Francis Ka-Ming Chan

23.0k total citations · 5 hit papers
69 papers, 11.1k citations indexed

About

Francis Ka-Ming Chan is a scholar working on Molecular Biology, Immunology and Cancer Research. According to data from OpenAlex, Francis Ka-Ming Chan has authored 69 papers receiving a total of 11.1k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Molecular Biology, 46 papers in Immunology and 16 papers in Cancer Research. Recurrent topics in Francis Ka-Ming Chan's work include Cell death mechanisms and regulation (44 papers), Inflammasome and immune disorders (19 papers) and interferon and immune responses (18 papers). Francis Ka-Ming Chan is often cited by papers focused on Cell death mechanisms and regulation (44 papers), Inflammasome and immune disorders (19 papers) and interferon and immune responses (18 papers). Francis Ka-Ming Chan collaborates with scholars based in United States, Brazil and China. Francis Ka-Ming Chan's co-authors include Kenta Moriwaki, David Moquin, Michael J. Lenardo, Sreerupa Challa, Richard M. Siegel, Thomas J. McQuade, Melissa Guildford, Tathagat Dutta Ray, Ryan M. Genga and Lixin Zheng and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Francis Ka-Ming Chan

68 papers receiving 10.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

2009 1.9k citations Sreerupa Challa, David Moquin et al. Cell profile →
The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

2012 947 citations Thomas J. McQuade, Kenta Moriwaki et al. Cell profile →
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

1999 798 citations Michael J. Lenardo, Francis Ka-Ming Chan et al. profile →
Necroptosis: Mechanisms and Relevance to Disease

2016 532 citations Francis Ka-Ming Chan et al. profile →
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations

2000 504 citations Richard M. Siegel, Francis Ka-Ming Chan et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Francis Ka-Ming Chan United States	42	7.5k	5.3k	1.5k	1.5k	1.4k	69	11.1k
Michelle A. Kelliher United States	52	6.8k 0.9×	5.1k 1.0×	1.1k 0.7×	1.6k 1.1×	2.3k 1.6×	95	10.9k
Marta Muzio Italy	41	5.7k 0.8×	6.9k 1.3×	1.5k 1.0×	1.6k 1.1×	2.0k 1.4×	88	12.2k
Christopher P. Dillon United States	34	7.1k 0.9×	4.3k 0.8×	1.8k 1.2×	1.2k 0.8×	1.3k 1.0×	46	10.6k
Peter J. Gough United States	45	6.0k 0.8×	4.4k 0.8×	1.2k 0.8×	1.5k 1.0×	1.4k 1.0×	80	9.6k
Lixin Zheng United States	49	5.2k 0.7×	5.6k 1.0×	2.2k 1.4×	1.6k 1.1×	1.3k 0.9×	98	11.9k
Andrew Oberst United States	42	6.4k 0.9×	3.6k 0.7×	1.4k 0.9×	1.2k 0.8×	957 0.7×	64	8.3k
Mathieu J.M. Bertrand Belgium	43	5.6k 0.7×	3.6k 0.7×	1.3k 0.8×	1.2k 0.8×	1.5k 1.1×	78	8.2k
Domagoj Vucic United States	50	9.7k 1.3×	4.1k 0.8×	1.5k 0.9×	2.4k 1.6×	2.2k 1.5×	93	12.1k
Olivier Micheau France	47	7.2k 1.0×	3.8k 0.7×	1.2k 0.8×	1.8k 1.2×	2.2k 1.6×	92	10.0k
Stanley Ching‐Cheng Huang United States	30	4.3k 0.6×	6.8k 1.3×	1.5k 1.0×	1.5k 1.0×	1.9k 1.4×	47	11.5k

Countries citing papers authored by Francis Ka-Ming Chan

Since Specialization

Citations

This map shows the geographic impact of Francis Ka-Ming Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Francis Ka-Ming Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Francis Ka-Ming Chan more than expected).

Fields of papers citing papers by Francis Ka-Ming Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Francis Ka-Ming Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Francis Ka-Ming Chan. The network helps show where Francis Ka-Ming Chan may publish in the future.

Co-authorship network of co-authors of Francis Ka-Ming Chan

This figure shows the co-authorship network connecting the top 25 collaborators of Francis Ka-Ming Chan. A scholar is included among the top collaborators of Francis Ka-Ming Chan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Francis Ka-Ming Chan. Francis Ka-Ming Chan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chan, Francis Ka-Ming, et al.. (2022). Necroptosis at a glance. Journal of Cell Science. 135(17). 7 indexed citations

Rucker, A. Justin & Francis Ka-Ming Chan. (2022). Tumor-intrinsic and immune modulatory roles of receptor-interacting protein kinases. Trends in Biochemical Sciences. 47(4). 342–351. 11 indexed citations

Moriwaki, Kenta, Francis Ka-Ming Chan, & Eiji Miyoshi. (2021). Sweet modification and regulation of death receptor signalling pathway. The Journal of Biochemistry. 169(6). 643–652. 22 indexed citations

Liu, Zhijun & Francis Ka-Ming Chan. (2020). Regulatory mechanisms of RIPK1 in cell death and inflammation. Seminars in Cell and Developmental Biology. 109. 70–75. 29 indexed citations

Yamamoto, Tori N., Anthony Cruz, Francis Ka-Ming Chan, et al.. (2017). Non-apoptotic signaling through Fas activates Akt and promotes T cell differentiation through Caspase-8. The Journal of Immunology. 198(Supplement_1). 217.15–217.15. 1 indexed citations

Moriwaki, Kenta, Sakthi Balaji, John Bertin, Peter J. Gough, & Francis Ka-Ming Chan. (2017). Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair. Cell Reports. 18(10). 2441–2451. 46 indexed citations

Moriwaki, Kenta & Francis Ka-Ming Chan. (2016). Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome. Journal of Biological Chemistry. 291(11). 5948–5959. 55 indexed citations

Moriwaki, Kenta, Sakthi Balaji, & Francis Ka-Ming Chan. (2016). Border Security: The Role of RIPK3 in Epithelium Homeostasis. Frontiers in Cell and Developmental Biology. 4. 70–70. 8 indexed citations

Moriwaki, Kenta, John Bertin, Peter J. Gough, & Francis Ka-Ming Chan. (2015). A RIPK3–Caspase 8 Complex Mediates Atypical Pro–IL-1β Processing. The Journal of Immunology. 194(4). 1938–1944. 142 indexed citations

10.

Moriwaki, Kenta, Nívea F. Luz, Sakthi Balaji, et al.. (2015). The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. The Journal of Immunology. 196(1). 407–415. 104 indexed citations

11.

Polykratis, Apostolos, Nicole Hermance, Matija Zelic, et al.. (2014). Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo. The Journal of Immunology. 193(4). 1539–1543. 259 indexed citations

12.

Upton, Jason W. & Francis Ka-Ming Chan. (2014). Staying Alive: Cell Death in Antiviral Immunity. Molecular Cell. 54(2). 273–280. 129 indexed citations

13.

Moriwaki, Kenta & Francis Ka-Ming Chan. (2013). RIP3: a molecular switch for necrosis and inflammation. Genes & Development. 27(15). 1640–1649. 288 indexed citations

14.

McQuade, Thomas J., YoungSik Cho, & Francis Ka-Ming Chan. (2013). Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis. Biochemical Journal. 456(3). 409–415. 114 indexed citations

15.

Zhang, Haibing, Xiaohui Zhou, Thomas J. McQuade, et al.. (2011). Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature. 471(7338). 373–376. 351 indexed citations

16.

Chan, Francis Ka-Ming, YoungSik Cho, & Sreerupa Challa. (2009). A Role for RIP1/RIP3-Dependent Programmed Necrosis in Innate Immune Responses Against Vaccinia Virus Infections (135.44). The Journal of Immunology. 182(Supplement_1). 135.44–135.44. 1 indexed citations

17.

Challa, Sreerupa, David Moquin, Ryan M. Genga, et al.. (2009). Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation. Cell. 137(6). 1112–1123. 1915 indexed citations breakdown →

18.

Bixby, Jacqueline, et al.. (2006). Transgenic Expression of the Viral FLIP MC159 Causes lpr / gld -Like Lymphoproliferation and Autoimmunity. The Journal of Immunology. 177(6). 3814–3820. 14 indexed citations

19.

Chan, Francis Ka-Ming & Kevin L. Holmes. (2004). Flow Cytometric Analysis of Fluorescence Resonance Energy Transfer: A Tool for High-Throughput Screening of Molecular Interactions in Living Cells. Humana Press eBooks. 263. 281–292. 9 indexed citations

20.

Chan, Francis Ka-Ming & Michael J. Lenardo. (2000). A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes. European Journal of Immunology. 30(2). 652–660. 124 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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