Yun Chen

14.3k total citations · 3 hit papers
84 papers, 5.9k citations indexed

About

Yun Chen is a scholar working on Molecular Biology, Neurology and Immunology. According to data from OpenAlex, Yun Chen has authored 84 papers receiving a total of 5.9k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Molecular Biology, 21 papers in Neurology and 14 papers in Immunology. Recurrent topics in Yun Chen's work include Neuroinflammation and Neurodegeneration Mechanisms (15 papers), Mitochondrial Function and Pathology (11 papers) and Alzheimer's disease research and treatments (9 papers). Yun Chen is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (15 papers), Mitochondrial Function and Pathology (11 papers) and Alzheimer's disease research and treatments (9 papers). Yun Chen collaborates with scholars based in United States, China and Denmark. Yun Chen's co-authors include Gerald W. Dorn, Yingqiu Liu, Marco Colonna, Luca Scorrano, Esther Shohami, Marta Weinstock, Moshi Song, Katsuyoshi Mihara, David M. Holtzman and Albin Sandelin and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Yun Chen

81 papers receiving 5.8k citations

Hit Papers

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for... 2013 2026 2017 2021 2013 2015 2021 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
    2013 1.1k citations Yun Chen, Gerald W. Dorn Science profile →
  2. Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts
    2015 394 citations Yun Chen, Luca Scorrano et al. profile →
  3. Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice?
    2021 196 citations Yun Chen, Marco Colonna The Journal of Experimental Medicine profile →

Peers

Yun Chen
Satoshi O. Suzuki Japan
Demetrios G. Vavvas United States
Gerald W. Dorn United States
Jianhua Qiu United States
R. Anne Stetler United States
M. Zameel Cader United Kingdom
Yumin Luo China
Zengqiang Yuan China
Shinji Saiki Japan
Satoshi O. Suzuki Japan
Yun Chen
Citations per year, relative to Yun Chen Yun Chen (= 1×) peers Satoshi O. Suzuki

Countries citing papers authored by Yun Chen

Since Specialization
Citations

This map shows the geographic impact of Yun Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yun Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yun Chen more than expected).

Fields of papers citing papers by Yun Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yun Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yun Chen. The network helps show where Yun Chen may publish in the future.

Co-authorship network of co-authors of Yun Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Yun Chen. A scholar is included among the top collaborators of Yun Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yun Chen. Yun Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Parhizkar, Samira, Xin Bao, Yun Chen, et al.. (2025). Lemborexant ameliorates tau-mediated sleep loss and neurodegeneration in males in a mouse model of tauopathy. Nature Neuroscience. 28(7). 1460–1472. 1 indexed citations
2.
Zhu, Jingyu, Lei Xu, Yanfei Cai, et al.. (2024). Optimization of virtual screening against phosphoinositide 3-kinase delta: Integration of common feature pharmacophore and multicomplex-based molecular docking. Computational Biology and Chemistry. 109. 108011–108011. 7 indexed citations
3.
Chen, Yun, et al.. (2024). Atypical neurological manifestations in anti-IgLON5 disease: a case report. Frontiers in Neurology. 15. 1340284–1340284. 1 indexed citations
4.
Chen, Yun & Jason D. Ulrich. (2024). Seq-ing mechanisms behind types of Alzheimer’s disease. Neuron. 112(11). 1723–1724. 2 indexed citations
5.
Strickland, Michael R., Michael Rau, Katherine Basore, et al.. (2024). Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins. Neuron. 112(7). 1100–1109.e5. 11 indexed citations
6.
Sun, Rui, Rowland H. Han, Saad M. Khan, et al.. (2023). TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma. Science Advances. 9(19). eade3559–eade3559. 62 indexed citations
7.
Haensel, Daniel, Bence Dániel, Sadhana Gaddam, et al.. (2023). Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche. Nature Communications. 14(1). 2685–2685. 19 indexed citations
8.
Bressan, Raul Bardini, Jordi Guiu, Yun Chen, et al.. (2023). Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation. Science Advances. 9(28). eadf9460–eadf9460. 22 indexed citations
9.
Chen, Yun & Marco Colonna. (2022). Spontaneous and induced adaptive immune responses in Alzheimer’s disease: new insights into old observations. Current Opinion in Immunology. 77. 102233–102233. 8 indexed citations
10.
Gratuze, Maud, Yun Chen, Samira Parhizkar, et al.. (2021). Activated microglia mitigate Aβ-associated tau seeding and spreading. The Journal of Experimental Medicine. 218(8). 134 indexed citations
11.
Chen, Yun & Marco Colonna. (2021). Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice?. The Journal of Experimental Medicine. 218(9). 196 indexed citations breakdown →
12.
Zheng, Tingting, Jiao Peng, Yu Shi, et al.. (2019). Cornel iridoid glycoside exerts a neuroprotective effect on neuroinflammation in rats with brain injury by inhibiting NF-κB and STAT3. 3 Biotech. 9(5). 195–195. 11 indexed citations
13.
Chen, Yun, et al.. (2018). Repurposing drugs to target the malaria parasite unfolding protein response. Scientific Reports. 8(1). 10333–10333. 27 indexed citations
14.
Chen, Yun, Athma A. Pai, Michał Lubas, et al.. (2016). Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters. Nature Genetics. 48(9). 984–994. 64 indexed citations
15.
Kasahara, Atsuko, Sara Cipolat, Yun Chen, Gerald W. Dorn, & Luca Scorrano. (2013). Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling. Science. 342(6159). 734–737. 287 indexed citations
16.
Chen, Yun & Gerald W. Dorn. (2013). PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria. Science. 340(6131). 471–475. 1055 indexed citations breakdown →
17.
Chen, Yun, et al.. (2013). Mitochondrial Genome Linearization Is a Causative Factor for Cardiomyopathy in Mice and Drosophila. Antioxidants and Redox Signaling. 21(14). 1949–1959. 21 indexed citations
18.
Chen, Yun, Keith F. Decker, Dali Zheng, et al.. (2013). A Nucleus-targeted Alternately Spliced Nix/Bnip3L Protein Isoform Modifies Nuclear Factor κB (NFκB)-mediated Cardiac Transcription. Journal of Biological Chemistry. 288(22). 15455–15465. 12 indexed citations
19.
Qiu, Peiju, Huashi Guan, Ping Dong, et al.. (2011). The inhibitory effects of 5‐hydroxy‐3,6,7,8,3′,4′‐hexamethoxyflavone on human colon cancer cells. Molecular Nutrition & Food Research. 55(10). 1523–1532. 33 indexed citations
20.
Chen, Yun, King‐Jen Chang, Lih‐Hwa Hwang, Chiung‐Nien Chen, & Sheng-Hong Tseng. (2002). Establishment and characterization of a rectal cancer model in mice: application to cytokine gene therapy. International Journal of Colorectal Disease. 17(6). 388–395. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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