William E. Paul

53.0k total citations · 20 hit papers
344 papers, 42.5k citations indexed

About

William E. Paul is a scholar working on Immunology, Molecular Biology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, William E. Paul has authored 344 papers receiving a total of 42.5k indexed citations (citations by other indexed papers that have themselves been cited), including 264 papers in Immunology, 59 papers in Molecular Biology and 55 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in William E. Paul's work include Immune Cell Function and Interaction (161 papers), T-cell and B-cell Immunology (154 papers) and Immunotherapy and Immune Responses (67 papers). William E. Paul is often cited by papers focused on Immune Cell Function and Interaction (161 papers), T-cell and B-cell Immunology (154 papers) and Immunotherapy and Immune Responses (67 papers). William E. Paul collaborates with scholars based in United States, Israel and Germany. William E. Paul's co-authors include Jinfang Zhu, Hidehiro Yamane, Clifford M. Snapper, Jane Hu‐Li, Robert A. Seder, John J. O’Shea, Baruj Benacerraf, John D. Stobo, Liying Guo and J Ohara and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

William E. Paul

341 papers receiving 40.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Differentiation of Effector CD4 T Cell Populations

2010 2.6k citations Jinfang Zhu, William E. Paul et al. profile →
Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 1.7k citations William E. Paul et al. Science profile →
Lymphocyte responses and cytokines

1994 1.5k citations William E. Paul, Robert A. Seder profile →
THE IL-4 RECEPTOR: Signaling Mechanisms and Biologic Functions

1999 1.3k citations William E. Paul et al. profile →
CD4 T cells: fates, functions, and faults

2008 1.3k citations Jinfang Zhu, William E. Paul Blood profile →
Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1989 1.0k citations Marshall Plaut, William E. Paul et al. profile →
Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4 ⁺ T Cells

2010 984 citations John J. O’Shea, William E. Paul Science profile →
Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

2009 903 citations Jinfang Zhu, Jane Hu‐Li et al. profile →
Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain

1995 853 citations Jane Hu‐Li, William E. Paul et al. profile →
Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

2008 848 citations Joshua D. Milner, Arian Laurence et al. profile →
How are TH2-type immune responses initiated and amplified?

2010 717 citations William E. Paul, Jinfang Zhu profile →
Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 676 citations William E. Paul et al. profile →
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells

2001 618 citations Dragana Janković, Alan Sher et al. Proceedings of the National Academy of Sciences profile →
NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

2000 559 citations Nancy Noben-Trauth, L. Cynthia Watson et al. profile →
Colocalization of X-Linked Agammaglobulinemia and X-Linked Immunodeficiency Genes

1993 543 citations William E. Paul et al. Science profile →
Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-4 Receptor

1993 522 citations William E. Paul, Warren J. Leonard et al. Science profile →
IL-25-responsive, lineage-negative KLRG1hi cells are multipotential ‘inflammatory’ type 2 innate lymphoid cells

2014 505 citations Yuefeng Huang, Liying Guo et al. profile →
S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense

2018 412 citations Yuefeng Huang, Kairui Mao et al. Science profile →
CARRIER FUNCTION IN ANTI-HAPTEN IMMUNE RESPONSES

1970 226 citations William E. Paul et al. The Journal of Experimental Medicine profile →
Functional Specificity of Thymus-Dependent Lymphocytes

1977 199 citations William E. Paul et al. Science profile →

Peers

Countries citing papers authored by William E. Paul

Since Specialization

Citations

This map shows the geographic impact of William E. Paul's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William E. Paul with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William E. Paul more than expected).

Fields of papers citing papers by William E. Paul

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William E. Paul. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William E. Paul. The network helps show where William E. Paul may publish in the future.

Co-authorship network of co-authors of William E. Paul

This figure shows the co-authorship network connecting the top 25 collaborators of William E. Paul. A scholar is included among the top collaborators of William E. Paul based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William E. Paul. William E. Paul is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense breakdown → 2018 ·Science ·Yuefeng Huang, Kairui Mao, Xi Chen, Ming‐an Sun, Takeshi Kawabe, Weizhe Li, (unknown), Jinfang Zhu, Joseph F. Urban, William E. Paul, Ronald N. Germain	412
2	Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3 2013 ·Journal of Allergy and Clinical Immunology ·Ilkka Junttila, L. Cynthia Watson, Laura Kummola, Xi Chen, Jane Hu‐Li, Liying Guo, Ryoji Yagi, William E. Paul	45
3	Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number 2011 ·Proceedings of the National Academy of Sciences ·Juan Quiel, Stéphane Caucheteux, Arian Laurence, Nevil J. Singh, Gennady Bocharov, Shlomo Z. Ben‐Sasson, Zvi Grossman, William E. Paul	29
4	Evidence that Growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells 2010 ·Blood ·Cyrus Khandanpour, Ehssan Sharif‐Askari, Lothar Vaßen, Marie‐Claude Gaudreau, Jinfang Zhu, William E. Paul, Taro Okayama, Christian Kosan, Tarik Möröy	61
5	Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4 ⁺ T Cells breakdown → 2010 ·Science ·John J. O’Shea, William E. Paul	984
6	Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation 2010 ·Blood ·Joshua D. Milner, Tatyana Orekov, Jerrold M. Ward, Lily Cheng, Fernando Torres‐Velez, Ilkka Junttila, Guangping Sun, Mark Buller, Suzanne C. Morris, Fred D. Finkelman, William E. Paul	90
7	Formation of IL-7Rαhigh and IL-7Rαlow CD8 T Cells during Infection Is Regulated by the Opposing Functions of GABPα and Gfi-1 2008 ·The Journal of Immunology ·Anmol Chandele, Nikhil S. Joshi, Jinfang Zhu, William E. Paul, Warren J. Leonard, Susan M. Kaech	68
8	Elevating Calcium in Th2 Cells Activates Multiple Pathways to Induce IL-4 Transcription and mRNA Stabilization 2008 ·The Journal of Immunology ·Liying Guo, Joseph F. Urban, Jinfang Zhu, William E. Paul	32
9	Jak3 negatively regulates dendritic-cell cytokine production and survival 2005 ·Blood ·Kunihiro Yamaoka, Booki Min, (unknown), William E. Paul, John J. O’Shea	54
10	Mechanisms of lymphocyte activation and immune regulation X : innate immunity 2005 ·Springer eBooks ·(unknown), (unknown), William E. Paul, Ralph M. Steinman	4
11	IL-6 Increases Primed Cell Expansion and Survival 2005 ·The Journal of Immunology ·(unknown), William E. Paul, Shlomo Z. Ben‐Sasson	107
12	Basophils Produce IL-4 and Accumulate in Tissues after Infection with a Th2-inducing Parasite 2004 ·The Journal of Experimental Medicine ·Booki Min, Melanie Prout, Jane Hu‐Li, Jinfang Zhu, Dragana Janković, Ellen S. Morgan, Joseph F. Urban, Ann M. Dvořàk, Fred D. Finkelman, Graham Le Gros, William E. Paul	353
13	Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation 2003 ·Proceedings of the National Academy of Sciences ·Max Löhning, Anne Richter, (unknown), Jane Hu‐Li, Mario Assenmacher, William E. Paul, Andreas Radbruch	29
14	The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility to Leishmania major 2003 ·The Journal of Immunology ·Nancy Noben-Trauth, (unknown), Hisashi Nagase, William E. Paul, David L. Sacks	111
15	Cell Division Is Not a “Clock” Measuring Acquisition of Competence to Produce IFN-γ or IL-4 2001 ·The Journal of Immunology ·Shlomo Z. Ben‐Sasson, (unknown), Jane Hu‐Li, William E. Paul	65
16	Single Cell Analysis Reveals That IL-4 Receptor/Stat6 Signaling Is Not Required for the In Vivo or In Vitro Development of CD4+ Lymphocytes with a Th2 Cytokine Profile 2000 ·The Journal of Immunology ·Dragana Janković, Marika C. Kullberg, Nancy Noben-Trauth, Patricia Caspar, William E. Paul, Alan Sher	202
17	Protein Tyrosine Phosphatase Activity Is Required for IL-4 Induction of IL-4 Receptor α-Chain 2000 ·The Journal of Immunology ·Hua Huang, William E. Paul	26
18	Conventional, Naive CD4+ T Cells Provide an Initial Source of IL-4 During Th2 Differentiation 2000 ·The Journal of Immunology ·Nancy Noben-Trauth, Jane Hu‐Li, William E. Paul	97
19	Lymphokine and Cytokine Production by FcεRI+ Cells 1993 ·Advances in immunology ·William E. Paul, Robert A. Seder, Marshall Plaut	103
20	Immune response to levan. III. The capacity to produce anti-inulin antibodies and cross-reactive idiotypes appears late in ontogeny. 1979 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Constantin A. Bona, James J. Mond, Kathryn E. Stein, Shirley B. House, Rose Lieberman, William E. Paul	50

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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