Arie P. Otte

24.8k total citations · 9 hit papers
98 papers, 18.3k citations indexed

About

Arie P. Otte is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience. According to data from OpenAlex, Arie P. Otte has authored 98 papers receiving a total of 18.3k indexed citations (citations by other indexed papers that have themselves been cited), including 90 papers in Molecular Biology, 22 papers in Genetics and 7 papers in Cellular and Molecular Neuroscience. Recurrent topics in Arie P. Otte's work include Epigenetics and DNA Methylation (57 papers), Cancer-related gene regulation (44 papers) and Genomics and Chromatin Dynamics (25 papers). Arie P. Otte is often cited by papers focused on Epigenetics and DNA Methylation (57 papers), Cancer-related gene regulation (44 papers) and Genomics and Chromatin Dynamics (25 papers). Arie P. Otte collaborates with scholars based in Netherlands, United States and United Kingdom. Arie P. Otte's co-authors include Richard G. A. B. Sewalt, David Satijn, Johan van der Vlag, Mark A. Rubin, Debashis Ghosh, Sooryanarayana Varambally, Neil Brockdorff, Kathrin Plath, Miguel Vidal and Martin G. Sanda and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Arie P. Otte

98 papers receiving 18.1k citations

Hit Papers

The polycomb group protei... 2002 2026 2010 2018 2002 2006 2003 2003 2004 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The polycomb group protein EZH2 is involved in progression of prostate cancer
    2002 2.1k citations Richard G. A. B. Sewalt, Arie P. Otte et al. Nature profile →
  2. Polycomb complexes repress developmental regulators in murine embryonic stem cells
    2006 2.0k citations Laurie A. Boyer, Kathrin Plath et al. Nature profile →
  3. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
    2003 1.3k citations Richard G. A. B. Sewalt, Arie P. Otte et al. profile →
  4. Role of Histone H3 Lysine 27 Methylation in X Inactivation
    2003 945 citations Kathrin Plath, Arie P. Otte et al. Science profile →
  5. Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation
    2004 728 citations José Silva, Arie P. Otte et al. profile →
  6. EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometrium, Prostate, and Breast
    2005 694 citations Arie P. Otte et al. profile →
  7. Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Development
    2003 630 citations Ikuhiro Okamoto, Arie P. Otte et al. Science profile →
  8. Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes
    2003 529 citations José Silva, Winifred Mak et al. profile →
  9. Reactivation of the Paternal X Chromosome in Early Mouse Embryos
    2004 428 citations Winifred Mak, Arie P. Otte et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Arie P. Otte Netherlands 60 16.5k 3.8k 2.7k 1.4k 1.1k 98 18.3k
Thomas W. Glover United States 60 10.3k 0.6× 4.5k 1.2× 1.8k 0.7× 3.6k 2.5× 1.2k 1.1× 159 15.8k
Maarten van Lohuizen Netherlands 73 17.4k 1.1× 2.6k 0.7× 2.4k 0.9× 4.0k 2.8× 756 0.7× 143 20.4k
Peggy Farnham United States 77 17.5k 1.1× 3.7k 1.0× 4.7k 1.7× 3.6k 2.5× 540 0.5× 184 21.1k
Jussi Taipale Finland 61 19.6k 1.2× 4.0k 1.1× 2.4k 0.9× 4.7k 3.3× 1.1k 1.0× 110 24.2k
Joanna Wysocka United States 51 16.6k 1.0× 2.4k 0.6× 2.7k 1.0× 1.1k 0.8× 475 0.4× 112 19.5k
Kathrin Plath United States 60 19.1k 1.2× 3.9k 1.0× 2.3k 0.8× 811 0.6× 316 0.3× 124 21.2k
John K. Cowell United States 57 7.0k 0.4× 1.9k 0.5× 1.6k 0.6× 2.2k 1.6× 908 0.8× 302 11.3k
Peter K. Jackson United States 63 12.6k 0.8× 4.0k 1.1× 934 0.3× 3.4k 2.3× 387 0.4× 204 17.0k
Ad Geurts van Kessel Netherlands 63 8.0k 0.5× 4.8k 1.2× 1.9k 0.7× 2.0k 1.4× 2.9k 2.6× 256 15.6k
Luciano Di Croce Spain 52 10.6k 0.6× 1.9k 0.5× 2.1k 0.8× 1.2k 0.8× 523 0.5× 128 12.7k

Countries citing papers authored by Arie P. Otte

Since Specialization
Citations

This map shows the geographic impact of Arie P. Otte's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Arie P. Otte with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Arie P. Otte more than expected).

Fields of papers citing papers by Arie P. Otte

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Arie P. Otte. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Arie P. Otte. The network helps show where Arie P. Otte may publish in the future.

Co-authorship network of co-authors of Arie P. Otte

This figure shows the co-authorship network connecting the top 25 collaborators of Arie P. Otte. A scholar is included among the top collaborators of Arie P. Otte based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Arie P. Otte. Arie P. Otte is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Inoue, Kimiko, Takashi Kohda, Michihiko Sugimoto, et al.. (2010). Impeding Xist Expression from the Active X Chromosome Improves Mouse Somatic Cell Nuclear Transfer. Science. 330(6003). 496–499. 188 indexed citations
2.
Hoffmann, Michèle J., Rainer Engers, Andrea R. Florl, et al.. (2007). Expression changes in EZH2, but not in BMI-1, SIRT1, DNMT1 or DNMT3B are associated with DNA methylation changes in prostate cancer. Cancer Biology & Therapy. 6(9). 1399–1408. 69 indexed citations
3.
Kwaks, Ted & Arie P. Otte. (2006). Employing epigenetics to augment the expression of therapeutic proteins in mammalian cells. Trends in biotechnology. 24(3). 137–142. 88 indexed citations
4.
Boyer, Laurie A., Kathrin Plath, Julia Zeitlinger, et al.. (2006). Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 441(7091). 349–353. 1998 indexed citations breakdown →
5.
Okamoto, Ikuhiro, Danielle Arnaud, Patricia Le Baccon, et al.. (2005). Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice. Nature. 438(7066). 369–373. 145 indexed citations
6.
Cha, Tai-Lung, Binhua P. Zhou, Weiya Xia, et al.. (2005). Akt-Mediated Phosphorylation of EZH2 Suppresses Methylation of Lysine 27 in Histone H3. Science. 310(5746). 306–310. 447 indexed citations
7.
Dukers, Danny F., Joost C. van Galen, Patty M. Jansen, et al.. (2004). Unique Polycomb Gene Expression Pattern in Hodgkin's Lymphoma and Hodgkin's Lymphoma-Derived Cell Lines. American Journal Of Pathology. 164(3). 873–881. 97 indexed citations
8.
Okamoto, Ikuhiro, Arie P. Otte, C. David Allis, Danny Reinberg, & Édith Heard. (2003). Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Development. Science. 303(5658). 644–649. 630 indexed citations breakdown →
9.
Sewalt, Richard G. A. B., Ted Kwaks, Karien M. Hamer, & Arie P. Otte. (2003). Biochemical Analysis of Mammalian Polycomb Group Protein Complexes and the Identification of Genetic Elements that Block Polycomb-Mediated Gene Repression. Methods in enzymology on CD-ROM/Methods in enzymology. 377. 282–296. 6 indexed citations
10.
Mak, Winifred, et al.. (2002). Mitotically Stable Association of Polycomb Group Proteins Eed and Enx1 with the Inactive X Chromosome in Trophoblast Stem Cells. Current Biology. 12(12). 1016–1020. 181 indexed citations
11.
Raaphorst, Frank M., Arie P. Otte, Folkert J. van Kemenade, et al.. (2001). Distinct BMI-1 and EZH2 Expression Patterns in Thymocytes and Mature T Cells Suggest a Role for Polycomb Genes in Human T Cell Differentiation. The Journal of Immunology. 166(10). 5925–5934. 62 indexed citations
12.
Gunster, Marco J., Frank M. Raaphorst, Karien M. Hamer, et al.. (2001). Differential expression of human Polycomb group proteins in various tissues and cell types. Journal of Cellular Biochemistry. 81(S36). 129–143. 41 indexed citations
13.
Raaphorst, Frank M., Folkert J. van Kemenade, Elly Fieret, et al.. (2000). Cutting Edge: Polycomb Gene Expression Patterns Reflect Distinct B Cell Differentiation Stages in Human Germinal Centers. The Journal of Immunology. 164(1). 1–4. 82 indexed citations
14.
Raaphorst, Frank M., Folkert J. van Kemenade, Tjasso Blokzijl, et al.. (2000). Coexpression of BMI-1 and EZH2 Polycomb Group Genes in Reed-Sternberg Cells of Hodgkin’s Disease. American Journal Of Pathology. 157(3). 709–715. 138 indexed citations
15.
Satijn, David & Arie P. Otte. (1999). RING1 Interacts with Multiple Polycomb-Group Proteins and Displays Tumorigenic Activity. Molecular and Cellular Biology. 19(1). 57–68. 106 indexed citations
16.
Sewalt, Richard G. A. B., Marco J. Gunster, Johan van der Vlag, David Satijn, & Arie P. Otte. (1999). C-Terminal Binding Protein Is a Transcriptional Repressor That Interacts with a Specific Class of Vertebrate Polycomb Proteins. Molecular and Cellular Biology. 19(1). 777–787. 163 indexed citations
17.
Sewalt, Richard G. A. B., Johan van der Vlag, Marco J. Gunster, et al.. (1998). Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes. Molecular and Cellular Biology. 18(6). 3586–3595. 196 indexed citations
18.
Olson, Daniel J., Mitsuo Oshimura, Arie P. Otte, & Rakesh Kumar. (1998). Ectopic Expression of <i>wnt</i>-5a in Human Renal Cell Carcinoma Cells Suppresses in vitro Growth and Telomerase Activity. Tumor Biology. 19(4). 244–252. 21 indexed citations
19.
Satijn, David, Marco J. Gunster, Johan van der Vlag, et al.. (1997). RING1 Is Associated with the Polycomb Group Protein Complex and Acts as a Transcriptional Repressor. Molecular and Cellular Biology. 17(7). 4105–4113. 164 indexed citations
20.
Otte, Arie P., et al.. (1979). [A case of succinylcholine apnea. Identification of genetic variants].. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 20(2). 109–12. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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