Thorsten Oost

1.9k total citations · 1 hit paper
21 papers, 1.2k citations indexed

About

Thorsten Oost is a scholar working on Molecular Biology, Neurology and Organic Chemistry. According to data from OpenAlex, Thorsten Oost has authored 21 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 4 papers in Neurology and 3 papers in Organic Chemistry. Recurrent topics in Thorsten Oost's work include Receptor Mechanisms and Signaling (5 papers), Botulinum Toxin and Related Neurological Disorders (4 papers) and RNA Interference and Gene Delivery (3 papers). Thorsten Oost is often cited by papers focused on Receptor Mechanisms and Signaling (5 papers), Botulinum Toxin and Related Neurological Disorders (4 papers) and RNA Interference and Gene Delivery (3 papers). Thorsten Oost collaborates with scholars based in Germany, United States and Austria. Thorsten Oost's co-authors include Stephen W. Fesik, Chaohong Sun, Robert Meadows, Edward T. Olejniczak, Stephen F. Betz, Joseph C. Wu, Julia Herrmann, Zhihong Liu, Saul H. Rosenberg and Hong Ding and has published in prestigious journals such as Nature, Journal of the American Chemical Society and Journal of Medicinal Chemistry.

In The Last Decade

Thorsten Oost

20 papers receiving 1.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

2000 511 citations Zhihong Liu, Chaohong Sun et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thorsten Oost Germany	12	998	210	188	154	108	21	1.2k
Bainan Wu United States	22	880 0.9×	244 1.2×	150 0.8×	103 0.7×	56 0.5×	28	1.2k
Paul T. Wilder United States	24	1.3k 1.3×	135 0.6×	196 1.0×	213 1.4×	48 0.4×	50	1.5k
Jonathan H. Shrimp United States	14	613 0.6×	304 1.4×	85 0.5×	129 0.8×	65 0.6×	25	982
Guixian Jin United States	15	714 0.7×	264 1.3×	108 0.6×	86 0.6×	65 0.6×	21	1.1k
Ciro Mercurio Italy	24	1.4k 1.4×	469 2.2×	298 1.6×	90 0.6×	98 0.9×	52	1.9k
Brinton Seashore‐Ludlow Sweden	20	649 0.7×	186 0.9×	298 1.6×	64 0.4×	53 0.5×	51	1.1k
Matthew F. Calabrese United States	14	1.6k 1.6×	470 2.2×	72 0.4×	68 0.4×	148 1.4×	20	1.9k
Dennis Goldfarb United States	17	1.1k 1.1×	212 1.0×	77 0.4×	116 0.8×	72 0.7×	42	1.4k
S.E. Greasley United States	19	726 0.7×	153 0.7×	165 0.9×	115 0.7×	44 0.4×	25	935
Landon R. Whitby United States	19	914 0.9×	191 0.9×	452 2.4×	201 1.3×	85 0.8×	24	1.4k

Countries citing papers authored by Thorsten Oost

Since Specialization

Citations

This map shows the geographic impact of Thorsten Oost's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thorsten Oost with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thorsten Oost more than expected).

Fields of papers citing papers by Thorsten Oost

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thorsten Oost. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thorsten Oost. The network helps show where Thorsten Oost may publish in the future.

Co-authorship network of co-authors of Thorsten Oost

This figure shows the co-authorship network connecting the top 25 collaborators of Thorsten Oost. A scholar is included among the top collaborators of Thorsten Oost based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thorsten Oost. Thorsten Oost is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kuttruff, Christian A., Martin Fleck, Sebastian Carotta, et al.. (2023). Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer. Journal of Medicinal Chemistry. 66(14). 9376–9400. 12 indexed citations

Gnamm, Christian, et al.. (2020). In vitro and in vivo characterisation of the novel neutrophil elastase inhibitor BI 1323495. 3303–3303. 1 indexed citations

Geneste, Hervé, Marcel M. van Gaalen, Wilfried Hornberger, et al.. (2018). Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 28(19). 3260–3264. 4 indexed citations

Roth, Gerald J., Armin Heckel, Thorsten Lehmann, et al.. (2015). Design, synthesis and evaluation of MCH receptor 1 antagonists—Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibition. Bioorganic & Medicinal Chemistry Letters. 25(16). 3270–3274. 8 indexed citations

Oost, Thorsten, Armin Heckel, Thorsten Lehmann, et al.. (2015). Design, synthesis and evaluation of MCH receptor 1 antagonists—Part III: Discovery of pre-clinical development candidate BI 186908. Bioorganic & Medicinal Chemistry Letters. 25(16). 3275–3280. 6 indexed citations

Müller, Stephan, Armin Heckel, Thorsten Lehmann, et al.. (2015). Design, synthesis and evaluation of MCH receptor 1 antagonists—Part I: Optimization of HTS hits towards an in vivo efficacious tool compound BI 414. Bioorganic & Medicinal Chemistry Letters. 25(16). 3264–3269. 2 indexed citations

Oost, Thorsten, Gisela Backfisch, Marcel M. van Gaalen, et al.. (2011). Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties. Bioorganic & Medicinal Chemistry Letters. 21(12). 3828–3831. 43 indexed citations

Petros, Andrew M., Jeffrey R. Huth, Thorsten Oost, et al.. (2010). Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR. Bioorganic & Medicinal Chemistry Letters. 20(22). 6587–6591. 51 indexed citations

Oost, Thorsten, et al.. (2004). Synthesis of substrates and inhibitors of botulinum neurotoxin type A metalloprotease*. Journal of Peptide Research. 63(2). 181–193. 30 indexed citations

10.

Oost, Thorsten, Chaohong Sun, Robert C. Armstrong, et al.. (2004). Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer. Journal of Medicinal Chemistry. 47(18). 4417–4426. 305 indexed citations

11.

Yu, Liping, et al.. (2003). Discovery of Aminoglycoside Mimetics by NMR-Based Screening of Escherichia c oli A-site RNA. Journal of the American Chemical Society. 125(15). 4444–4450. 70 indexed citations

12.

Oost, Thorsten, Matthias Brewer, Michael C. Goodnough, et al.. (2003). Design and synthesis of substrate‐based inhibitors of botulinum neurotoxin type B metalloprotease. Biopolymers. 71(6). 602–619. 16 indexed citations

13.

Xin, Zhili, Thorsten Oost, Cele Abad‐Zapatero, et al.. (2003). Potent, selective inhibitors of protein tyrosine phosphatase 1B. Bioorganic & Medicinal Chemistry Letters. 13(11). 1887–1890. 40 indexed citations

14.

Hanson, Michael A., et al.. (2002). Structural Basis for BABIM Inhibition of Botulinum Neurotoxin Type B Protease [J. Am. Chem. Soc. 2000, 122, 11268−11269].. Journal of the American Chemical Society. 124(34). 10248–10248. 7 indexed citations

15.

Brewer, Matthias, et al.. (2002). Sequencing Hydroxyethylamine-Containing Peptides via Edman Degradation. Organic Letters. 4(20). 3469–3472. 5 indexed citations

16.

Liu, Zhihong, Chaohong Sun, Edward T. Olejniczak, et al.. (2000). Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature. 408(6815). 1004–1008. 511 indexed citations breakdown →

17.

Kalesse, Markus & Thorsten Oost. (1999). Synthesis of RNAse Active Site Model Systems Using a Steroid Template. Polish Journal of Chemistry. 73(1). 89–99.

18.

Oost, Thorsten, et al.. (1997). Bis(guanidinium) Receptors as Ribonuclease Active‐Site Model Systems: Structural Changes and Solvent Effects. Liebigs Annalen. 1997(5). 1005–1011. 12 indexed citations

19.

Oost, Thorsten & Markus Kalesse. (1997). Synthesis of RNAse active site model systems using a steroid template. Tetrahedron. 53(25). 8421–8438. 23 indexed citations

20.

Maier, Martin E. & Thorsten Oost. (1995). Regio- and diastereo-selectivity of the insertion of aldehydes into alkyne zirconocene complexes. Journal of Organometallic Chemistry. 505(1). 95–107. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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