Ashley V. Menk

7.1k total citations · 6 hit papers
34 papers, 4.6k citations indexed

About

Ashley V. Menk is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Ashley V. Menk has authored 34 papers receiving a total of 4.6k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Immunology, 17 papers in Oncology and 9 papers in Molecular Biology. Recurrent topics in Ashley V. Menk's work include Immune Cell Function and Interaction (15 papers), Cancer Immunotherapy and Biomarkers (11 papers) and CAR-T cell therapy research (9 papers). Ashley V. Menk is often cited by papers focused on Immune Cell Function and Interaction (15 papers), Cancer Immunotherapy and Biomarkers (11 papers) and CAR-T cell therapy research (9 papers). Ashley V. Menk collaborates with scholars based in United States, China and Australia. Ashley V. Menk's co-authors include Greg M. Delgoffe, Nicole E. Scharping, Ryan D. Whetstone, Amanda C. Poholek, Kristin DePeaux, Natalie Rittenhouse, Xue Zeng, Stacy G. Wendell, Paolo Vignali and Rebecca S. Moreci and has published in prestigious journals such as Nature, Journal of Clinical Investigation and The Journal of Experimental Medicine.

In The Last Decade

Ashley V. Menk

33 papers receiving 4.6k citations

Hit Papers

Metabolic support of tumour-infiltrating re... 2016 2026 2019 2022 2021 2016 2021 2016 2018 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Metabolic support of tumour-infiltrating regulatory T cells by lactic acid
    2021 817 citations McLane J. Watson, Paolo Vignali et al. Nature profile →
  2. The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
    2016 562 citations Nicole E. Scharping, Ashley V. Menk et al. Immunity profile →
  3. Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion
    2021 548 citations Nicole E. Scharping, Dayana B. Rivadeneira et al. Nature Immunology profile →
  4. Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia
    2016 399 citations Nicole E. Scharping, Ashley V. Menk et al. Cancer Immunology Research profile →
  5. Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions
    2018 343 citations Ashley V. Menk, Nicole E. Scharping et al. Cell Reports profile →
  6. Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity
    2022 163 citations Paolo Vignali, Kristin DePeaux et al. Nature Immunology profile →

Peers

Ashley V. Menk
Matthew M. Gubin United States
Rahul Roychoudhuri United Kingdom
Viktor Umansky Germany
Meriem Hasmim France
Damya Laoui Belgium
Lukas J.A.C. Hawinkels Netherlands
Nicole E. Scharping United States
Linda Vatan United States
Sabina Sangaletti Italy
Stefano Ugel Italy
Matthew M. Gubin United States
Ashley V. Menk
Citations per year, relative to Ashley V. Menk Ashley V. Menk (= 1×) peers Matthew M. Gubin

Countries citing papers authored by Ashley V. Menk

Since Specialization
Citations

This map shows the geographic impact of Ashley V. Menk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ashley V. Menk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ashley V. Menk more than expected).

Fields of papers citing papers by Ashley V. Menk

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ashley V. Menk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ashley V. Menk. The network helps show where Ashley V. Menk may publish in the future.

Co-authorship network of co-authors of Ashley V. Menk

This figure shows the co-authorship network connecting the top 25 collaborators of Ashley V. Menk. A scholar is included among the top collaborators of Ashley V. Menk based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ashley V. Menk. Ashley V. Menk is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Burr, Ansen B.P., Junyi Ji, Onur Eskiocak, et al.. (2023). Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage. Cellular and Molecular Gastroenterology and Hepatology. 16(2). 287–316. 15 indexed citations
2.
Lontos, Konstantinos, Yiyang Wang, Andrew Frisch, et al.. (2023). Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors. Journal for ImmunoTherapy of Cancer. 11(3). e006522–e006522. 59 indexed citations
3.
Vignali, Paolo, Kristin DePeaux, McLane J. Watson, et al.. (2022). Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity. Nature Immunology. 24(2). 267–279. 163 indexed citations breakdown →
4.
Watson, McLane J., Paolo Vignali, Steven J. Mullett, et al.. (2021). Metabolic support of tumour-infiltrating regulatory T cells by lactic acid. Nature. 591(7851). 645–651. 817 indexed citations breakdown →
5.
Scharping, Nicole E., Dayana B. Rivadeneira, Ashley V. Menk, et al.. (2021). Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion. Nature Immunology. 22(2). 205–215. 548 indexed citations breakdown →
6.
Menk, Ashley V. & Greg M. Delgoffe. (2021). Analyzing Melanoma Cell Oxygen Consumption and Extracellular Acidification Rates Using Seahorse Technology. Methods in molecular biology. 2265. 81–89. 1 indexed citations
7.
Santos, P.M.L., Ashley V. Menk, Jian Shi, et al.. (2019). Tumor-Derived α-Fetoprotein Suppresses Fatty Acid Metabolism and Oxidative Phosphorylation in Dendritic Cells. Cancer Immunology Research. 7(6). 1001–1012. 52 indexed citations
8.
Shao, Lulu, Weizhou Hou, Nicole E. Scharping, et al.. (2019). IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell. Cancer Immunology Research. 7(8). 1258–1266. 52 indexed citations
9.
Beppu, Lisa, Ashley V. Menk, Callen T. Wallace, et al.. (2019). The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection. The Journal of Immunology. 203(1). 117–126. 27 indexed citations
10.
Rivadeneira, Dayana B., Kristin DePeaux, Yiyang Wang, et al.. (2019). Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance. Immunity. 51(3). 548–560.e4. 110 indexed citations
11.
Najjar, Yana G., Ashley V. Menk, Cindy Sander, et al.. (2019). Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma. JCI Insight. 4(5). 171 indexed citations
12.
Liu, Chang, Maria Chikina, Rahul Deshpande, et al.. (2019). Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ. Immunity. 51(2). 381–397.e6. 266 indexed citations
13.
Majumder, Saikat, Nilesh Amatya, Shankar Revu, et al.. (2019). IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival. Nature Immunology. 20(5). 534–545. 76 indexed citations
14.
Tilstra, Jeremy S., Lyndsay Avery, Ashley V. Menk, et al.. (2018). Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted. Journal of Clinical Investigation. 128(11). 4884–4897. 104 indexed citations
15.
Revu, Shankar, Jing Wu, Matthew Henkel, et al.. (2018). IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation. Cell Reports. 22(10). 2642–2653. 157 indexed citations
16.
Menk, Ashley V., Nicole E. Scharping, Rebecca S. Moreci, et al.. (2018). Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions. Cell Reports. 22(6). 1509–1521. 343 indexed citations breakdown →
17.
Scharping, Nicole E., Ashley V. Menk, Ryan D. Whetstone, Xue Zeng, & Greg M. Delgoffe. (2016). Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia. Cancer Immunology Research. 5(1). 9–16. 399 indexed citations breakdown →
18.
Phong, Binh, Lyndsay Avery, Ashley V. Menk, Greg M. Delgoffe, & Larry Kane. (2016). Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions. The Journal of Immunology. 198(2). 640–644. 37 indexed citations
19.
Scharping, Nicole E., Ashley V. Menk, Rebecca S. Moreci, et al.. (2016). The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction. Immunity. 45(2). 374–388. 562 indexed citations breakdown →
20.
Hawse, William F., Robert P. Sheehan, Nataša Miškov-Živanov, et al.. (2015). Cutting Edge: Differential Regulation of PTEN by TCR, Akt, and FoxO1 Controls CD4+ T Cell Fate Decisions. The Journal of Immunology. 194(10). 4615–4619. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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