Paul K. Brindle

12.0k citations

54 papers · 8.3k indexed · 7 hit papers · h-index 36

Molecular Biology top 1%
Genetics top 1%
Oncology top 2%
Cellular and Molecular Neuroscience top 2%
Immunology top 2%

Co-authors: Marc Montminy Lawryn H. Kasper Fayçal Boussouar James R. Feramisco Michael Karin Arthur S. Alberts Wu Xu David C. Bedford
Topics: Epigenetics and DNA Methylation (10 papers)Ubiquitin and proteasome pathways (9 papers)Cancer-related gene regulation (9 papers)
Cited by: Molecular Biology Aging Cellular and Molecular Neuroscience
Journals: Nature Cell Proceedings of the National Academy of Sciences
Partner nations: United States Japan United Kingdom

In The Last Decade

Paul K. Brindle

54 papers receiving 8.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

2005 815 citations Seung‐Hoi Koo, Lawrence Flechner et al. Nature profile →
Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation

2007 658 citations Christopher G. Vecsey, Joshua D. Hawk et al. Journal of Neuroscience profile →
Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 651 citations Jonathan Arias, Paul K. Brindle et al. Nature profile →
Inactivating mutations of acetyltransferase genes in B-cell lymphoma

2011 644 citations Laura Pasqualucci, Lawryn H. Kasper et al. Nature profile →
Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation

2010 619 citations Qihuang Jin, Li‐Rong Yu et al. The EMBO Journal profile →
CREBBP mutations in relapsed acute lymphoblastic leukaemia

2011 433 citations Lawryn H. Kasper, Stephanie Lerach et al. Nature profile →
Coupling of Hormonal Stimulation and Transcription via the Cyclic AMP-Responsive Factor CREB Is Rate Limited by Nuclear Entry of Protein Kinase A

1993 354 citations Paul K. Brindle, Robert Armstrong et al. Molecular and Cellular Biology profile →

Peers

Countries citing papers authored by Paul K. Brindle

Since Specialization

Citations

This map shows the geographic impact of Paul K. Brindle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul K. Brindle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul K. Brindle more than expected).

Fields of papers citing papers by Paul K. Brindle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul K. Brindle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul K. Brindle. The network helps show where Paul K. Brindle may publish in the future.

Co-authorship network of co-authors of Paul K. Brindle

This figure shows the co-authorship network connecting the top 25 collaborators of Paul K. Brindle. A scholar is included among the top collaborators of Paul K. Brindle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul K. Brindle. Paul K. Brindle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma 2017 ·Cancer Discovery ·Jiyuan Zhang,Sofija Vlasevska,Victoria A. Wells,Sarah Nataraj,Antony B. Holmes,Romain Duval,Stefanie N. Meyer,Tongwei Mo,Katia Basso,Paul K. Brindle,Shafinaz Hussein,Riccardo Dalla‐Favera,Laura Pasqualucci	151
2	Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation 2014 ·Proceedings of the National Academy of Sciences ·José C. Paz,Sang‐Ho Park,(unknown),Shigenobu Matsumura,Wen‐Wei Tsai,Lawryn H. Kasper,Paul K. Brindle,Guangtao Zhang,Ming‐Ming Zhou,Peter E. Wright,Marc Montminy	24
3	Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity 2013 ·Nature Medicine ·Yujie Liu,Liqing Wang,Jarrod D. Predina,Rongxiang Han,Ulf H. Beier,(unknown),Veena Kapoor,Tricia Bhatti,Tatiana Akimova,Sunil Singhal,Paul K. Brindle,Philip A. Cole,Steven Μ. Albelda,Wayne W. Hancock	161
4	Is histone acetylation the most important physiological function for CBP and p300? 2012 ·Aging ·David C. Bedford,Paul K. Brindle	98
5	Disrupting the CH1 Domain Structure in the Acetyltransferases CBP and p300 Results in Lean Mice with Increased Metabolic Control 2011 ·Cell Metabolism ·David C. Bedford,Lawryn H. Kasper,Ruoning Wang,Yunchao Chang,Douglas R. Green,Paul K. Brindle	33
6	Double null cells reveal that CBP and p300 are dispensable for p53 targetsp21andMdm2but variably required for target genes of other signaling pathways 2011 ·Cell Cycle ·Lawryn H. Kasper,Mary C. Thomas,Gerard P. Zambetti,Paul K. Brindle	26
7	Subregion-specific p300 conditional knock-out mice exhibit long-term memory impairments 2011 ·Learning & Memory ·Ana M.M. Oliveira,(unknown),Joshua D. Hawk,(unknown),Paul K. Brindle,Ted Abel	84
8	Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases 2010 ·Epigenetics ·David C. Bedford,Lawryn H. Kasper,Tomofusa Fukuyama,Paul K. Brindle	231
9	Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivationbreakdown → 2010 ·The EMBO Journal ·Qihuang Jin,Li‐Rong Yu,Lifeng Wang,Zhijing Zhang,Lawryn H. Kasper,Ji‐Eun Lee,Chaochen Wang,Paul K. Brindle,Sharon Dent,Kai Ge	619
10	Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activationbreakdown → 2007 ·Journal of Neuroscience ·Christopher G. Vecsey,Joshua D. Hawk,K. Matthew Lattal,Joel M. Stein,Sara Fabian,Michelle A. Attner,Sonia Cabrera,Conor McDonough,Paul K. Brindle,Ted Abel,Marcelo A. Wood	658
11	Individual CREB‐target genes dictate usage of distinct cAMP‐responsive coactivation mechanisms 2007 ·The EMBO Journal ·Wu Xu,Lawryn H. Kasper,Stephanie Lerach,Trushar Jeevan,Paul K. Brindle	110
12	A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes 2006 ·Learning & Memory ·Marcelo A. Wood,Michelle A. Attner,Ana M.M. Oliveira,Paul K. Brindle,Ted Abel	158
13	Two transactivation mechanisms cooperate for the bulk of HIF‐1‐responsive gene expression 2005 ·The EMBO Journal ·Lawryn H. Kasper,Fayçal Boussouar,Kelli L. Boyd,Wu Xu,(unknown),Jerold E. Rehg,Troy A. Baudino,John L. Cleveland,Paul K. Brindle	125
14	The CREB coactivator TORC2 is a key regulator of fasting glucose metabolismbreakdown → 2005 ·Nature ·Seung‐Hoi Koo,Lawrence Flechner,Ling Qi,Xinmin Zhang,Robert A. Screaton,Shawn Jeffries,Susan Hedrick,Wu Xu,Fayçal Boussouar,Paul K. Brindle,Hiroshi Takemori,Marc Montminy	815
15	A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis 2002 ·Nature ·Lawryn H. Kasper,Fayçal Boussouar,Paul A. Ney,Carl W. Jackson,Jerold E. Rehg,Jan M. van Deursen,Paul K. Brindle	154
16	CREB Binding Protein Interacts with Nucleoporin-Specific FG Repeats That Activate Transcription and Mediate NUP98-HOXA9 Oncogenicity 1999 ·Molecular and Cellular Biology ·Lawryn H. Kasper,Paul K. Brindle,Catherine A. Schnabel,Colin E.J. Pritchard,Michael L. Cleary,Jan M. A. van Deursen	271
17	Regulation of somatostatin gene transcription by cyclic adenosine monophosphate 1996 ·Metabolism ·Marc Montminy,Paul K. Brindle,Jonathan Arias,Kevin Ferreri,Robert Armstrong	24
18	Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressers 1993 ·Nature ·Paul K. Brindle,(unknown),Marc Montminy	150
19	The CREB family of transcription activators 1992 ·Current Opinion in Genetics & Development ·Paul K. Brindle,Marc Montminy	259
20	Sequences within an Upstream Activation Site in the Yeast Enolase Gene EN02 Modulate Repression of EN02 Expression in Strains Carrying a Null Mutation in the Positive Regulatory Gene GCR1 1990 ·Molecular and Cellular Biology ·Janice P. Holland,Paul K. Brindle,Michael J. Holland	8

About Paul K. Brindle

Paul K. Brindle is a scholar working on Molecular Biology, Genetics and Cell Biology, having authored 54 papers that have together received 8.3k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (10 papers), Ubiquitin and proteasome pathways (9 papers) and Cancer-related gene regulation (9 papers). The work is most often cited by research in Molecular Biology (6.0k citations), Aging (102 citations) and Cellular and Molecular Neuroscience (955 citations). Paul K. Brindle has collaborated with scholars based in United States, Japan and United Kingdom. Frequent co-authors include Marc Montminy, Lawryn H. Kasper, Fayçal Boussouar, James R. Feramisco, Michael Karin, Arthur S. Alberts, Wu Xu, David C. Bedford, Ted Abel and Masatoshi Hagiwara. Their work appears in journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact