I Roots

1.6k citations

19 papers · 1.2k indexed · 1 hit paper · h-index 14

Impact in

Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism
- Treatment of Major Depression
Biological Psychiatry top 10%

Papers in ⓘ

Pharmacology 8
- Pharmacogenetics and Drug Metabolism 8
Cancer Research 5
- Carcinogens and Genotoxicity Assessment 5

Co-authors: Ingolf Cascorbi (6 shared papers)Julia Kirchheiner (4 shared papers)Miroslav Bauer (2 shared papers)J. Brockmöller (1 shared paper)Ma‐Li Wong (1 shared paper)Julio Licínio (1 shared paper)Jürgen Brockmöller (4 shared papers)Karl Ludwig Rost (3 shared papers)
Journals: Pharmacopsychiatry (2 papers)Molecular Psychiatry (2 papers)Clinical Pharmacology & Therapeutics (2 papers)Diabetes Obesity and Metabolism (1 paper)Toxicology Letters (1 paper)
Partner nations: Germany United States Sweden

In The Last Decade

I Roots

19 papers receiving 1.2k citations

Hit Papers

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Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response 2004 · 523 citations

Peers

Countries citing papers authored by I Roots

Since Specialization

Citations

This map shows the geographic impact of I Roots's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by I Roots with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites I Roots more than expected).

Fields of papers citing papers by I Roots

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by I Roots. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by I Roots. The network helps show where I Roots may publish in the future.

Co-authors

The 25 scholars most cited alongside I Roots, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with I Roots Line = papers co-authored together I Roots links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response Molecular Psychiatry ·Julia Kirchheiner, Katharina Nickchen, Miroslav Bauer, Ma‐Li Wong, Julio Licínio, I Roots, J. Brockmöller Hit paper breakdown →	2004	523
2	Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer. PubMed ·Ingolf Cascorbi, J Brockmöller, P.M. Mrozikiewicz, Steffen Bauer, R. Loddenkemper, I Roots	1996	109
3	Increase of cytochrome P450IA2 activity by omeprazole: Evidence by the 13C-[N-3-methyl]-caffeine breath test in poor and extensive metabolizers of S-mephenytoin Clinical Pharmacology & Therapeutics ·Karl Ludwig Rost, H. Brösicke, Jürgen Brockmöller, Matthias Scheffler, H Helge, I Roots	1992	106
4	Association of NAT1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with NAT110. PubMed* ·Ingolf Cascorbi, I Roots, J Brockmöller	2001	70
5	Relationship between adverse effects of antipsychotic treatment and dopamine D2 receptor polymorphisms in patients with schizophrenia Molecular Psychiatry ·Rolf Kaiser, P-B Tremblay, F Klufmöller, I Roots, Jürgen Brockmöller	2002	69
6	Pitfalls in N-acetyltransferase 2 genotyping Pharmacogenetics ·Ingolf Cascorbi, I Roots	1999	57
7	Polymorphisms in xenobiotic conjugation and disease predisposition Toxicology Letters ·J Brockmöller, Ingolf Cascorbi, Reinhold Kerb, Christoph Sachse, I Roots	1998	53
8	Individualized Medicine - Implementation of Pharmacogenetic Diagnostics in Antidepressant Drug Treatment of Major Depressive Disorders Pharmacopsychiatry ·Julia Kirchheiner, Leif Bertilsson, Henrik Bruus, Anders Wolff, I Roots, Miroslav Bauer	2003	45
9	Nonlinear Kinetics After High–Dose Omeprazole Caused by Saturation of Genetically Variable Cyp2c19 Hepatology ·Karl Ludwig Rost, I Roots	1996	34
10	N-Acetyltransferase 2 (NAT2) and Glutathione S-Transferase μ (GSTM1) in Bladder-cancer Patients in a Highly Industrialized Area International Journal of Occupational and Environmental Health ·Klaus Golka, Thomas Reckwitz, M. Kempkes, Ingolf Cascorbi, Meinolf Blaszkewicz, Susanne Reich, I Roots, Juergen Soekeland, Harald Schulze, Hermann M. Bolt	1997	32
11	Clozapine-induced Agranulocytosis and Hereditary Polymorphisms of Clozapine Metabolizing Enzymes: No Association with Myeloperoxidase and Cytochrome P4502D6 Pharmacopsychiatry ·Michael Dettling, Christoph Sachse, B. Müller‐Oerlinghausen, I Roots, Jürgen Brockmöller, A. Rolfs, Ingolf Cascorbi	2000	31
12	Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatment. PubMed ·Karl Ludwig Rost, J Brockmöller, Friederike Esdorn, I Roots	1995	31
13	Detection of the GSTM10 allele by long polymerase chain reaction Pharmacogenetics* ·Reinhold Kerb, J rgen Brockm ller, Christoph Sachse, I Roots	1999	21
14	Extremely Long Plasma Half-Life of Amitriptyline in a Woman with the Cytochrome P450IID6 29/29-Kilobase Wild-Type Allele—A Slowly Reversible Interaction with Fluoxetine Therapeutic Drug Monitoring ·Nicola Victoria Müller, Jürgen Brockmöller, I Roots	1991	18
15	Genetic variants of the insulin receptor substrate‐1 are influencing the therapeutic efficacy of oral antidiabetics Diabetes Obesity and Metabolism ·Angela Seeringer, Shailesh P. Parmar, A. Fischer, Bianca Altissimo, Lisa Zondler, Elena R. Lebedeva, Kai Pitterle, I Roots, Julia Kirchheiner	2010	11
16	Acute Poisoning With Bromofosmethyl (Bromophos) Journal of Toxicology Clinical Toxicology ·Claus Köppel, T. Thomsen, Gerhard Heinemeyer, I Roots	1991	5
17	[Genetic causes for the variability of effects and side effects of drugs]. PubMed ·I Roots	1982	5
18	Impact of the CYP2D6 ultra-rapid metabolizer genotype on CIS- and trans-doxepin pharmacokinetics and serotonin concentration in platelets Clinical Pharmacology & Therapeutics ·Julia Kirchheiner, Hanns-Benjamin Henckel, L. Franke, Ingolf Meineke, Ralf Uebelhack, I Roots, J BROCKMOLLER	2005	5
19	Urinary 6 beta-hydroxycortisol and D-glucaric acid excretion rates are not affected by lansoprazole treatment. PubMed ·Rost Kl, Ulrich Mansmann, I Roots	1997	5

About I Roots

I Roots is a scholar working on Pharmacology, Cancer Research, Psychiatry and Mental health, Pharmacology and Biochemistry, having authored 19 papers that have together received 1.2k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (8 papers), Carcinogens and Genotoxicity Assessment (5 papers), Glutathione Transferases and Polymorphisms (3 papers), Polyamine Metabolism and Applications (3 papers), Bipolar Disorder and Treatment (2 papers), Epigenetics and DNA Methylation (2 papers), Schizophrenia research and treatment (2 papers) and Neurotransmitter Receptor Influence on Behavior (2 papers). The work is most often cited by research in Pharmacology (569 citations), Biological Psychiatry (50 citations), Psychiatry and Mental health (246 citations), Pharmacology (185 citations) and Cancer Research (139 citations). I Roots has collaborated with scholars based in Germany, United States and Sweden. Frequent co-authors include Ingolf Cascorbi, Julia Kirchheiner, Miroslav Bauer, J. Brockmöller, Ma‐Li Wong, Julio Licínio, Jürgen Brockmöller, Karl Ludwig Rost, Christoph Sachse and H Helge. Their work appears in journals such as Pharmacopsychiatry, Molecular Psychiatry, Clinical Pharmacology & Therapeutics, Diabetes Obesity and Metabolism and Toxicology Letters.

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