Peter W. Lewis

10.3k citations

53 papers · 4.8k indexed · 3 hit papers · h-index 27

Molecular Biology top 2%
Genetics top 1%
Oncology top 5%
Genetics top 5%
Cancer Research top 5%

Co-authors: C. David Allis Michael R. Botchan Kyung‐Min Noh Laura A. Banaszynski Tom W. Muir Simon J. Elsaesser Sonja C. Stadler Manuel M. Müller
Topics: Epigenetics and DNA Methylation (25 papers)Genomics and Chromatin Dynamics (15 papers)RNA modifications and cancer (12 papers)
Cited by: Genetics Molecular Biology Aging
Journals: Nature Science Cell
Partner nations: United States Canada United Kingdom

In The Last Decade

Peter W. Lewis

51 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

2013 898 citations Peter W. Lewis, Manuel M. Müller et al. Science profile →
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

2010 631 citations Peter W. Lewis, Kyung‐Min Noh et al. Proceedings of the National Academy of Sciences profile →
Isolation of the Cdc45/Mcm2–7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

2006 541 citations Peter W. Lewis, Michael R. Botchan et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Peter W. Lewis

Since Specialization

Citations

This map shows the geographic impact of Peter W. Lewis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter W. Lewis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter W. Lewis more than expected).

Fields of papers citing papers by Peter W. Lewis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter W. Lewis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter W. Lewis. The network helps show where Peter W. Lewis may publish in the future.

Co-authorship network of co-authors of Peter W. Lewis

This figure shows the co-authorship network connecting the top 25 collaborators of Peter W. Lewis. A scholar is included among the top collaborators of Peter W. Lewis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Peter W. Lewis. Peter W. Lewis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pioneer-factor activity requires stable chromatin occupancy mediated by both sequence-specific binding and disordered protein domains 2026 ·bioRxiv (Cold Spring Harbor Laboratory) ·(unknown),(unknown),(unknown),(unknown),Charalambos Roussos,(unknown),Andrew Q. Rashoff,(unknown),Peter W. Lewis,Sarah J. Bray,Melissa M. Harrison	1
2	Novel modifiers of oncoprotein-mediated Polycomb inhibition in Drosophila melanogaster 2025 ·Genetics ·(unknown),(unknown),(unknown),J. Truman,Siddhant U. Jain,Peter W. Lewis,Melissa M. Harrison	0
3	Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing 2024 ·Nature Communications ·(unknown),(unknown),(unknown),Peter W. Lewis	7
4	Abstract A060: Genetic alterations induce distinct histone post-translational modifications during the transition to castration-resistant prostate cancer 2023 ·Cancer Research ·Tanaya A. Purohit,Joseph Gawdzik,Bing Yang,Eric A. Armstrong,Peter W. Lewis,John M. Denu,David F. Jarrard	1
5	Human spliceosomal snRNA sequence variants generate variant spliceosomes 2021 ·RNA ·(unknown),Peter W. Lewis,David A. Brow,Heidi Dvinge	19
6	Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression 2020 ·Proceedings of the National Academy of Sciences ·Siddhant U. Jain,Sima Khazaei,Dylan M. Marchione,Stefan Lundgren,Xiaoshi Wang,Daniel N. Weinberg,Shriya Deshmukh,Nikoleta Juretic,Chao Lü,C. David Allis,Benjamin A. García,Nada Jabado,Peter W. Lewis	70
7	H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2 2020 ·Molecular Cell ·Siddhant U. Jain,Andrew Q. Rashoff,(unknown),Dominik Hoelper,J. Truman,Tyler J. Gibson,Stefan Lundgren,Eliana R. Bondra,Shriya Deshmukh,Ashot S. Harutyunyan,Nikoleta Juretic,Nada Jabado,Melissa M. Harrison,Peter W. Lewis	94
8	Continued Activity of the Pioneer Factor Zelda Is Required to Drive Zygotic Genome Activation 2019 ·Molecular Cell ·Stephen L. McDaniel,Tyler J. Gibson,Katharine N. Schulz,Meilín Fernández García,(unknown),Siddhant U. Jain,Peter W. Lewis,Kenneth S. Zaret,Melissa M. Harrison	78
9	S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability of cancer stem cells 2019 ·Breast Cancer Research and Treatment ·Elena Strekalova,Dmitry Malin,(unknown),Jason D. Russell,Dominik Hoelper,Aayushi Jain,Joshua J. Coon,Peter W. Lewis,Vincent L. Cryns	64
10	Recognition of cancer mutations in histone H3K36 by epigenetic writers and readers 2018 ·Epigenetics ·Brianna J. Klein,Krzysztof Krajewski,(unknown),Peter W. Lewis,Brian D. Strahl,Tatiana G. Kutateladze	17
11	Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX 2017 ·Nature Communications ·Dominik Hoelper,Hongda Huang,Aayushi Jain,Dinshaw J. Patel,Peter W. Lewis	79
12	Targeted Histone Peptides: Insights into the Spatial Regulation of the Methyltransferase PRC2 by using a Surrogate of Heterotypic Chromatin 2015 ·Angewandte Chemie International Edition ·Zachary Z. Brown,Manuel M. Müller,Ha Eun Kong,Peter W. Lewis,Tom W. Muir	14
13	ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons 2014 ·Proceedings of the National Academy of Sciences ·Kyung‐Min Noh,Ian Maze,Dan Zhao,Bin Xiang,Wendy Wenderski,Peter W. Lewis,Li Shen,Haitao Li,C. David Allis	43
14	A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas 2014 ·Acta Neuropathologica ·Sriram Venneti,Mariarita Santi,Michelle M. Felicella,Dmitry Yarilin,Joanna J. Phillips,Lisa Sullivan,Daniel Martínez,Arie Perry,Peter W. Lewis,Craig B. Thompson,Alexander R. Judkins	102
15	Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastomabreakdown → 2013 ·Science ·Peter W. Lewis,Manuel M. Müller,(unknown),Francisco J. Cordero,Shu Lin,Laura A. Banaszynski,Benjamin A. Garcia,Tom W. Muir,Oren J. Becher,C. David Allis	898
16	DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition 2012 ·Nature ·Simon J. Elsässer,Hongda Huang,Peter W. Lewis,Jason W. Chin,C. David Allis,Dinshaw J. Patel	191
17	ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome 2011 ·Nature Structural & Molecular Biology ·Shigeki Iwase,Bin Xiang,Sharmistha Ghosh,Ting Ren,Peter W. Lewis,Jesse C. Cochrane,C. David Allis,David J. Picketts,Dinshaw J. Patel,Haitao Li,Yang Shi	205
18	Discovery of tMAC: a Drosophila testis-specific meiotic arrest complex paralogous to Myb–Muv B 2007 ·Genes & Development ·Eileen L. Beall,Peter W. Lewis,Maren Bell,(unknown),D. Leanne Jones,Michael R. Botchan	74
19	Isolation of the Cdc45/Mcm2–7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicasebreakdown → 2006 ·Proceedings of the National Academy of Sciences ·(unknown),Peter W. Lewis,Michael R. Botchan	541
20	Modern criminal justice 1978 ·McGraw-Hill eBooks ·Jack C. Wright,Peter W. Lewis	1

About Peter W. Lewis

Peter W. Lewis is a scholar working on Molecular Biology, Genetics and Cancer Research, having authored 53 papers that have together received 4.8k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (25 papers), Genomics and Chromatin Dynamics (15 papers) and RNA modifications and cancer (12 papers). The work is most often cited by research in Genetics (920 citations), Molecular Biology (3.9k citations) and Aging (69 citations). Peter W. Lewis has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include C. David Allis, Michael R. Botchan, Kyung‐Min Noh, Laura A. Banaszynski, Tom W. Muir, Simon J. Elsaesser, Sonja C. Stadler, Manuel M. Müller, Benjamin A. Garcia and Oren J. Becher. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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