Albert de la Chapelle

86.4k total citations · 16 hit papers
546 papers, 43.1k citations indexed

About

Albert de la Chapelle is a scholar working on Molecular Biology, Genetics and Pathology and Forensic Medicine. According to data from OpenAlex, Albert de la Chapelle has authored 546 papers receiving a total of 43.1k indexed citations (citations by other indexed papers that have themselves been cited), including 264 papers in Molecular Biology, 181 papers in Genetics and 116 papers in Pathology and Forensic Medicine. Recurrent topics in Albert de la Chapelle's work include Genetic factors in colorectal cancer (106 papers), Acute Myeloid Leukemia Research (66 papers) and Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (61 papers). Albert de la Chapelle is often cited by papers focused on Genetic factors in colorectal cancer (106 papers), Acute Myeloid Leukemia Research (66 papers) and Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (61 papers). Albert de la Chapelle collaborates with scholars based in Finland, United States and Hungary. Albert de la Chapelle's co-authors include Henry T. Lynch, Païvi Peltomäki, Heather Hampel, Lauri A. Aaltonen, Jukka‐Pekka Mecklin, Sandya Liyanarachchi, Reijo Salovaara, Krystian Jażdżewski, Juha Kere and Heikki Järvinen and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Albert de la Chapelle

535 papers receiving 41.6k citations

Hit Papers

Mutation of a mutL Homolog in Hereditary Colon Cancer 1987 2026 2000 2013 1994 2003 1994 2005 2005 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mutation of a mutL Homolog in Hereditary Colon Cancer
    1994 1.4k citations Henry T. Lynch, Païvi Peltomäki et al. Science profile →
  2. Hereditary Colorectal Cancer
    2003 1.4k citations Henry T. Lynch, Albert de la Chapelle New England Journal of Medicine profile →
  3. Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer
    1994 1.2k citations Albert de la Chapelle et al. profile →
  4. The role of microRNA genes in papillary thyroid carcinoma
    2005 980 citations Huiling He, Krystian Jażdżewski et al. Proceedings of the National Academy of Sciences profile →
  5. Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
    2005 973 citations Heather Hampel, Dan Fix et al. New England Journal of Medicine profile →
  6. Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA–binding protein gene
    1995 968 citations Albert de la Chapelle et al. profile →
  7. Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer
    2000 926 citations Lauri A. Aaltonen, Païvi Peltomäki et al. profile →
  8. Cancer risk in mutation carriers of DNA-mismatch-repair genes
    1999 889 citations Lauri A. Aaltonen, Albert de la Chapelle et al. profile →
  9. Hypermutability and mismatch repair deficiency in RER+ tumor cells
    1993 871 citations Albert de la Chapelle et al. profile →
  10. Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
    1998 856 citations Lauri A. Aaltonen, Paula Kristo et al. New England Journal of Medicine profile →
  11. Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma
    2008 720 citations Krystian Jażdżewski, Elizabeth Murray et al. Proceedings of the National Academy of Sciences profile →
  12. The sex-determining region of the human Y chromosome encodes a finger protein
    1987 709 citations Albert de la Chapelle et al. profile →
  13. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
    1995 678 citations Païvi Peltomäki, Albert de la Chapelle et al. profile →
  14. Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer
    2008 612 citations Heather Hampel, Mark Clendenning et al. profile →
  15. The diastrophic dysplasia gene encodes a novel sulfate transporter: Positional cloning by fine-structure linkage disequilibrium mapping
    1994 577 citations Albert de la Chapelle et al. profile →
  16. X–linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein
    1996 557 citations Juha Kere, Albert de la Chapelle et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Albert de la Chapelle Finland 103 18.9k 16.2k 12.3k 11.6k 10.5k 546 43.1k
Jean‐Pierre J. Issa United States 109 32.6k 1.7× 6.8k 0.4× 9.4k 0.8× 5.3k 0.5× 7.1k 0.7× 400 44.1k
Carl‐Henrik Heldin Sweden 132 41.7k 2.2× 3.3k 0.2× 14.1k 1.1× 4.7k 0.4× 8.9k 0.9× 494 62.7k
Rik Derynck United States 118 38.9k 2.1× 3.7k 0.2× 17.3k 1.4× 5.2k 0.4× 8.8k 0.8× 211 57.0k
Kohei Miyazono Japan 123 41.5k 2.2× 3.5k 0.2× 12.8k 1.0× 4.3k 0.4× 8.3k 0.8× 463 57.4k
Peter A. Jones United States 112 48.9k 2.6× 3.1k 0.2× 8.3k 0.7× 8.9k 0.8× 10.9k 1.0× 352 61.5k
Ramon Parsons United States 66 23.4k 1.2× 7.5k 0.5× 12.9k 1.1× 2.7k 0.2× 6.9k 0.7× 157 33.2k
Charis Eng United States 106 24.0k 1.3× 5.7k 0.4× 9.8k 0.8× 7.6k 0.7× 8.3k 0.8× 647 44.8k
Toshio Suda Japan 120 32.9k 1.7× 4.1k 0.3× 17.0k 1.4× 4.1k 0.4× 7.3k 0.7× 730 59.1k
Peter ten Dijke Netherlands 130 40.4k 2.1× 3.9k 0.2× 12.5k 1.0× 4.5k 0.4× 6.9k 0.7× 487 57.0k
Ronald A. DePinho United States 149 56.0k 3.0× 4.4k 0.3× 23.0k 1.9× 6.8k 0.6× 13.7k 1.3× 417 86.1k

Countries citing papers authored by Albert de la Chapelle

Since Specialization
Citations

This map shows the geographic impact of Albert de la Chapelle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Albert de la Chapelle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Albert de la Chapelle more than expected).

Fields of papers citing papers by Albert de la Chapelle

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Albert de la Chapelle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Albert de la Chapelle. The network helps show where Albert de la Chapelle may publish in the future.

Co-authorship network of co-authors of Albert de la Chapelle

This figure shows the co-authorship network connecting the top 25 collaborators of Albert de la Chapelle. A scholar is included among the top collaborators of Albert de la Chapelle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Albert de la Chapelle. Albert de la Chapelle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Comiskey, Daniel F., Huiling He, Sandya Liyanarachchi, et al.. (2020). Variants in LRRC34 reveal distinct mechanisms for predisposition to papillary thyroid carcinoma. Journal of Medical Genetics. 57(8). 519–527. 3 indexed citations
2.
Wang, Yanqiang, Sandya Liyanarachchi, Katherine E. Miller, et al.. (2019). Identification of Rare Variants Predisposing to Thyroid Cancer. Thyroid. 29(7). 946–955. 35 indexed citations
3.
Walker, Christopher J., Jessica Kohlschmidt, Krzysztof Mrózek, et al.. (2017). No evidence for microsatellite instability in acute myeloid leukemia. Leukemia. 31(6). 1474–1476. 9 indexed citations
4.
Eisfeld, Ann‐Kathrin, Jessica Kohlschmidt, Krzysztof Mrózek, et al.. (2016). Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality. Cancer Research. 77(1). 207–218. 16 indexed citations
5.
Walker, Christopher J., Sandya Liyanarachchi, Xiaomeng Huang, et al.. (2016). Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia. Cancer Discovery. 6(9). 1036–1051. 13 indexed citations
6.
Jendrzejewski, Jarosław, Huiling He, Hanna S. Radomska, et al.. (2012). The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type. Proceedings of the National Academy of Sciences. 109(22). 8646–8651. 207 indexed citations
7.
Hampel, Heather & Albert de la Chapelle. (2011). The Search for Unaffected Individuals with Lynch Syndrome: Do the Ends Justify the Means?. Cancer Prevention Research. 4(1). 1–5. 121 indexed citations
8.
Jażdżewski, Krystian, Sandya Liyanarachchi, Michał Świerniak, et al.. (2009). Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer. Proceedings of the National Academy of Sciences. 106(5). 1502–1505. 260 indexed citations
9.
Zeng, Qinghua, Yanfei Xu, Maureen Sadim, et al.. (2009). Tgfbr1 Haploinsufficiency Is a Potent Modifier of Colorectal Cancer Development. Cancer Research. 69(2). 678–686. 45 indexed citations
10.
He, Huiling, Rebecca Nagy, Sandya Liyanarachchi, et al.. (2009). A Susceptibility Locus for Papillary Thyroid Carcinoma on Chromosome 8q24. Cancer Research. 69(2). 625–631. 115 indexed citations
11.
Jażdżewski, Krystian, Elizabeth Murray, Kaarle Franssila, et al.. (2008). Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proceedings of the National Academy of Sciences. 105(20). 7269–7274. 720 indexed citations breakdown →
12.
Clendenning, Mark, Shuying Sun, Kyle M. Walsh, et al.. (2008). Origins and Prevalence of the American Founder Mutation of MSH2. Cancer Research. 68(7). 2145–2153. 29 indexed citations
13.
Valle, Laura, Sandya Liyanarachchi, Heather Hampel, et al.. (2008). Germline Allele-Specific Expression of TGFBR1 Confers an Increased Risk of Colorectal Cancer. Science. 321(5894). 1361–1365. 107 indexed citations
14.
Vasko, Vasily, Allan V. Espinosa, Huiling He, et al.. (2007). Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion. Proceedings of the National Academy of Sciences. 104(8). 2803–2808. 270 indexed citations
15.
Tanner, Stephan M., Cihan Öner, Mualla Çetin, et al.. (2005). Hereditary juvenile cobalamin deficiency caused by mutations in the intrinsic factor gene. Proceedings of the National Academy of Sciences. 102(11). 4130–4133. 60 indexed citations
16.
Lynch, Henry T. & Albert de la Chapelle. (2003). Hereditary Colorectal Cancer. New England Journal of Medicine. 348(10). 919–932. 1439 indexed citations breakdown →
17.
Virtaneva, Kimmo, Fred A. Wright, Stephan M. Tanner, et al.. (2001). Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics. Proceedings of the National Academy of Sciences. 98(3). 1124–1129. 226 indexed citations
18.
Simpson, Joe Leigh, Arne Ljungqvist, M.A. Ferguson‐Smith, et al.. (2000). Gender vs Sex—Reply. JAMA. 284(23). 2998–2998. 2 indexed citations
19.
Percesepe, Antonio, Paula Kristo, Lauri A. Aaltonen, et al.. (1998). Mismatch repair genes and mononucleotide tracts as mutation targets in colorectal tumors with different degrees of microsatellite instability. Oncogene. 17(2). 157–163. 60 indexed citations
20.
Chapelle, Albert de la. (1988). The Complicated Issue of Human Sex Determination. Europe PMC (PubMed Central). 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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