Kazuyuki Tobe

40.0k citations

307 papers · 18.5k indexed · 6 hit papers · h-index 70

Molecular Biology top 0.2%
Physiology top 0.2%
Epidemiology top 0.5%
Surgery top 0.5%
Endocrinology, Diabetes and Metabolism top 0.2%

Co-authors: Takashi Kadowaki Toshimasa Yamauchi Ryozo Nagai Yasuo Terauchi Yoshio Yazaki Kohjiro Ueki Naoto Kubota Hiroyuki Tamemoto
Topics: Metabolism, Diabetes, and Cancer (66 papers)Adipose Tissue and Metabolism (51 papers)Adipokines, Inflammation, and Metabolic Diseases (43 papers)
Cited by: Endocrinology, Diabetes and Metabolism Physiology Geriatrics and Gerontology
Journals: Nature Science Journal of Biological Chemistry
Partner nations: Japan United States United Kingdom

In The Last Decade

Kazuyuki Tobe

294 papers receiving 18.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1

1994 859 citations Hiroyuki Tamemoto, Takashi Kadowaki et al. profile →
Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene

2001 777 citations Ryo Suzuki, Kazuyuki Tobe et al. profile →
Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

2009 586 citations Shiho Fujisaka, Isao Usui et al. profile →
The Mechanisms by Which Both Heterozygous Peroxisome Proliferator-activated Receptor γ (PPARγ) Deficiency and PPARγ Agonist Improve Insulin Resistance

2001 550 citations Toshimasa Yamauchi, Hironori Waki et al. Journal of Biological Chemistry profile →
Japanese Clinical Practice Guideline for Diabetes 2019

2020 380 citations Mitsuhiko Noda, Hideki Origasa et al. profile →
Semaglutide once a week in adults with overweight or obesity, with or without type 2 diabetes in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a trial

2022 205 citations Takashi Kadowaki, Kazuyuki Tobe et al. profile →

Peers

Countries citing papers authored by Kazuyuki Tobe

Since Specialization

Citations

This map shows the geographic impact of Kazuyuki Tobe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kazuyuki Tobe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kazuyuki Tobe more than expected).

Fields of papers citing papers by Kazuyuki Tobe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kazuyuki Tobe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kazuyuki Tobe. The network helps show where Kazuyuki Tobe may publish in the future.

Co-authorship network of co-authors of Kazuyuki Tobe

This figure shows the co-authorship network connecting the top 25 collaborators of Kazuyuki Tobe. A scholar is included among the top collaborators of Kazuyuki Tobe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kazuyuki Tobe. Kazuyuki Tobe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Peripheral CD4 memory T cells predict the efficacy of immune checkpoint inhibitor therapy in patients with non-small cell lung cancer 2023 ·Scientific Reports ·Minehiko Inomata,(unknown),Naoki Takata,(unknown),(unknown),(unknown),(unknown),(unknown),Seisuke Okazawa,Kenta Kambara,Shingo Imanishi,Toshiro Miwa,Ryuji Hayashi,Shoko Matsui,Kazuyuki Tobe	10
2	A Case Report of Anti-TIF1-γAntibody-Positive Dermatomyositis Concomitant with Small Cell Neuroendocrine Carcinoma of the Urinary Bladder 2023 ·SHILAP Revista de lepidopterología ·Hiroyuki Hounoki,(unknown),Miho Yamazaki,(unknown),Satoshi Yamaguchi,(unknown),Kazuyuki Tobe,Akira Noguchi,Kenichi Hirabayashi	0
3	Increased Number of Mucosal-Associated Invariant T Cells Is Associated with the Inhibition of Nonalcoholic Fatty Liver Disease in High Fat Diet–Fed Mice 2022 ·International Journal of Molecular Sciences ·(unknown),Isao Usui,Teruo Jojima,Shiho Fujisaka,(unknown),(unknown),(unknown),Shintaro Sakurai,Toshie Iijima,Takuya Tomaru,Kazuyuki Tobe,Yoshimasa Aso	2
4	High prevalence of fragmented QRS on electrocardiography in Japanese patients with diabetes irrespective of metabolic syndrome 2021 ·Journal of Diabetes Investigation ·Kunimasa Yagi,(unknown),Takashi Yamagami,Daisuke Chujo,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Shiho Fujisaka,Hideki Origasa,Kazuyuki Tobe	5
5	TCR function analysis using a novel system reveals the multiple unconventional tumor‐reactive T cells in human breast cancer‐infiltrating lymphocytes 2021 ·European Journal of Immunology ·Satoshi Yamaguchi,Hiroshi Hamana,(unknown),(unknown),Takuya Nagata,(unknown),Eiji Kobayashi,Tatsuhiko Ozawa,Tsutomu Fujii,Atsushi Muraguchi,Kazuyuki Tobe,Hiroyuki Kishi	6
6	Physiologic Target, Molecular Evolution, and Pathogenic Functions of a Monoclonal Anti–Citrullinated Protein Antibody Obtained From a Patient With Rheumatoid Arthritis 2020 ·Arthritis & Rheumatology ·Tatsuhiko Ozawa,Kazuhisa Ouhara,(unknown),(unknown),Hidemi Kurihara,(unknown),Hiroshi Hamana,Eiji Kobayashi,Hirofumi Taki,Kazuyuki Tobe,Eiji Sugiyama,Atsushi Muraguchi,Hiroyuki Kishi	7
7	Association of Tumor PD-L1 Expression with the T790M Mutation and Progression-Free Survival in Patients with EGFR-Mutant Non-Small Cell Lung Cancer Receiving EGFR-TKI Therapy 2020 ·Diagnostics ·Minehiko Inomata,(unknown),Naoki Takata,(unknown),(unknown),(unknown),Seisuke Okazawa,Kenta Kambara,Shingo Imanishi,Toshiro Miwa,Ryuji Hayashi,Shoko Matsui,Kazuyuki Tobe	13
8	CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells 2019 ·Nature Immunology ·Tomomi Ichikawa,Kiyoshi Hirahara,Kota Kokubo,Masahiro Kiuchi,Ami Aoki,Yuki Morimoto,Jin Kumagai,Atsushi Onodera,Naoko Mato,Damon J. Tumes,Yoshiyuki Goto,Koichi Hagiwara,Yutaka Inagaki,Tim Sparwasser,Kazuyuki Tobe,Toshinori Nakayama	97
9	Clinical Parameters for Predicting the Survival in Patients with Squamous and Non-squamous-cell NSCLC Receiving PD-1 Inhibitor Therapy 2018 ·Pathology & Oncology Research ·Minehiko Inomata,(unknown),(unknown),(unknown),(unknown),Seisuke Okazawa,Kenta Kambara,Tomomi Ichikawa,Shingo Imanishi,Tōru Yamada,Toshiro Miwa,Ryuji Hayashi,Kazuyuki Tobe	18
10	Clinical Course After Initiation of Nivolumab Therapy in Patients with EGFR-Mutated Non-Small Cell Lung Cancer With or Without Pd-L1 Expression 2017 ·Oncology and Therapy ·Minehiko Inomata,Hiroaki Tanaka,(unknown),(unknown),Seisuke Okazawa,Kenta Kambara,Shingo Imanishi,Toru Yamada,Toshiro Miwa,Ryuji Hayashi,Kazuyuki Tobe	1
11	SIRT1 and FOXO1 mRNA expression in PBMC correlates to physical activity in COPD patients 2017 ·International Journal of COPD ·(unknown),Ryuji Hayashi,(unknown),(unknown),Seisuke Okazawa,Kenta Kambara,Minehiko Inomata,Toru Yamada,Shoko Matsui,Kazuyuki Tobe	19
12	CD206 positive intestinal macrophages contribute to the colonic epithelial wound healing 2017 ·(unknown),(unknown),(unknown),Kazuyuki Tobe,(unknown)	1
13	In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue 2008 ·Journal of Clinical Investigation ·Satoshi Nishimura,Ichiro Manabe,Masao Nagasaki,Kinya Seo,Hiroshi Yamashita,Yumiko Hosoya,Mitsuru Ohsugi,Kazuyuki Tobe,Takashi Kadowaki,Ryozo Nagai,Seiryo Sugiura	208
14	Glucokinase and IRS-2 are required for compensatory cell hyperplasia in response to high-fat diet-induced insulin resistance 2007 ·Journal of Clinical Investigation ·Yasuo Terauchi,(unknown),Naoto Kubota,Junji Matsui,Ryo Suzuki,Kajuro Komeda,Akemi Hara,Yusuke Toyoda,Ichitomo Miwa,Shin-Ichi Aizawa,Shogo Tsutsumi,Yoshiharu Tsubamoto,Shinji Hashimoto,Ko Eto,Akinobu Nakamura,Mitsuhiko Noda,Kazuyuki Tobe,Hiroyuki Aburatani,(unknown),Takashi Kadowaki	275
15	Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways 2006 ·Journal of Biological Chemistry ·Naoto Kubota,Yasuo Terauchi,Tetsuya Kubota,Hiroki Kumagai,Shinsuke Itoh,(unknown),Wataru Yano,Hitomi Ogata,Kumpei Tokuyama,Iseki Takamoto,Tomoka Mineyama,Michiro Ishikawa,Masao Moroi,Kaoru Sugi,Toshimasa Yamauchi,Kohjiro Ueki,Kazuyuki Tobe,Tetsuo Noda,Ryozo Nagai,Takashi Kadowaki	269
16	Insulin receptor substrate 2 plays a crucial role in β cells and the hypothalamus 2004 ·Journal of Clinical Investigation ·Naoto Kubota,Yasuo Terauchi,Kazuyuki Tobe,Wataru Yano,Ryo Suzuki,Kohjiro Ueki,Iseki Takamoto,(unknown),Toshiyuki Maki,Tetsuya Kubota,Masao Moroi,Miki Okada‐Iwabu,Osamu Ezaki,Ryozo Nagai,Yoichi Ueta,Takashi Kadowaki,Tetsuo Noda	189
17	SYSTEMATIZATION OF CRINICAL INFORMATION AND APPLICATION OF ADVANCED INFORMATION TECHNOLOGY TO MEDICAL SAFETY 2003 ·(unknown),Doubun Hayashi,Yasushi Imai,(unknown),(unknown),(unknown),(unknown),(unknown),Ichiro Manabe,Kazuyuki Tobe,Tsutomu Yamazaki,Ryozo Nagai	1
18	Constitutive Tyrosine Phosphorylation of ErbB-2 via Jak2 by Autocrine Secretion of Prolactin in Human Breast Cancer 2000 ·Journal of Biological Chemistry ·Toshimasa Yamauchi,Naoko Yamauchi,Kohjiro Ueki,Takuya Sugiyama,Hironori Waki,Hiroshi Miki,Kazuyuki Tobe,Satoru Matsuda,Toshio Tsushima,Tadashi Yamamoto,Toshiro Fujita,Yuji Taketani,Masashi Fukayama,Satoshi Kimura,Yoshio Yazaki,Ryozo Nagai,Takashi Kadowaki	75
19	Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease. 1997 ·Journal of Clinical Investigation ·Yasuo Terauchi,K Iwamoto,Hiroyuki Tamemoto,Kajuro Komeda,(unknown),Yasunori Kanazawa,(unknown),Toru Aizawa,Y Akanuma,Kazuki Yasuda,Takahiro Kodama,Kazuyuki Tobe,Y Yazaki,Takashi Kadowaki	108
20	Csk Enhances Insulin-Stimulated Dephosphorylation of Focal Adhesion Proteins 1996 ·Molecular and Cellular Biology ·Kazuyuki Tobe,Hisataka Sabe,Tadashi Yamamoto,Toshimasa Yamauchi,(unknown),Yasushi Kaburagi,Hiroyuki Tamemoto,Kohjiro Ueki,(unknown),Akanuma Yasuo,Yoshio Yazaki,Hidesaburô Hanafusa,Takashi Kadowaki	54

About Kazuyuki Tobe

Kazuyuki Tobe is a scholar working on Geriatrics and Gerontology, Endocrinology, Diabetes and Metabolism and Physiology, having authored 307 papers that have together received 18.5k indexed citations. Recurring topics across this work include Metabolism, Diabetes, and Cancer (66 papers), Adipose Tissue and Metabolism (51 papers) and Adipokines, Inflammation, and Metabolic Diseases (43 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (3.3k citations), Physiology (4.8k citations) and Geriatrics and Gerontology (664 citations). Kazuyuki Tobe has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Takashi Kadowaki, Toshimasa Yamauchi, Ryozo Nagai, Yasuo Terauchi, Yoshio Yazaki, Kohjiro Ueki, Naoto Kubota, Hiroyuki Tamemoto, Ryo Suzuki and Yasushi Kaburagi. Their work appears in journals such as Nature, Science and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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