Ake T. Lu

16.9k total citations · 6 hit papers
55 papers, 5.9k citations indexed

About

Ake T. Lu is a scholar working on Molecular Biology, Genetics and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, Ake T. Lu has authored 55 papers receiving a total of 5.9k indexed citations (citations by other indexed papers that have themselves been cited), including 41 papers in Molecular Biology, 16 papers in Genetics and 14 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in Ake T. Lu's work include Epigenetics and DNA Methylation (39 papers), Birth, Development, and Health (12 papers) and Genetics and Neurodevelopmental Disorders (9 papers). Ake T. Lu is often cited by papers focused on Epigenetics and DNA Methylation (39 papers), Birth, Development, and Health (12 papers) and Genetics and Neurodevelopmental Disorders (9 papers). Ake T. Lu collaborates with scholars based in United States, United Kingdom and Italy. Ake T. Lu's co-authors include Steve Horvath, Luigi Ferrucci, Themistocles L. Assimes, Austin Quach, Alex P. Reiner, Lifang Hou, James G. Wilson, James D. Stewart, Abraham Aviv and Eric A. Whitsel and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Communications and SHILAP Revista de lepidopterología.

In The Last Decade

Ake T. Lu

53 papers receiving 5.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An epigenetic biomarker of aging for lifespan and healthspan

2018 1.9k citations Morgan E. Levine, Ake T. Lu et al. Aging profile →
DNA methylation GrimAge strongly predicts lifespan and healthspan

2019 1.3k citations Ake T. Lu, Austin Quach et al. Aging profile →
GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality

2020 287 citations Ake T. Lu, Steve Horvath et al. profile →
Biological age is increased by stress and restored upon recovery

2023 118 citations Gurpreet S. Baht, Alexander Tyshkovskiy et al. profile →
Causality-enriched epigenetic age uncouples damage and adaptation

2024 72 citations Kejun Ying, Andrei E. Tarkhov et al. Nature Aging profile →
Refining epigenetic prediction of chronological and biological age

2023 65 citations Elena Bernabeu, Daniel L. McCartney et al. Genome Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ake T. Lu United States	28	3.4k	1.3k	1.1k	797	665	55	5.9k
Brian H. Chen United States	20	1.9k 0.6×	710 0.5×	747 0.7×	531 0.7×	368 0.6×	39	3.5k
SriniVas R. Sadda United States	14	2.0k 0.6×	611 0.5×	461 0.4×	435 0.5×	263 0.4×	23	3.2k
Guy Hughes United States	10	2.1k 0.6×	611 0.5×	467 0.4×	451 0.6×	263 0.4×	16	2.9k
Alex P. Reiner United States	36	2.8k 0.8×	1.1k 0.8×	1.2k 1.1×	939 1.2×	508 0.8×	115	6.5k
Brandy Klotzle United States	24	3.8k 1.1×	806 0.6×	557 0.5×	1.0k 1.3×	326 0.5×	35	4.9k
Toby Andrew United Kingdom	33	1.7k 0.5×	697 0.5×	1.5k 1.3×	932 1.2×	136 0.2×	75	5.4k
Sarah E. Harris United Kingdom	45	2.1k 0.6×	714 0.6×	1.3k 1.2×	1.8k 2.3×	491 0.7×	141	6.8k
Morgan E. Levine United States	37	3.5k 1.0×	1.6k 1.2×	2.5k 2.3×	903 1.1×	1.1k 1.7×	82	8.6k
Alison Pattie United Kingdom	35	777 0.2×	730 0.6×	817 0.7×	495 0.6×	496 0.7×	74	5.0k
James G. Wilson United States	21	2.3k 0.7×	940 0.7×	991 0.9×	585 0.7×	473 0.7×	41	4.4k

Countries citing papers authored by Ake T. Lu

Since Specialization

Citations

This map shows the geographic impact of Ake T. Lu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ake T. Lu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ake T. Lu more than expected).

Fields of papers citing papers by Ake T. Lu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ake T. Lu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ake T. Lu. The network helps show where Ake T. Lu may publish in the future.

Co-authorship network of co-authors of Ake T. Lu

This figure shows the co-authorship network connecting the top 25 collaborators of Ake T. Lu. A scholar is included among the top collaborators of Ake T. Lu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ake T. Lu. Ake T. Lu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Li, Caesar Z., Amin Haghani, Qi Yan, et al.. (2024). Epigenetic predictors of species maximum life span and other life-history traits in mammals. Science Advances. 10(23). eadm7273–eadm7273. 21 indexed citations

Nguyen, Steve, Linda K. McEvoy, Mark A. Espeland, et al.. (2024). Associations of Epigenetic Age Estimators With Cognitive Function Trajectories in the Women's Health Initiative Memory Study. Neurology. 103(1). e209534–e209534. 2 indexed citations

Horvath, Steve, Ezequiel Lacunza, Enrique Leo Portiansky, et al.. (2024). Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy. GeroScience. 47(1). 809–823. 6 indexed citations

Ying, Kejun, Andrei E. Tarkhov, Marie C. Sadler, et al.. (2024). Causality-enriched epigenetic age uncouples damage and adaptation. Nature Aging. 4(2). 231–246. 72 indexed citations breakdown →

Zhang, Joshua, Mary E. Sehl, Roger Shih, et al.. (2024). Effects of highly active antiretroviral therapy initiation on epigenomic DNA methylation in persons living with HIV. SHILAP Revista de lepidopterología. 4. 1357889–1357889. 3 indexed citations

Zhang, Bohan, David E. Lee, Alexandre Trapp, et al.. (2023). Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation. Nature Aging. 3(8). 948–964. 56 indexed citations

Zhang, Joshua, Julián A. Martínez-Agosto, Christopher Cunniff, et al.. (2023). Bloom syndrome patients and mice display accelerated epigenetic aging. Aging Cell. 22(10). e13964–e13964. 5 indexed citations

Bernabeu, Elena, Daniel L. McCartney, Danni A. Gadd, et al.. (2023). Refining epigenetic prediction of chronological and biological age. Genome Medicine. 15(1). 12–12. 65 indexed citations breakdown →

Radák, Zsolt, Ferenc Torma, Mátyás Jókai, et al.. (2023). DNAmFitAge: biological age indicator incorporating physical fitness. Aging. 15(10). 3904–3938. 53 indexed citations

10.

Horvath, Steve, Amin Haghani, Joseph A. Zoller, et al.. (2023). Pan-primate studies of age and sex. GeroScience. 45(6). 3187–3209. 8 indexed citations

11.

Arneson, A, Amin Haghani, Michael J. Thompson, et al.. (2022). A mammalian methylation array for profiling methylation levels at conserved sequences. Nature Communications. 13(1). 783–783. 104 indexed citations

12.

Kerepesi, Csaba, Margarita Meer, Julia Ablaeva, et al.. (2022). Epigenetic aging of the demographically non-aging naked mole-rat. Nature Communications. 13(1). 355–355. 28 indexed citations

13.

Ori, Anil P. S., Ake T. Lu, Steve Horvath, & Roel A. Ophoff. (2022). Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies. Genome biology. 23(1). 225–225. 10 indexed citations

14.

Sugrue, Victoria J, Joseph A. Zoller, Pritika Narayan, et al.. (2021). Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci. eLife. 10. 42 indexed citations

15.

Paul, Kimberly C., Ake T. Lu, Steve Horvath, et al.. (2021). DNA methylation-based surrogates of plasma proteins are associated with Parkinson's disease risk. Journal of the Neurological Sciences. 431. 120046–120046. 5 indexed citations

16.

Raffield, Laura M., Ake T. Lu, Mindy D Szeto, et al.. (2020). Coagulation factor VIII: Relationship to cardiovascular disease risk and whole genome sequence and epigenome‐wide analysis in African Americans. Journal of Thrombosis and Haemostasis. 18(6). 1335–1347. 14 indexed citations

17.

Gibson, Jude, Tom C. Russ, Toni‐Kim Clarke, et al.. (2019). A meta-analysis of genome-wide association studies of epigenetic age acceleration. PLoS Genetics. 15(11). e1008104–e1008104. 74 indexed citations

18.

Levine, Morgan E., Ake T. Lu, Brian H. Chen, et al.. (2016). Menopause accelerates biological aging. Proceedings of the National Academy of Sciences. 113(33). 9327–9332. 319 indexed citations

19.

Lu, Ake T., et al.. (2008). Comparing the Glaucoma Diagnostic Accuracy of OCT, GDx, and HRT II Using Best Composite Scores. Investigative Ophthalmology & Visual Science. 49(13). 3641–3641. 1 indexed citations

20.

Tan, Ou, Gisèle Li, Ake T. Lu, Rohit Varma, & David Huang. (2007). Mapping of Macular Substructures with Optical Coherence Tomography for Glaucoma Diagnosis. Ophthalmology. 115(6). 949–956. 285 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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