Kirk R. Henne

3.5k citations

25 papers · 1.4k indexed · h-index 18

Pharmacology top 0.2%
Molecular Biology
Oncology top 10%
Computational Theory and Mathematics top 2%
Organic Chemistry top 10%

Co-authors: Allan E. Rettie Amit S. Kalgutkar William Trager Robert L. Haining Jason Boer Thomas H. Rushmore George Davis Deepak Dalvie
Topics: Pharmacogenetics and Drug Metabolism (12 papers)Drug Transport and Resistance Mechanisms (5 papers)Eicosanoids and Hypertension Pharmacology (5 papers)
Cited by: Pharmacology Biochemistry Computational Theory and Mathematics
Journals: Blood Biochemistry Biochemical and Biophysical Research Communications
Partner nations: United States Japan

In The Last Decade

Kirk R. Henne

25 papers receiving 1.3k citations

Peers

Countries citing papers authored by Kirk R. Henne

Since Specialization

Citations

This map shows the geographic impact of Kirk R. Henne's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kirk R. Henne with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kirk R. Henne more than expected).

Fields of papers citing papers by Kirk R. Henne

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kirk R. Henne. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kirk R. Henne. The network helps show where Kirk R. Henne may publish in the future.

Co-authorship network of co-authors of Kirk R. Henne

This figure shows the co-authorship network connecting the top 25 collaborators of Kirk R. Henne. A scholar is included among the top collaborators of Kirk R. Henne based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kirk R. Henne. Kirk R. Henne is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II 2020 ·International Journal of Molecular Sciences ·(unknown),Akhil Bhalla,Julie C. Ullman,Meng Fang,Ritesh Ravi,Annie Arguello,Elliot R. Thomsen,Buyankhishig Tsogtbaatar,Jing Guo,(unknown),Jason C. Dugas,Sonnet S. Davis,Suresh B. Poda,Kannan Gunasekaran,Simona Costanzo,Zachary K. Sweeney,Anastasia G. Henry,Jeffrey M. Harris,Kirk R. Henne,Giuseppe Astarita	11
2	Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement 2015 ·Journal of Pharmacology and Experimental Therapeutics ·Kirk R. Henne,Brandon Ason,Monique Howard,Wei Wang,Jeonghoon Sun,Jared Higbee,Jie Tang,(unknown),Ren Xu,Lei Zhou,Joyce Chan,Chadwick King,Derek E. Piper,Randal R. Ketchem,Mark L. Michaels,Simon Jackson,Marc W. Retter	20
3	Synthesis and SAR study of potent and selective PI3Kδ inhibitors 2015 ·Bioorganic & Medicinal Chemistry Letters ·Minna Bui,Xiaolin Hao,Youngsook Shin,Mario Cardozo,Xiaodong He,Kirk R. Henne,Julia Suchomel,John D. McCarter,Lawrence R. McGee,Tisha San Miguel,Julio C. Medina,Deanna Mohn,Thuy Tran,Sharon Wannberg,Jamie Wong,Simon Wong,Leeanne Zalameda,Daniela Metz,Timothy D. Cushing	18
4	Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme 2012 ·Drug Metabolism and Disposition ·Kirk R. Henne,Thuy Tran,Brooke M. VandenBrink,Dan A. Rock,(unknown),Raju Subramanian,(unknown),David M. Stresser,Yohannes Teffera,Simon Wong,Michael G. Johnson,Xiaoqi Chen,George Tonn,Bradley K. Wong	31
5	Discovery of potent and specific CXCR3 antagonists 2011 ·Bioorganic & Medicinal Chemistry Letters ·Xiaoqi Chen,Jeff Mihalic,(unknown),Darin J. Gustin,Jason Duquette,Xiaohui Du,Johann Chan,Zice Fu,Michael G. Johnson,An‐Rong Li,Kirk R. Henne,Timothy J. Sullivan,Bryan D. Lemon,Ji Ma,Shichang Miao,George Tonn,Tassie L. Collins,Julio C. Medina	14
6	Application of Automated Dried Blood Spot Sampling and LC–MS/MS for Pharmacokinetic Studies of AMG 517 in Rats 2011 ·Bioanalysis ·(unknown),(unknown),(unknown),Kirk R. Henne,Guifen Xu,(unknown),Christopher James,Philip Wong	17
7	Bioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug Interaction 2010 ·Drug Metabolism and Disposition ·Simon Wong,Peter W. Fan,Raju Subramanian,George Tonn,Kirk R. Henne,Michael G. Johnson,(unknown),Bradley K. Wong	9
8	Imidazo-pyrazine derivatives as potent CXCR3 antagonists 2009 ·Bioorganic & Medicinal Chemistry Letters ·Xiaohui Du,Darin J. Gustin,Xiaoqi Chen,Jason Duquette,Lawrence R. McGee,Zhulun Wang,Karen Ebsworth,Kirk R. Henne,Bryan D. Lemon,Ji Ma,Shichang Miao,(unknown),Timothy J. Sullivan,George Tonn,Tassie L. Collins,Julio C. Medina	29
9	A comparison of substrate dynamics in human CYP2E1 and CYP2A6 2006 ·Biochemical and Biophysical Research Communications ·John Harrelson,Kirk R. Henne,Darwin O. V. Alonso,Sidney D. Nelson	17
10	Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38α inhibitor: identification of an active metabolite in preclinical species and human liver microsomes 2006 ·Biopharmaceutics & Drug Disposition ·Amit S. Kalgutkar,Heather L. Hatch,(unknown),Nguyen Thi Thu Hang,Edna F. Choo,Kim F. McClure,Tim Taylor,Kirk R. Henne,(unknown),Mark A. Dombroski,Michael A. Letavic	29
11	Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4 2005 ·Chemico-Biological Interactions ·Amit S. Kalgutkar,Kirk R. Henne,Mary E. Lame,Alfin D. N. Vaz,(unknown),John R. Soglia,Sabrina X. Zhao,Cornelis E. C. A. Hop	38
12	A Comprehensive Listing of Bioactivation Pathways of Organic Functional Groups 2005 ·Current Drug Metabolism ·Amit S. Kalgutkar,Iain Gardner,R. Scott Obach,Christopher L. Shaffer,Ernesto Callegari,Kirk R. Henne,Abdul Mutlib,Deepak Dalvie,(unknown),Yasuhiro Nakai,John P. O’Donnell,Jason Boer,Shawn Harriman	435
13	BIOACTIVATION OF THE NONTRICYCLIC ANTIDEPRESSANT NEFAZODONE TO A REACTIVE QUINONE-IMINE SPECIES IN HUMAN LIVER MICROSOMES AND RECOMBINANT CYTOCHROME P450 3A4 2004 ·Drug Metabolism and Disposition ·Amit S. Kalgutkar,Alfin D. N. Vaz,Mary E. Lame,Kirk R. Henne,John R. Soglia,Sabrina X. Zhao,Yuri A. Abramov,Franco Lombardo,(unknown),Zachary S. Hendsch,Cornelis E. C. A. Hop	102
14	Genotyping and site-directed mutagenesis of a cytochrome P450 meander Pro-X-Arg motif critical to CYP4B1 catalysis 2003 ·Toxicology and Applied Pharmacology ·Yi Zheng,Kirk R. Henne,Patrick Charmley,Richard B. Kim,D. Gail McCarver,Erwin Cabacungan,Ronald N. Hines,Allan E. Rettie	22
15	Covalent Heme Binding to CYP4B1 via Glu310 and a Carbocation Porphyrin Intermediate 2003 ·Biochemistry ·(unknown),Brian R. Baer,M. Byron Kneller,Kirk R. Henne,Kent L. Kunze,Allan E. Rettie	30
16	Active Site Characteristics of CYP4B1 Probed with Aromatic Ligands 2001 ·Biochemistry ·Kirk R. Henne,Michael B. Fisher,K. R. Krishna Iyer,Dieter Lang,William Trager,Allan E. Rettie	19
17	Covalent Linkage of Prosthetic Heme to CYP4 Family P450 Enzymes 2001 ·Biochemistry ·Kirk R. Henne,Kent L. Kunze,(unknown),Peter Christmas,Roy J. Soberman,Allan E. Rettie	51
18	Chiral phase analysis of warfarin enantiomers in patient plasma in relation to CYP2C9 genotype 1998 ·Journal of Chromatography B Biomedical Sciences and Applications ·Kirk R. Henne,(unknown),(unknown),J. Steven Leeder,Allan E. Rettie	47
19	Genetic association between sensitivity to warfarin and expression of CYP2C93 1997 ·Pharmacogenetics* ·(unknown),Robert L. Haining,Kirk R. Henne,George Davis,Thomas H. Rushmore,William Trager,Allan E. Rettie	239
20	[Meningeal Arthus reaction and its influence on the cytologic aspects of the cerebrospinal fluid of virus related meningitis]. 1966 ·PubMed ·Kirk R. Henne	1

About Kirk R. Henne

Kirk R. Henne is a scholar working on Pharmacology, Biochemistry and Clinical Biochemistry, having authored 25 papers that have together received 1.4k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (12 papers), Drug Transport and Resistance Mechanisms (5 papers) and Eicosanoids and Hypertension Pharmacology (5 papers). The work is most often cited by research in Pharmacology (769 citations), Biochemistry (158 citations) and Computational Theory and Mathematics (246 citations). Kirk R. Henne has collaborated with scholars based in United States and Japan. Frequent co-authors include Allan E. Rettie, Amit S. Kalgutkar, William Trager, Robert L. Haining, Jason Boer, Thomas H. Rushmore, George Davis, Deepak Dalvie, Iain Gardner and Yasuhiro Nakai. Their work appears in journals such as Blood, Biochemistry and Biochemical and Biophysical Research Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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