Michael J. Munchhof

4.1k citations

30 papers · 1.6k indexed · 1 hit paper · h-index 16

Molecular Biology top 10%
Organic Chemistry top 5%
Oncology top 10%
Hematology top 5%
Genetics top 5%

Co-authors: A. I. MEYERS Todd VanArsdale Annelie Abrahamsson Hyog Young Kwon Tannishtha Reya Juyong Brian Kim Alan Chen David A. Rizzieri
Topics: Epigenetics and DNA Methylation (5 papers)Lipid metabolism and biosynthesis (4 papers)Cancer-related gene regulation (4 papers)
Cited by: Hematology Genetics Organic Chemistry
Journals: Nature Journal of the American Chemical Society Blood
Partner nations: United States Germany Brazil

In The Last Decade

Michael J. Munchhof

28 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

2009 676 citations Alan Chen, Catriona Jamieson et al. Nature profile →

Peers

Countries citing papers authored by Michael J. Munchhof

Since Specialization

Citations

This map shows the geographic impact of Michael J. Munchhof's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael J. Munchhof with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael J. Munchhof more than expected).

Fields of papers citing papers by Michael J. Munchhof

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael J. Munchhof. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael J. Munchhof. The network helps show where Michael J. Munchhof may publish in the future.

Co-authorship network of co-authors of Michael J. Munchhof

This figure shows the co-authorship network connecting the top 25 collaborators of Michael J. Munchhof. A scholar is included among the top collaborators of Michael J. Munchhof based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael J. Munchhof. Michael J. Munchhof is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Species differences in metabolism of EPZ015666, an oxetane-containing protein arginine methyltransferase-5 (PRMT5) inhibitor 2015 ·Xenobiotica ·Nathalie Rioux,Kenneth W. Duncan,(unknown),Xiu‐Sheng Miao,Elayne Chan-Penebre,Mikel P. Moyer,Michael J. Munchhof,Robert A. Copeland,Richard Chesworth,Nigel J. Waters	16
2	Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666 2015 ·ACS Medicinal Chemistry Letters ·Kenneth W. Duncan,Nathalie Rioux,P. Ann Boriack‐Sjodin,Michael J. Munchhof,Lawrence A. Reiter,Christina R. Majer,Lei Jin,L. Danielle Johnston,Elayne Chan-Penebre,(unknown),Margaret Porter Scott,Roy M. Pollock,Nigel J. Waters,J. Joshua Smith,Mikel P. Moyer,Robert A. Copeland,Richard Chesworth	103
3	Abstract C85: Identification of a novel potent selective SMYD3 inhibitor with oral bioavailability 2015 ·Molecular Cancer Therapeutics ·Lorna H. Mitchell,P. Ann Boriack‐Sjodin,Sherri Smith,Michael J. Thomenius,Nathalie Rioux,Michael J. Munchhof,James E. Mills,Christine R. Klaus,(unknown),Thomas V. Riera,Alejandra Raimondi,Suzanne L. Jacques,(unknown),Nigel J. Waters,Kevin W. Kuntz,Tim J. Wigle,Margaret Porter Scott,Robert A. Copeland,J. Joshua Smith,Richard Chesworth	0
4	Defining the key pharmacophore elements of PF-04620110: Discovery of a potent, orally-active, neutral DGAT-1 inhibitor 2013 ·Bioorganic & Medicinal Chemistry ·Robert L. Dow,(unknown),Jiancheng Li,E. Michael Gibbs,Angel Guzmán-Pérez,Jennifer L. LaPerle,Qifang Li,(unknown),Michael J. Munchhof,Mark Niosi,Leena Patel,Christian Perreault,(unknown),William J. Zavadoski	17
5	Exploratory Process Development of a Novel Diacylglycerol Acyltransferase-1 (DGAT-1) Inhibitor 2013 ·Organic Process Research & Development ·Andrei Shavnya,Yong Tao,(unknown),Kevin B. Bahnck,Michael J. Munchhof,Asaad Nematalla,(unknown),David R. Bill	6
6	Efficient Synthesis of 4-Amino-2-methoxy-7,8-dihydropyrido[4,3-d]pyrimidin-5-ones: Practical Access to a Novel Chemotype in the Development of DGAT-1 Inhibitors 2012 ·Synthesis ·Kevin B. Bahnck,Yong Tao,Andrei Shavnya,(unknown),(unknown),Gary E. Aspnes,(unknown),David R. Bill,Mark W. Bundesmann,Robert L. Dow,Kapil Karki,Tung B. K. Le,Qifang Li,Michael J. Munchhof,Asaad Nematalla,(unknown),Leena Patel,Christian Perreault,(unknown)	2
7	Design and synthesis of potent, orally-active DGAT-1 inhibitors containing a dioxino[2,3-d]pyrimidine core 2011 ·Bioorganic & Medicinal Chemistry Letters ·Robert L. Dow,(unknown),Gary E. Aspnes,(unknown),E. Michael Gibbs,Angel Guzmán-Pérez,Kapil Karki,Jennifer L. LaPerle,Jiancheng Li,John Litchfield,Michael J. Munchhof,Christian Perreault,Leena Patel	12
8	Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor 2011 ·Bioorganic & Medicinal Chemistry Letters ·Vincent Mascitti,Benjamin D. Stevens,Chulho Choi,Kim F. McClure,Cristiano R. W. Guimarães,Kathleen A. Farley,Michael J. Munchhof,Ralph P. Robinson,Kentaro Futatsugi,Sophie Y. Lavergne,Bruce A. Lefker,Peter Cornelius,Paul D. Bonin,Amit S. Kalgutkar,Raman Sharma,Yue Chen	21
9	Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1 2011 ·ACS Medicinal Chemistry Letters ·Robert L. Dow,Jiancheng Li,(unknown),E. Michael Gibbs,Jennifer L. LaPerle,John Litchfield,David W. Piotrowski,Michael J. Munchhof,(unknown),William J. Zavadoski,Gregory S. Walker,R. Kirk McPherson,(unknown),Eliot Sugarman,Angel Guzmán-Pérez,Paul DaSilva‐Jardine	70
10	Synthesis of 2,6-disubstituted-7,8-dihydro-6H-pyrano[2,3-6]pyrazines 2011 ·Tetrahedron Letters ·Jiancheng Li,Michael J. Munchhof,Joseph S. Warmus,Paul D. Bonin,Kim F. McClure	0
11	Structure–activity relationships and hepatic safety risks of thiazole agonists of the thrombopoietin receptor 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),(unknown),William H. Brissette,Matthew F. Brown,Jeffrey Casavant,Jonathan L. Doty,James P. Driscoll,Thomas M. Harris,Christopher S. Jones,Sandra P. McCurdy,Eric B. McElroy,Mark J. Mitton‐Fry,Michael J. Munchhof,(unknown),Lawrence A. Reiter,Sharon L. Ripp,Andrei Shavnya,(unknown),(unknown)	7
12	Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemiabreakdown → 2009 ·Nature ·(unknown),Alan Chen,Catriona Jamieson,Mark Fereshteh,Annelie Abrahamsson,Jordan Blum,Hyog Young Kwon,Juyong Brian Kim,John P. Chute,David A. Rizzieri,Michael J. Munchhof,Todd VanArsdale,Philip A. Beachy,Tannishtha Reya	676
13	Molecular features crucial to the activity of pyrimidine benzamide-based thrombopoietin receptor agonists 2008 ·Bioorganic & Medicinal Chemistry Letters ·Lawrence A. Reiter,Christopher S. Jones,William H. Brissette,Sandra P. McCurdy,Yuriy A. Abramov,Jon Bordner,Frank M. DiCapua,Michael J. Munchhof,(unknown),I. Samardjiev,Jane M. Withka	10
14	A Rational Chemical Intervention Strategy To Circumvent Bioactivation Liabilities Associated with a Nonpeptidyl Thrombopoietin Receptor Agonist Containing a 2-Amino-4-arylthiazole Motif 2007 ·Chemical Research in Toxicology ·Amit S. Kalgutkar,James P. Driscoll,Sabrina X. Zhao,Gregory S. Walker,Richard M. Shepard,John R. Soglia,James Atherton,Linning Yu,Abdul Mutlib,Michael J. Munchhof,Lawrence A. Reiter,Christopher S. Jones,(unknown),(unknown),Christopher L. Shaffer,Sharon L. Ripp	38
15	Design and SAR of thienopyrimidine and thienopyridine inhibitors of VEGFR-2 kinase activity 2003 ·Bioorganic & Medicinal Chemistry Letters ·Michael J. Munchhof,Jean S. Beebe,(unknown),Beth Cooper,Jonathan L. Doty,(unknown),Stephen Hillerman,Catherine Soderstrom,Elisabeth Knauth,Matthew A. Marx,Ann Marie Rossi,Susan B. Sobolov,Jianmin Sun	86
16	A Novel Asymmetric Route to the 1,3-Disubstituted Tetrahydroisoquinoline, (−)-Argemonine 1996 ·The Journal of Organic Chemistry ·Michael J. Munchhof,A. I. MEYERS	38
17	A Novel Asymmetric Route to Chiral, Nonracemic cis-2,6-Disubstituted Piperidines. Synthesis of (+)-Pinidinone and (+)-Monomorine 1995 ·Journal of the American Chemical Society ·Michael J. Munchhof,A. I. MEYERS	81
18	A Novel Route to Chiral, Nonracemic 1-Alkyl- and 1-Aryl-Substituted Tetrahydroisoquinolines. Synthesis of (-)-Salsolidine and (+)-Cryptostyline II 1995 ·The Journal of Organic Chemistry ·Michael J. Munchhof,A. I. MEYERS	30
19	An Asymmetric Route to Chiral, Nonracemic 2-Substituted Piperidines. Synthesis of (-)-Pipecoline, (+)-Coniine, and (-)-Coniceine 1995 ·The Journal of Organic Chemistry ·Michael J. Munchhof,A. I. MEYERS	66
20	The stereochemistry of enolate formation in THF-hexane mixtures 1992 ·Tetrahedron Letters ·Michael J. Munchhof,Clayton H. Heathcock	9

About Michael J. Munchhof

Michael J. Munchhof is a scholar working on Biochemistry, Hematology and Organic Chemistry, having authored 30 papers that have together received 1.6k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (5 papers), Lipid metabolism and biosynthesis (4 papers) and Cancer-related gene regulation (4 papers). The work is most often cited by research in Hematology (267 citations), Genetics (175 citations) and Organic Chemistry (413 citations). Michael J. Munchhof has collaborated with scholars based in United States, Germany and Brazil. Frequent co-authors include A. I. MEYERS, Todd VanArsdale, Annelie Abrahamsson, Hyog Young Kwon, Tannishtha Reya, Juyong Brian Kim, Alan Chen, David A. Rizzieri, Philip A. Beachy and Jordan Blum. Their work appears in journals such as Nature, Journal of the American Chemical Society and Blood.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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