David L. Silver

8.8k total citations · 1 hit paper
80 papers, 6.7k citations indexed

About

David L. Silver is a scholar working on Molecular Biology, Surgery and Biochemistry. According to data from OpenAlex, David L. Silver has authored 80 papers receiving a total of 6.7k indexed citations (citations by other indexed papers that have themselves been cited), including 42 papers in Molecular Biology, 28 papers in Surgery and 21 papers in Biochemistry. Recurrent topics in David L. Silver's work include Lipid metabolism and biosynthesis (18 papers), Cholesterol and Lipid Metabolism (16 papers) and Drug Transport and Resistance Mechanisms (16 papers). David L. Silver is often cited by papers focused on Lipid metabolism and biosynthesis (18 papers), Cholesterol and Lipid Metabolism (16 papers) and Drug Transport and Resistance Mechanisms (16 papers). David L. Silver collaborates with scholars based in United States, Singapore and United Kingdom. David L. Silver's co-authors include Alan R. Tall, Nan Wang, Jun Nakae, Domenico Accili, Tadahiro Kitamura, Long N. Nguyen, Markus R. Wenk, Amaury Cazenave‐Gassiot, Philippe Costet and David A. Gross and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

David L. Silver

78 papers receiving 6.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

2014 743 citations Long N. Nguyen, Amaury Cazenave‐Gassiot et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David L. Silver United States	40	3.7k	2.5k	1.3k	1.2k	1.1k	80	6.7k
Ken Ohashi Japan	37	3.2k 0.9×	2.5k 1.0×	958 0.8×	1.1k 1.0×	1.1k 1.0×	85	6.4k
Guosheng Liang United States	35	3.8k 1.0×	3.6k 1.4×	1.1k 0.9×	1.3k 1.1×	1.7k 1.6×	60	8.4k
Russell A. DeBose‐Boyd United States	35	3.8k 1.0×	3.1k 1.3×	660 0.5×	1.1k 1.0×	514 0.5×	62	6.4k
Yoko Iizuka Japan	32	3.1k 0.8×	2.2k 0.9×	630 0.5×	1.2k 1.0×	1.1k 1.0×	65	5.9k
Stephen D. Turley United States	41	3.6k 1.0×	4.6k 1.9×	2.1k 1.7×	612 0.5×	2.2k 2.1×	85	8.1k
Takanari Gotoda Japan	48	3.8k 1.0×	3.1k 1.3×	729 0.6×	1.2k 1.1×	1.3k 1.2×	114	8.4k
Noam Zelcer Netherlands	43	3.3k 0.9×	3.1k 1.3×	3.2k 2.5×	502 0.4×	1.0k 1.0×	95	8.6k
Enrique Sáez United States	38	3.7k 1.0×	1.3k 0.5×	990 0.8×	452 0.4×	1.1k 1.0×	71	6.1k
Ta‐Yuan Chang United States	55	5.3k 1.4×	4.7k 1.9×	861 0.7×	2.0k 1.8×	2.0k 1.8×	160	9.5k
Michael R. Briggs United States	20	4.5k 1.2×	1.8k 0.7×	689 0.5×	648 0.6×	1.2k 1.2×	25	6.4k

Countries citing papers authored by David L. Silver

Since Specialization

Citations

This map shows the geographic impact of David L. Silver's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David L. Silver with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David L. Silver more than expected).

Fields of papers citing papers by David L. Silver

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David L. Silver. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David L. Silver. The network helps show where David L. Silver may publish in the future.

Co-authorship network of co-authors of David L. Silver

This figure shows the co-authorship network connecting the top 25 collaborators of David L. Silver. A scholar is included among the top collaborators of David L. Silver based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David L. Silver. David L. Silver is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ding, Mei, Michaela Chocholoušková, Cheen Fei Chin, et al.. (2025). SPNS1 variants cause multiorgan disease and implicate lysophospholipid transport as critical for mTOR-regulated lipid homeostasis. Journal of Clinical Investigation. 135(17). 1 indexed citations

Chin, Cheen Fei, Dwight L.A. Galam, Liang Gao, et al.. (2023). Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition. Journal of Clinical Investigation. 133(17). 12 indexed citations

Galam, Dwight L.A., Bernice H. Wong, Markus R. Wenk, et al.. (2023). Deficiency in the omega-3 lysolipid transporter Mfsd2a leads to aberrant oligodendrocyte lineage development and hypomyelination. Journal of Clinical Investigation. 133(12). 14 indexed citations

Tan, Bryan C., Cheen Fei Chin, Bernice H. Wong, et al.. (2023). Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport. Proceedings of the National Academy of Sciences. 120(10). 28 indexed citations

Chong, Joyce R., Yuek Ling Chai, Deron R. Herr, et al.. (2023). Decreased DHA‐containing phospholipids in the neocortex of dementia with Lewy bodies are associated with soluble Aβ₄₂, phosphorylated α‐synuclein, and synaptopathology. Brain Pathology. 33(6). e13190–e13190. 4 indexed citations

Chin, Cheen Fei, Liang Gao, Bernice H. Wong, et al.. (2023). Mfsd2a-mediated lysolipid transport is important for renal recovery after acute kidney injury. Journal of Lipid Research. 64(8). 100416–100416. 2 indexed citations

Kuk, Alvin C. Y., Mei Ding, Cheen Fei Chin, et al.. (2022). Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage. Proceedings of the National Academy of Sciences. 119(40). e2210353119–e2210353119. 34 indexed citations

Zheng, Xiaofeng, Xin Yi Yeo, Sneha Muralidharan, et al.. (2022). Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes. Proceedings of the National Academy of Sciences. 119(11). e2113074119–e2113074119. 27 indexed citations

Cater, Rosemary J., Satchal K. Erramilli, James E. Keener, et al.. (2021). Structural basis of omega-3 fatty acid transport across the blood–brain barrier. Nature. 595(7866). 315–319. 85 indexed citations

10.

Nusinovici, Simon, Hengtong Li, Sahil Thakur, et al.. (2021). High-Density Lipoprotein 3 Cholesterol and Primary Open-Angle Glaucoma. Ophthalmology. 129(3). 285–294. 25 indexed citations

11.

Beppu, Lisa, Ashley V. Menk, Callen T. Wallace, et al.. (2019). The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection. The Journal of Immunology. 203(1). 117–126. 27 indexed citations

12.

Miranda, Diego A., William C. Krause, Amaury Cazenave‐Gassiot, et al.. (2018). LRH-1 regulates hepatic lipid homeostasis and maintains arachidonoyl phospholipid pools critical for phospholipid diversity. JCI Insight. 3(5). 40 indexed citations

13.

Wong, Bernice H., Cheen Fei Chin, Dwight L.A. Galam, et al.. (2018). The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain. PLoS Biology. 16(8). e2006443–e2006443. 80 indexed citations

14.

Alakbarzade, Vafa, Abdul Hameed, Debra Q Y Quek, et al.. (2015). A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome. Nature Genetics. 47(7). 814–817. 117 indexed citations

15.

Shimizu, Takuya, Tomoko Sugiura, Tomohiko Wakayama, et al.. (2011). PDZK1 Regulates Breast Cancer Resistance Protein in Small Intestine. Drug Metabolism and Disposition. 39(11). 2148–2154. 36 indexed citations

16.

Takeuchi, Kazuya, Tomoko Sugiura, Kazuki Matsubara, et al.. (2011). Pharmacokinetics and Hepatic Uptake of Eltrombopag, a Novel Platelet-Increasing Agent. Drug Metabolism and Disposition. 39(6). 1088–1096. 21 indexed citations

17.

Nguyen, Long N., Zsuzsanna Hamari, Bert Kadereit, et al.. (2011). Candida parapsilosis fat storage-inducing transmembrane (FIT) protein 2 regulates lipid droplet formation and impacts virulence. Microbes and Infection. 13(7). 663–672. 26 indexed citations

18.

Sugiura, Tomoko, Yukio Kato, Tomohiko Wakayama, et al.. (2008). PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice. Drug Metabolism and Disposition. 36(6). 1181–1188. 44 indexed citations

19.

Nakae, Jun, Tadahiro Kitamura, David L. Silver, & Domenico Accili. (2001). The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. Journal of Clinical Investigation. 108(9). 1359–1367. 465 indexed citations

20.

Wang, Nan, David L. Silver, Christoph Thiele, & Alan R. Tall. (2001). ATP-binding Cassette Transporter A1 (ABCA1) Functions as a Cholesterol Efflux Regulatory Protein. Journal of Biological Chemistry. 276(26). 23742–23747. 405 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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