Timothy A. Chan

111.7k citations

243 papers · 22.7k indexed · 16 hit papers · h-index 77

Impact in

Oncology top 0.05%
- Cancer Immunotherapy and Biomarkers
Cancer Research top 0.1%
- Cancer Genomics and Diagnostics

Papers in

Oncology 124
- Cancer Immunotherapy and Biomarkers 69
- Lung Cancer Research Studies 22
Genetics 44
- Glioma Diagnosis and Treatment 44

Co-authors: Jonathan J. Havel Diego Chowell Kenneth W. Kinzler Bert Vogelstein Luc G.T. Morris Nadeem Riaz Sergio A. Quezada Albrecht Stenzinger
Journals: International Journal of Radiation Oncology*Biology*Physics (27 papers)Journal of Clinical Oncology (21 papers)Clinical Cancer Research (13 papers)Oncotarget (9 papers)Cancer Research (8 papers)
Partner nations: United States Germany Canada

In The Last Decade

Timothy A. Chan

229 papers receiving 22.4k citations

Hit Papers

15 papers align trajectories log scale

The hallmarks of cancer immune evasion 2024 · 186 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Cancer Cell
2023 Nature Reviews Clinical Oncology
2021 ESMO Open
2021 Circulation Research
2019 Nature reviews. Cancer
2018 Annals of Oncology
2018 Science Translational Medicine
2017 Science
2017 Nature
2016 JCI Insight
2015 International Journal of Radiation Oncology*Biology*Physics
2012 Science
2012 Nature
1999 Nature
1999 Cell
1998 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Timothy A. Chan

Since Specialization

Citations

This map shows the geographic impact of Timothy A. Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy A. Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy A. Chan more than expected).

Fields of papers citing papers by Timothy A. Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy A. Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy A. Chan. The network helps show where Timothy A. Chan may publish in the future.

Co-authors

The 25 scholars most cited alongside Timothy A. Chan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Timothy A. Chan Line = papers co-authored together Timothy A. Chan links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling Scientific Reports ·Israel Yinon, Martín Neumann, Patrícia M. A. Silva, Jutta Ortiz-Tánchez, Л М Ярышева, Konstandina Isaakidis, Cornelia Schlee, M. Schroeder, Juan José Arboleda-Osorio, Luc G.T. Morris, Timothy A. Chan, Lorenz Bastian, Thomas Burmeister, Stefan Schwartz, Nicola Gökbuget, Liliana H. Mochmann, Claudia D. Baldus	2023	5
2	Clinical Outcomes of Patients with Brain Metastases from Colorectal Cancer Treated with Stereotactic Radiosurgery International Journal of Radiation OncologyBiologyPhysics ·光青山, Jian Li, Hui Yang, Halima Vahdatpoor, Samuel T. Chao, Erin S. Murphy, John H. Suh, Timothy A. Chan, 靳小雨, Gene H. Barnett, Alireza M. Mohammadi, Lilyana Angelov, Glen Stevens, Michael Valente, Scott R. Steele, Emre Görgün, David Liska, Alok A. Khorana, Smitha Krishnamurthi, Ehsan H. Balagamwala	2023	2
3	Aging‐related cell type‐specific pathophysiologic immune responses that exacerbate disease severity in aged COVID‐19 patients Aging Cell ·Yuan Hou, Yadi Zhou, Lara Jehi, Yuan Luo, Michaela U. Gack, Timothy A. Chan, Haiyuan Yu, Charis Eng, Andrew A. Pieper, Feixiong Cheng	2022	10
4	Targeting the mTOR Pathway in Hurthle Cell Carcinoma Results in Potent Antitumor Activity Molecular Cancer Therapeutics ·Yiyu Dong, Yongxing Gong, Fengshen Kuo, Vladimir Makarov, Ed Reznik, Gouri J. Nanjangud, Ömer Aras, HuiYong Zhao, Rui Qu, James A. Fagin, Eric J. Sherman, Bin Xu, Ronald Ghossein, Timothy A. Chan, Ian Ganly	2021	4
5	The Immune Microenvironment and Neoantigen Landscape of Aggressive Salivary Gland Carcinomas Differ by Subtype Clinical Cancer Research ·Maximilian Linxweiler, Fengshen Kuo, Nora Katabi, Mark Lee, Zaineb Nadeem, Martin G. Dalin, Vladimir Makarov, Diego Chowell, Snjezana Doğan, Ian Ganly, A. Ari Hakimi, Richard J. Wong, Nadeem Riaz, Alan L. Ho, Timothy A. Chan, Luc G.T. Morris	2020	79
6	Transcriptomic Profiling of the Tumor Microenvironment Reveals Distinct Subgroups of Clear Cell Renal Cell Cancer: Data from a Randomized Phase III Trial Cancer Discovery ·A. Ari Hakimi, Martin H. Voss, Fengshen Kuo, Alejandro Sánchez, Ming Liu, Briana G. Nixon, Lynda Vuong, Irina Ostrovnaya, Ying‐Bei Chen, Victor E. Reuter, Nadeem Riaz, Yuan Cheng, Parul Patel, Mahtab Marker, Albert Reising, Ming O. Li, Timothy A. Chan, Robert J. Motzer	2019	156
7	ImmunoMap: A Bioinformatics Tool for T-cell Repertoire Analysis Cancer Immunology Research ·John-William Sidhom, Catherine Bessell, Jonathan J. Havel, Alyssa K. Kosmides, Timothy A. Chan, Jonathan P. Schneck	2017	31
8	Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers Clinical Cancer Research ·Erik S. Knudsen, Paris Vail, Uthra Balaji, D Vandeginste, Ihab W. Botros, Vladimir Makarov, Nadeem Riaz, Vinod P. Balachandran, Steven D. Leach, Debrah M. Thompson, Timothy A. Chan, Agnieszka K. Witkiewicz	2017	143
9	Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence Clinical Cancer Research ·Tihana Ibrahimpašić, Bin Xu, Iñigo Landa, Snjezana Doğan, Sumit Middha, Venkatraman Seshan, Zárate C. Luz Clemencia, Diane L. Carlson, Jocelyn Migliacci, Jeffrey A. Knauf, Brian R. Untch, Michael F. Berger, Luc G.T. Morris, R. Michael Tuttle, Timothy A. Chan, James A. Fagin, Ronald Ghossein, Ian Ganly	2017	94
10	Merkel Cell Carcinoma Patients Presenting Without a Primary Lesion Have Elevated Markers of Immunity, Higher Tumor Mutation Burden, and Improved Survival Clinical Cancer Research ·Natalie Vandeven, Christopher W. Lewis, Vladimir Makarov, Nadeem Riaz, Kelly G. Paulson, Daniel S. Hippe, Alejandra Villamil, Ryan Doumani, Lucija Gorički, Teja Indrakanti, Timothy A. Chan, Jaehyuk Choi, Paul Nghiem	2017	43
11	Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells Clinical Cancer Research ·Prajwal Rajappa, William S. Cobb, T.R.Muth, Yujie Huang, Laura Daly, Caitlin Hoffman, Jane Zhang, Beiyi Shen, Josef Pochodzalla, Jessica Tanzil, Babacar Cisse, Sara Haddock, Jason T. Huse, David J. Pisapia, Timothy A. Chan, David Lyden, Jacqueline Bromberg, Jeffrey P. Greenfield	2016	23
12	Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes Cancer Research ·Andriy Marusyk, Doris P. Tabassum, Michalina Janiszewska, Andrew E. Place, Anne Trinh, Andrii I. Rozhok, Saumyadipta Pyne, Jennifer L. Guerriero, Shaokun Shu, Muhammad B. Ekram, Denise Ogilvy, Daniel P. Cahill, Yuri Nikolsky, Timothy A. Chan, Mothaffar F. Rimawi, Susan G. Hilsenbeck, Rachel Schiff, Kent C. Osborne, Antony Letai, Kornélia Polyák	2016	96
13	Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer Clinical Cancer Research ·Martin G. Dalin, Alexis Desrichard, Nora Katabi, Vladimir Makarov, Logan A. Walsh, Ken-Wing Lee, Qingguo Wang, Joshua Armenia, Lyndsay West, Snjezana Doğan, Lu Wang, Deepa Ramaswami, Alan L. Ho, Ian Ganly, David B. Solit, Michael F. Berger, Nikolaus Schultz, Jorge S. Reis‐Filho, Timothy A. Chan, Luc G.T. Morris	2016	135
14	Radiographic Features, Patterns of Treatment Failure, and Clinical Outcomes in 56 Cases of Molecularly Subtyped Glioblastoma Multiforme Patients International Journal of Radiation OncologyBiologyPhysics ·Quincey LaPlant, Kenneth L. Pitter, Robert J. Young, Yoshiya Yamada, Timothy A. Chan, Jason T. Huse, Cameron Brennan, Kathryn Beal	2014	1
15	Frequent Somatic TERT Promoter Mutations in Thyroid Cancer: Higher Prevalence in Advanced Forms of the Disease The Journal of Clinical Endocrinology & Metabolism ·Iñigo Landa, Ian Ganly, Timothy A. Chan, Norisato Mitsutake, Michiko Matsuse, Tihana Ibrahimpašić, Ronald Ghossein, James A. Fagin	2013	337
16	IDH Mutation and Neuroglial Developmental Features Define Clinically Distinct Subclasses of Lower Grade Diffuse Astrocytic Glioma Clinical Cancer Research ·Daniel Gorovets, Kasthuri Kannan, Ronglai Shen, Edward R. Kastenhuber, Ligia Fonseca Spinel, Carl Campos, Elena Pentsova, Adriana Heguy, Suresh C. Jhanwar, Ingo K. Mellinghoff, Timothy A. Chan, Jason T. Huse	2012	114
17	Phase II Trial of Temozolomide in Patients with Relapsed Sensitive or Refractory Small Cell Lung Cancer, with Assessment of Methylguanine-DNA Methyltransferase as a Potential Biomarker Clinical Cancer Research ·M. Catherine Pietanza, Kyuichi Kadota, Kety Huberman, Camelia S. Sima, John J. Fiore, Gwen Koen Appeltants, William D. Travis, Adriana Heguy, Michelle S. Ginsberg, Andrei I. Holodny, Timothy A. Chan, Naiyer A. Rizvi, Christopher G. Azzoli, Gregory J. Riely, Mark G. Kris, Lee M. Krug	2012	122
18	Genome Sequencing Identifies a Basis for Everolimus Sensitivity Science ·Gopa Iyer, Aphrothiti J. Hanrahan, Matthew I. Milowsky, Hikmat Al‐Ahmadie, Sasinya N. Scott, Manickam Janakiraman, Mono Pirun, Chris Sander, Nicholas D. Socci, Irina Ostrovnaya, Agnès Viale, Adriana Heguy, Naveen, Timothy A. Chan, Bernard H. Bochner, Dean F. Bajorin, Michael F. Berger, Barry S. Taylor, David B. Solit Hit paper breakdown →	2012	480
19	Genomic Deregulation during Metastasis of Renal Cell Carcinoma Implements a Myofibroblast-Like Program of Gene Expression Cancer Research ·Miguel A. López-Lago, Venkata J. Thodima, Asha Guttapalli, Timothy A. Chan, Adriana Heguy, Ana M. Molina, Victor E. Reuter, Robert J. Motzer, R. S. K. Chaganti	2010	27
20	Targeted inactivation of CTNNB1 reveals unexpected effects of β-catenin mutation Proceedings of the National Academy of Sciences ·Timothy A. Chan, Zhenghe Wang, Long H. Dang, Bert Vogelstein, Kenneth W. Kinzler	2002	108

About Timothy A. Chan

Timothy A. Chan is a scholar working on Oncology, Genetics, Cancer Research, Pulmonary and Respiratory Medicine and Immunology, having authored 243 papers that have together received 22.7k indexed citations. Recurring topics across this work include Cancer Immunotherapy and Biomarkers (69 papers), Glioma Diagnosis and Treatment (44 papers), Brain Metastases and Treatment (37 papers), Cancer Genomics and Diagnostics (35 papers), Immunotherapy and Immune Responses (33 papers), Lung Cancer Research Studies (22 papers), Renal cell carcinoma treatment (19 papers) and Lung Cancer Treatments and Mutations (18 papers). The work is most often cited by research in Oncology (10.4k citations), Cancer Research (5.2k citations), Genetics (2.7k citations), Immunology (4.5k citations) and Pulmonary and Respiratory Medicine (5.5k citations). Timothy A. Chan has collaborated with scholars based in United States, Germany and Canada. Frequent co-authors include Jonathan J. Havel, Diego Chowell, Kenneth W. Kinzler, Bert Vogelstein, Luc G.T. Morris, Nadeem Riaz, Sergio A. Quezada, Albrecht Stenzinger, Charles Swanton and Solange Peters. Their work appears in journals such as International Journal of Radiation Oncology*Biology*Physics, Journal of Clinical Oncology, Clinical Cancer Research, Oncotarget and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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