Xavier Lucas

3.3k total citations · 1 hit paper
45 papers, 2.4k citations indexed

About

Xavier Lucas is a scholar working on Molecular Biology, Computational Theory and Mathematics and Hematology. According to data from OpenAlex, Xavier Lucas has authored 45 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 31 papers in Molecular Biology, 9 papers in Computational Theory and Mathematics and 7 papers in Hematology. Recurrent topics in Xavier Lucas's work include Protein Degradation and Inhibitors (17 papers), Ubiquitin and proteasome pathways (12 papers) and Computational Drug Discovery Methods (8 papers). Xavier Lucas is often cited by papers focused on Protein Degradation and Inhibitors (17 papers), Ubiquitin and proteasome pathways (12 papers) and Computational Drug Discovery Methods (8 papers). Xavier Lucas collaborates with scholars based in Germany, United Kingdom and Switzerland. Xavier Lucas's co-authors include Alessio Ciulli, Andrea Testa, Morgan S. Gadd, Kwok-Ho Chan, Douglas J. Lamont, Wenzhang Chen, Michael Zengerle, David Quiñonero, Antonio Frontera and Stefan Günther and has published in prestigious journals such as Journal of the American Chemical Society, Nucleic Acids Research and Angewandte Chemie International Edition.

In The Last Decade

Xavier Lucas

44 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural basis of PROTAC cooperative recognition for selective protein degradation

2017 826 citations Morgan S. Gadd, Andrea Testa et al. Nature Chemical Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Xavier Lucas Germany	22	1.9k	590	437	239	222	45	2.4k
Richard Alexander United States	27	1.2k 0.7×	239 0.4×	423 1.0×	260 1.1×	210 0.9×	63	2.6k
A.H. Robbins United States	22	1.3k 0.7×	300 0.5×	279 0.6×	363 1.5×	75 0.3×	42	2.4k
M. Stihle Switzerland	23	1.7k 0.9×	315 0.5×	67 0.2×	324 1.4×	242 1.1×	29	2.8k
David Hangauer United States	27	1.3k 0.7×	353 0.6×	69 0.2×	207 0.9×	350 1.6×	64	2.0k
Neera Borkakoti United Kingdom	25	2.1k 1.1×	425 0.7×	104 0.2×	782 3.3×	363 1.6×	54	2.8k
Carlos H. Faerman United States	16	778 0.4×	133 0.2×	256 0.6×	296 1.2×	319 1.4×	28	1.9k
Regine S. Bohacek United States	23	1.6k 0.9×	384 0.7×	263 0.6×	330 1.4×	975 4.4×	49	2.6k
Daniel F. Ortwine United States	29	1.3k 0.7×	516 0.9×	89 0.2×	111 0.5×	293 1.3×	64	2.6k
António J. M. Ribeiro Portugal	20	933 0.5×	139 0.2×	77 0.2×	273 1.1×	202 0.9×	41	1.5k
Thomas S. Rush United States	24	1.3k 0.7×	247 0.4×	52 0.1×	536 2.2×	701 3.2×	42	2.4k

Countries citing papers authored by Xavier Lucas

Since Specialization

Citations

This map shows the geographic impact of Xavier Lucas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xavier Lucas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xavier Lucas more than expected).

Fields of papers citing papers by Xavier Lucas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xavier Lucas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xavier Lucas. The network helps show where Xavier Lucas may publish in the future.

Co-authorship network of co-authors of Xavier Lucas

This figure shows the co-authorship network connecting the top 25 collaborators of Xavier Lucas. A scholar is included among the top collaborators of Xavier Lucas based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xavier Lucas. Xavier Lucas is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kasaragod, Vikram Babu, Tomas Malinauskas, Judith A. Lengyel, et al.. (2023). The molecular basis of drug selectivity for α5 subunit-containing GABAA receptors. Nature Structural & Molecular Biology. 30(12). 1936–1946. 6 indexed citations

Lucas, Xavier, et al.. (2023). Peptide conformational sampling using the Quantum Approximate Optimization Algorithm. npj Quantum Information. 9(1). 16 indexed citations

D’Amore, Lorenzo, David F. Hahn, David Dotson, et al.. (2022). Collaborative Assessment of Molecular Geometries and Energies from the Open Force Field. Journal of Chemical Information and Modeling. 62(23). 6094–6104. 13 indexed citations

Smith, Daniel G. A., Simon Boothroyd, Hyesu Jang, et al.. (2021). Development and Benchmarking of Open Force Field v1.0.0—the Parsley Small-Molecule Force Field. Journal of Chemical Theory and Computation. 17(10). 6262–6280. 113 indexed citations

Lucas, Xavier, Daniel Wohlwend, Oliver Einsle, et al.. (2020). 4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines. Journal of Medicinal Chemistry. 63(24). 15603–15620. 15 indexed citations

Bray, Simon, Xavier Lucas, Anup Kumar, & Björn Grüning. (2020). The ChemicalToolbox: reproducible, user-friendly cheminformatics analysis on the Galaxy platform. Journal of Cheminformatics. 12(1). 40–40. 31 indexed citations

Lucas, Xavier, et al.. (2019). Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure‐Selectivity Relationship of a Ketoreductase. ChemBioChem. 20(9). 1150–1154. 7 indexed citations

Testa, Andrea, Scott J. Hughes, Xavier Lucas, Jane E. Wright, & Alessio Ciulli. (2019). Structure‐Based Design of a Macrocyclic PROTAC. Angewandte Chemie. 132(4). 1744–1751. 19 indexed citations

Testa, Andrea, Scott J. Hughes, Xavier Lucas, Jane E. Wright, & Alessio Ciulli. (2019). Structure‐Based Design of a Macrocyclic PROTAC. Angewandte Chemie International Edition. 59(4). 1727–1734. 172 indexed citations

10.

Gadd, Morgan S., Andrea Testa, Xavier Lucas, et al.. (2017). Structural basis of PROTAC cooperative recognition for selective protein degradation. Nature Chemical Biology. 13(5). 514–521. 826 indexed citations breakdown →

11.

Lucas, Xavier & Alessio Ciulli. (2017). Recognition of substrate degrons by E3 ubiquitin ligases and modulation by small-molecule mimicry strategies. Current Opinion in Structural Biology. 44. 101–110. 72 indexed citations

12.

Lucas, Xavier, Dmytro Ostrovskyi, Bernhard Breit, et al.. (2016). Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes. Data in Brief. 7. 1370–1374. 1 indexed citations

13.

Lucas, Xavier, Anika Erxleben, Astrid C. Erber, et al.. (2015). StreptomeDB 2.0—an extended resource of natural products produced by streptomycetes. Nucleic Acids Research. 44(D1). D509–D514. 64 indexed citations

14.

Lucas, Xavier, Antonio Bauzá, Antonio Frontera, & David Quiñonero. (2015). A thorough anion–π interaction study in biomolecules: on the importance of cooperativity effects. Chemical Science. 7(2). 1038–1050. 188 indexed citations

15.

Lucas, Xavier, et al.. (2015). Target Fishing by Cross‐Docking to Explain Polypharmacological Effects. ChemMedChem. 10(7). 1209–1217. 18 indexed citations

16.

Lucas, Xavier, Daniel Wohlwend, S. Gerhardt, et al.. (2013). 4‐Acyl Pyrroles: Mimicking Acetylated Lysines in Histone Code Reading. Angewandte Chemie International Edition. 52(52). 14055–14059. 92 indexed citations

17.

Lucas, Xavier, et al.. (2013). Discovery of the Inhibitory Effect of a Phosphatidylinositol Derivative on P-Glycoprotein by Virtual Screening Followed by In Vitro Cellular Studies. PLoS ONE. 8(4). e60679–e60679. 7 indexed citations

18.

Lucas, Xavier, David Quiñonero, Antonio Frontera, & Pere M. Deyà. (2010). The Role of the Ethynyl Substituent on the π–π Stacking Affinity of Benzene: A Theoretical Study. ChemPhysChem. 12(2). 283–288. 4 indexed citations

19.

Estarellas, Carolina, Xavier Lucas, Antonio Frontera, David Quiñonero, & Pere M. Deyà. (2010). Erroneous behaviour of the widely used MP2(full)/aug-cc-pVXZ (X = D,T) level of theory for evaluating the BSSE in ion–π complexes. Chemical Physics Letters. 489(4-6). 254–258. 17 indexed citations

20.

Lucas, Xavier, David Quiñonero, Antonio Frontera, & Pere M. Deyà. (2009). Counterintuitive Substituent Effect of the Ethynyl Group in Ion−π Interactions. The Journal of Physical Chemistry A. 113(38). 10367–10375. 43 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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