Shi‐Chung Ng

5.0k citations

41 papers · 4.0k indexed · 1 hit paper · h-index 29

Impact in

Molecular Biology top 2%
- Cell death mechanisms and regulation
- RNA Interference and Gene Delivery
- Mitochondrial Function and Pathology
- Ubiquitin and proteasome pathways
- DNA Repair Mechanisms
Cell Biology top 2%
- Microtubule and mitosis dynamics

Papers in

Aging 1
Molecular Biology 36
- Cell death mechanisms and regulation 13
- RNA Interference and Gene Delivery 6
- DNA Repair Mechanisms 5
- Cancer therapeutics and mechanisms 5
- Retinoids in leukemia and cellular processes 4

Co-authors: Stephen W. Fesik Mark C. Fishman Sui‐Lam Wong Robert Meadows Saul H. Rosenberg Steven W. Muchmore Larry R. Karns Haichao Zhang
Journals: Neoplasia (3 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Analytical Biochemistry (3 papers)Nature (2 papers)Journal of Medicinal Chemistry (2 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

Shi‐Chung Ng

41 papers receiving 3.9k citations

Hit Papers

align trajectories log scale

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death 1996 · 1.2k citations

Peers

Countries citing papers authored by Shi‐Chung Ng

Since Specialization

Citations

This map shows the geographic impact of Shi‐Chung Ng's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shi‐Chung Ng with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shi‐Chung Ng more than expected).

Fields of papers citing papers by Shi‐Chung Ng

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shi‐Chung Ng. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shi‐Chung Ng. The network helps show where Shi‐Chung Ng may publish in the future.

Co-authors

The 25 scholars most cited alongside Shi‐Chung Ng, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Shi‐Chung Ng Line = papers co-authored together Shi‐Chung Ng links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Crystal structure of HsEg5 in complex with clinical candidate CK0238273 provides insight into inhibitory mechanism, potency, and specificity Biochemical and Biophysical Research Communications ·Bin Zhang, Jifeng Liu, Yingwu Xu, Shi‐Chung Ng	2008	20
2	Bexarotene (LGD1069, Targretin), a Selective Retinoid X Receptor Agonist, Prevents and Reverses Gemcitabine Resistance in NSCLC Cells by Modulating Gene Amplification Cancer Research ·Patricia Tooker, Wan-Ching Yen, Shi‐Chung Ng, A. Negro‐Vilar, Thomas Hermann	2007	54
3	Influence of Bcl-2 Family Members on the Cellular Response of Small-Cell Lung Cancer Cell Lines to ABT-737 Cancer Research ·Stephen K. Tahir, Xiufen Yang, Mark G. Anderson, Susan E. Morgan-Lappe, Aparna V. Sarthy, Jun Chen, Robert B. Warner, Shi‐Chung Ng, Stephen W. Fesik, Steve W. Elmore, Saul H. Rosenberg, Christin Tse	2007	250
4	Identification of a Small Molecule That Induces Mitotic Arrest Using a Simplified High-Content Screening Assay and Data Analysis Method SLAS DISCOVERY ·Christopher J. Wilson, Ying Si, Craig M. Thompson, Andrew Smellie, Mark A. Ashwell, Jifeng Liu, Ping Ye, Daniel Yohannes, Shi‐Chung Ng	2006	29
5	Indoloprodigiosins from the C-10 bipyrrolic precursor: New antiproliferative prodigiosin analogs Bioorganic & Medicinal Chemistry Letters ·Carmen M. Baldino, J. Parr, Christopher J. Wilson, Shi‐Chung Ng, Daniel Yohannes, Harry H. Wasserman	2005	29
6	Development of a high-throughput robotic fluorescence-based assay for HsEg5 inhibitor screening Analytical Biochemistry ·Bin Zhang, David Senator, Christopher J. Wilson, Shi‐Chung Ng	2005	10
7	Privileged structure-based quinazolinone natural product-templated libraries: Identification of novel tubulin polymerization inhibitors Bioorganic & Medicinal Chemistry Letters ·Jifeng Liu, Christopher J. Wilson, Ye Ping, Kevin Sprague, Katie Sargent, Ying Si, Galina Beletsky, Daniel Yohannes, Shi‐Chung Ng	2005	45
8	Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms Analytical Biochemistry ·Jie Qian, Martin J. Voorbach, Jeffrey R. Huth, Michael Coen, Haichao Zhang, Shi‐Chung Ng, Kenneth M. Comess, Andrew M. Petros, Saul H. Rosenberg, Usha Warrior, David J. Burns	2004	56
9	Divergence of Genbank and human tumor Bcl-2 sequences and implications for binding affinity to key apoptotic proteins Oncogene ·Mary K. Joseph, Larry R. Solomon, Andrew M. Petros, Jinghao Cai, Robert L. Simmer, Haichao Zhang, Saul H. Rosenberg, Shi‐Chung Ng	2004	4
10	Development of a high-throughput fluorescence polarization assay for Bcl-xL Analytical Biochemistry ·Haichao Zhang, Paul Nimmer, Saul H. Rosenberg, Shi‐Chung Ng, Mary K. Joseph	2002	68
11	Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents. PubMed ·Yan Luo, Shayna K. Rockow-Magnone, Mary K. Joseph, Jay Bradner, Christopher Butler, Stephen K. Tahir, Edward K. Han, Shi‐Chung Ng, Jean M. Severin, Earl J. Gubbins, Regina M. Reilly, Annemarie Rueter, Robert L. Simmer, Tom Holzman, Vincent L. Giranda	2001	28
12	Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells Neoplasia ·Xuesong Liu, Yan Shi, Edward K. Han, Zehan Chen, Saul H. Rosenberg, Vincent L. Giranda, Yan Luo, Shi‐Chung Ng	2001	40
13	Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth Neoplasia ·Jun Chen, Wei Wu, Stephen K. Tahir, Paul E. Kroeger, Saul H. Rosenberg, Lex M. Cowsert, Frank Bennett, Stanisław Krajewski, Maryla Krajewska, Kate Welsh, John C. Reed, Shi‐Chung Ng	2000	169
14	NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP Nature ·Chaohong Sun, Mengli Cai, Angelo Gunasekera, Robert Meadows, Hong Wang, Jun Chen, Haichao Zhang, Wei Wu, Nan Xu, Shi‐Chung Ng, Stephen W. Fesik	1999	272
15	Potent inhibitors of protein farnesyltransferase: Heteroarenes as cysteine replacements Bioorganic & Medicinal Chemistry Letters ·Shen Wang, Stephen A. Fakhoury, Greg Donner, Kenneth J. Henry, Jang Lee, Haichao Zhang, Jerry D. Cohen, Robert R. Warner, Badr Saeed, Sajeev Cherian, Stephen K. Tahir, Peter Kovar, Joy Bauch, Shi‐Chung Ng, Kennan Marsh, Hing L. Sham, Saul H. Rosenberg	1999	7
16	Apoptotic program is initiated but not completed in LNCaP cells in response to growth in charcoal-stripped media The Prostate ·Badr Saeed, Haichao Zhang, Shi‐Chung Ng	1997	25
17	Aliphatic 1H and 13C resonance assignments for the 26-10 antibody VL domain derived from heteronuclear multidimensional NMR spectroscopy Journal of Biomolecular NMR ·KeithL. Constantine, Valentina Goldfarb, Michael Wittekind, MarkS. Friedrichs, James Anthony, Shi‐Chung Ng, Luciano Mueller	1993	26
18	Efficient Production of a Functional Single-Chain Antidigoxin Antibody via an Engineered Bacillus subtilis Expression-Secretion System Nature Biotechnology ·Xuchu Wu, Shi‐Chung Ng, Richard I. Near, Sui‐Lam Wong	1993	66
19	GAP-43 gene expression during development: persistence in a distinctive set of neurons in the mature central nervous system Developmental Brain Research ·Suzanne M. de la Monte, Howard J. Federoff, Shi‐Chung Ng, Ed Grabczyk, Mark C. Fishman	1989	172
20	Cloning of human GAP 43: Growth association and ischemic resurgence Neuron ·Shi‐Chung Ng, Suzanne M. de la Monte, Gary L. Conboy, Larry R. Karns, Mark C. Fishman	1988	129

About Shi‐Chung Ng

Shi‐Chung Ng is a scholar working on Aging, Molecular Biology, Cell Biology, Oncology and Cancer Research, having authored 41 papers that have together received 4.0k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (13 papers), Microtubule and mitosis dynamics (7 papers), RNA Interference and Gene Delivery (6 papers), Cancer-related Molecular Pathways (5 papers), DNA Repair Mechanisms (5 papers), Cancer therapeutics and mechanisms (5 papers), Quinazolinone synthesis and applications (4 papers) and Retinoids in leukemia and cellular processes (4 papers). The work is most often cited by research in Molecular Biology (3.2k citations), Cell Biology (518 citations), Oncology (790 citations), Developmental Neuroscience (118 citations) and Cellular and Molecular Neuroscience (457 citations). Shi‐Chung Ng has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Stephen W. Fesik, Mark C. Fishman, Sui‐Lam Wong, Robert Meadows, Saul H. Rosenberg, Steven W. Muchmore, Larry R. Karns, Haichao Zhang, John E. Harlan and David G. Nettesheim. Their work appears in journals such as Neoplasia, Bioorganic & Medicinal Chemistry Letters, Analytical Biochemistry, Nature and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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