Jay A. Markwalder

1.4k citations

18 papers · 897 indexed · h-index 13

Impact in

Virology top 10%
- HIV Research and Treatment
Biological Psychiatry top 10%

Papers in ⓘ

Molecular Biology 8
- Glycosylation and Glycoproteins Research 2
- Pharmacological Receptor Mechanisms and Effects 2
Organic Chemistry 7

Co-authors: Steven P. Seitz (12 shared papers)Benjamin Schwartz (2 shared papers)Yi Wang (1 shared paper)David D. Christ (3 shared papers)Abdul Mutlib (3 shared papers)Ross L. Stein (1 shared paper)Sharon Jackson (1 shared paper)Gregory A. Nemeth (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Journal of the American Chemical Society (2 papers)Molecular Cancer Therapeutics (1 paper)Tetrahedron Letters (1 paper)Journal of Computer-Aided Molecular Design (1 paper)
Partner nations: United States Germany Italy

In The Last Decade

Jay A. Markwalder

18 papers receiving 869 citations

Peers

Countries citing papers authored by Jay A. Markwalder

Since Specialization

Citations

This map shows the geographic impact of Jay A. Markwalder's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jay A. Markwalder with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jay A. Markwalder more than expected).

Fields of papers citing papers by Jay A. Markwalder

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jay A. Markwalder. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jay A. Markwalder. The network helps show where Jay A. Markwalder may publish in the future.

Co-authors

The 25 scholars most cited alongside Jay A. Markwalder, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jay A. Markwalder Line = papers co-authored together Jay A. Markwalder links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	Template-Constrained Cyclic Peptides: Design of High-Affinity Ligands for GPIIb/IIIa Journal of the American Chemical Society ·Sharon Jackson, William F. DeGrado, Anil Kumar Dwivedi, A. Parthasarathy, A. Higley, J. Krywko, Arlene L. Rockwell, Jay A. Markwalder, Gregory J. Wells	1994	140
2	Identification and Characterization of Efavirenz Metabolites by Liquid Chromatography/Mass Spectrometry and High Field NMR: Species Differences in the Metabolism of Efavirenz Drug Metabolism and Disposition ·Abdul Mutlib, Hua Chen, Gregory A. Nemeth, Jay A. Markwalder, Steven P. Seitz, L.‐S. Gan, David D. Christ	1999	113
3	Lipid II: Total Synthesis of the Bacterial Cell Wall Precursor and Utilization as a Substrate for Glycosyltransfer and Transpeptidation by Penicillin Binding Protein (PBP) 1b of Eschericia coli Journal of the American Chemical Society ·Benjamin Schwartz, Jay A. Markwalder, Yi Wang	2001	112
4	Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors Molecular Cancer Therapeutics ·Petra Ross‐Macdonald, Heshani de Silva, Qi Guo, Hong Xiao, Chen-Yi Hung, Becky Penhallow, Jay A. Markwalder, Liqi He, Ricardo M. Attar, Tai-An Lin, Steven P. Seitz, Charles Tilford, Judith Wardwell-Swanson, Donald Jackson	2008	102
5	A Kinetic Characterization of the Glycosyltransferase Activity of Eschericia coli PBP1b and Development of a Continuous Fluorescence Assay Biochemistry ·Benjamin Schwartz, Jay A. Markwalder, Steven P. Seitz, Yi Wang, Ross L. Stein	2002	100
6	Synthesis and evaluation of analogs of Efavirenz (SUSTIVATM) as HIV-1 reverse transcriptase inhibitors Bioorganic & Medicinal Chemistry Letters ·Mona Patel, Soo S. Ko, Robert J. McHugh, Jay A. Markwalder, Anurag Srivastava, Beverly C. Cordova, Ronald M. Klabe, Susan Erickson‐Viitanen, George L. Trainor, Steven P. Seitz	1999	65
7	The Species-Dependent Metabolism of Efavirenz Produces a Nephrotoxic Glutathione Conjugate in Rats Toxicology and Applied Pharmacology ·Abdul Mutlib, Ronald J. Gerson, Paul C. Meunier, Patrick J. Haley, Hao Chen, Lawrence S. Gan, Marc H. Davies, Brian Gemzik, David D. Christ, David F. Krahn, Jay A. Markwalder, Steven P. Seitz, Richard T. Robertson, Gerald T. Miwa	2000	62
8	Identification of selective inhibitors of cyclin dependent kinase 4 Bioorganic & Medicinal Chemistry Letters ·David J. Carini, Robert F. Kaltenbach, Jie Liu, Pamela A. Benfield, John F. Boylan, Michael D. Boisclair, Leonardo Brizuela, Catherine R. Burton, Sarah Cox, Robert H. Grafström, Barbara Harrison, Kimberly A. Harrison, Emeka Akamike, Jay A. Markwalder, Yuki Nakano, Steven P. Seitz, Diane M. Sharp, George L. Trainor, Thais M. Sielecki	2001	37
9	Synthesis and NMR conformational analysis of a β‐turn mimic incorporated into gramicidin S International journal of peptide & protein research ·A. Bach, Jay A. Markwalder, William C. Ripka	1991	31
10	Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3 Bioorganic & Medicinal Chemistry Letters ·Eddy W. Yue, Susan V. DiMeo, C. Anne Higley, Jay A. Markwalder, Catherine R. Burton, Pamela A. Benfield, Robert H. Grafström, Sarah Cox, J.K. Muckelbauer, Angela Smallwood, Haiying Chen, C.-H. Chang, George L. Trainor, Steven P. Seitz	2003	30
11	Identification and optimization of a novel series of indoleamine 2,3-dioxygenase inhibitors Bioorganic & Medicinal Chemistry Letters ·Jay A. Markwalder, Steven P. Seitz, Yuval Blat, Lisa Elkin, John T. Hunt, Jonathan G. Pabalan, Maria Jure–Kunkel, Gregory D. Vite, Kelly L. Covello	2016	23
12	Regulated Expression of the Escherichia coli lepB Gene as a Tool for Cellular Testing of Antimicrobial Compounds That Inhibit Signal Peptidase I In Vitro Antimicrobial Agents and Chemotherapy ·Maria D.F.S. Barbosa, Siqi Lin, Jay A. Markwalder, J.A.N. Mills, Joseph A. DeVito, Christopher A. Teleha, Vasudha Garlapati, Charles Y. Liu, A. Thompson, George L. Trainor, Michael G. Kurilla, David L. Pompliano	2002	16
13	Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors Bioorganic & Medicinal Chemistry Letters ·David Williams, Jay A. Markwalder, Aaron Balog, Bin Chen, Libing Chen, Jennifer S. Donnell, Lauren Haque, Amy C. Hart, Sunil K. Mandal, Andrew Nation, Weifang Shan, Gregory D. Vite, Kelly L. Covello, John T. Hunt, Maria Jure–Kunkel, Steven P. Seitz	2018	15
14	Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor Efavirenz Bioorganic & Medicinal Chemistry Letters ·Jay A. Markwalder, David D. Christ, Abdul Mutlib, Beverly C. Cordova, Ronald M. Klabe, Steven P. Seitz	2001	12
15	One-Pot Conversion of α-Thioureido Esters to Imidazol-2-ones and Imidazole-2-thiones Synlett ·Jay A. Markwalder, Richard S. Pottorf, Steven P. Seitz	1997	12
16	Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors Journal of Computer-Aided Molecular Design ·Karen A. Rossi, Jay A. Markwalder, Steven P. Seitz, Chong‐Hwan Chang, Sarah Cox, Michael D. Boisclair, Leonardo Brizuela, Stephen L. Brenner, Pieter F. W. Stouten	2005	10
17	3,3a-Dihydropyrano[4,3,2-de]quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeffrey W. Corbett, Senliang Pan, Jay A. Markwalder, Beverly C. Cordova, Ronald M. Klabe, Sena Garber, James D. Rodgers, Susan Erickson‐Viitanen	2001	10
18	Remote double stereodiffrentiation in macrocylizations of α-alkoxyallylstannanes Tetrahedron Letters ·James A. Marshall, Jay A. Markwalder	1988	7

About Jay A. Markwalder

Jay A. Markwalder is a scholar working on Molecular Biology, Organic Chemistry, Oncology, Infectious Diseases and Cell Biology, having authored 18 papers that have together received 897 indexed citations. Recurring topics across this work include Microtubule and mitosis dynamics (4 papers), HIV/AIDS drug development and treatment (4 papers), Bacterial Genetics and Biotechnology (3 papers), Cancer-related Molecular Pathways (3 papers), Advanced Breast Cancer Therapies (3 papers), Tryptophan and brain disorders (2 papers), Glycosylation and Glycoproteins Research (2 papers) and Pharmacological Receptor Mechanisms and Effects (2 papers). The work is most often cited by research in Virology (69 citations), Biological Psychiatry (32 citations), Organic Chemistry (285 citations), Immunology and Allergy (53 citations) and Infectious Diseases (146 citations). Jay A. Markwalder has collaborated with scholars based in United States, Germany and Italy. Frequent co-authors include Steven P. Seitz, Benjamin Schwartz, Yi Wang, David D. Christ, Abdul Mutlib, Ross L. Stein, Yi Wang, Sharon Jackson, Gregory A. Nemeth and Arlene L. Rockwell. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of the American Chemical Society, Molecular Cancer Therapeutics, Tetrahedron Letters and Journal of Computer-Aided Molecular Design.

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