Alejandra Álvarez

6.5k total citations · 1 hit paper
90 papers, 5.3k citations indexed

About

Alejandra Álvarez is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Alejandra Álvarez has authored 90 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 55 papers in Physiology, 38 papers in Molecular Biology and 18 papers in Pharmacology. Recurrent topics in Alejandra Álvarez's work include Alzheimer's disease research and treatments (37 papers), Lysosomal Storage Disorders Research (18 papers) and Cholinesterase and Neurodegenerative Diseases (18 papers). Alejandra Álvarez is often cited by papers focused on Alzheimer's disease research and treatments (37 papers), Lysosomal Storage Disorders Research (18 papers) and Cholinesterase and Neurodegenerative Diseases (18 papers). Alejandra Álvarez collaborates with scholars based in Chile, United States and Spain. Alejandra Álvarez's co-authors include Nibaldo C. Inestrosa, Jorge Garrido, Nibaldo C. Inestrosa, Cristián A. Pérez, Silvana Zanlungo, Ricardo D. Moreno, Claudio Soto, Claudia Linker, Juan A. Godoy and Miguel Bronfman and has published in prestigious journals such as Journal of Biological Chemistry, Neuron and Journal of Neuroscience.

In The Last Decade

Alejandra Álvarez

89 papers receiving 5.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Acetylcholinesterase Accelerates Assembly of Amyloid-β-Peptides into Alzheimer's Fibrils: Possible Role of the Peripheral Site of the Enzyme

1996 965 citations Nibaldo C. Inestrosa, Alejandra Álvarez et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alejandra Álvarez Chile	36	2.3k	2.2k	2.1k	1.1k	922	90	5.3k
Sascha Weggen Germany	40	3.8k 1.6×	2.2k 1.0×	1.5k 0.7×	1.1k 0.9×	870 0.9×	93	6.2k
Jason L. Eriksen United States	31	3.2k 1.3×	1.6k 0.7×	1.4k 0.7×	766 0.7×	1.0k 1.1×	62	5.1k
Mark S. Shearman United States	42	3.2k 1.4×	3.4k 1.5×	1.2k 0.6×	795 0.7×	1.2k 1.3×	96	6.0k
Claus U. Pietrzik Germany	42	4.0k 1.7×	2.6k 1.2×	1.1k 0.5×	642 0.6×	991 1.1×	111	6.6k
Geneviève Evin Australia	36	2.8k 1.2×	2.4k 1.1×	953 0.4×	527 0.5×	720 0.8×	83	4.7k
Jan Näslund Sweden	30	5.4k 2.3×	3.4k 1.5×	1.4k 0.6×	1.0k 0.9×	1.0k 1.1×	51	7.0k
Pascale N. Lacor United States	29	4.6k 2.0×	2.2k 1.0×	1.3k 0.6×	704 0.6×	2.0k 2.2×	34	6.1k
Christian Czech Switzerland	38	4.1k 1.7×	2.8k 1.3×	1.1k 0.5×	533 0.5×	1.5k 1.6×	115	6.2k
Dennis J. Selkoe United States	15	4.8k 2.1×	3.2k 1.4×	1.3k 0.6×	898 0.8×	1.2k 1.3×	17	6.4k
Pritam Das United States	41	4.7k 2.0×	2.4k 1.1×	1.3k 0.6×	944 0.8×	1.1k 1.1×	80	7.5k

Countries citing papers authored by Alejandra Álvarez

Since Specialization

Citations

This map shows the geographic impact of Alejandra Álvarez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alejandra Álvarez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alejandra Álvarez more than expected).

Fields of papers citing papers by Alejandra Álvarez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alejandra Álvarez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alejandra Álvarez. The network helps show where Alejandra Álvarez may publish in the future.

Co-authorship network of co-authors of Alejandra Álvarez

This figure shows the co-authorship network connecting the top 25 collaborators of Alejandra Álvarez. A scholar is included among the top collaborators of Alejandra Álvarez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alejandra Álvarez. Alejandra Álvarez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Morales-Zavala, Francisco, Karen Bolaños, Ernest Giralt, et al.. (2023). Differential Detection of Amyloid Aggregates in Old Animals Using Gold Nanorods by Computerized Tomography: A Pharmacokinetic and Bioaccumulation Study. International Journal of Nanomedicine. Volume 18. 8169–8185. 4 indexed citations

Álvarez, Alejandra, et al.. (2022). c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases. Neural Regeneration Research. 18(2). 237–237. 18 indexed citations

Morales-Zavala, Francisco, David Chamorro, Ana Riveros, et al.. (2021). In vivo micro computed tomography detection and decrease in amyloid load by using multifunctionalized gold nanorods: a neurotheranostic platform for Alzheimer's disease. Biomaterials Science. 9(11). 4178–4190. 16 indexed citations

Balboa, Elisa, Tamara Marín, Juan Esteban Oyarzún, et al.. (2021). Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage. Cells. 10(8). 2159–2159. 9 indexed citations

Yanez, Maria, Tamara Marín, Andrés D. Klein, et al.. (2021). c-Abl activates RIPK3 signaling in Gaucher disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1867(5). 166089–166089. 17 indexed citations

Bhuyan, H., M. Favre, U. G. Volkmann, et al.. (2020). Study of nitrogen implantation in Ti surface using plasma immersion ion implantation & deposition technique as biocompatible substrate for artificial membranes. Materials Science and Engineering C. 113. 111002–111002. 28 indexed citations

Casanova, Nathalie, Alejandra Álvarez, D.E. Díaz-Droguett, et al.. (2018). Study of Phospholipid Bilayers Supported on Chitosan-Titanium Nitride Coatings Produced by Plasma Immersion Ion Implantation (PIII). Biophysical Journal. 114(3). 105a–105a.

Vargas, Lina Moitoso de, Waldo Cerpa, Francisco J. Muñoz, Silvana Zanlungo, & Alejandra Álvarez. (2018). Amyloid-β oligomers synaptotoxicity: The emerging role of EphA4/c-Abl signaling in Alzheimer's disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864(4). 1148–1159. 47 indexed citations

Morales-Zavala, Francisco, Lisbell D. Estrada, Fanny Guzmán, et al.. (2018). Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimer’s disease. Journal of Nanobiotechnology. 16(1). 60–60. 31 indexed citations

10.

Balboa, Elisa, Juan Francisco Castro, Gonzalo I. Cancino, et al.. (2017). MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content. Redox Biology. 12. 274–284. 66 indexed citations

11.

Yanez, Maria, Olivia Belbin, Lisbell D. Estrada, et al.. (2016). c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1862(11). 2158–2167. 19 indexed citations

12.

ILL‐Raga, Gerard, Marta Tajes, Arnau Busquets-García, et al.. (2015). Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2α Kinase HRI Induces Synaptogenesis. Antioxidants and Redox Signaling. 22(15). 1295–1307. 27 indexed citations

13.

Rojas, Fabiola, David González, Nicole Cortés, et al.. (2015). Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Frontiers in Cellular Neuroscience. 9. 203–203. 79 indexed citations

14.

Contreras, Pablo S., Maria Yanez, Andrés E. Dulcey, et al.. (2015). Neuronal gene repression in Niemann–Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1859(2). 269–279. 19 indexed citations

15.

Estrada, Lisbell D., Silvana Zanlungo, & Alejandra Álvarez. (2011). C-Abl Tyrosine Kinase Signaling: A New Player in AD Tau Pathology. Current Alzheimer Research. 8(6). 643–651. 17 indexed citations

16.

Klein, Andrés D., Matías Mosqueira, Gabriela Martínez, et al.. (2010). Lack of Activation of the Unfolded Protein Response in Mouse and Cellular Models of Niemann-Pick Type C Disease. Neurodegenerative Diseases. 8(3). 124–128. 11 indexed citations

17.

Arce, Karen Perez de, Lorena Varela‐Nallar, Paulina Bull, et al.. (2010). Synaptic Clustering of PSD-95 Is Regulated by c-Abl through Tyrosine Phosphorylation. Journal of Neuroscience. 30(10). 3728–3738. 46 indexed citations

18.

Muñoz, Juan Pablo, Alejandra Álvarez, & Ricardo B. Maccioni. (2000). Increase in the expression of the neuronal cyclin-dependent protein kinase cdk-5 during differentiation of N2A neuroblastoma cells. Neuroreport. 11(12). 2733–2738. 18 indexed citations

19.

Álvarez, Alejandra, et al.. (1997). Acetylcholinesterase promotes the aggregation of amyloid-β-peptide fragments by forming a complex with the growing fibrils 1 1Edited by A. R. Fersht. Journal of Molecular Biology. 272(3). 348–361. 264 indexed citations

20.

Reyes, Ariel E., Daniel R. Pérez, Alejandra Álvarez, et al.. (1997). A Monoclonal Antibody against Acetylcholinesterase Inhibits the Formation of Amyloid Fibrils Induced by the Enzyme. Biochemical and Biophysical Research Communications. 232(3). 652–655. 94 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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