Andrew Singleton

87.2k total citations · 10 hit papers
334 papers, 21.9k citations indexed

About

Andrew Singleton is a scholar working on Neurology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Andrew Singleton has authored 334 papers receiving a total of 21.9k indexed citations (citations by other indexed papers that have themselves been cited), including 185 papers in Neurology, 120 papers in Molecular Biology and 97 papers in Cellular and Molecular Neuroscience. Recurrent topics in Andrew Singleton's work include Parkinson's Disease Mechanisms and Treatments (158 papers), Neurological diseases and metabolism (75 papers) and Nuclear Receptors and Signaling (50 papers). Andrew Singleton is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (158 papers), Neurological diseases and metabolism (75 papers) and Nuclear Receptors and Signaling (50 papers). Andrew Singleton collaborates with scholars based in United States, United Kingdom and Italy. Andrew Singleton's co-authors include John Hardy, Mike A. Nalls, Dena Hernández, Mark Cookson, Cornelis Blauwendraat, Henry Houlden, J. Raphael Gibbs, Katrina Gwinn, Coro Paisán‐Ruíz and Luigi Ferrucci and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Andrew Singleton

329 papers receiving 21.5k citations

Hit Papers

A meta-analysis of genome-wide assoc... 2005 2026 2012 2019 2017 2019 2006 2005 2010 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
    2017 772 citations Mike A. Nalls, Andrew Singleton et al. profile →
  2. The genetic architecture of Parkinson's disease
    2019 685 citations Cornelis Blauwendraat, Mike A. Nalls et al. The Lancet Neurology profile →
  3. Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
    2006 591 citations Patrick A. Lewis, Alice Kaganovich et al. profile →
  4. A common LRRK2 mutation in idiopathic Parkinson's disease
    2005 575 citations Andrew Singleton, Andrew J. Lees et al. profile →
  5. Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain
    2010 536 citations J. Raphael Gibbs, Dena Hernández et al. profile →
  6. Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
    2009 509 citations Andrew Singleton, Andrew J. Lees et al. Brain profile →
  7. Genomewide Association Studies and Human Disease
    2009 484 citations John Hardy, Andrew Singleton profile →
  8. Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations
    2015 388 citations Benjamin Dehay, Mathieu Bourdenx et al. The Lancet Neurology profile →
  9. Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
    2021 229 citations Mike A. Nalls, Andrew Singleton et al. profile →
  10. Virus exposure and neurodegenerative disease risk across national biobanks
    2023 175 citations Kristin Levine, Hampton L. Leonard et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Andrew Singleton United States 73 10.7k 8.2k 5.4k 4.8k 4.3k 334 21.9k
Henry Houlden United Kingdom 70 7.0k 0.7× 8.9k 1.1× 7.0k 1.3× 6.7k 1.4× 5.1k 1.2× 512 20.7k
Christine Klein Germany 70 14.9k 1.4× 6.1k 0.7× 8.3k 1.5× 2.8k 0.6× 3.3k 0.8× 500 22.4k
Matthew J. Farrer United States 77 16.9k 1.6× 6.2k 0.8× 9.1k 1.7× 5.5k 1.1× 5.5k 1.3× 330 22.2k
Peter Heutink Netherlands 60 6.2k 0.6× 6.5k 0.8× 3.6k 0.7× 3.5k 0.7× 2.4k 0.5× 235 16.3k
Gen Sobue Japan 82 11.6k 1.1× 12.4k 1.5× 9.6k 1.8× 4.2k 0.9× 2.9k 0.7× 754 28.1k
Shoji Tsuji Japan 65 6.7k 0.6× 8.8k 1.1× 6.7k 1.2× 3.3k 0.7× 2.3k 0.5× 507 17.1k
Leonard Petrucelli United States 80 12.9k 1.2× 11.2k 1.4× 4.7k 0.9× 7.1k 1.5× 3.2k 0.7× 232 23.2k
Yoshikuni Mizuno Japan 78 14.8k 1.4× 10.1k 1.2× 9.7k 1.8× 4.5k 0.9× 4.8k 1.1× 403 26.7k
Zbigniew K. Wszołek United States 73 12.5k 1.2× 4.6k 0.6× 5.3k 1.0× 5.6k 1.1× 5.0k 1.2× 461 18.9k
Pamela J. Shaw United Kingdom 89 16.6k 1.6× 9.8k 1.2× 5.2k 1.0× 4.7k 1.0× 5.1k 1.2× 486 29.4k

Countries citing papers authored by Andrew Singleton

Since Specialization
Citations

This map shows the geographic impact of Andrew Singleton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew Singleton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew Singleton more than expected).

Fields of papers citing papers by Andrew Singleton

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew Singleton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew Singleton. The network helps show where Andrew Singleton may publish in the future.

Co-authorship network of co-authors of Andrew Singleton

This figure shows the co-authorship network connecting the top 25 collaborators of Andrew Singleton. A scholar is included among the top collaborators of Andrew Singleton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andrew Singleton. Andrew Singleton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Levine, Kristin, Jun Han, Hirotaka Iwaki, et al.. (2025). Sleep disturbances as risk factors for neurodegeneration later in life. ORCA Online Research @Cardiff. 1(1). 2 indexed citations
2.
Grant, Riley, Mary B. Makarious, Lara M. Lange, et al.. (2025). The Global Parkinson’s Disease Genetics (GP2) Genome Browser. medRxiv.
3.
Lake, Julie, Caroline Warly Solsberg, Jonggeol Jeffrey Kim, et al.. (2023). Multi-ancestry meta-analysis and fine-mapping in Alzheimer’s disease. Molecular Psychiatry. 28(7). 3121–3132. 30 indexed citations
4.
Reilly, Luke, Sahba Seddighi, Andrew Singleton, et al.. (2023). Variant biomarker discovery using mass spectrometry-based proteogenomics. SHILAP Revista de lepidopterología. 4. 1191993–1191993. 5 indexed citations
5.
Kaur, Rachneet, Mathew J. Koretsky, Hirotaka Iwaki, et al.. (2023). Application of Aligned-UMAP to longitudinal biomedical studies. Patterns. 4(6). 100741–100741. 11 indexed citations
6.
Langston, Rebekah G., Alexandra Beilina, Xylena Reed, et al.. (2022). Association of a common genetic variant with Parkinson’s disease is mediated by microglia. Science Translational Medicine. 14(655). eabp8869–eabp8869. 50 indexed citations
7.
Xiromerisiou, Georgia, Thomas Bourinaris, Henry Houlden, et al.. (2021). SORL1 mutation in a Greek family with Parkinson's disease and dementia. Annals of Clinical and Translational Neurology. 8(10). 1961–1969. 4 indexed citations
8.
Zhu, William, Xiaoping Huang, Sara Bandrés‐Ciga, et al.. (2021). Heterozygous PRKN mutations are common but do not increase the risk of Parkinson’s disease. Brain. 145(6). 2077–2091. 31 indexed citations
9.
Jacobs, Benjamin M., Jonathan P. Bestwick, Cornelis Blauwendraat, et al.. (2020). Parkinson’s disease determinants, prediction and gene–environment interactions in the UK Biobank. Journal of Neurology Neurosurgery & Psychiatry. 91(10). 1046–1054. 74 indexed citations
10.
Sargent, Lana, Mike A. Nalls, Elaine J. Amella, et al.. (2020). Shared mechanisms for cognitive impairment and physical frailty: A model for complex systems. Alzheimer s & Dementia Translational Research & Clinical Interventions. 6(1). e12027–e12027. 40 indexed citations
11.
Krohn, Lynne, Francis P. Grenn, Mary B. Makarious, et al.. (2020). Comprehensive assessment of PINK1 variants in Parkinson's disease. Neurobiology of Aging. 91. 168.e1–168.e5. 28 indexed citations
12.
Leonard, Hampton L., Cornelis Blauwendraat, Lynne Krohn, et al.. (2019). Genetic variability and potential effects on clinical trial outcomes: perspectives in Parkinson’s disease. Journal of Medical Genetics. 57(5). 331–338. 40 indexed citations
13.
Singleton, Andrew, John Hardy, & Thomas Gasser. (2017). The Birth of the Modern Era of Parkinson's Disease Genetics. UCL Discovery (University College London). 15 indexed citations
14.
Levine, Morgan E., Ake T. Lu, Brian H. Chen, et al.. (2016). Menopause accelerates biological aging. Proceedings of the National Academy of Sciences. 113(33). 9327–9332. 319 indexed citations
15.
Hernández, Dena, Xylena Reed, & Andrew Singleton. (2016). Genetics in Parkinson disease: Mendelian versus non‐Mendelian inheritance. Journal of Neurochemistry. 139(S1). 59–74. 314 indexed citations
16.
Dehay, Benjamin, Mathieu Bourdenx, Philippe Gorry, et al.. (2015). Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations. The Lancet Neurology. 14(8). 855–866. 388 indexed citations breakdown →
17.
Schlebusch, Carina M., Pontus Skoglund, Per Sjödin, et al.. (2012). Genomic Variation in Seven Khoe-San Groups Reveals Adaptation and Complex African History. Science. 338(6105). 374–379. 258 indexed citations
18.
Wang, Chaolong, Zachary A. Szpiech, J. H. Degnan, et al.. (2010). Comparing Spatial Maps of Human Population-Genetic Variation Using Procrustes Analysis. Statistical Applications in Genetics and Molecular Biology. 9(1). Article 13–Article 13. 94 indexed citations
19.
Matarín, Mar, Javier Simón‐Sánchez, Hon‐Chung Fung, et al.. (2008). Structural genomic variation in ischemic stroke. Neurogenetics. 9(2). 101–108. 21 indexed citations
20.
Fung, Hon‐Chung, Chiung‐Mei Chen, John Hardy, et al.. (2005). Analysis of the PINK1 gene in a cohort of patients with sporadic early-onset parkinsonism in Taiwan. Neuroscience Letters. 394(1). 33–36. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Henry Houlden Breakdown of academic impact, for papers by Christine Klein Breakdown of academic impact, for papers by Matthew J. Farrer Breakdown of academic impact, for papers by Peter Heutink Breakdown of academic impact, for papers by Gen Sobue Breakdown of academic impact, for papers by Shoji Tsuji Breakdown of academic impact, for papers by Leonard Petrucelli Breakdown of academic impact, for papers by Yoshikuni Mizuno Breakdown of academic impact, for papers by Zbigniew K. Wszołek Breakdown of academic impact, for papers by Pamela J. Shaw
Rankless by CCL
2026