Leonard D. Shultz

43.4k total citations · 12 hit papers
452 papers, 32.2k citations indexed

About

Leonard D. Shultz is a scholar working on Immunology, Molecular Biology and Genetics. According to data from OpenAlex, Leonard D. Shultz has authored 452 papers receiving a total of 32.2k indexed citations (citations by other indexed papers that have themselves been cited), including 241 papers in Immunology, 119 papers in Molecular Biology and 86 papers in Genetics. Recurrent topics in Leonard D. Shultz's work include Immune Cell Function and Interaction (108 papers), T-cell and B-cell Immunology (83 papers) and Immunotherapy and Immune Responses (64 papers). Leonard D. Shultz is often cited by papers focused on Immune Cell Function and Interaction (108 papers), T-cell and B-cell Immunology (83 papers) and Immunotherapy and Immune Responses (64 papers). Leonard D. Shultz collaborates with scholars based in United States, Japan and United Kingdom. Leonard D. Shultz's co-authors include Dale L. Greiner, Michael A. Brehm, Fumihiko Ishikawa, Edward H. Leiter, Bruce Gott, Bonnie Lyons, T. V. Rajan, Sherri W. Christianson, Lisa Burzenski and Hisahiro Yoshida and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Leonard D. Shultz

448 papers receiving 31.7k citations

Hit Papers

The murine mutation osteopetrosis is in the coding region... 1990 2026 2002 2014 1990 1999 2005 1995 2007 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
    1990 1.4k citations Leonard D. Shultz et al. profile →
  2. Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4
    1999 1.4k citations Leonard D. Shultz et al. profile →
  3. Human Lymphoid and Myeloid Cell Development in NOD/LtSz- scid IL2R γ null Mice Engrafted with Mobilized Human Hemopoietic Stem Cells,
    2005 1.3k citations Leonard D. Shultz, Lisa Burzenski et al. profile →
  4. Multiple defects in innate and adaptive immunologic function in NOD/LtSz- scid mice.
    1995 972 citations Leonard D. Shultz, Dale L. Greiner et al. profile →
  5. Humanized mice in translational biomedical research
    2007 963 citations Leonard D. Shultz, Dale L. Greiner et al. profile →
  6. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice
    2005 733 citations Leonard D. Shultz et al. profile →
  7. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
    2007 717 citations Leonard D. Shultz et al. profile →
  8. Humanized mice for immune system investigation: progress, promise and challenges
    2012 692 citations Leonard D. Shultz, Michael A. Brehm et al. profile →
  9. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.
    1996 502 citations Leonard D. Shultz et al. profile →
  10. Humanized Mouse Models of Clinical Disease
    2016 409 citations Sonal Jangalwe, Dale L. Greiner et al. profile →
  11. Humanized mouse models for immuno-oncology research
    2023 212 citations Dale L. Greiner, James Keck et al. profile →
  12. Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
    2022 144 citations Zheng Gong, Jiayuan Shi et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Leonard D. Shultz United States 92 14.0k 10.5k 7.9k 5.4k 4.8k 452 32.2k
Herman Waldmann United Kingdom 105 22.3k 1.6× 6.9k 0.7× 5.4k 0.7× 3.6k 0.7× 5.8k 1.2× 539 36.5k
Hal E. Broxmeyer United States 89 12.3k 0.9× 10.1k 1.0× 9.6k 1.2× 2.4k 0.4× 9.6k 2.0× 570 30.4k
Olivier Hermine France 90 11.9k 0.9× 7.1k 0.7× 6.3k 0.8× 2.2k 0.4× 3.8k 0.8× 822 29.8k
Thomas F. Tedder United States 113 26.9k 1.9× 8.0k 0.8× 7.0k 0.9× 2.5k 0.5× 2.6k 0.5× 342 41.1k
Frédéric J. de Sauvage United States 86 6.5k 0.5× 17.7k 1.7× 8.0k 1.0× 4.7k 0.9× 2.8k 0.6× 148 31.0k
Steven Μ. Albelda United States 96 13.6k 1.0× 10.6k 1.0× 13.2k 1.7× 4.1k 0.8× 2.3k 0.5× 315 35.5k
Eugene C. Butcher United States 126 31.9k 2.3× 12.4k 1.2× 10.2k 1.3× 2.7k 0.5× 4.3k 0.9× 338 53.4k
Ulrich H. von Andrian United States 109 26.1k 1.9× 9.8k 0.9× 7.6k 1.0× 1.9k 0.4× 4.2k 0.9× 256 42.9k
Hiromitsu Nakauchi Japan 87 8.2k 0.6× 15.2k 1.4× 5.4k 0.7× 3.0k 0.6× 8.1k 1.7× 496 30.3k
Koichi Akashi Japan 83 12.0k 0.9× 11.6k 1.1× 6.2k 0.8× 1.6k 0.3× 10.0k 2.1× 680 29.8k

Countries citing papers authored by Leonard D. Shultz

Since Specialization
Citations

This map shows the geographic impact of Leonard D. Shultz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leonard D. Shultz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leonard D. Shultz more than expected).

Fields of papers citing papers by Leonard D. Shultz

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leonard D. Shultz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leonard D. Shultz. The network helps show where Leonard D. Shultz may publish in the future.

Co-authorship network of co-authors of Leonard D. Shultz

This figure shows the co-authorship network connecting the top 25 collaborators of Leonard D. Shultz. A scholar is included among the top collaborators of Leonard D. Shultz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leonard D. Shultz. Leonard D. Shultz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hasanali, Zainul S., Alfred L. Garfall, Lisa Burzenski, et al.. (2024). Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice. JCI Insight. 9(10). 3 indexed citations
2.
Karlinsey, Joyce E., Stephen J. Libby, Dennis C. Ko, et al.. (2024). Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages. mBio. 15(4). e0045424–e0045424. 5 indexed citations
3.
Gong, Zheng, Jiayuan Shi, Peishan Li, et al.. (2023). Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis. Science Immunology. 8(80). eadd5204–eadd5204. 68 indexed citations
4.
Shultz, Leonard D., James Keck, Lisa Burzenski, et al.. (2019). Humanized mouse models of immunological diseases and precision medicine. Mammalian Genome. 30(5-6). 123–142. 78 indexed citations
5.
Akkina, Ramesh, Atef Allam, Alejandro B. Balazs, et al.. (2015). Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary. AIDS Research and Human Retroviruses. 32(2). 109–119. 52 indexed citations
6.
Hosur, Vishnu, Kenneth R. Johnson, Lisa Burzenski, et al.. (2014). Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin. Proceedings of the National Academy of Sciences. 111(21). 46 indexed citations
7.
Trabucco, Sally E., Rachel M. Gerstein, Andrew M. Evens, et al.. (2014). Inhibition of Bromodomain Proteins for the Treatment of Human Diffuse Large B-cell Lymphoma. Clinical Cancer Research. 21(1). 113–122. 116 indexed citations
8.
Ippolito, Gregory C., Kam Hon Hoi, Sai T. Reddy, et al.. (2012). Antibody Repertoires in Humanized NOD-scid-IL2Rγnull Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse. PLoS ONE. 7(4). e35497–e35497. 54 indexed citations
9.
Greiner, Dale L., Michael A. Brehm, Vishnu Hosur, et al.. (2011). Humanized mice for the study of type 1 and type 2 diabetes. Annals of the New York Academy of Sciences. 1245(1). 55–58. 26 indexed citations
10.
Shultz, Leonard D., Michael A. Brehm, Sina Bavari, & Dale L. Greiner. (2011). Humanized mice as a preclinical tool for infectious disease and biomedical research. Annals of the New York Academy of Sciences. 1245(1). 50–54. 51 indexed citations
11.
Moriceau, Gatien, Benjamin Ory, Laura Mitrofan, et al.. (2010). Zoledronic Acid Potentiates mTOR Inhibition and Abolishes the Resistance of Osteosarcoma Cells to RAD001 (Everolimus): Pivotal Role of the Prenylation Process. Cancer Research. 70(24). 10329–10339. 74 indexed citations
12.
Libby, Stephen J., Michael A. Brehm, Dale L. Greiner, et al.. (2010). Humanized nonobese diabetic- scid IL2rγ null mice are susceptible to lethal Salmonella Typhi infection. Proceedings of the National Academy of Sciences. 107(35). 15589–15594. 98 indexed citations
13.
Racki, Waldemar J., Laurence Covassin, Michael A. Brehm, et al.. (2010). NOD-scid IL2rγnull Mouse Model of Human Skin Transplantation and Allograft Rejection. Transplantation. 89(5). 527–536. 57 indexed citations
14.
Yang, Hyuna, Benjamin E. Low, Abhijit Guha, et al.. (2008). Cancer Stem Cells Are Enriched in the Side Population Cells in a Mouse Model of Glioma. Cancer Research. 68(24). 10051–10059. 122 indexed citations
15.
Jaeschke, Anja, Mercedes Rincón, Judith Reilly, et al.. (2005). Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proceedings of the National Academy of Sciences. 102(19). 6931–6935. 74 indexed citations
16.
Schwarze, Jürgen, Grzegorz Cieslewicz, Anthony Joetham, et al.. (2000). Critical Roles for Interleukin-4 and Interleukin-5 during Respiratory Syncytial Virus Infection in the Development of Airway Hyperresponsiveness after Airway Sensitization. American Journal of Respiratory and Critical Care Medicine. 162(2). 380–386. 67 indexed citations
17.
Umeda, Syuji, Wesley G. Beamer, Katsumasa Takagi, et al.. (1999). Deficiency of SHP-1 Protein-Tyrosine Phosphatase Activity Results in Heightened Osteoclast Function and Decreased Bone Density. American Journal Of Pathology. 155(1). 223–233. 61 indexed citations
18.
Patel, Vishal, et al.. (1996). Effect of the mouse scid mutation on meiotic recombination. Mammalian Genome. 7(7). 497–500. 1 indexed citations
19.
Sundberg, J P, T. Burnstein, Leonard D. Shultz, & H G Bedigian. (1989). Identification of Pneumocystis carinii in immunodeficient mice.. PubMed. 39(3). 213–8. 14 indexed citations
20.
Shultz, Leonard D., et al.. (1976). Motheaten, an immunodeficient mutant of the mouse. II. Depressed immune competence and elevated serum immunoglobulins.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 116(4). 936–43. 145 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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