Gert Vriend

31.2k citations

192 papers · 21.0k indexed · 10 hit papers · h-index 63

Impact in

Molecular Biology top 0.1%
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- Receptor Mechanisms and Signaling
- Enzyme Catalysis and Immobilization
Biotechnology top 0.1%
- Enzyme Production and Characterization

Papers in

Molecular Biology 148
- Protein Structure and Dynamics 71
- Receptor Mechanisms and Signaling 22
- RNA and protein synthesis mechanisms 18
- Biochemical and Structural Characterization 12
Biotechnology 15
- Enzyme Production and Characterization 13

Co-authors: Elmar Krieger Günther Koraimann Maarten L. Hekkelman Rob Hooft Robbie P. Joosten Vincent G. H. Eijsink Sander B. Nabuurs Daan M. F. van Aalten
Journals: Protein Engineering Design and Selection (18 papers)Proteins Structure Function and Bioinformatics (12 papers)Nucleic Acids Research (10 papers)Bioinformatics (10 papers)FEBS Letters (8 papers)
Partner nations: Netherlands Germany United States

In The Last Decade

Gert Vriend

192 papers receiving 20.7k citations

Hit Papers

10 papers align trajectories log scale

New ways to boost molecular dynamics simulations 2015 · 759 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2015 Journal of Computational Chemistry
2014 Nucleic Acids Research
2014 Bioinformatics
2010 BMC Bioinformatics
2010 Nucleic Acids Research
2004 Proteins Structure Function and Bioinformatics
2002 Proteins Structure Function and Bioinformatics
1999 Cell
1996 Journal of Computer-Aided Molecular Design
1990 Journal of Molecular Graphics

Peers

Countries citing papers authored by Gert Vriend

Since Specialization

Citations

This map shows the geographic impact of Gert Vriend's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gert Vriend with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gert Vriend more than expected).

Fields of papers citing papers by Gert Vriend

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gert Vriend. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gert Vriend. The network helps show where Gert Vriend may publish in the future.

Co-authors

The 25 scholars most cited alongside Gert Vriend, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Gert Vriend Line = papers co-authored together Gert Vriend links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Entropy and Variability: A Second Opinion by Deep Learning Biomolecules ·Zhi Gui, Li C. Xue, Peter A.C. ’t Hoen, Gert Vriend	2022	3
2	Ten Simples Rules on How to Organise a Bioinformatics Hackathon EMBnet journal ·Susanne Hollmann, Babette Regierer, Teresa K. Attwood, Andreas Gisel, Jacques van Helden, Grégoire Rossier, Paul Kersey, Eija Roine, Gert Vriend, Erik Bongcam‐Rudloff	2021	1
3	Aggregation of population‐based genetic variation over protein domain homologues and its potential use in genetic diagnostics Human Mutation ·Laurens Wiel, Hanka Venselaar, Joris A. Veltman, Gert Vriend, Christian Gilissen	2017	20
4	GPCRdb: the G protein‐coupled receptor database – an introduction British Journal of Pharmacology ·Christian Munk, Vignir Ísberg, Stefan Mordalski, Kasper Harpsøe, Krzysztof Rataj, Alexander S. Hauser, Peter Kolb, Andrzej J. Bojarski, Gert Vriend, David E. Gloriam	2016	151
5	A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine European Journal of Human Genetics ·Se‐Kyung Oh, Jeong‐In Baek, Chunhua Huang, Hanka Venselaar, Herman G.P. Swarts, Seong‐Hyun Park, Muhammad Hashim Raza, Da Jung Jung, Soo‐Young Choi, Sang‐Heon Lee, Thomas Friedrich, Gert Vriend, Jan J. Koenderink, Un‐Kyung Kim, Kyu-Yup Lee	2014	19
6	GPCRDB: an information system for G protein-coupled receptors Nucleic Acids Research ·Vignir Ísberg, Bas Vroling, Rob van der Kant, Kang Li, Gert Vriend, David E. Gloriam	2013	109
7	The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation Biochemical Pharmacology ·Miriam C. Peeters, Lisanne E. Wisse, Blanca I. Maldonado-Guevara, Bas Vroling, Gert Vriend, Adriaan P. IJzerman	2012	51
8	Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank Bioinformatics ·Robbie P. Joosten, 真人尾形, Serge X. Cohen, Gert Vriend, Anastassis Perrakis	2011	81
9	Integrating GPCR-specific information with full text articles BMC Bioinformatics ·Bas Vroling, D. J. Thorne, Philip McDermott, Teresa K. Attwood, Gert Vriend, Steve Pettifer	2011	8
10	WIWS: a protein structure bioinformatics Web service collection Nucleic Acids Research ·Maarten L. Hekkelman, Danny Javier Álvarez Brito, Steve Pettifer, D. J. Thorne, Teresa K. Attwood, Gert Vriend	2010	134
11	Negative Constraints Underlie the ErbB Specificity of Epidermal Growth Factor-like Ligands Journal of Biological Chemistry ·Thomas J. Vogl, Rita Branco, Sander B. Nabuurs, Hanka Venselaar, Valentina Manoel dos Santos, 黄国定, Gert Vriend, Catelijne Stortelers, E.J.J. van Zoelen	2006	5
12	Homology Modeling Methods of biochemical analysis ·Elmar Krieger, Sander B. Nabuurs, Gert Vriend	2003	135
13	Completion and refinement of 3‐D homology models with restricted molecular dynamics: Application to targets 47, 58, and 111 in the CASP modeling competition and posterior analysis Proteins Structure Function and Bioinformatics ·Raphaël Kuhn, Gert Vriend, H. J. C. Berendsen	2002	38
14	Amyloids protect the silkmoth oocyte and embryo FEBS Letters ·Vassiliki A. Iconomidou, Gert Vriend, Stavros J. Hamodrakas	2000	171
15	Site-directed mutagenesis and immobilization for probing a new model of protein stabilization Data Archiving and Networked Services (DANS) ·Johanna Mansfeld, Gert Vriend, OR Veltman, Bertus van den Burg, G Venema, 隆三崎, Renate Ulbrich‐Hofmann	1997	2
16	Identification of the critical calcium site in the thermolysin-like protease of B-stearothermophilus reveals initial steps in thermal unfolding. Data Archiving and Networked Services (DANS) ·OR Veltman, 隆三崎, Gert Vriend, Gerard Venema, Nurhan Ünüsan	1997	4
17	Structural determinants of the stability of thermolysin-like proteinases Nature Structural & Molecular Biology ·Vincent G. H. Eijsink, Radhika Ambatipudi, Yosuke Kishi, Gert Vriend, Gerard Venema	1995	75
18	Predicting local structural changes that result from point mutations Protein Engineering Design and Selection ·Vincenzo De Filippis, Christian Sander, Gert Vriend	1994	44
19	A common step for signal transduction in G protein-coupled receptors Trends in Pharmacological Sciences ·Luciana Gonçalves de Oliveira, A. C. M. Paiva, Chris Sander, Gert Vriend	1994	126
20	Modeling of transmembrane seven helix bundles Protein Engineering Design and Selection ·Philippe Cronet, Chris Sander, Gert Vriend	1993	84

About Gert Vriend

Gert Vriend is a scholar working on Molecular Biology, Biotechnology, Sensory Systems, Materials Chemistry and Spectroscopy, having authored 192 papers that have together received 21.0k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (71 papers), Enzyme Structure and Function (52 papers), Receptor Mechanisms and Signaling (22 papers), RNA and protein synthesis mechanisms (18 papers), Enzyme Production and Characterization (13 papers), Bacteriophages and microbial interactions (12 papers), Computational Drug Discovery Methods (12 papers) and Biochemical and Structural Characterization (12 papers). The work is most often cited by research in Molecular Biology (15.3k citations), Biotechnology (1.4k citations), Computational Theory and Mathematics (1.9k citations), Materials Chemistry (3.7k citations) and Cellular and Molecular Neuroscience (1.3k citations). Gert Vriend has collaborated with scholars based in Netherlands, Germany and United States. Frequent co-authors include Elmar Krieger, Günther Koraimann, Maarten L. Hekkelman, Rob Hooft, Robbie P. Joosten, Vincent G. H. Eijsink, Sander B. Nabuurs, Daan M. F. van Aalten, Hanka Venselaar and Remko Kuipers. Their work appears in journals such as Protein Engineering Design and Selection, Proteins Structure Function and Bioinformatics, Nucleic Acids Research, Bioinformatics and FEBS Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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