Joseph C. Wu

68.9k citations

671 papers · 40.1k indexed · 12 hit papers · h-index 108

Impact in

Molecular Biology top 0.05%
- Pluripotent Stem Cells Research
- CRISPR and Genetic Engineering
- Congenital heart defects research
Genetics top 0.1%
- Mesenchymal stem cell research

Papers in

Cardiology and Cardiovascular Medicine 164
- Cardiomyopathy and Myosin Studies 53
Molecular Biology 430
- Pluripotent Stem Cells Research 228
- CRISPR and Genetic Engineering 121
- Congenital heart defects research 71

Co-authors: Paul W. Burridge Robert C. Robbins Sanjiv S. Gambhir Kitchener D. Wilson Zongjin Li Elena Matsa Shijun Hu Ning Sun
Journals: Circulation (46 papers)Circulation Research (42 papers)Stem Cell Research (33 papers)Journal of the American College of Cardiology (15 papers)Cell stem cell (14 papers)
Partner nations: United States India China

In The Last Decade

Joseph C. Wu

647 papers receiving 39.5k citations

Hit Papers

12 papers align trajectories log scale

Artificial intelligence in drug development 2025 · 110 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2025 Nature Medicine
2024 Bioinformatics
2023 Journal of Clinical Investigation
2022 Nature Biomedical Engineering
2020 Nature Reviews Cardiology
2016 Nature Medicine
2016 Nature Reviews Drug Discovery
2014 Nature Methods
2013 Nature Medicine
2010 Nature Methods
2000 Nature
1990 Science

Peers

Countries citing papers authored by Joseph C. Wu

Since Specialization

Citations

This map shows the geographic impact of Joseph C. Wu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph C. Wu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph C. Wu more than expected).

Fields of papers citing papers by Joseph C. Wu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph C. Wu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph C. Wu. The network helps show where Joseph C. Wu may publish in the future.

Co-authors

The 25 scholars most cited alongside Joseph C. Wu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Joseph C. Wu Line = papers co-authored together Joseph C. Wu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	ADMET-AI: a machine learning ADMET platform for evaluation of large-scale chemical libraries Bioinformatics ·Kyle Swanson, Parker Walther, Jeremy Leitz, Souhrid Mukherjee, Joseph C. Wu, Rabindra V. Shivnaraine, James Zou Hit paper breakdown →	2024	88
2	CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity Cell stem cell ·Chunying Liu, Mengcheng Shen, Yanxia Liu, Amit Manhas, Rui Zhao, Mao Zhang, Nadjet Belbachir, Lu Ren, Joe Z. Zhang, Arianne Caudal, Masataka Nishiga, Dilip Thomas, Angela Zhang, Huaxiao Yang, Yang Zhou, Mohamed Ameen, Nazish Sayed, June‐Wha Rhee, Lei S. Qi, Joseph C. Wu	2024	13
3	Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction Nature Biomedical Engineering ·Chengyi Tu, Arianne Caudal, Yu Liu, Nikoloz Gorgodze, Hao Zhang, Chi Keung Lam, Yuqin Dai, Angela Zhang, Alexa Wnorowski, Matthew A. Wu, Huaxiao Yang, Oscar J. Abilez, Xuchao Lyu, Sanjiv M. Narayan, Luisa Mestroni, Matthew R.G. Taylor, Fabio A. Recchia, Joseph C. Wu	2023	18
4	Acoustic Fabrication of Living Cardiomyocyte-based Hybrid Biorobots ACS Nano ·Jie Wang, Fernando Soto, Peng Ma, Rajib Ahmed, Huaxiao Yang, Sihan Chen, Ji‐Bo Wang, Chun Liu, Demir Akin, Kaiyu Fu, Xu Cao, Pu Chen, En‐Chi Hsu, H. Tom Soh, Tanya Stoyanova, Joseph C. Wu, Utkan Demirci	2022	27
5	Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction European Heart Journal ·Siyeon Rhee, David T. Paik, Johnson Y. Yang, Danielle Nagelberg, Ian M. Williams, Lei Tian, R A Roth, Mark Chandy, Jiyeon Ban, Nadjet Belbachir, Seokho Kim, Hao Zhang, Ragini Phansalkar, Ka Man Wong, D. King, Caroline Valdez, Virginia D. Winn, Ashby J. Morrison, Joseph C. Wu, Kristy Red‐Horse	2021	41
6	Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome Human Molecular Genetics ·Nadja Makki, Jingjing Zhao, Zhaoyang Liu, Walter L. Eckalbar, Aki Ushiki, Anas M. Khanshour, Joseph C. Wu, Jonathan J. Rios, Ryan S. Gray, Carol A. Wise, Nadav Ahituv	2020	5
7	Exosomes From Induced Pluripotent Stem Cell–Derived Cardiomyocytes Promote Autophagy for Myocardial Repair Journal of the American Heart Association ·Michelle Santoso, Gentaro Ikeda, Yuko Tada, Ji‐Hye Jung, Evgeniya Vaskova, Raymond G. Sierra, Cornelius Gati, Andrew B. Goldstone, Daniel von Bornstaedt, Praveen Shukla, Joseph C. Wu, Soichi Wakatsuki, Y. Joseph Woo, Phillip C. Yang	2020	88
8	Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cell Reports ·June‐Wha Rhee, Hyoju Yi, Dilip Thomas, Chi Keung Lam, Nadjet Belbachir, Lei Tian, Xulei Qin, Jessica Malisa, Edward Lau, David T. Paik, Youngkyun Kim, Beatrice SeungHye Choi, Nazish Sayed, Karim Sallam, Ronglih Liao, Joseph C. Wu	2020	39
9	Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer Circulation ·Tomoya Kitani, Sang‐Ging Ong, Chi Keung Lam, June‐Wha Rhee, Joe Z. Zhang, Angelos Oikonomopoulos, Nan Ma, Lei Tian, Jaecheol Lee, Melinda L. Telli, Ronald Witteles, Arun Sharma, Nazish Sayed, Joseph C. Wu	2019	148
10	Systematic Characterization of Long Noncoding RNAs Reveals the Contrasting Coordination of Cis - and Trans -Molecular Regulation in Human Fetal and Adult Hearts Circulation Cardiovascular Genetics ·Chunjiang He, Hanyang Hu, Kitchener D. Wilson, Haodi Wu, Jing Feng, Siyu Xia, Jared M. Churko, Kun Qu, Howard Y. Chang, Joseph C. Wu	2016	38
11	Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210 Cancer Research ·Muhammad Zaeem Noman, Bassam Janji, Shijun Hu, Joseph C. Wu, Fabio Martelli, Vincenzo Bronte, Salem Chouaı̈b	2015	123
12	Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies Advanced Drug Delivery Reviews ·Evangeline Tzatzalos, Oscar J. Abilez, Praveen Shukla, Joseph C. Wu	2015	111
13	Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model Circulation Research ·Johannes Riegler, Malte Tiburcy, Antje Ebert, Evangeline Tzatzalos, Uwe Raaz, Oscar J. Abilez, Qi Shen, Nigel G. Kooreman, Evgenios Neofytou, Vincent C. Chen, Mouer Wang, Tim Meyer, Philip S. Tsao, Andrew J. Connolly, Larry A. Couture, Joseph Gold, Wolfram H. Zimmermann, Joseph C. Wu	2015	167
14	Biomaterial applications in cardiovascular tissue repair and regeneration Expert Review of Cardiovascular Therapy ·Mai T. Lam, Joseph C. Wu	2012	131
15	Dissecting the Oncogenic and Tumorigenic Potential of Differentiated Human Induced Pluripotent Stem Cells and Human Embryonic Stem Cells Cancer Research ·Zhumur Ghosh, Mei Huang, Shijun Hu, Kitchener D. Wilson, Devaveena Dey, Joseph C. Wu	2011	73
16	Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem Cells Cancer Research ·Kitchener D. Wilson, Ning Sun, Mei Huang, Wendy Y. Zhang, Andrew S. Lee, Zongjin Li, Shan X. Wang, Joseph C. Wu	2010	63
17	Human Neural Stem Cell Grafts Modify Microglial Response and Enhance Axonal Sprouting in Neonatal Hypoxic–Ischemic Brain Injury Stroke ·Marcel M. Daadi, Alexis S. Davis, Ahmet Arac, Zongjin Li, Anne-Lise Maag, Rishi Bhatnagar, Kewen Jiang, Guohua Sun, Joseph C. Wu, Gary K. Steinberg	2010	152
18	Noninvasive De novo Imaging of Human Embryonic Stem Cell–Derived Teratoma Formation Cancer Research ·Feng Cao, Zibo Li, Andrew Lee, Zhaofei Liu, Kai Chen, Hui Wang, Weibo Cai, Xiaoyuan Chen, Joseph C. Wu	2009	47
19	Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells Proceedings of the National Academy of Sciences ·Ning Sun, Nicholas J. Panetta, Deepak Gupta, Kitchener D. Wilson, Andrew Lee, Fangjun Jia, Shijun Hu, Athena M. Cherry, Robert C. Robbins, Michael T. Longaker, Joseph C. Wu	2009	376
20	A Simple Kinetic Method for Rapid Mechanistic Analysis of Reversible Enzyme Inhibitors Assay and Drug Development Technologies ·Chung-Jeng Lai, Joseph C. Wu	2003	19

About Joseph C. Wu

Joseph C. Wu is a scholar working on Cardiology and Cardiovascular Medicine, Molecular Biology, Genetics, Surgery and Cellular and Molecular Neuroscience, having authored 671 papers that have together received 40.1k indexed citations. Recurring topics across this work include Pluripotent Stem Cells Research (228 papers), CRISPR and Genetic Engineering (121 papers), Tissue Engineering and Regenerative Medicine (118 papers), 3D Printing in Biomedical Research (80 papers), Congenital heart defects research (71 papers), Neuroscience and Neural Engineering (56 papers), Mesenchymal stem cell research (55 papers) and Cardiomyopathy and Myosin Studies (53 papers). The work is most often cited by research in Molecular Biology (24.6k citations), Genetics (3.6k citations), Cardiology and Cardiovascular Medicine (6.5k citations), Biomaterials (3.3k citations) and Cellular and Molecular Neuroscience (4.2k citations). Joseph C. Wu has collaborated with scholars based in United States, India and China. Frequent co-authors include Paul W. Burridge, Robert C. Robbins, Sanjiv S. Gambhir, Kitchener D. Wilson, Zongjin Li, Elena Matsa, Shijun Hu, Ning Sun, Patricia K. Nguyen and Feng Cao. Their work appears in journals such as Circulation, Circulation Research, Stem Cell Research, Journal of the American College of Cardiology and Cell stem cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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