Veit Hornung

57.4k citations

201 papers · 39.5k indexed · 21 hit papers · h-index 78

Immunology top 0.01%
Molecular Biology top 0.05%
Epidemiology top 0.2%
Infectious Diseases top 0.2%
Surgery top 1%

Co-authors: Eicke Latz Katherine A. Fitzgerald Franz Bauernfeind Gunther Hartmann Karl‐Peter Hopfner Andrea Ablasser Stefan Endres Gábor Horváth
Topics: interferon and immune responses (86 papers)Immune Response and Inflammation (82 papers)Inflammasome and immune disorders (70 papers)
Cited by: Immunology Molecular Biology Biological Psychiatry
Journals: Nature Science Cell
Partner nations: Germany United States Switzerland

In The Last Decade

Veit Hornung

197 papers receiving 38.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

2010 3.1k citations Franz Bauernfeind, Veit Hornung et al. Nature profile →
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

2009 2.4k citations Franz Bauernfeind, Veit Hornung et al. profile →
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

2008 2.4k citations Veit Hornung, Franz Bauernfeind et al. Nature Immunology profile →
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

2009 2.0k citations Veit Hornung, Franz Bauernfeind et al. Nature profile →
The NALP3 inflammasome is involved in the innate immune response to amyloid-β

2008 2.0k citations Veit Hornung, Eicke Latz et al. Nature Immunology profile →
5'-Triphosphate RNA Is the Ligand for RIG-I

2006 1.9k citations Veit Hornung, Sarah Kim-Hellmuth et al. profile →
Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

2002 1.6k citations Veit Hornung, Simon Rothenfußer et al. profile →
Molecular mechanisms and cellular functions of cGAS–STING signalling

2020 1.3k citations Karl‐Peter Hopfner, Veit Hornung profile →
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

2013 1.3k citations Gregor Witte, Karl‐Peter Hopfner et al. Nature profile →
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

2010 1.1k citations Eicke Latz, Veit Hornung et al. Nature Immunology profile →
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7

2005 967 citations Veit Hornung, Carole Bourquin et al. profile →
Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells

2001 735 citations Anne Krug, Simon Rothenfußer et al. profile →
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

2009 689 citations Franz Bauernfeind, Eicke Latz et al. Nature Immunology profile →
Structural mechanism of cytosolic DNA sensing by cGAS

2013 669 citations Carina C. de Oliveira Mann, Gregor Witte et al. Nature profile →
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

2001 628 citations Anne Krug, Simon Rothenfußer et al. profile →
Human Monocytes Engage an Alternative Inflammasome Pathway

2016 591 citations Moritz M. Gaidt, Thomas S. Ebert et al. profile →
Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

2011 532 citations Franz Bauernfeind, Veit Hornung et al. profile →
Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

2013 503 citations Jonathan L. Schmid‐Burgk, Eicke Latz et al. Nature profile →
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3

2017 475 citations Moritz M. Gaidt, Thomas S. Ebert et al. Cell profile →
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders

2017 395 citations Carina C. de Oliveira Mann, David Drexler et al. Nature profile →
Recognition of Endogenous Nucleic Acids by the Innate Immune System

2016 391 citations Veit Hornung et al. profile →

Peers

Countries citing papers authored by Veit Hornung

Since Specialization

Citations

This map shows the geographic impact of Veit Hornung's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Veit Hornung with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Veit Hornung more than expected).

Fields of papers citing papers by Veit Hornung

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Veit Hornung. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Veit Hornung. The network helps show where Veit Hornung may publish in the future.

Co-authorship network of co-authors of Veit Hornung

This figure shows the co-authorship network connecting the top 25 collaborators of Veit Hornung. A scholar is included among the top collaborators of Veit Hornung based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Veit Hornung. Veit Hornung is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets 2025 ·Nature Immunology ·Alexander N.R. Weber,Róisín M. McManus,Veit Hornung,Matthias Geyer,Jasmin Kuemmerle‐Deschner,Eicke Latz	3
2	Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement 2025 ·Cell ·Marleen Bérouti,Mirko Wagner,(unknown),Ignazio Piseddu,(unknown),(unknown),(unknown),Matthias Heiß,(unknown),(unknown),Gregor Witte,Karl‐Peter Hopfner,David Anz,Michael Sattler,Thomas Carell,Veit Hornung	6
3	Sting Activation Improves T-Cell Engaging Immunotherapy of Acute Myeloid Leukemia 2023 ·Blood ·Andreas Linder,Daniel Nixdorf,(unknown),Ignazio Piseddu,(unknown),(unknown),(unknown),Thomas Carell,Roman Kischel,Veit Hornung,Marion Subklewe	1
4	Hemophagocytic lymphohistiocytosis–like hyperinflammation due to a de novo mutation in DPP9 2023 ·Journal of Allergy and Clinical Immunology ·Christine Wolf,(unknown),Jörn‐Sven Kühl,Sarah Koss,Rami Abou Jamra,(unknown),(unknown),Stephan Ehl,Katrin Neumann,Catharina Schuetz,Robert Huber,Veit Hornung,Min Ae Lee‐Kirsch	5
5	Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages 2023 ·The EMBO Journal ·Line Lykke Andersen,Yiqi Huang,Christian Urban,(unknown),Elena Winheim,Che A. Stafford,(unknown),(unknown),Thomas S. Ebert,Thomas Engleitner,Søren R. Paludan,Anne Krug,Roland Rad,Veit Hornung,Andreas Pichlmair	3
6	β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4 2023 ·Cell Reports ·Zhiqi Sun,Filippo M. Cernilogar,(unknown),Assa Yeroslaviz,Zeinab Abdullah,Gunnar Schotta,Veit Hornung	1
7	Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever 2022 ·PLoS Biology ·Matthew Mangan,(unknown),Karoline Krause,(unknown),Anne Pankow,Thomas S. Ebert,Dieter Jahn,Karsten Hiller,Veit Hornung,Marcus Maurer,Florian I. Schmidt,Ralf Gerhard,Eicke Latz	9
8	Novel Poxin Stable cGAMP‐Derivatives Are Remarkable STING Agonists 2022 ·Angewandte Chemie International Edition ·(unknown),Daniel Böhmer,(unknown),(unknown),(unknown),David Drexler,Stefan Bauernfried,Gregor Witte,Mirko Wagner,(unknown),Karl‐Peter Hopfner,Veit Hornung,Lars M. König,Thomas Carell	21
9	Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation 2022 ·Nature ·Che A. Stafford,(unknown),Carina C. de Oliveira Mann,Maria C. Tanzer,Evelyn Fessler,Benedikt Wefers,(unknown),(unknown),Karolina Sulek,Catherine G. Vasilopoulou,(unknown),(unknown),(unknown),Wolfgang Wurst,Monica Yabal,Thomas Fröhlich,Matthias Mann,Nicolas Gisch,Lucas T. Jae,Veit Hornung	50
10	Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses 2021 ·Nature Methods ·Manuel Albanese,(unknown),(unknown),Ernesto Mejías‐Pérez,(unknown),Andreas Linder,Niklas A. Schmacke,Katharina Hofmann,Alexandru A. Hennrich,David N. Levy,Andreas Humpe,Karl‐Klaus Conzelmann,Veit Hornung,O. Fackler,Oliver T. Keppler	18
11	An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation? 2021 ·PLoS Genetics ·Margot Brandt,Sarah Kim-Hellmuth,Marcello Ziosi,Alper Gokden,(unknown),Nora Lam,Yocelyn Recinos,Zharko Daniloski,John Morris,Veit Hornung,Johannes Schumacher,Tuuli Lappalainen	17
12	Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling 2021 ·Nature Communications ·Maria C. Tanzer,Isabell Bludau,Che A. Stafford,Veit Hornung,Matthias Mann	37
13	C-tag TNF: a reporter system to study TNF shedding 2020 ·Journal of Biological Chemistry ·Francesca Pinci,Moritz M. Gaidt,Christophe Jung,(unknown),(unknown),Stefan Bauernfried,Veit Hornung	9
14	The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation 2020 ·European Respiratory Journal ·Christine Huppertz,Benedikt Jäger,Grazyna Wieczorek,Peggy Engelhard,Stephen J. Oliver,(unknown),Amanda Littlewood‐Evans,Tobias Welte,Veit Hornung,Antje Prasse	51
15	IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell 2019 ·Cancer Immunology Research ·Lulu Shao,Weizhou Hou,Nicole E. Scharping,Frank P. Vendetti,Rashmi Srivastava,Chandra Nath Roy,Ashley V. Menk,(unknown),Joë-Marc Chauvin,(unknown),Stephen H. Thorne,Veit Hornung,Hassane M. Zarour,Christopher J. Bakkenist,Greg M. Delgoffe,Saumendra N. Sarkar	52
16	Frequently used bioinformatics tools overestimate the damaging effect of allelic variants 2017 ·Genes and Immunity ·Line Lykke Andersen,Ewa Terczyńska‐Dyla,(unknown),Carsten Scavenius,Jan J. Enghild,Klara Höning,Veit Hornung,Mette Christiansen,Trine H. Mogensen,Rune Hartmann	10
17	The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia 2016 ·Clinical Cancer Research ·Thomas Vercruysse,Jolien De Bie,Jasper E. Neggers,Maarten Jacquemyn,Els Vanstreels,Jonathan L. Schmid‐Burgk,Veit Hornung,Erkan Baloglu,Yosef Landesman,William Senapedis,Sharon Shacham,Antonis Dagklis,Jan Cools,Dirk Daelemans	53
18	Cre-dependent DNA recombination activates a STING-dependent innate immune response 2016 ·Nucleic Acids Research ·Geneviève Pépin,Jonathan Ferrand,Klara Höning,W. Samantha N. Jayasekara,Jason E. Cain,Mark A. Behlke,Daniel J. Gough,Bryan R.G. Williams,Veit Hornung,Michael P. Gantier	35
19	NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR 2016 ·Journal of Virology ·Markus H. Kainulainen,(unknown),Charles E. Samuel,Veit Hornung,Friedemann Weber	49
20	Suppression of Intratumoral CCL22 by Type I Interferon Inhibits Migration of Regulatory T Cells and Blocks Cancer Progression 2015 ·Cancer Research ·David Anz,Moritz Rapp,Stephan Eiber,Viktor H. Koelzer,Raffael Thaler,Sascha Haubner,Maximilian M. L. Knott,Sarah Nagel,Michaela Golić,Gabriela M. Wiedemann,Franz Bauernfeind,Cornelia Wurzenberger,Veit Hornung,Christoph Scholz,Doris Mayr,Simon Rothenfußer,Stefan Endres,Carole Bourquin	63

About Veit Hornung

Veit Hornung is a scholar working on Immunology, Molecular Biology and Virology, having authored 201 papers that have together received 39.5k indexed citations. Recurring topics across this work include interferon and immune responses (86 papers), Immune Response and Inflammation (82 papers) and Inflammasome and immune disorders (70 papers). The work is most often cited by research in Immunology (24.4k citations), Molecular Biology (23.1k citations) and Biological Psychiatry (701 citations). Veit Hornung has collaborated with scholars based in Germany, United States and Switzerland. Frequent co-authors include Eicke Latz, Katherine A. Fitzgerald, Franz Bauernfeind, Gunther Hartmann, Karl‐Peter Hopfner, Andrea Ablasser, Stefan Endres, Gábor Horváth, Jonathan L. Schmid‐Burgk and Simon Rothenfußer. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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