Michaela U. Gack

15.6k total citations · 4 hit papers
78 papers, 8.3k citations indexed

About

Michaela U. Gack is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Michaela U. Gack has authored 78 papers receiving a total of 8.3k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Immunology, 34 papers in Molecular Biology and 24 papers in Epidemiology. Recurrent topics in Michaela U. Gack's work include interferon and immune responses (54 papers), Inflammasome and immune disorders (19 papers) and Immune Response and Inflammation (19 papers). Michaela U. Gack is often cited by papers focused on interferon and immune responses (54 papers), Inflammasome and immune disorders (19 papers) and Immune Response and Inflammation (19 papers). Michaela U. Gack collaborates with scholars based in United States, Germany and Japan. Michaela U. Gack's co-authors include Jan Rehwinkel, Ying Chan, Jae U. Jung, Konstantin M. J. Sparrer, Guanqun Liu, Kyung‐Soo Inn, Meredith E. Davis-Gardner, Cindy Chiang, Michiel van Gent and Adolfo Garcı́a-Sastre and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Michaela U. Gack

78 papers receiving 8.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RIG-I-like receptors: their regulation and roles in RNA sensing

2020 1.1k citations Jan Rehwinkel, Michaela U. Gack Nature reviews. Immunology profile →
Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

2009 718 citations Michaela U. Gack, Randy A. Albrecht et al. Cell Host & Microbe profile →
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

2008 626 citations Chengyu Liang, Kyung‐Soo Inn et al. profile →
ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

2021 206 citations Guanqun Liu, Jung‐Hyun Lee et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michaela U. Gack United States	43	5.1k	3.5k	2.4k	2.0k	825	78	8.3k
Andreas Pichlmair Germany	35	4.4k 0.9×	2.9k 0.8×	1.7k 0.7×	2.2k 1.1×	575 0.7×	83	7.5k
Rune Hartmann Denmark	46	4.8k 0.9×	2.7k 0.8×	1.9k 0.8×	2.2k 1.1×	1.0k 1.2×	99	8.0k
John W. Schoggins United States	34	4.0k 0.8×	2.3k 0.7×	1.9k 0.8×	2.3k 1.2×	978 1.2×	74	8.0k
Li Wu United States	48	3.6k 0.7×	3.4k 1.0×	2.0k 0.8×	1.4k 0.7×	723 0.9×	185	9.0k
Abraham L. Brass United States	33	3.2k 0.6×	2.7k 0.8×	2.0k 0.8×	2.3k 1.2×	533 0.6×	55	7.3k
Ulrich Kalinke Germany	58	8.2k 1.6×	3.8k 1.1×	2.3k 1.0×	2.1k 1.0×	2.1k 2.5×	241	14.1k
Benjamin R. tenOever United States	50	5.3k 1.0×	4.0k 1.1×	2.5k 1.0×	4.4k 2.2×	1.2k 1.4×	103	11.5k
Jan Rehwinkel United Kingdom	41	4.6k 0.9×	6.3k 1.8×	1.2k 0.5×	1.4k 0.7×	646 0.8×	72	9.8k
Georg Kochs Germany	61	6.3k 1.2×	4.8k 1.4×	4.1k 1.7×	3.1k 1.5×	1.2k 1.5×	147	13.6k
Maryline Panis United States	17	2.3k 0.4×	1.9k 0.5×	2.1k 0.9×	2.9k 1.4×	493 0.6×	25	7.2k

Countries citing papers authored by Michaela U. Gack

Since Specialization

Citations

This map shows the geographic impact of Michaela U. Gack's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michaela U. Gack with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michaela U. Gack more than expected).

Fields of papers citing papers by Michaela U. Gack

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michaela U. Gack. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michaela U. Gack. The network helps show where Michaela U. Gack may publish in the future.

Co-authorship network of co-authors of Michaela U. Gack

This figure shows the co-authorship network connecting the top 25 collaborators of Michaela U. Gack. A scholar is included among the top collaborators of Michaela U. Gack based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michaela U. Gack. Michaela U. Gack is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Acharya, Dhiraj, Maximilian Hirschenberger, Matthew A. Zurenski, et al.. (2025). TRIM23 mediates cGAS-induced autophagy in anti-HSV defense. Nature Communications. 16(1). 4418–4418. 6 indexed citations

Zhu, Junji & Michaela U. Gack. (2025). Viral tolerance enabled by a bat-specific genomic tweak. Nature. 638(8050). 326–327. 1 indexed citations

Liu, Guanqun, et al.. (2025). MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis. Proceedings of the National Academy of Sciences. 122(14). e2420190122–e2420190122. 1 indexed citations

Wan, Quanyuan, Ting‐Yu Wang, Shu Feng, et al.. (2024). Hijacking of nucleotide biosynthesis and deamidation-mediated glycolysis by an oncogenic herpesvirus. Nature Communications. 15(1). 1442–1442. 17 indexed citations

Acharya, Dhiraj, et al.. (2024). TRIM Proteins: Key Regulators of Immunity to Herpesvirus Infection. Viruses. 16(11). 1738–1738. 1 indexed citations

Zhu, Junji, et al.. (2024). ISGylation of the SARS-CoV-2 N protein by HERC5 impedes N oligomerization and thereby viral RNA synthesis. Journal of Virology. 98(9). e0086924–e0086924. 7 indexed citations

Bazzone, Lindsey E., Junji Zhu, Michael R. King, et al.. (2024). ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection. Nature Communications. 15(1). 4153–4153. 4 indexed citations

Khan, Debjit, Fulvia Terenzi, Guanqun Liu, et al.. (2023). A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon. Nature Communications. 14(1). 3385–3385. 9 indexed citations

Hou, Yuan, Yadi Zhou, Lara Jehi, et al.. (2022). Aging‐related cell type‐specific pathophysiologic immune responses that exacerbate disease severity in aged COVID‐19 patients. Aging Cell. 21(2). e13544–e13544. 10 indexed citations

10.

Mou, Huihui, Brian D. Quinlan, Haiyong Peng, et al.. (2021). Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2. PLoS Pathogens. 17(4). e1009501–e1009501. 34 indexed citations

11.

Zhang, Jing, Jung‐Hyun Lee, Jennifer M. Mason, et al.. (2021). The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms. Cancer Research. 81(6). 1540–1551. 9 indexed citations

12.

Rehwinkel, Jan & Michaela U. Gack. (2020). RIG-I-like receptors: their regulation and roles in RNA sensing. Nature reviews. Immunology. 20(9). 537–551. 1081 indexed citations breakdown →

13.

Liu, Guanqun & Michaela U. Gack. (2020). Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity. Immunity. 53(1). 26–42. 96 indexed citations

14.

Ma, Qi, Hongyu Ruan, Lisheng Peng, et al.. (2017). Proteasome-independent polyubiquitin linkage regulates synapse scaffolding, efficacy, and plasticity. Proceedings of the National Academy of Sciences. 114(41). E8760–E8769. 41 indexed citations

15.

Chan, Ying & Michaela U. Gack. (2016). A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity. Nature Immunology. 17(5). 523–530. 96 indexed citations

16.

Chan, Ying & Michaela U. Gack. (2015). RIG-I-like receptor regulation in virus infection and immunity. Current Opinion in Virology. 12. 7–14. 144 indexed citations

17.

Rajsbaum, Ricardo, Randy A. Albrecht, May K. Wang, et al.. (2012). Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein. PLoS Pathogens. 8(11). e1003059–e1003059. 260 indexed citations

18.

Nistal‐Villán, Estanislao, Michaela U. Gack, Gustavo Martínez-Delgado, et al.. (2010). Negative Role of RIG-I Serine 8 Phosphorylation in the Regulation of Interferon-β Production. Journal of Biological Chemistry. 285(26). 20252–20261. 90 indexed citations

19.

Gack, Michaela U., Randy A. Albrecht, Tomohiko Urano, et al.. (2009). Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I. Cell Host & Microbe. 5(5). 439–449. 718 indexed citations breakdown →

20.

Gack, Michaela U., Axel Kirchhofer, Young C. Shin, et al.. (2008). Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction. Proceedings of the National Academy of Sciences. 105(43). 16743–16748. 215 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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