & Christophe J. Echeverri. (2004). Oncology studies using siRNA libraries: the dawn of RNAi-based genomics. Oncogene. 23(51). 8384–8391. 42 indexed citations

11.

Turner, Faye, Gillian Smith, Christoph Sachse, et al.. (2004). Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer. International Journal of Cancer. 112(2). 259–264. 57 indexed citations

12.

Sachse, Christoph, Gillian Smith, Tracy Lightfoot, et al.. (2003). Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism. British Journal of Clinical Pharmacology. 55(1). 68–76. 134 indexed citations

13.

Witte, T, Matthias Tenbusch, H. H. Peter, et al.. (2000). IgA and IgG autoantibodies against alpha-fodrin as markers for Sjögren's syndrome. Systemic lupus erythematosus.. PubMed. 27(11). 2617–20. 44 indexed citations

14.

Friedman, David L., B. Michael Silber, Patrice M. Milos, et al.. (2000). CYP2D6 Genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting. PubMed. 2(4). 1–11. 67 indexed citations

15.

Dettling, Michael, Christoph Sachse, B. Müller‐Oerlinghausen, et al.. (2000). Clozapine-induced Agranulocytosis and Hereditary Polymorphisms of Clozapine Metabolizing Enzymes: No Association with Myeloperoxidase and Cytochrome P4502D6. Pharmacopsychiatry. 33(6). 218–220. 31 indexed citations

16.

Dettling, Michael, Christoph Sachse, Jürgen Brockmöller, et al.. (2000). Long-term therapeutic drug monitoring of clozapine and metabolites in psychiatric in- and outpatients. Psychopharmacology. 152(1). 80–86. 38 indexed citations

17.

Sachse, Christoph, Jürgen Brockmöller, Steffen Bauer, & Ivar Roots. (1999). Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. British Journal of Clinical Pharmacology. 47(4). 445–449. 579 indexed citations breakdown →

18.

Cascorbi, Ingolf, et al.. (1998). Polymorphisms in xenobiotic conjugation and disease predisposition. Toxicology Letters. 102-103. 173–183. 53 indexed citations

19.

Sachse, Christoph, Jürgen Brockmöller, Steffen Bauer, & Ivar Roots. (1997). Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.. PubMed. 60(2). 284–95. 803 indexed citations breakdown →

20.

Sachse, Christoph, Jürgen Brockmöller, Steffen Bauer, Torsten Reum, & Ivar Roots. (1996). A rare insertion of T226 in exon 1 of CYP2D6 causes a frameshift and is associated with the poor metabolizer phenotype: CYP2D6*15. Pharmacogenetics. 6(3). 269–272. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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