Chaohong Sun

7.0k citations

46 papers · 3.6k indexed · 2 hit papers · h-index 24

Impact in

Sensory Systems top 2%
- Ion Channels and Receptors
Molecular Biology top 2%
- Cell death mechanisms and regulation
- Ubiquitin and proteasome pathways
- RNA Interference and Gene Delivery
- ATP Synthase and ATPases Research

Papers in

Molecular Biology 36
- Cell death mechanisms and regulation 12
- Protein Structure and Dynamics 5
- ATP Synthase and ATPases Research 5
- Mitochondrial Function and Pathology 3
- RNA Interference and Gene Delivery 3
Geriatrics and Gerontology 2

Co-authors: Stephen W. Fesik Robert Meadows Edward T. Olejniczak Joseph C. Wu Julia Herrmann Stephen F. Betz Zhihong Liu Thorsten Oost
Journals: Bioorganic & Medicinal Chemistry Letters (9 papers)ACS Medicinal Chemistry Letters (4 papers)Journal of Biological Chemistry (4 papers)Journal of Medicinal Chemistry (3 papers)Journal of Biomolecular NMR (2 papers)
Partner nations: United States United Kingdom Spain

In The Last Decade

Chaohong Sun

44 papers receiving 3.5k citations

Hit Papers

align trajectories log scale

Structural Basis for the Inhibition of Caspase-3 by XIAP 2001 · 592 citations

Peers

Countries citing papers authored by Chaohong Sun

Since Specialization

Citations

This map shows the geographic impact of Chaohong Sun's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chaohong Sun with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chaohong Sun more than expected).

Fields of papers citing papers by Chaohong Sun

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chaohong Sun. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chaohong Sun. The network helps show where Chaohong Sun may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Chaohong Sun, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Chaohong Sun Line = papers co-authored together Chaohong Sun links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Kinase-deficient BTK mutants confer ibrutinib resistance through activation of the kinase HCK Science Signaling ·Morten Pais Ruge, Anirban Chakraborty, Tarikere Gururaja, Ashley Tipton, Chaohong Sun, Е. Б. Кудряш, Jacek Zwiernik	2022	26
2	Insights into the Conformation and Self-Association of a Concentrated Monoclonal Antibody using Isothermal Chemical Denaturation and Nuclear Magnetic Resonance Journal of Pharmaceutical Sciences ·Jianwen Xu, Andrew T. Namanja, Siew Leong Chan, Gayá González L, Andrew M. Petros, Chaohong Sun, Czeslaw Radziejewski, 남택호	2021	2
3	NMR-based fragment screening and lead discovery accelerated by principal component analysis Journal of Biomolecular NMR ·Andrew T. Namanja, Jia Xu, Haihong Wu, Qi Sun, Anup K. Upadhyay, Chaohong Sun, Steven R. Van Doren, Andrew M. Petros	2019	15
4	Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315 Journal of Medicinal Chemistry ·Clarissa G. Jakob, Anup K. Upadhyay, Wafa Al Malki, Anupam Khalkho, Sadiya N. Addo, Wei Qiu, Chris Ling, Sujatha M. Gopalakrishnan, Maricel Torrent, Steven Cepa, Auli Nevantaus, Alexander R. Shoemaker, Chaohong Sun, Anil Vasudevan, Kevin R. Woller, J. Brad Shotwell, Bailin Shaw, Zhiguo Bian, Jessica E. Hutti	2018	34
5	Quantitative ligand and receptor binding studies reveal the mechanism of interleukin-36 (IL-36) pathway activation Journal of Biological Chemistry ·Li Zhou, Viktor Todorović, J W Opishinski, Bernhard Sielaff, Swetha Pitta, Leyu Wang, Ramkrishna Sadhukhan, Henning Stöckmann, Paul L. Richardson, Enrico L. DiGiammarino, Chaohong Sun, Victoria Scott	2017	28
6	Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein Bioorganic & Medicinal Chemistry Letters ·Andrew M. Petros, T. J. Dupuy, Danying Song, Kerren K. Swinger, Chang Park, Haichao Zhang, Michael Wendt, Aaron Kunzer, Andrew J. Souers, Chaohong Sun	2014	63
7	Species differences and molecular determinant of TRPA1 cold sensitivity Nature Communications ·Jun Chen, Dawon Kang, Jing Xu, Marc Lake, 林怜史, Chaohong Sun, Karl A. Walter, Betty Yao, Donghee Kim	2013	195
8	Cracking the molecular weight barrier: Fragment screening of an aminotransferase using an NMR-based functional assay Bioorganic & Medicinal Chemistry Letters ·Renaldo Mendoza, Andrew M. Petros, Yaya Liu, Rama Thimmapaya, Carol S. Surowy, Hank C. Wu, Lior Jankelson, Sanjay C. Panchal, Chaohong Sun	2011	0
9	Fragment-based lead discovery: challenges and opportunities Journal of Computer-Aided Molecular Design ·Chaohong Sun, Andrew M. Petros, Philip J. Hajduk	2011	20
10	Labeled Ligand Displacement: Extending NMR-Based Screening of Protein Targets ACS Medicinal Chemistry Letters ·T. J. Dupuy, Danying Song, Chaohong Sun, Philip J. Hajduk, Andrew M. Petros	2010	10
11	Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR Bioorganic & Medicinal Chemistry Letters ·Andrew M. Petros, Jeffrey R. Huth, Thorsten Oost, Cheol‐Min Park, Hong Ding, Xilu Wang, Haichao Zhang, Paul Nimmer, Renaldo Mendoza, Chaohong Sun, J. Mack, Karl A. Walter, Sarah A. Dorwin, Professor, INM, INHS Asvini, Mumbai, Uri S. Ladror, Saul H. Rosenberg, Steven W. Elmore, Stephen W. Fesik, Philip J. Hajduk	2010	51
12	Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode Bioorganic & Medicinal Chemistry Letters ·Thomas W von Geldern, Chunqiu Lai, Rebecca J. Gum, Yanggui Xu, Chaohong Sun, Elizabeth H. Fry, Celerino Abad‐Zapatero	2006	48
13	High-level bacterial expression and purification of human SirT2 protein for NMR studies Protein Expression and Purification ·Chaohong Sun, Danying Song, Patrick A. Marcotte, Paul L. Richardson, Philip J. Hajduk	2006	2
14	NMR in Pharmacokinetic and Pharmacodynamic Profiling ChemBioChem ·Chaohong Sun, Jeffrey R. Huth, Philip J. Hajduk	2005	13
15	Utilization of NMR-Derived Fragment Leads in Drug Design Methods in enzymology on CD-ROM/Methods in enzymology ·Jeffrey R. Huth, Chaohong Sun, Daryl R. Sauer, Philip J. Hajduk	2005	25
16	Regulation of the Apaf-1/Caspase-9 Apoptosome by Caspase-3 and XIAP Journal of Biological Chemistry ·Hua Zou, Ruomei Yang, Junshan Hao, Jean Wang, Chaohong Sun, Stephen W. Fesik, Joseph C. Wu, Kevin J. Tomaselli, Robert C. Armstrong	2003	174
17	Utility of NMR in Lead Optimization: Fragment-Based Approaches Combinatorial Chemistry & High Throughput Screening ·Jeffrey R. Huth, Chaohong Sun	2002	19
18	Structural Basis for the Inhibition of Caspase-3 by XIAP Cell ·Stefan J. Riedl, Martin Renatus, Robert Schwarzenbacher, Qiao Zhou, Chaohong Sun, Stephen W. Fesik, Robert Liddington, Guy S. Salvesen Hit paper breakdown →	2001	592
19	The Ig fold of the core binding factor α Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains Structure ·Marcelo J. Berardi, Chaohong Sun, نیلوفر وکیل, Frits Abildgaard, Jeff Peng, Nancy A. Speck, John H. Bushweller	1999	70
20	NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP Nature ·Chaohong Sun, Mengli Cai, Angelo Gunasekera, Robert Meadows, Hong Wang, Jun Chen, Haichao Zhang, Wei Wu, Nan Xu, Shi‐Chung Ng, Stephen W. Fesik	1999	272

About Chaohong Sun

Chaohong Sun is a scholar working on Molecular Biology, Geriatrics and Gerontology, Sensory Systems, Computational Theory and Mathematics and Pharmacology, having authored 46 papers that have together received 3.6k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (12 papers), Enzyme Structure and Function (8 papers), Computational Drug Discovery Methods (6 papers), Protein Structure and Dynamics (5 papers), ATP Synthase and ATPases Research (5 papers), Mitochondrial Function and Pathology (3 papers), RNA Interference and Gene Delivery (3 papers) and Mass Spectrometry Techniques and Applications (3 papers). The work is most often cited by research in Sensory Systems (241 citations), Molecular Biology (2.8k citations), Oncology (524 citations), Immunology (399 citations) and Toxicology (62 citations). Chaohong Sun has collaborated with scholars based in United States, United Kingdom and Spain. Frequent co-authors include Stephen W. Fesik, Robert Meadows, Edward T. Olejniczak, Joseph C. Wu, Julia Herrmann, Stephen F. Betz, Zhihong Liu, Thorsten Oost, Robert Schwarzenbacher and Qiao Zhou. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, ACS Medicinal Chemistry Letters, Journal of Biological Chemistry, Journal of Medicinal Chemistry and Journal of Biomolecular NMR.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact