Arie P. Otte

24.8k citations

98 papers · 18.3k indexed · 9 hit papers · h-index 60

Molecular Biology top 0.1%
Genetics top 0.2%
Cancer Research top 0.5%
Oncology top 2%
Pulmonary and Respiratory Medicine top 2%

Co-authors: Richard G. A. B. Sewalt David Satijn Johan van der Vlag Mark A. Rubin Debashis Ghosh Sooryanarayana Varambally Neil Brockdorff Kathrin Plath
Topics: Epigenetics and DNA Methylation (57 papers)Cancer-related gene regulation (44 papers)Genomics and Chromatin Dynamics (25 papers)
Cited by: Molecular Biology Cancer Research Genetics
Journals: Nature Science Cell
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Arie P. Otte

98 papers receiving 18.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The polycomb group protein EZH2 is involved in progression of prostate cancer

2002 2.1k citations Martin G. Sanda, Richard G. A. B. Sewalt et al. Nature profile →
Polycomb complexes repress developmental regulators in murine embryonic stem cells

2006 2.0k citations Arie P. Otte, Miguel Vidal et al. Nature profile →
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

2003 1.3k citations Richard G. A. B. Sewalt, Arie P. Otte et al. profile →
Role of Histone H3 Lysine 27 Methylation in X Inactivation

2003 945 citations Arie P. Otte et al. Science profile →
Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation

2004 728 citations Arie P. Otte, Miguel Vidal et al. profile →
EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometrium, Prostate, and Breast

2005 694 citations Arie P. Otte et al. profile →
Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Development

2003 630 citations Ikuhiro Okamoto, Arie P. Otte et al. Science profile →
Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes

2003 529 citations Arie P. Otte et al. profile →
Reactivation of the Paternal X Chromosome in Early Mouse Embryos

2004 428 citations Arie P. Otte et al. Science profile →

Peers

Countries citing papers authored by Arie P. Otte

Since Specialization

Citations

This map shows the geographic impact of Arie P. Otte's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Arie P. Otte with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Arie P. Otte more than expected).

Fields of papers citing papers by Arie P. Otte

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Arie P. Otte. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Arie P. Otte. The network helps show where Arie P. Otte may publish in the future.

Co-authorship network of co-authors of Arie P. Otte

This figure shows the co-authorship network connecting the top 25 collaborators of Arie P. Otte. A scholar is included among the top collaborators of Arie P. Otte based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Arie P. Otte. Arie P. Otte is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Methods to create a stringent selection system for mammalian cell lines 2011 ·Cytotechnology ·(unknown),(unknown),M. Siep,Arie P. Otte,John Verhees	12
2	Impeding Xist Expression from the Active X Chromosome Improves Mouse Somatic Cell Nuclear Transfer 2010 ·Science ·Kimiko Inoue,Takashi Kohda,Michihiko Sugimoto,Takashi Sado,Narumi Ogonuki,Shogo Matoba,Hirosuke Shiura,Rieko Ikeda,Keiji Mochida,Takashi Fujii,Ken Sawai,Arie P. Otte,Xiuchun Tian,Xiangzhong Yang,Fumitoshi Ishino,Kuniya Abe,Atsuo Ogura	188
3	Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice 2005 ·Nature ·Ikuhiro Okamoto,Danielle Arnaud,Patricia Le Baccon,Arie P. Otte,Christine M. Distèche,Philip Avner,Édith Heard	145
4	X chromosome reactivation and regulation in cloned embryos 2005 ·Developmental Biology ·Leisha D. Nolen,Shaorong Gao,Zhiming Han,Mellissa R.W. Mann,Young Gie Chung,Arie P. Otte,Marisa S. Bartolomei,Keith E. Latham	99
5	The Murine Polycomb Group Protein Eed Is Required for Global Histone H3 Lysine-27 Methylation 2005 ·Current Biology ·Nathan D. Montgomery,Della Yee,Andrew Chen,Sundeep Kalantry,Stormy J. Chamberlain,Arie P. Otte,Terry Magnuson	280
6	Expression of the p16INK4a gene product, methylation of the p16INK4a promoter region and expression of the polycomb-group gene BMI-1 in squamous cell lung carcinoma and premalignant endobronchial lesions 2005 ·Lung Cancer ·R.H.J. Breuer,Peter J.F. Snijders,G. Sutedja,Richard G. A. B. Sewalt,Arie P. Otte,Pieter E. Postmus,Chris J.L.M. Meijer,Frank M. Raaphorst,Egbert F. Smit	48
7	Unique Polycomb Gene Expression Pattern in Hodgkin's Lymphoma and Hodgkin's Lymphoma-Derived Cell Lines 2004 ·American Journal Of Pathology ·Danny F. Dukers,Joost C. van Galen,(unknown),Patty M. Jansen,Richard G. A. B. Sewalt,Arie P. Otte,Hanneke C. Kluin‐Nelemans,Chris J.L.M. Meijer,Frank M. Raaphorst	97
8	Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Developmentbreakdown → 2003 ·Science ·Ikuhiro Okamoto,Arie P. Otte,C. David Allis,Danny Reinberg,Édith Heard	630
9	Biochemical Analysis of Mammalian Polycomb Group Protein Complexes and the Identification of Genetic Elements that Block Polycomb-Mediated Gene Repression 2003 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Richard G. A. B. Sewalt,Ted Kwaks,Karien M. Hamer,Arie P. Otte	6
10	Multiplex Biomarker Approach for Determining Risk of Prostate-Specific Antigen-Defined Recurrence of Prostate Cancer 2003 ·JNCI Journal of the National Cancer Institute ·Daniel R. Rhodes,Martin G. Sanda,Arie P. Otte,AM Chinnaiyan,Mark A. Rubin	213
11	Distinct BMI-1 and EZH2 Expression Patterns in Thymocytes and Mature T Cells Suggest a Role for Polycomb Genes in Human T Cell Differentiation 2001 ·The Journal of Immunology ·Frank M. Raaphorst,Arie P. Otte,Folkert J. van Kemenade,Tjasso Blokzijl,Elly Fieret,Karien M. Hamer,David Satijn,Chris J.L.M. Meijer	62
12	Differential expression of human Polycomb group proteins in various tissues and cell types 2001 ·Journal of Cellular Biochemistry ·Marco J. Gunster,Frank M. Raaphorst,Karien M. Hamer,Jan L. den Blaauwen,Elly Fieret,Chris J.L.M. Meijer,Arie P. Otte	41
13	Cutting Edge: Polycomb Gene Expression Patterns Reflect Distinct B Cell Differentiation Stages in Human Germinal Centers 2000 ·The Journal of Immunology ·Frank M. Raaphorst,Folkert J. van Kemenade,Elly Fieret,Karien M. Hamer,David Satijn,Arie P. Otte,Chris J.L.M. Meijer	82
14	Coexpression of BMI-1 and EZH2 Polycomb Group Genes in Reed-Sternberg Cells of Hodgkin’s Disease 2000 ·American Journal Of Pathology ·Frank M. Raaphorst,Folkert J. van Kemenade,Tjasso Blokzijl,Elly Fieret,Karien M. Hamer,David Satijn,Arie P. Otte,Chris J.L.M. Meijer	138
15	C-Terminal Binding Protein Is a Transcriptional Repressor That Interacts with a Specific Class of Vertebrate Polycomb Proteins 1999 ·Molecular and Cellular Biology ·Richard G. A. B. Sewalt,Marco J. Gunster,Johan van der Vlag,David Satijn,Arie P. Otte	163
16	RING1 Interacts with Multiple Polycomb-Group Proteins and Displays Tumorigenic Activity 1999 ·Molecular and Cellular Biology ·David Satijn,Arie P. Otte	106
17	Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes 1998 ·Molecular and Cellular Biology ·Richard G. A. B. Sewalt,Johan van der Vlag,Marco J. Gunster,Karien M. Hamer,Jan L. den Blaauwen,David Satijn,(unknown),Roel van Driel,Arie P. Otte	196
18	RING1 Is Associated with the Polycomb Group Protein Complex and Acts as a Transcriptional Repressor 1997 ·Molecular and Cellular Biology ·David Satijn,Marco J. Gunster,Johan van der Vlag,Karien M. Hamer,Wouter Schul,Mark J. Alkema,Andrew J. Saurin,Paul S. Freemont,Roel van Driel,Arie P. Otte	164
19	Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain 1997 ·The EMBO Journal ·Jon Schoorlemmer,Camelia V. Marcos-Gutierrez,Felipe Were,Rodrigo M. Maza,(unknown),David Satijn,Arie P. Otte,Miguel Vidal	134
20	[A case of succinylcholine apnea. Identification of genetic variants]. 1979 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·(unknown),(unknown),(unknown),(unknown),Arie P. Otte,(unknown)	1

About Arie P. Otte

Arie P. Otte is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience, having authored 98 papers that have together received 18.3k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (57 papers), Cancer-related gene regulation (44 papers) and Genomics and Chromatin Dynamics (25 papers). The work is most often cited by research in Molecular Biology (16.5k citations), Cancer Research (2.7k citations) and Genetics (3.8k citations). Arie P. Otte has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Richard G. A. B. Sewalt, David Satijn, Johan van der Vlag, Mark A. Rubin, Debashis Ghosh, Sooryanarayana Varambally, Neil Brockdorff, Kathrin Plath, Miguel Vidal and Martin G. Sanda. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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